Digital microfluidics comes of age: high-throughput screening to bedside diagnostic testing for genetic disorders in newborns

Incidence of 4 Lysosomal Storage Disorders From 4 Years of Newborn Screening

(2018) Patrick V. Hopkins et al.   JAMA Pediatrics

Enzyme replacement therapy and beyond—in memoriam Roscoe O. Brady, M.D. (1923–2016)

(2017) Markus Ries   JOURNAL OF INHERITED METABOLIC DISEASE

Enzymatic Functional Assays of Coagulation Using Small Sample Volumes

(2017) Sirisha Emani et al.   Labmedicine

Digital Microfluidics for Nucleic Acid Amplification

(2017) Beatriz Coelho et al.   SENSORS

Enzymatic Functional Assays of Coagulation Using Small Sample Volumes

(2017) Sirisha Emani et al.   LABORATORY MEDICINE

Newborn Screening for Lysosomal Storage Disorders:Quo Vadis?

(2016) Roy W.A. Peake et al.   CLINICAL CHEMISTRY

Lysosomal Storage Disorder Screening Implementation: Findings from the First Six Months of Full Population Pilot Testing in Missouri

(2015) Patrick V. Hopkins et al.   JOURNAL OF PEDIATRICS

Building bio-assays with magnetic particles on a digital microfluidic platform

(2015) Tadej Kokalj et al.   New Biotechnology

Point-of-Care Quantitative Measure of Glucose-6-Phosphate Dehydrogenase Enzyme Deficiency

(2015) V. K. Bhutani et al.   PEDIATRICS

Three-dimensional digital microfluidic manipulation of droplets in oil medium

(2015) Jiwoo Hong et al.   Scientific Reports

Diagnosis and therapy options in mucopolysaccharidosis II (Hunter syndrome)

(2015) Roberto Giugliani et al.   Expert Opinion on Orphan Drugs

Postanalytical tools improve performance of newborn screening by tandem mass spectrometry

(2014) Patricia L. Hall et al.   GENETICS IN MEDICINE

Digital Microfluidics: An Emerging Sample Preparation Platform for Mass Spectrometry

(2013) Andrea E. Kirby et al.   ANALYTICAL CHEMISTRY

Multiplex newborn screening for Pompe, Fabry, Hunter, Gaucher, and Hurler diseases using a digital microfluidic platform

(2013) Ramakrishna S. Sista et al.   CLINICA CHIMICA ACTA

Novel application of digital microfluidics for the detection of biotinidase deficiency in newborns

(2013) Carrie Graham et al.   CLINICAL BIOCHEMISTRY

Rapid assays for Gaucher and Hurler diseases in dried blood spots using digital microfluidics

(2013) Ramakrishna S. Sista et al.   MOLECULAR GENETICS AND METABOLISM

Pompe Disease: Early Diagnosis and Early Treatment Make a Difference

(2013) Yin-Hsiu Chien et al.   Pediatrics and Neonatology

Digital Microfluidics

(2012) Kihwan Choi et al.   Annual Review of Analytical Chemistry

Novel microfluidic platform for automated lab-on-chip testing of hypercoagulability panel

(2012) Sirisha Emani et al.   BLOOD COAGULATION & FIBRINOLYSIS

Lysosomal storage disorder 4+1 multiplex assay for newborn screening using tandem mass spectrometry: Application to a small-scale population study for five lysosomal storage disorders

(2012) Joseph J. Orsini et al.   CLINICA CHIMICA ACTA

Evaluation of a digital microfluidic real-time PCR platform to detect DNA of Candida albicans in blood

(2012) W. A. Schell et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Digital microfluidics: a versatile tool for applications in chemistry, biology and medicine

(2012) Mais J. Jebrail et al.   LAB ON A CHIP

A Pilot Newborn Screening Program for Lysosomal Storage Disorders (LSD) in Illinois

(2012) Barbara Burton et al.   MOLECULAR GENETICS AND METABOLISM

Rapid, single-step assay for Hunter syndrome in dried blood spots using digital microfluidics

(2011) Ramakrishna Sista et al.   CLINICA CHIMICA ACTA

Digital Microfluidic Platform for Multiplexing Enzyme Assays: Implications for Lysosomal Storage Disease Screening in Newborns

(2011) R. S. Sista et al.   CLINICAL CHEMISTRY

Applications of electrowetting-based digital microfluidics in clinical diagnostics

(2011) Michael G Pollack et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Newborn Bloodspot Screening for Lysosomal Storage Disorders

(2011) Hui Zhou et al.   JOURNAL OF PEDIATRICS

A novel fluorometric enzyme analysis method for Hunter syndrome using dried blood spots

(2011) Adviye A. Tolun et al.   MOLECULAR GENETICS AND METABOLISM

Newborn Screening of Lysosomal Storage Disorders

(2010) D. Marsden et al.   CLINICAL CHEMISTRY

Microfluidic platform versus conventional real-time polymerase chain reaction for the detection of Mycoplasma pneumoniae in respiratory specimens

(2010) Elizabeth Wulff-Burchfield et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Droplet-on-a-wristband: Chip-to-chip digital microfluidic interfaces between replaceable and flexible electrowetting modules

(2010) Shih-Kang Fan et al.   LAB ON A CHIP

Hemoglobin precipitation greatly improves 4-methylumbelliferone-based diagnostic assays for lysosomal storage diseases in dried blood spots

(2010) L.F. Oemardien et al.   MOLECULAR GENETICS AND METABOLISM

Digital Microfluidics: A Future Technology in the Newborn Screening Laboratory?

(2010) David S. Millington et al.   SEMINARS IN PERINATOLOGY

Pompe Disease in Infants: Improving the Prognosis by Newborn Screening and Early Treatment

(2009) Y.-H. Chien et al.   PEDIATRICS

Adaptive Cooling of Integrated Circuits Using Digital Microfluidics

(2008) P.Y. Paik et al.   IEEE TRANSACTIONS ON VERY LARGE SCALE INTEGRATION (VLSI) SYSTEMS

All-terrain droplet actuation

(2008) Mohamed Abdelgawad et al.   LAB ON A CHIP

Development of a digital microfluidic platform for point of care testing

(2008) Ramakrishna Sista et al.   LAB ON A CHIP

Newborn screening

(2008) Bridget Wilcken et al.   PATHOLOGY

Early Detection of Pompe Disease by Newborn Screening Is Feasible: Results From the Taiwan Screening Program

(2008) Y.-H. Chien et al.   PEDIATRICS