Recent perspectives on the molecular basis of biofilm formation by Pseudomonas aeruginosa and approaches for treatment and biofilm dispersal

Pseudomonas aeruginosa Alginate Overproduction Promotes Coexistence with Staphylococcus aureus in a Model of Cystic Fibrosis Respiratory Infection

(2017) Dominique H. Limoli et al.   mBio

Pseudomonas aeruginosa Lifestyle: A Paradigm for Adaptation, Survival, and Persistence

(2017) M. Fata Moradali et al.   Frontiers in Cellular and Infection Microbiology

Synergy and Order Effects of Antibiotics and Phages in Killing Pseudomonas aeruginosa Biofilms

(2017) Waqas Nasir Chaudhry et al.   PLoS One

Chelation of Membrane-Bound Cations by Extracellular DNA Activates the Type VI Secretion System in Pseudomonas aeruginosa

(2016) Mike Wilton et al.   INFECTION AND IMMUNITY

Antibiotic resistance in Pseudomonas aeruginosa and alternative therapeutic options

(2016) Maitrayee Chatterjee et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

PilN Binding Modulates the Structure and Binding Partners of thePseudomonas aeruginosaType IVa Pilus Protein PilM

(2016) Matthew McCallum et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biofilm dispersion in Pseudomonas aeruginosa

(2016) Soo-Kyoung Kim et al.   JOURNAL OF MICROBIOLOGY

Singly Flagellated Pseudomonas aeruginosa Chemotaxes Efficiently by Unbiased Motor Regulation

(2016) Qiuxian Cai et al.   mBio

Oxylipins produced by Pseudomonas aeruginosa promote biofilm formation and virulence

(2016) Eriel Martínez et al.   Nature Communications

Raffinose, a plant galactoside, inhibits Pseudomonas aeruginosa biofilm formation via binding to LecA and decreasing cellular cyclic diguanylate levels

(2016) Han-Shin Kim et al.   Scientific Reports

Modular Approach to Select Bacteriophages Targeting Pseudomonas aeruginosa for Their Application to Children Suffering With Cystic Fibrosis

(2016) Victor Krylov et al.   Frontiers in Microbiology

Effects of norspermidine onPseudomonas aeruginosabiofilm formation and eradication

(2016) Lin Qu et al.   MicrobiologyOpen

Exopolysaccharide biosynthetic glycoside hydrolases can be utilized to disrupt and prevent Pseudomonas aeruginosa biofilms

(2016) P. Baker et al.   Science Advances

Extracellular DNA Acidifies Biofilms and Induces Aminoglycoside Resistance in Pseudomonas aeruginosa

(2015) Mike Wilton et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A small-molecule norspermidine and norspermidine-hosting polyelectrolyte coatings inhibit biofilm formation by multi-species wastewater culture

(2015) Xiurong Si et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Small colony variants ofPseudomonas aeruginosain chronic bacterial infection of the lung in cystic fibrosis

(2015) Thomas J Evans   Future Microbiology

RpoN Regulates Virulence Factors of Pseudomonas aeruginosa via Modulating the PqsR Quorum Sensing Regulator

(2015) Zhao Cai et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Controlling the Connections of Cells to the Biofilm Matrix

(2015) Matthew R. Parsek   JOURNAL OF BACTERIOLOGY

Pel is a cationic exopolysaccharide that cross-links extracellular DNA in thePseudomonas aeruginosabiofilm matrix

(2015) Laura K. Jennings et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The exopolysaccharide Psl-eDNA interaction enables the formation of a biofilm skeleton inPseudomonas aeruginosa

(2015) Shiwei Wang et al.   Environmental Microbiology Reports

Phenazine virulence factor binding to extracellular DNA is important for Pseudomonas aeruginosa biofilm formation

(2015) Theerthankar Das et al.   Scientific Reports

Virulence Factors of Pseudomonas aeruginosa Induce Both the Unfolded Protein and Integrated Stress Responses in Airway Epithelial Cells

(2015) Emily F. A. van ‘t Wout et al.   PLoS Pathogens

Role of small colony variants in persistence of Pseudomonas aeruginosa infections in cystic fibrosis lungs

(2015) Jacob Malone   Infection and Drug Resistance

Biofilms and Wounds: An Identification Algorithm and Potential Treatment Options

(2015) Steven L. Percival et al.   Advances in Wound Care

Cranberry proanthocyanidins have anti-biofilm properties against Pseudomonas aeruginosa

(2015) Robert K Ulrey et al.   BMC Complementary and Alternative Medicine

Pseudomonas aeruginosa Biofilm Formation and Persistence, along with the Production of Quorum Sensing-Dependent Virulence Factors, Are Disrupted by a Triterpenoid Coumarate Ester Isolated from Dalbergia trichocarpa, a Tropical Legume

