Sema4D/PlexinB1 inhibition ameliorates blood–brain barrier damage and improves outcome after stroke in rats

Mapping of Wnt-Frizzled interactions by multiplex CRISPR targeting of receptor gene families

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Method for Dual Viral Vector Mediated CRISPR-Cas9 Gene Disruption in Primary Human Endothelial Cells

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MicroRNA-150 regulates blood–brain barrier permeability via Tie-2 after permanent middle cerebral artery occlusion in rats

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TGF-beta1 regulates human brain pericyte inflammatory processes involved in neurovasculature function

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Pericytes as Inducers of Rapid, Matrix Metalloproteinase-9-Dependent Capillary Damage during Ischemia

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HIF-1α triggers long-lasting glutamate excitotoxicity via system xc − in cerebral ischaemia-reperfusion

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Targeted mRNA Decay by RNA Binding Protein AUF1 Regulates Adult Muscle Stem Cell Fate, Promoting Skeletal Muscle Integrity

(2016) Devon M. Chenette et al.   Cell Reports

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Blood−brain barrier breakdown and neovascularization processes after stroke and traumatic brain injury

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Anti-inflammatory strategies in stroke: a potential therapeutic target

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Effect of Sema4D on microglial function in middle cerebral artery occlusion mice

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High Serum MiR-130a Levels Are Associated with Severe Perihematomal Edema and Predict Adverse Outcome in Acute ICH

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(2015) Michael V. Sofroniew   NATURE REVIEWS NEUROSCIENCE

SEMA4D compromises blood–brain barrier, activates microglia, and inhibits remyelination in neurodegenerative disease

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RNA-stabilizing proteins as molecular targets in cardiovascular pathologies

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MicroRNA-107 contributes to post-stroke angiogenesis by targeting Dicer-1

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Antibody Blockade of Semaphorin 4D Promotes Immune Infiltration into Tumor and Enhances Response to Other Immunomodulatory Therapies

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Brain pericytes acquire a microglial phenotype after stroke

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Perivascular microglia promote blood vessel disintegration in the ischemic penumbra

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Endogenous Endothelial Progenitor Cells Participate in Neovascularization via CXCR4/SDF-1 axis and Improve Outcome After Stroke

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C-Type Natriuretic Peptide Modulates Permeability of the Blood–Brain Barrier

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Inhibition of junctional adhesion molecule-A/LFA interaction attenuates leukocyte trafficking and inflammation in brain ischemia/reperfusion injury

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The Semaphorin 4D-Plexin-B1-RhoA signaling axis recruits pericytes and regulates vascular permeability through endothelial production of PDGF-B and ANGPTL4

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Identification of a calmodulin-binding domain in Sema4D that regulates its exodomain shedding in platelets

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Blood-brain barrier disruption is associated with increased mortality after endovascular therapy

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Role of the Sphingosine Metabolism Pathway on Neurons Against Experimental Cerebral Ischemia in Rats

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Early Loss of Pericytes and Perivascular Stromal Cell-Induced Scar Formation after Stroke

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Inhalation of Nitric Oxide Prevents Ischemic Brain Damage in Experimental Stroke by Selective Dilatation of Collateral Arterioles

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Temporal pattern of expression and colocalization of microglia/macrophage phenotype markers following brain ischemic injury in mice

(2011) Carlo Perego et al.   Journal of Neuroinflammation

Differences in Origin of Reactive Microglia in Bone Marrow Chimeric Mouse and Rat After Transient Global Ischemia

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(2011) Berislav V. Zlokovic   NATURE REVIEWS NEUROSCIENCE

Blood–Brain Barrier Breakdown in Acute and Chronic Cerebrovascular Disease

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Roles of Sema4D and Plexin-B1 in tumor progression

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Pericytes are required for blood–brain barrier integrity during embryogenesis

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Heart Disease and Stroke Statistics—2009 Update

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Inflammation as a Therapeutic Target in Acute Ischemic Stroke Treatment

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Cerebral Ischemia–Reperfusion Injury in Rats—A 3 T MRI Study on Biphasic Blood–Brain Barrier Opening and the Dynamics of Edema Formation

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Roles of Sema4D-Plexin-B1 Interactions in the Central Nervous System for Pathogenesis of Experimental Autoimmune Encephalomyelitis

(2009) T. Okuno et al.   JOURNAL OF IMMUNOLOGY

Sema4D deficiency results in an increase in the number of oligodendrocytes in healthy and injured mouse brains

(2009) Yoshitaka Taniguchi et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Involvement of Sema4D in the control of microglia activation

(2009) Marcia Toguchi et al.   NEUROCHEMISTRY INTERNATIONAL

Blood-brain barrier tight junction permeability and ischemic stroke

(2008) Karin E. Sandoval et al.   NEUROBIOLOGY OF DISEASE

A new blood–brain barrier model using primary rat brain endothelial cells, pericytes and astrocytes

(2008) Shinsuke Nakagawa et al.   NEUROCHEMISTRY INTERNATIONAL