期刊
FRONTIERS IN BIOSCIENCE-LANDMARK
卷 23, 期 -, 页码 640-655出版社
FRONTIERS IN BIOSCIENCE INC
DOI: 10.2741/4610
关键词
Amino acid; Blood plasma; Homeostatic regulation; Dietary supply; Swine; Review
资金
- Hatch/Multistate Project funded through the USDA National Institute of Food and Agriculture [1007691]
- Agriculture and Food Research Initiative Competitive Grants - USDA National Institute of Food and Agriculture [2014-67015-21770, 2015-67015-23276]
- Texas A&M AgriLife Research [H-8200]
- NIFA [2014-67015-21770, 687803] Funding Source: Federal RePORTER
One major goal of nutrition is to maximize the rate of muscle protein gain via provision of amino acids (AAs) through blood plasma. Comparing the plasma AA concentrations with the growth performance data can help to elucidate the metabolic mechanisms regulating plasma AA homeostasis, nutrient utilization, and intracellular protein turnover. Knowledge about the homeostatic regulation of plasma AA profile can aid in predicting dietary AA availabilities, the order of limiting AAs, and the whole body protein metabolism. Lysine, for example, is typically the first limiting AA in practical swine diets; however, our current knowledge is insufficient to draw a clear conclusion about the complex relationship between dietary lysine supply and plasma AA profiles. Thorough understanding of the effect of dietary AA supply on plasma AA profiles can help nutritionists to develop novel nutritional strategies to guide and improve dietary AA supplies. Further research is needed to study how different levels of dietary AAs, individually or in concert, affect the plasma concentrations of all AAs and related metabolites.
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