(2015) Tsiry Rasamiravaka et al.   PLoS One

The Effect of Infection Control Nurses on the Occurrence of Pseudomonas aeruginosa Healthcare-Acquired Infection and Multidrug-Resistant Strains in Critically-Ill Children

(2015) Wei Xu et al.   PLoS One

Mechanisms of phagocytosis and host clearance of Pseudomonas aeruginosa

(2014) Rustin R. Lovewell et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

A Broad-Spectrum Antibiofilm Peptide Enhances Antibiotic Action against Bacterial Biofilms

(2014) Fany Reffuveille et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Synergy of Silver Nanoparticles and Aztreonam against Pseudomonas aeruginosa PAO1 Biofilms

(2014) Marc B. Habash et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Inhibition of Biofilm Formation by T7 Bacteriophages Producing Quorum-Quenching Enzymes

(2014) Ruoting Pei et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Biofilms in periprosthetic orthopedic infections

(2014) Stephen J McConoughey et al.   Future Microbiology

How Epigallocatechin Gallate Can Inhibit α-Synuclein Oligomer Toxicityin Vitro

(2014) Nikolai Lorenzen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biofilm-Related Infections: Bridging the Gap between Clinical Management and Fundamental Aspects of Recalcitrance toward Antibiotics

(2014) D. Lebeaux et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Influence of Calcium in Extracellular DNA Mediated Bacterial Aggregation and Biofilm Formation

(2014) Theerthankar Das et al.   PLoS One

Dynamic Remodeling of Microbial Biofilms by Functionally Distinct Exopolysaccharides

(2014) S. C. Chew et al.   mBio

Iron-Regulated Expression of Alginate Production, Mucoid Phenotype, and Biofilm Formation by Pseudomonas aeruginosa

(2014) J. R. Wiens et al.   mBio

The hierarchy quorum sensing network in Pseudomonas aeruginosa

(2014) Jasmine Lee et al.   Protein & Cell

The Pseudomonas aeruginosa AlgZR two-component system coordinates multiple phenotypes

(2014) Yuta Okkotsu et al.   Frontiers in Cellular and Infection Microbiology

Mimicking the host and its microenvironmentin vitrofor studying mucosal infections byPseudomonas aeruginosa

(2014) Aurélie Crabbé et al.   Pathogens and Disease

Catheter associated urinary tract infections

(2014) Lindsay E Nicolle   Antimicrobial Resistance and Infection Control

Extracellular DNA Shields against Aminoglycosides in Pseudomonas aeruginosa Biofilms

(2013) Wen-Chi Chiang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Interaction between extracellular lipase LipA and the polysaccharide alginate of Pseudomonas aeruginosa

(2013) Petra Tielen et al.   BMC MICROBIOLOGY

Photodynamic inactivation of biofilm: taking a lightly colored approach to stubborn infection

(2013) Wanessa CMA de Melo et al.   Expert Review of Anti-Infective Therapy

A study of the antibacterial mechanism of catechins: Isolation and identification of Escherichia coli cell surface proteins that interact with epigallocatechin gallate

(2013) Motokazu Nakayama et al.   FOOD CONTROL

Biofilm Matrix and Its Regulation in Pseudomonas aeruginosa

(2013) Qing Wei et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Which Bacterial Biofilm Exopolysaccharide Is Preferred, Psl or Alginate?

(2013) M. J. Schurr   JOURNAL OF BACTERIOLOGY

PelA Deacetylase Activity Is Required for Pel Polysaccharide Synthesis in Pseudomonas aeruginosa

(2013) K. M. Colvin et al.   JOURNAL OF BACTERIOLOGY

Biofilms 2012: New Discoveries and Significant Wrinkles in a Dynamic Field

(2013) S. Haussler et al.   JOURNAL OF BACTERIOLOGY

The MerR-Like Regulator BrlR Impairs Pseudomonas aeruginosa Biofilm Tolerance to Colistin by Repressing PhoPQ

(2013) J. R. Chambers et al.   JOURNAL OF BACTERIOLOGY

Antimicrobial Tolerance of Pseudomonas aeruginosa Biofilms Is Activated during an Early Developmental Stage and Requires the Two-Component Hybrid SagS

(2013) K. Gupta et al.   JOURNAL OF BACTERIOLOGY

Toward the Molecular Mechanism(s) by Which EGCG Treatment Remodels Mature Amyloid Fibrils

(2013) Fernando L. Palhano et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pseudomonas aeruginosa Biofilms in Disease

(2013) Lawrence R. Mulcahy et al.   MICROBIAL ECOLOGY

Exploiting Quorum Sensing To Confuse Bacterial Pathogens

(2013) B. LaSarre et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Cyclic di-GMP: the First 25 Years of a Universal Bacterial Second Messenger

