Capicua suppresses hepatocellular carcinoma progression by controlling the ETV4-MMP1 axis

Hepatocellular carcinoma surveillance: The road ahead

(2017) Ruben Hernaez et al.   HEPATOLOGY

Comparative transcriptome analysis of isogenic cell line models and primary cancers links capicua (CIC) loss to activation of the MAPK signalling cascade

(2017) Veronique G LeBlanc et al.   JOURNAL OF PATHOLOGY

Disruption of the ATXN1–CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans

(2017) Hsiang-Chih Lu et al.   NATURE GENETICS

Targeting the Ras/Raf/MEK/ERK pathway in hepatocellular carcinoma

(2017) Sufang Yang et al.   Oncology Letters

Capicua deficiency induces autoimmunity and promotes follicular helper T cell differentiation via derepression of ETV5

(2017) Sungjun Park et al.   Nature Communications

A new mode of DNA binding distinguishes Capicua from other HMG-box factors and explains its mutation patterns in cancer

(2017) Marta Forés et al.   PLoS Genetics

Inactivation of Capicua drives cancer metastasis

(2016) Ross A Okimoto et al.   NATURE GENETICS

Minibrain and Wings apart control organ growth and tissue patterning through down-regulation of Capicua

(2016) Liu Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Ras/Raf/MEK/ERK signaling pathway and its role in the occurrence and development of HCC

(2016) Lei Li et al.   Oncology Letters

CICinactivating mutations identify aggressive subset of 1p19q codeleted gliomas

(2015) Vincent Gleize et al.   ANNALS OF NEUROLOGY

Genetic Landscape and Biomarkers of Hepatocellular Carcinoma

(2015) Jessica Zucman-Rossi et al.   GASTROENTEROLOGY

Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets

(2015) Kornelius Schulze et al.   NATURE GENETICS

Advances in targeted therapies for hepatocellular carcinoma in the genomic era

(2015) Josep M. Llovet et al.   Nature Reviews Clinical Oncology

Mapping the binding interface of ERK and transcriptional repressor Capicua using photocrosslinking

(2015) Alan S. Futran et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New molecular therapies for hepatocellular carcinoma

(2015) S. Torrecilla et al.   Clinics and Research in Hepatology and Gastroenterology

miR-93/miR-106b/miR-375-CIC-CRABP1: a novel regulatory axis in prostate cancer progression

(2015) Nahyun Choi et al.   Oncotarget

Deficiency of Capicua disrupts bile acid homeostasis

(2015) Eunjeong Kim et al.   Scientific Reports

EGFR/Ras Signaling Controls Drosophila Intestinal Stem Cell Proliferation via Capicua-Regulated Genes

(2015) Yinhua Jin et al.   PLoS Genetics

Mouse Matrix Metalloprotease-1a (Mmp1a) Gives New Insight Into MMP Function

(2014) Caitlin J. Foley et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Trans-ancestry mutational landscape of hepatocellular carcinoma genomes

(2014) Yasushi Totoki et al.   NATURE GENETICS

Expression and roles of fatty acid synthase in hepatocellular carcinoma

(2014) QIWEI HAO et al.   ONCOLOGY REPORTS

Torso RTK controls Capicua degradation by changing its subcellular localization

(2012) O. Grimm et al.   DEVELOPMENT

The Capicua repressor - a general sensor of RTK signaling in development and disease

(2012) G. Jimenez et al.   JOURNAL OF CELL SCIENCE

Hepatocellular carcinoma

(2012) Alejandro Forner et al.   LANCET

Activation of androgen receptor induces ID1 and promotes hepatocellular carcinoma cell migration and invasion

(2012) Junping Ao et al.   Molecular Oncology

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Capicua DNA-binding sites are general response elements for RTK signaling in Drosophila

(2011) L. Ajuria et al.   DEVELOPMENT

ATXN1 Protein Family and CIC Regulate Extracellular Matrix Remodeling and Lung Alveolarization

(2011) Yoontae Lee et al.   DEVELOPMENTAL CELL

Overexpression of matrix metalloproteinase-12 (MMP-12) correlates with poor prognosis of hepatocellular carcinoma

(2011) Kevin Tak-Pan Ng et al.   EUROPEAN JOURNAL OF CANCER

Hepatocellular Carcinoma

(2011) Hashem B. El-Serag   NEW ENGLAND JOURNAL OF MEDICINE

Mutations in CIC and FUBP1 Contribute to Human Oligodendroglioma

(2011) C. Bettegowda et al.   SCIENCE

Exercise and Genetic Rescue of SCA1 via the Transcriptional Repressor Capicua

(2011) J. D. Fryer et al.   SCIENCE

ERK/p90RSK/14-3-3 signalling has an impact on expression of PEA3 Ets transcription factors via the transcriptional repressor capicúa

(2010) Kumara Dissanayake et al.   BIOCHEMICAL JOURNAL

Diverse somatic mutation patterns and pathway alterations in human cancers

(2010) Zhengyan Kan et al.   NATURE

Hepatocellular carcinoma: current trends in worldwide epidemiology, risk factors, diagnosis and therapeutics

(2009) Mohamed IF Shariff et al.   Expert Review of Gastroenterology & Hepatology

Sorafenib in Advanced Hepatocellular Carcinoma

(2008) Josep M. Llovet et al.   NEW ENGLAND JOURNAL OF MEDICINE