Article
Oncology
Umberto Carbonara, Giuseppe Simone, Andrea Minervini, Chandru P. Sundaram, Alessandro Larcher, Jennifer Lee, Enrico Checcucci, Cristian Fiori, Devin Patel, Margaret Meagher, Fabio Crocerossa, Alessandro Veccia, Lance J. Hampton, Pasquale Ditonno, Michele Battaglia, Aldo Brassetti, Alfredo Bove, Andrea Mari, Riccardo Campi, Marco Carini, Jay Sulek, Francesco Montorsi, Umberto Capitanio, Daniel Eun, Francesco Porpiglia, Ithaar Derweesh, Riccardo Autorino
Summary: The study showed that robotic partial nephrectomy for completely endophytic renal tumors can be performed with acceptable outcomes in centers with significant robotic expertise. Achieving the trifecta (negative margin, no postoperative complications, and 90% estimated glomerular filtration rate recovery) was significantly associated with clinical tumor size.
Article
Surgery
Makoto Toguchi, Tsunenori Kondo, Kazuhiko Yoshida, Kazunari Tanabe, Toshio Takagi
Summary: The generation of the surgeon may impact the perioperative outcomes of robot-assisted partial nephrectomy (RAPN). Patients operated by second-generation surgeons showed better surgical outcomes, especially during the early experience period.
Article
Oncology
Shohei Kawaguchi, Kouji Izumi, Renato Naito, Suguru Kadomoto, Hiroaki Iwamoto, Hiroshi Yaegashi, Takahiro Nohara, Kazuyoshi Shigehara, Kotaro Yoshida, Yoshifumi Kadono, Atsushi Mizokami
Summary: Advances in diagnostic imaging have led to increased opportunities for treating small-diameter renal cell carcinomas in the elderly. This study compared the efficacy of RAPN and PCA in elderly patients with small-diameter renal cell carcinomas, finding that RAPN is a safe and effective treatment, while PCA is a safe alternative for high-risk patients.
Article
Urology & Nephrology
Kendrick Yim, Monish Aron, Koon H. Rha, Giuseppe Simone, Andrea Minervini, Ben Challacombe, Luigi Schips, Francesco Berardinelli, Giuseppe Quarto, Reza Mehrazin, Devin Patel, Sunil Patel, Ahmet Bindayi, Akbar N. Ashrafi, Mihir Desai, Ali Alqahtani, Michele Gallucci, Jay Sulek, Andrea Mari, Nicolo De Luyk, Uzoma Anele, Riccardo Autorino, Francesco Porpiglia, Chandru P. Sundaram, Inderbir S. Gill, Sisto Perdona, Ithaar H. Derweesh
Summary: This study retrospectively evaluated the use of robot-assisted partial nephrectomy in patients with stage 3a kidney cancer. The results showed that some patients achieved excellent treatment outcomes, but a proportion of patients also experienced complications.
EUROPEAN UROLOGY FOCUS
(2021)
Article
Urology & Nephrology
Kenji Zennami, Kiyoshi Takahara, Ryo Matsukiyo, Takuhisa Nukaya, Masashi Takenaka, Kosuke Fukaya, Manabu Ichino, Naohiko Fukami, Hitomi Sasaki, Mamoru Kusaka, Hiroshi Toyama, Makoto Sumitomo, Ryoichi Shiroki
Summary: Robot-assisted partial nephrectomy (RAPN) appears to be safe and feasible for cystic renal tumors, with perioperative, long-term functional, and oncologic outcomes comparable to solid tumors. RAPN can be a safe and effective surgical option for patients with cystic renal tumors.
JOURNAL OF ENDOUROLOGY
(2021)
Article
Surgery
Takafumi Yagisawa, Toshio Takagi, Kazuhiko Yoshida, Keisuke Hata, Junpei Iizuka, Yasuto Muromiya, Tsunenori Kondo, Kazunari Tanabe
Summary: The study compared the surgical outcomes of RAPN between patients with cRCC and sRCC, finding that most surgical indicators did not show significant differences between the two groups. The results suggest the feasibility of RAPN for cRCC treatment.
