Sialic acids in biological and therapeutic processes: opportunities and challenges

Development of Globo-H Cancer Vaccine

(2015) Samuel J. Danishefsky et al.   ACCOUNTS OF CHEMICAL RESEARCH

Disubstituted sialic acid ligands targeting siglecs CD33 and CD22 associated with myeloid leukaemias and B cell lymphomas

(2014) Cory D. Rillahan et al.   Chemical Science

On-Chip Synthesis and Screening of a Sialoside Library Yields a High Affinity Ligand for Siglec-7

(2013) Cory D. Rillahan et al.   ACS Chemical Biology

A Vision for Vaccines Built from Fully Synthetic Tumor-Associated Antigens: From the Laboratory to the Clinic

(2013) Rebecca M. Wilson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Glycocalyx engineering reveals a Siglec-based mechanism for NK cell immunoevasion

(2013) Jason E Hudak et al.   Nature Chemical Biology

Antigen Delivery to Macrophages Using Liposomal Nanoparticles Targeting Sialoadhesin/CD169

(2012) Weihsu C. Chen et al.   PLoS One

Inhaled pan-selectin antagonist Bimosiamose attenuates airway inflammation in COPD

(2012) Henrik Watz et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Targeting Siglecs—A novel pharmacological strategy for immuno- and glycotherapy

(2011) Camilla Jandus et al.   BIOCHEMICAL PHARMACOLOGY

Targeting B lymphoma with nanoparticles bearing glycan ligands of CD22

(2011) Weihsu C. Chen et al.   LEUKEMIA & LYMPHOMA

Carbohydrate chemistry in drug discovery

(2011) M. Carmen Galan et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Consequences of the expression of sialylated antigens in breast cancer

(2010) Aurélie Cazet et al.   CARBOHYDRATE RESEARCH

Rapid Screening of Lectins for Multivalency Effects with a Glycodendrimer Microarray

(2010) Núria Parera Pera et al.   CHEMBIOCHEM

Low Molecular Weight Antagonists of the Myelin-Associated Glycoprotein: Synthesis, Docking, and Biological Evaluation

(2010) Stefanie Mesch et al.   JOURNAL OF MEDICINAL CHEMISTRY

Carbohydrate vaccines: developing sweet solutions to sticky situations?

(2010) Rena D. Astronomo et al.   NATURE REVIEWS DRUG DISCOVERY

Combined Approaches to the Synthesis and Study of Glycoproteins

(2009) Gonçalo J. L. Bernardes et al.   ACS Chemical Biology

Advances in the Biology and Chemistry of Sialic Acids

(2009) Xi Chen et al.   ACS Chemical Biology

Synthetic Approaches to the Neuraminidase Inhibitors Zanamivir (Relenza) and Oseltamivir Phosphate (Tamiflu) for the Treatment of Influenza

(2009) Javier Magano   CHEMICAL REVIEWS

Synthetic carbohydrate-based anticancer vaccines: the Memorial Sloan-Kettering experience

(2009) Jianglong Zhu et al.   Expert Review of Vaccines

Biologics through Chemistry: Total Synthesis of a Proposed Dual-Acting Vaccine Targeting Ovarian Cancer by Orchestration of Oligosaccharide and Polypeptide Domains

(2009) Jianglong Zhu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

From carbohydrate leads to glycomimetic drugs

(2009) Beat Ernst et al.   NATURE REVIEWS DRUG DISCOVERY

Structural insight into mammalian sialyltransferases

(2009) Francesco V Rao et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Siglecs as targets for therapy in immune-cell-mediated disease

(2009) Mary K. O’Reilly et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Combinatorial Chemoenzymatic Synthesis and High-Throughput Screening of Sialosides

(2008) Harshal A. Chokhawala et al.   ACS Chemical Biology

Sialoside Analogue Arrays for Rapid Identification of High Affinity Siglec Ligands

(2008) Ola Blixt et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Sialic acids in human health and disease

(2008) Ajit Varki   TRENDS IN MOLECULAR MEDICINE