Trends of LSD1 inhibitors in viral infections

Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors

(2018) Jay H. Kalin et al.   Nature Communications

A comprehensive review of lysine-specific demethylase 1 and its roles in cancer

(2017) Amir Hosseini et al.   Epigenomics

Histone demethylase LSD1 restricts influenza A virus infection by erasing IFITM3-K88 monomethylation

(2017) Jiaoyu Shan et al.   PLoS Pathogens

LSD1 inhibitors: a patent review (2010-2015)

(2016) Giulia Stazi et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

LSD1 binds to HPV16 E7 and promotes the epithelial-mesenchymal transition in cervical cancer by demethylating histones at the Vimentin promoter

(2016) Yuan Liu et al.   Oncotarget

The enzymes LSD1 and Set1A cooperate with the viral protein HBx to establish an active hepatitis B viral chromatin state

(2016) Valentina Alarcon et al.   Scientific Reports

Emerging approaches for histone deacetylase inhibitor drug discovery

(2015) Clemens Zwergel et al.   Expert Opinion on Drug Discovery

A Systematic Review of Histone Lysine-Specific Demethylase 1 and Its Inhibitors

(2015) Yi-Chao Zheng et al.   MEDICINAL RESEARCH REVIEWS

LSD1n is an H4K20 demethylase regulating memory formation via transcriptional elongation control

(2015) Jianxun Wang et al.   NATURE NEUROSCIENCE

The Role of the CoREST/REST Repressor Complex in Herpes Simplex Virus 1 Productive Infection and in Latency

(2013) Guoying Zhou et al.   Viruses-Basel

Activation of HIV Transcription by the Viral Tat Protein Requires a Demethylation Step Mediated by Lysine-specific Demethylase 1 (LSD1/KDM1)

(2011) Naoki Sakane et al.   PLoS Pathogens

Disruption of HDAC/CoREST/REST repressor by dnREST reduces genome silencing and increases virulence of herpes simplex virus

(2010) T. Du et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New roles of flavoproteins in molecular cell biology: Histone demethylase LSD1 and chromatin

(2009) Federico Forneris et al.   FEBS Journal

Engagement of the Lysine-Specific Demethylase/HDAC1/CoREST/REST Complex by Herpes Simplex Virus 1

(2009) H. Gu et al.   JOURNAL OF VIROLOGY

Inhibition of the histone demethylase LSD1 blocks α-herpesvirus lytic replication and reactivation from latency

(2009) Yu Liang et al.   NATURE MEDICINE