JOURNAL OF ROBOTIC SURGERY
(2022)
Article
Oncology
Aldo Brassetti, Giovanni E. Cacciamani, Andrea Mari, Juan D. Garisto, Riccardo Bertolo, Chandru P. Sundaram, Ithaar Derweesh, Ahmet Bindayi, Prokar Dasgupta, James Porter, Alexander Mottrie, Luigi Schips, Koon Ho Rah, David Y. T. Chen, Chao Zhang, Kenneth Jacobsohn, Umberto Anceschi, Alfredo M. Bove, Manuela Costantini, Mariaconsiglia Ferriero, Riccardo Mastroianni, Leonardo Misuraca, Gabriele Tuderti, Alexander Kutikov, Wesley M. White, Stephen T. Ryan, Francesco Porpiglia, Jihad Kaouk, Andrea Minervini, Inderbir Gill, Riccardo Autorino, Giuseppe Simone
Summary: Robot-assisted partial nephrectomy is a viable option for treating tumors larger than 7 cm, but the risk of postoperative renal function deterioration should be considered. Off-clamp robotic partial nephrectomy has shorter operation times and may improve perioperative outcomes.
Article
Medicine, General & Internal
Kiyoshi Takahara, Mamoru Kusaka, Takuhisa Nukaya, Masashi Takenaka, Kenji Zennami, Manabu Ichino, Hitomi Sasaki, Makoto Sumitomo, Ryoichi Shiroki
Summary: This study retrospectively analyzed the risks and benefits of selective clamping in robot-assisted partial nephrectomy (RAPN). The results showed no significant differences in surgical time, warm ischemia time, or incidence rates of complications between the two groups. However, the estimated blood loss was significantly higher in the selective clamping group. Additionally, there were no significant intergroup differences in the postoperative preservation ratio of estimated glomerular filtration rate (eGFR) at 6 and 12 months of follow-up.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Urology & Nephrology
Umberto Carbonara, Giuseppe Simone, Umberto Capitanio, Andrea Minervini, Cristian Fiori, Alessandro Larcher, Enrico Checcucci, Daniele Amparore, Fabio Crocerossa, Alessandro Veccia, Samuel Weprin, Pasquale Ditonno, Aldo Brassetti, Alfredo Bove, Andrea Mari, Antonio Andrea Grosso, Marco Carini, Francesco Montorsi, Lance J. Hampton, Michele Gallucci, Francesco Porpiglia, Riccardo Autorino
Summary: A study on 85 patients who underwent RAPN showed excellent 7-year oncologic and functional outcomes, comparable to those achieved in historical series of open and laparoscopic surgery.
MINERVA UROLOGY AND NEPHROLOGY
(2021)
Article
Urology & Nephrology
Dane E. Klett, Matvey Tsivian, Vignesh T. Packiam, Christine M. Lohse, Mohamed E. Ahmed, Theodora A. Potretzke, Ajay Gopalakrishna, Stephen A. Boorjian, R. Houston Thompson, Bradley C. Leibovich, Aaron M. Potretzke
Summary: Partial nephrectomy appears to be a relatively safe and potentially effective treatment option for cT2 renal masses, offering better preservation of renal function compared to radical nephrectomy. These findings support the ongoing use of partial nephrectomy for renal masses larger than 7 cm in properly selected patients.
INTERNATIONAL JOURNAL OF UROLOGY
(2021)
Article
Oncology
Hugo Otaola-Arca, Alfred Krebs, Hugo Bermudez, Raul Lyng, Marcelo Orvieto, Alberto Bustamante, Conrado Stein, Andres Labra, Marcela Schultz, Mario Fernandez
Summary: Robot-assisted partial nephrectomy (RAPN) for renal cell carcinoma (RCC) has been shown to result in excellent long-term survival and preserved renal function in most patients. The incidence of local and distant relapse is low in this large cohort.
ANNALS OF SURGICAL ONCOLOGY
(2022)
Article
Urology & Nephrology
Hidekazu Tachibana, Kenji Omae, Hiroki Ishihara, Hironori Fukuda, Kazuhiko Yoshida, Junpei Iizuka, Kazunari Tanabe, Tsunenori Kondo, Toshio Takagi
Summary: The study validated a new simple equation that accurately predicts the glomerular filtration rate after radical and robot-assisted laparoscopic partial nephrectomies in Japanese patients. This model helps physicians in choosing surgical treatments for renal tumors in daily clinical practice.
JOURNAL OF ENDOUROLOGY
(2022)
Article
Urology & Nephrology
Gopal Sharma, Milap Shah, Puneet Ahluwalia, Prokar Dasgupta, Benjamin J. Challacombe, Mahendra Bhandari, Rajesh Ahlawat, Sudhir Rawal, Nicolo M. Buffi, Ananthakrishanan Sivaraman, James R. Porter, Craig Rogers, Alexandre Mottrie, Ronney Abaza, Khoon Ho Rha, Daniel Moon, Thyavihally B. Yuvaraja, Dipen J. Parekh, Umberto Capitanio, Kris K. Maes, Francesco Porpiglia, Levent Turkeri, Gagan Gautam
Summary: This study compared perioperative outcomes of robot-assisted partial nephrectomy in patients aged >= 70 years to those age < 70 years. The results showed that the procedure had comparable trifecta outcomes and acceptable perioperative morbidity in selected elderly patients.
