α-Ketoglutarate prevents skeletal muscle protein degradation and muscle atrophy through PHD3/ADRB2 pathway

PHD3 is a transcriptional coactivator of HIF-1α in nucleus pulposus cells independent of the PKM2-JMJD5 axis

(2017) Zachary R. Schoepflin et al.   FASEB JOURNAL

Androgen-mediated regulation of skeletal muscle protein balance

(2017) Michael L. Rossetti et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Cancer cachexia-induced muscle atrophy: evidence for alterations in microRNAs important for muscle size

(2017) David E. Lee et al.   PHYSIOLOGICAL GENOMICS

Molecular Regulation of Exercise-Induced Muscle Fiber Hypertrophy

(2017) Marcas M. Bamman et al.   Cold Spring Harbor Perspectives in Medicine

The golden retriever model of Duchenne muscular dystrophy

(2017) Joe N. Kornegay   Skeletal Muscle

Control of skeletal muscle atrophy in response to disuse: clinical/preclinical contentions and fallacies of evidence

(2016) Philip J. Atherton et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Three days of intermittent stretching after muscle disuse alters the proteins involved in force transmission in muscle fibers in weanling rats

(2016) M.C.S. Gianelo et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

Mechanisms of protein balance in skeletal muscle

(2016) T.G. Anthony   DOMESTIC ANIMAL ENDOCRINOLOGY

Distinct G protein–coupled receptor recycling pathways allow spatial control of downstream G protein signaling

(2016) Shanna Lynn Bowman et al.   JOURNAL OF CELL BIOLOGY

PHD3 Loss in Cancer Enables Metabolic Reliance on Fatty Acid Oxidation via Deactivation of ACC2

(2016) Natalie J. German et al.   MOLECULAR CELL

Prolyl hydroxylase 3 (PHD3) expression augments the development of regulatory T cells

(2016) Yogesh Singh et al.   MOLECULAR IMMUNOLOGY

Alpha-ketoglutarate promotes skeletal muscle hypertrophy and protein synthesis through Akt/mTOR signaling pathways

(2016) Xingcai Cai et al.   Scientific Reports

Role of IGF-I in follistatin-induced skeletal muscle hypertrophy

(2015) Caroline Barbé et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

SIRT5 regulation of ammonia-induced autophagy and mitophagy

(2015) Lucia Polletta et al.   Autophagy

The AKT/mTOR signaling pathway plays a key role in statin-induced myotoxicity

(2015) Annalisa Bonifacio et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Expression and localization of GPR91 and GPR99 in murine organs

(2015) Julia Diehl et al.   CELL AND TISSUE RESEARCH

PHD2/3-dependent hydroxylation tunes cardiac response to β-adrenergic stress via phospholamban

(2015) Liang Xie et al.   JOURNAL OF CLINICAL INVESTIGATION

mTOR inhibition activates overall protein degradation by the ubiquitin proteasome system as well as by autophagy

(2015) Jinghui Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of mTORC1 by PI3K signaling

(2015) Christian C. Dibble et al.   TRENDS IN CELL BIOLOGY

Activating cAMP/PKA signaling in skeletal muscle suppresses the ubiquitin-proteasome-dependent proteolysis: implications for sympathetic regulation

(2014) W. A. Silveira et al.   JOURNAL OF APPLIED PHYSIOLOGY

Lack of β2-adrenoceptors aggravates heart failure-induced skeletal muscle myopathy in mice

(2014) Vanessa A. Voltarelli et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Lysine suppresses protein degradation through autophagic–lysosomal system in C2C12 myotubes

(2014) Tomonori Sato et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

PHD3 regulates EGFR internalization and signalling in tumours

(2014) Boyan K. Garvalov et al.   Nature Communications

Regulation of muscle protein synthesis and the effects of catabolic states

(2013) Bradley S. Gordon et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Reduced Satellite Cell Numbers with Spinal Cord Injury and Aging in Humans

(2013) LEX B. VERDIJK et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

cAMP signaling in skeletal muscle adaptation: hypertrophy, metabolism, and regeneration

(2012) Rebecca Berdeaux et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Cellular and molecular mechanisms of muscle atrophy

(2012) P. Bonaldo et al.   Disease Models & Mechanisms

Prolyl Hydroxylase 3 (PHD3) Modulates Catabolic Effects of Tumor Necrosis Factor-α (TNF-α) on Cells of the Nucleus Pulposus through Co-activation of Nuclear Factor κB (NF-κB)/p65 Signaling

(2012) Nobuyuki Fujita et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Testosterone regulation of Akt/mTORC1/FoxO3a signaling in skeletal muscle

(2012) James P. White et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

HIF-independent role of prolyl hydroxylases in the cellular response to amino acids

(2012) R V Durán et al.   ONCOGENE

Clenbuterol suppresses proteasomal and lysosomal proteolysis and atrophy-related genes in denervated rat soleus muscles independently of Akt

(2011) Dawit A. P. Gonçalves et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Alpha-ketoglutarate inhibits glutamine degradation and enhances protein synthesis in intestinal porcine epithelial cells

(2011) Kang Yao et al.   AMINO ACIDS

Dual Function of Protein Kinase C (PKC) in 12-O-Tetradecanoylphorbol-13-acetate (TPA)-induced Manganese Superoxide Dismutase (MnSOD) Expression

(2011) Youn Wook Chung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

G i2 Signaling Promotes Skeletal Muscle Hypertrophy, Myoblast Differentiation, and Muscle Regeneration

(2011) G. C. Minetti et al.   Science Signaling

Alpha-Ketoglutarate and intestinal function

(2010) Yongqing Hou   Frontiers in Bioscience-Landmark

Using transcriptomics to identify and validate novel biomarkers of human skeletal muscle cancer cachexia

(2010) Nathan A Stephens et al.   Genome Medicine

Prolyl Hydroxylase-3 Is Down-regulated in Colorectal Cancer Cells and Inhibits IKKβ Independent of Hydroxylase Activity

(2009) Jing Xue et al.   GASTROENTEROLOGY

Oxygen-Regulated  2-Adrenergic Receptor Hydroxylation by EGLN3 and Ubiquitylation by pVHL

(2009) L. Xie et al.   Science Signaling

Lysosomal myopathies: An excessive build-up in autophagosomes is too much to handle

(2008) May Christine Malicdan et al.   NEUROMUSCULAR DISORDERS