MicroRNA-21 aggravates chronic obstructive pulmonary disease by promoting autophagy

PTEN/PI3k/AKT Regulates Macrophage Polarization in Emphysematous mice

(2017) J. Lu et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

MicroRNA-21 activation of ERK signaling via PTEN is involved in arsenite-induced autophagy in human hepatic L-02 cells

(2016) Xinlu Liu et al.   TOXICOLOGY LETTERS

Inhibition of mammalian S6 kinase by resveratrol suppresses autophagy

(2016) Sean M. Armour et al.   Aging-US

Decitabine enhances stem cell antigen-1 expression in cigarette smoke extract-induced emphysema in animal model

(2015) Zhi-Hui He et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Cinnamtannin D1 from Rhododendron formosanum Induces Autophagy via the Inhibition of Akt/mTOR and Activation of ERK1/2 in Non-Small-Cell Lung Carcinoma Cells

(2015) Tzong-Der Way et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Risk factors for and origins of COPD

(2015) Anthony L Byrne et al.   LANCET

Comparison between cigarette smoke-induced emphysema and cigarette smoke extract-induced emphysema

(2015) Zhi-Hui He et al.   Tobacco Induced Diseases

MicroRNA-21 and the clinical outcomes of various carcinomas: a systematic review and meta-analysis

(2014) Wenjia Wang et al.   BMC CANCER

Effects of microRNA-21 on the interleukin 12/signal transducer and activator of transcription 4 signaling pathway in asthmatic mice

(2014) Song-Quan Wu et al.   Central European Journal of Immunology

An increased ratio of serum miR-21 to miR-181a levels is associated with the early pathogenic process of chronic obstructive pulmonary disease in asymptomatic heavy smokers

(2014) Lihua Xie et al.   Molecular BioSystems

Autophagy: A Crucial Moderator of Redox Balance, Inflammation, and Apoptosis in Lung Disease

(2013) Kiichi Nakahira et al.   ANTIOXIDANTS & REDOX SIGNALING

The role of dendritic cells in the pathogenesis of cigarette smoke-induced emphysema in mice

(2013) Masoumeh E. Givi et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

C-Kit/c-Kit ligand interaction of bone marrow endothelial progenitor cells is influenced in a cigarette smoke extract-induced emphysema model

(2013) Shengdong He et al.   EXPERIMENTAL LUNG RESEARCH

Role of microRNAs in Lung Development and Pulmonary Diseases

(2013) Roberto Sessa et al.   Pulmonary Circulation

Guidelines for the use and interpretation of assays for monitoring autophagy

(2012) Daniel J. Klionsky et al.   Autophagy

NOS2 enhances KRAS-induced lung carcinogenesis, inflammation and microRNA-21 expression

(2012) Hirokazu Okayama et al.   INTERNATIONAL JOURNAL OF CANCER

SIRT1 protects against emphysema via FOXO3-mediated reduction of premature senescence in mice

(2012) Hongwei Yao et al.   JOURNAL OF CLINICAL INVESTIGATION

Silencing of MicroRNA-21 Confers Radio-Sensitivity through Inhibition of the PI3K/AKT Pathway and Enhancing Autophagy in Malignant Glioma Cell Lines

(2012) Ho-Shin Gwak et al.   PLoS One

Cell Therapy with Bone Marrow Mononuclear Cells in Elastase-Induced Pulmonary Emphysema

(2012) Nathalia Longhini-dos-Santos et al.   Stem Cell Reviews and Reports

Insufficient autophagy promotes bronchial epithelial cell senescence in chronic obstructive pulmonary disease

(2012) Satoko Fujii et al.   OncoImmunology

Genetically manipulated mouse models of lung disease: potential and pitfalls

(2011) Rebecca M. Baron et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Autophagy: Renovation of Cells and Tissues

(2011) Noboru Mizushima et al.   CELL

Serine 403 Phosphorylation of p62/SQSTM1 Regulates Selective Autophagic Clearance of Ubiquitinated Proteins

(2011) Gen Matsumoto et al.   MOLECULAR CELL

Cigarette smoke-induced autophagy is regulated by SIRT1–PARP-1-dependent mechanism: Implication in pathogenesis of COPD

(2010) Jae-woong Hwang et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

COPD as a Disease of Accelerated Lung Aging

(2009) Kazuhiro Ito et al.   CHEST

Novel dry powder formulation of ovalbumin for development of COPD-like animal model: Physicochemical characterization and biomarker profiling in rats

(2009) Shingen Misaka et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Endothelin-1 receptor antagonists prevent the development of pulmonary emphysema in rats

(2009) Y. Chen et al.   EUROPEAN RESPIRATORY JOURNAL

Egr-1 Regulates Autophagy in Cigarette Smoke-Induced Chronic Obstructive Pulmonary Disease

(2008) Zhi-Hua Chen et al.   PLoS One