WORLD JOURNAL OF UROLOGY
(2022)
Article
Andrology
Xiaozhi Zhao, Qun Lu, Changwei Ji, Guangxiang Liu, Xuefeng Qiu, Shiwei Zhang, Xiaogong Li, Gutian Zhang, Hongqian Guo
Summary: The study found that MRASE was superior to RAPN in achieving Trifecta for treating T1b renal tumors. In addition, MRASE showed better outcomes with shorter operative time, shorter warm ischemic time, and less need for tumor bed suturing compared to RAPN.
TRANSLATIONAL ANDROLOGY AND UROLOGY
(2021)
Article
Urology & Nephrology
Jo-Lynn S. Tan, Niranjan Sathianathen, Marcus Cumberbatch, Prokar Dasgupta, Alexandre Mottrie, Ronney Abaza, Koon Ho Rha, Thyavihally B. Yuvaraja, Dipen J. Parekh, Umberto Capitanio, Rajesh Ahlawat, Sudhir Rawal, Nicolo M. Buffi, Ananthakrishnan Sivaraman, Kris K. Maes, Gagan Gautham, Francesco Porpiglia, Levent Turkeri, Mahendra Bhandari, Benjamin Challacombe, James Roscoe Porter, Craig R. Rogers, Daniel A. Moon
Summary: The study compared peri-operative outcomes of patients undergoing robot-assisted partial nephrectomy for imperative vs elective indications. No significant differences were found in ischaemia time, operating time, estimated blood loss, rate of blood transfusions, or Clavien-Dindo complications between the two groups. However, a greater decrease in postoperative estimated glomerular filtration rate was observed in the imperative indication group.
Article
Urology & Nephrology
Francesco Del Giudice, David D'Andrea, Benjamin Pradere, Florian Berndl, Maximilian Pallauf, Rocco Simone Flammia, Dominik Philipp, Marco Moschini, Andrea Mari, Simone Albisinni, Wojciech Krajewski, Ekaterina Laukhtina, Andrea Gallioli, Laura S. Mertens, Gautier Marcq, Alessia Cimadamore, Luca Afferi, Paolo Gontero, Shahrokh F. Shariat, Benjamin Chung, Francesco Soria
Summary: This study found that in patients with non-muscle-invasive bladder cancer, the experience of surgeons was inversely associated with the presence of detrusor muscle in the specimen when the perioperative surgical checklist was adequately implemented. However, the experience of surgeons was directly linked to a higher probability of persistent disease during re-transurethral resection of bladder tumor. No differences were noted in 5-year recurrence-free survival based on surgical experience.
Article
Oncology
Antonio Cicione, Giuseppe Simone, Riccardo Lombardo, Antonio Franco, Antonio Nacchia, Nicola Ghezzo, Filippo Zammitti, Alessio Guidotti, Giacomo Gallo, Emilio Molinaro, Costantino Leonardo, Michele Gallucci, Siamak Daneshmand, Gus Miranda, Mihir M. Desai, Inderbir Gill, Hassan Abol-Enein, Andrea Tubaro, Cosimo De Nunzio
Summary: This study evaluated data from 2395 patients with primitive or progression to muscle invasive bladder cancer (MIBC) who underwent radical cystectomy and lymph nodes dissection, and developed a quick nomogram to predict death from cancer and relapse. The nomogram showed high accuracy in predicting both outcomes and can improve communication with patients.
CLINICAL GENITOURINARY CANCER
(2023)
Article
Oncology
Francesco Gentile, Evelina La Civita, Bartolomeo Della Ventura, Matteo Ferro, Dario Bruzzese, Felice Crocetto, Pierre Tennstedt, Thomas Steuber, Raffaele Velotta, Daniela Terracciano
Summary: The widespread use of PSA for prostate cancer diagnosis has led to high rates of overdiagnosis and overtreatment. A combination of the Prostate Health Index (PHI) and Proclarix tests can improve risk stratification of PCa patients at initial diagnosis. An artificial neural network model combining kallikrein markers in PHI and cancer-related markers in Proclarix showed increased accuracy in identifying aggressive PCa at initial diagnosis.