(2013) U. Romling et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Identification of Genes Involved in Pseudomonas aeruginosa Biofilm-Specific Resistance to Antibiotics

(2013) Li Zhang et al.   PLoS One

Bacterial Biofilms: Development, Dispersal, and Therapeutic Strategies in the Dawn of the Postantibiotic Era

(2013) M. Kostakioti et al.   Cold Spring Harbor Perspectives in Medicine

The Extracellular Matrix Component Psl Provides Fast-Acting Antibiotic Defense in Pseudomonas aeruginosa Biofilms

(2013) Nicole Billings et al.   PLoS Pathogens

Pseudomonas aeruginosa: new insights into pathogenesis and host defenses

(2013) Shaan L. Gellatly et al.   Pathogens and Disease

Biophysics of biofilm infection

(2013) Philip S. Stewart   Pathogens and Disease

Host mucin glycosylation plays a role in bacterial adhesion in lungs of individuals with cystic fibrosis

(2013) Vignesh Venkatakrishnan et al.   Expert Review of Respiratory Medicine

Pseudomonas aeruginosa Exopolysaccharide Psl Promotes Resistance to the Biofilm Inhibitor Polysorbate 80

(2012) Michael E. Zegans et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Prevention and Treatment of Virulent Bacterial Biofilms with an Enzymatic Nitric Oxide-Releasing Dressing

(2012) Imran Sulemankhil et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Alginate Lyase Exhibits Catalysis-Independent Biofilm Dispersion and Antibiotic Synergy

(2012) John W. Lamppa et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Anti-infective properties of epigallocatechin-3-gallate (EGCG), a component of green tea

(2012) J Steinmann et al.   BRITISH JOURNAL OF PHARMACOLOGY

Molecular Basis of In Vivo Biofilm Formation by Bacterial Pathogens

(2012) Hwang-Soo Joo et al.   CHEMISTRY & BIOLOGY

Type IV Pilin Proteins: Versatile Molecular Modules

(2012) Carmen L. Giltner et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

The Pseudomonas aeruginosa Transcriptome in Planktonic Cultures and Static Biofilms Using RNA Sequencing

(2012) Andreas Dötsch et al.   PLoS One

Pyocyanin Promotes Extracellular DNA Release in Pseudomonas aeruginosa

(2012) Theerthankar Das et al.   PLoS One

Quorum Sensing and Bacterial Social Interactions in Biofilms

(2012) Yung-Hua Li et al.   SENSORS

Pseudomonas aeruginosa Pili and Flagella Mediate Distinct Binding and Signaling Events at the Apical and Basolateral Surface of Airway Epithelium

(2012) Iwona Bucior et al.   PLoS Pathogens

Guide to the elimination of orthopedic surgery surgical site infections: An executive summary of the Association for Professionals in Infection Control and Epidemiology elimination guide

(2011) Linda R. Greene   AMERICAN JOURNAL OF INFECTION CONTROL

Identification of a Novel Benzimidazole That Inhibits Bacterial Biofilm Formation in a Broad-Spectrum Manner

(2011) Karthik Sambanthamoorthy et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Human Serum Albumin as an Antioxidant in the Oxidation of (−)-Epigallocatechin Gallate: Participation of Reversible Covalent Binding for Interaction and Stabilization

(2011) Takeshi ISHII et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

The Pel and Psl polysaccharides provide Pseudomonas aeruginosa structural redundancy within the biofilm matrix

(2011) Kelly M. Colvin et al.   ENVIRONMENTAL MICROBIOLOGY

AFM study of the differential inhibitory effects of the green tea polyphenol (−)-epigallocatechin-3-gallate (EGCG) against Gram-positive and Gram-negative bacteria

(2011) Y. Cui et al.   FOOD MICROBIOLOGY

Recent developments for Pseudomonas vaccines

(2011) Anurag Sharma et al.   Human vaccines & immunotherapeutics

Extracellular DNA in Biofilms

(2011) Lucio Montanaro et al.   INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS

Nanoparticle silver ion coatings inhibit biofilm formation on titanium implants

(2011) Kutsal Devrim Secinti et al.   JOURNAL OF CLINICAL NEUROSCIENCE

The novel Pseudomonas aeruginosa two-component regulator BfmR controls bacteriophage-mediated lysis and DNA release during biofilm development through PhdA

(2011) Olga E. Petrova et al.   MOLECULAR MICROBIOLOGY

Why do microorganisms produce rhamnolipids?

