A multifunctional nanocarrier for efficient TRAIL-based gene therapy against hepatocellular carcinoma with desmoplasia in mice

Telomerase-specific oncolytic adenovirus expressing TRAIL suppresses peritoneal dissemination of gastric cancer

(2017) W Zhou et al.   GENE THERAPY

A novel cationic lipid with intrinsic antitumor activity to facilitate gene therapy of TRAIL DNA

(2016) Cong Luo et al.   BIOMATERIALS

Targeting Tumor-Associated Fibroblasts for Therapeutic Delivery in Desmoplastic Tumors

(2016) Lei Miao et al.   CANCER RESEARCH

Onto better TRAILs for cancer treatment

(2016) D de Miguel et al.   CELL DEATH AND DIFFERENTIATION

Systemic PEGylated TRAIL treatment ameliorates liver cirrhosis in rats by eliminating activated hepatic stellate cells

(2016) Yumin Oh et al.   HEPATOLOGY

Overcoming resistance to TRAIL-induced apoptosis in solid tumor cells by simultaneously targeting death receptors, c-FLIP and IAPs

(2016) YING HUANG et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Local and transient gene expression primes the liver to resist cancer metastasis

(2016) T. J. Goodwin et al.   Science Translational Medicine

Triazine-modified dendrimer for efficient TRAIL gene therapy in osteosarcoma

(2015) Yu Wang et al.   Acta Biomaterialia

CXCR4 inhibition in tumor microenvironment facilitates anti-programmed death receptor-1 immunotherapy in sorafenib-treated hepatocellular carcinoma in mice

(2015) Yunching Chen et al.   HEPATOLOGY

An orthotopic mouse model of hepatocellular carcinoma with underlying liver cirrhosis

(2015) Thomas Reiberger et al.   Nature Protocols

Nanoparticle-Mediated Target Delivery of TRAIL as Gene Therapy for Glioblastoma

(2015) Kui Wang et al.   Advanced Healthcare Materials

Getting TRAIL back on track for cancer therapy

(2014) J Lemke et al.   CELL DEATH AND DIFFERENTIATION

Death receptor agonist therapies for cancer, which is the right TRAIL?

(2013) Pamela M. Holland   CYTOKINE & GROWTH FACTOR REVIEWS

Role of the Microenvironment in the Pathogenesis and Treatment of Hepatocellular Carcinoma

(2013) Virginia Hernandez–Gea et al.   GASTROENTEROLOGY

Differential effects of sorafenib on liver versus tumor fibrosis mediated by stromal-derived factor 1 alpha/C-X-C receptor type 4 axis and myeloid differentiation antigen-positive myeloid cell infiltration in mice

(2013) Yunching Chen et al.   HEPATOLOGY

Co-delivery of TRAIL gene enhances the anti-glioblastoma effect of paclitaxel in vitro and in vivo

(2012) Changyou Zhan et al.   JOURNAL OF CONTROLLED RELEASE

TNF-related apoptosis-inducing ligand (TRAIL) exerts therapeutic efficacy for the treatment of pneumococcal pneumonia in mice

(2012) Kathrin Steinwede et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Adhesion receptors as therapeutic targets for circulating tumor cells

(2012) Jiahe Li et al.   Frontiers in Oncology

Sorafenib sensitizes hepatocellular carcinoma cells to physiological apoptotic stimuli

(2011) Joan Fernando et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Calcium phosphate nanoparticles with an asymmetric lipid bilayer coating for siRNA delivery to the tumor

(2011) Jun Li et al.   JOURNAL OF CONTROLLED RELEASE

TNF-related apoptosis-inducing ligand (TRAIL) regulates inflammatory neutrophil apoptosis and enhances resolution of inflammation

(2011) Emmet E. McGrath et al.   JOURNAL OF LEUKOCYTE BIOLOGY

A Novel Combination Treatment of Armed Oncolytic Adenovirus Expressing IL-12 and GM-CSF with Radiotherapy in Murine Hepatocarcinoma

(2011) Wonwoo KIM et al.   JOURNAL OF RADIATION RESEARCH

Targeting Cell Spreading: A Method of Sensitizing Metastatic Tumor Cells to TRAIL-Induced Apoptosis

(2011) L. E. Phipps et al.   MOLECULAR CANCER RESEARCH

HCC and angiogenesis: possible targets and future directions

(2011) Andrew X. Zhu et al.   Nature Reviews Clinical Oncology

NF-κB in the liver—linking injury, fibrosis and hepatocellular carcinoma

(2011) Tom Luedde et al.   Nature Reviews Gastroenterology & Hepatology

Capsaicin sensitizes TRAIL-induced apoptosis through Sp1-mediated DR5 up-regulation: Involvement of Ca2+ influx

(2011) Dong-Oh Moon et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Sorafenib Overcomes TRAIL Resistance of Hepatocellular Carcinoma Cells through the Inhibition of STAT3

(2010) K.-F. Chen et al.   CLINICAL CANCER RESEARCH

The Etiology of Hepatocellular Carcinoma and Consequences for Treatment

(2010) A. J. Sanyal et al.   ONCOLOGIST

TRAIL Gene Therapy: From Preclinical Development to Clinical Application

(2009) Thomas Griffith et al.   CURRENT GENE THERAPY

Combination of antiangiogenesis with chemotherapy for more effective cancer treatment

(2008) J. Ma et al.   MOLECULAR CANCER THERAPEUTICS