(2011) Łukasz Chrzanowski et al.   WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY

The Pel Polysaccharide Can Serve a Structural and Protective Role in the Biofilm Matrix of Pseudomonas aeruginosa

(2011) Kelly M. Colvin et al.   PLoS Pathogens

Pseudomonas Aeruginosa: Resistance to the Max

(2011) Keith Poole   Frontiers in Microbiology

Biosynthesis of the Pseudomonas aeruginosa Extracellular Polysaccharides, Alginate, Pel, and Psl

(2011) Michael J. Franklin et al.   Frontiers in Microbiology

Spatial and Temporal Patterns of Biocide Action against Staphylococcus epidermidis Biofilms

(2010) W. M. Davison et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antibiofilm Activity of the Marine Bacterium Pseudoalteromonas sp. Strain 3J6

(2010) A. Dheilly et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Molecular mechanisms of compounds affecting bacterial biofilm formation and dispersal

(2010) Paolo Landini et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

An update onPseudomonas aeruginosabiofilm formation, tolerance, and dispersal

(2010) Morten Harmsen et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Biofilm Dispersal: Mechanisms, Clinical Implications, and Potential Therapeutic Uses

(2010) J.B. Kaplan   JOURNAL OF DENTAL RESEARCH

A bacterial extracellular DNA inhibits settling of motile progeny cells within a biofilm

(2010) Cécile Berne et al.   MOLECULAR MICROBIOLOGY

Evaluation of Enoyl-Acyl Carrier Protein Reductase Inhibitors as Pseudomonas aeruginosa Quorum-Quenching Reagents

(2010) Liang Yang et al.   MOLECULES

Quorum Sensing and Virulence of Pseudomonas aeruginosa during Lung Infection of Cystic Fibrosis Patients

(2010) Thomas Bjarnsholt et al.   PLoS One

EGCG remodels mature α-synuclein and amyloid-β fibrils and reduces cellular toxicity

(2010) Jan Bieschke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Pseudomonas aeruginosa Exopolysaccharide Psl Facilitates Surface Adherence and NF- B Activation in A549 Cells

(2010) M. S. Byrd et al.   mBio

Binding of epigallocatechin-3-gallate to transthyretin modulates its amyloidogenicity

(2009) Nelson Ferreira et al.   FEBS LETTERS

The GacS–GacA two-component regulatory system ofPseudomonas fluorescens: a bacterial two-hybrid analysis

(2009) Matthew L. Workentine et al.   FEMS MICROBIOLOGY LETTERS

Direct interaction between sensor kinase proteins mediates acute and chronic disease phenotypes in a bacterial pathogen

(2009) A. L. Goodman et al.   GENES & DEVELOPMENT

Evaluation of Flagella and Flagellin of Pseudomonas aeruginosa as Vaccines

(2009) V. L. Campodonico et al.   INFECTION AND IMMUNITY

Tea Catechins Induce the Conversion of Preformed Lysozyme Amyloid Fibrils to Amorphous Aggregates

(2009) Jing He et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Nitric Oxide Signaling in Pseudomonas aeruginosa Biofilms Mediates Phosphodiesterase Activity, Decreased Cyclic Di-GMP Levels, and Enhanced Dispersal

(2009) N. Barraud et al.   JOURNAL OF BACTERIOLOGY

Pseudomonas aeruginosa las and rhl quorum-sensing systems are important for infection and inflammation in a rat prostatitis model

(2009) L. K. Nelson et al.   MICROBIOLOGY-SGM

Genetic and biochemical analyses of thePseudomonas aeruginosaPsl exopolysaccharide reveal overlapping roles for polysaccharide synthesis enzymes in Psl and LPS production

(2009) Matthew S. Byrd et al.   MOLECULAR MICROBIOLOGY

A synergistic small-molecule combination directly eradicates diverse prion strain structures

(2009) Blake E Roberts et al.   Nature Chemical Biology

Assembly and Development of the Pseudomonas aeruginosa Biofilm Matrix

(2009) Luyan Ma et al.   PLoS Pathogens

MucR, a Novel Membrane-Associated Regulator of Alginate Biosynthesis in Pseudomonas aeruginosa

(2008) I. D. Hay et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Quorum sensing inPseudomonas aeruginosabiofilms

(2008) T. R. de Kievit   ENVIRONMENTAL MICROBIOLOGY

Covalent modification of proteins by green tea polyphenol (–)-epigallocatechin-3-gallate through autoxidation

(2008) Takeshi Ishii et al.   FREE RADICAL BIOLOGY AND MEDICINE

Scientific Status Summary

(2008) Bassam A. Annous et al.   JOURNAL OF FOOD SCIENCE

EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers

(2008) Dagmar E Ehrnhoefer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Bacterial adhesion and biofilms on surfaces

(2008) Trevor Roger Garrett et al.   Progress in Natural Science-Materials International