Review
Oncology
Francesco Del Giudice, Vincenzo Asero, Eugenio Bologna, Carlo Maria Scornajenghi, Dalila Carino, Virginia Dolci, Pietro Viscuso, Stefano Salciccia, Alessandro Sciarra, David D'Andrea, Benjamin Pradere, Marco Moschini, Andrea Mari, Simone Albisinni, Wojciech Krajewski, Tomasz Szydelko, Bartosz Malkiewicz, Lukasz Nowak, Ekaterina Laukhtina, Andrea Gallioli, Laura S. Mertens, Gautier Marcq, Alessia Cimadamore, Luca Afferi, Francesco Soria, Keiichiro Mori, Karl Heinrich Tully, Renate Pichler, Matteo Ferro, Octavian Sabin Tataru, Riccardo Autorino, Simone Crivellaro, Felice Crocetto, Gian Maria Busetto, Satvir Basran, Michael L. Eisenberg, Benjamin Inbeh Chung, Ettore De Berardinis
Summary: In this systematic review and meta-analysis, the cumulative bladder cancer (BC) recurrence rates and efficacy profile of different Bacillus of Calmette-Guerin (BCG) strains were compared. The study found that BCG Tokyo 172 had the lowest recurrence rate among studies with <= 3-year recurrence-free survival (RFS). No significant difference was observed among strains in >3-year RFS outcomes. The genetically different BCG strains RIVM, Tice, and Tokyo 172 showed some potential enhanced benefits.
Article
Urology & Nephrology
Julien Sarkis, Romain Diamand, Fouad Aoun, Gregoire Assenmacher, Christophe Assenmacher, Gregory Verhoest, Serge Holz, Michel Naudin, Guillaume Ploussard, Andrea Mari, Andrea Minervini, Andrea Tay, Rami Issa, Mathieu Roumiguie, Anne S. Bajeot, Giuseppe Simone, Umberto Anceschi, Paolo Umari, Ashwin Sridhar, John Kelly, Kees Hendricksen, Sarah Einerhand, Laura S. Mertens, Rafael Sanchez-Salas, Anna Colomer, Thierry Quackels, Alexandre Peltier, Francesco Montorsi, Alberto Briganti, Benjamin Pradere, Marco Moschini, Thierry Roumeguere, Simone Albisinni, EAU YAU, Urothelial Carcinoma Working Grp
Summary: A multicenter study found that intraoperative blood transfusions (iBT) during robot-assisted radical cystectomy (RARC) increased the risk of recurrence in urothelial carcinoma of the bladder (UCB), but showed no significant association with cancer-specific survival (CSS) and overall survival (OS). Post-operative blood transfusions (pBT) were not associated with worse oncological prognosis.
MINERVA UROLOGY AND NEPHROLOGY
(2023)
Article
Urology & Nephrology
Francesco DEL Giudice, Wansuk Kim, Shufeng LI, Ettore DE Berardinis, Alessandro Sciarra, Stefano Salciccia, Matteo Ferro, Riccardo Autorino, Savio D. Pandolfo, Felice Crocetto, Antonio Galfano, Paolo Dell'oglio, Giovanni E. Cacciamani, Benjamin Pradere, Ekaterina Laukhtina, David D'andrea, Federico Belladelli, Wojciech Krajewski, Andrea Mari, Andrea Minervini, Andrea Gallioli, Daniele Amparore, Enrico Checcucci, Cristian Fiori, Francesco Porpiglia, Luca Morgantini, Simone Crivellaro, Benjamin I. Chung
Summary: This study aimed to understand the ultimate fate of incidental adrenal masses and found that in the US, surveillance is more common than surgical excision for adrenal incidentalomas. Surgery is mainly offered for functional or malignant disease and the choice of surgical approach varies by physician specialty. Minimally invasive surgery predicted lower rates of complications and shorter hospital stay.
MINERVA UROLOGY AND NEPHROLOGY
(2023)
Article
Urology & Nephrology
Markus von Deimling, Marc Furrer, Laura S. Mertens, Andrea Mari, Noor van Ginkel, Mara Bacchiani, Moritz Maas, Renate Pichler, Roger Li, Marco Moschini, Alberto Bianchi, Malte W. Vetterlein, Chiara Lonati, Felice Crocetto, Jacob Taylor, Karl H. Tully, Luca Afferi, Francesco Soria, Francesco del Giudice, Mattia Longoni, Ekaterina Laukhtina, Alessandro Antonelli, Michael Rink, Margit Fisch, Yair Lotan, Philippe E. Spiess, Peter C. Black, Bernhard Kiss, Benjamin Pradere, Shahrokh F. Shariat
Summary: In patients with clinically lymph node-positive bladder cancer, extended pelvic lymph node dissection did not improve recurrence-free survival or overall survival compared to standard pelvic lymph node dissection, regardless of induction chemotherapy.
Review
Oncology
Francesco Ditonno, Celeste Manfredi, Antonio Franco, Alessandro Veccia, Fabrizio Dal Moro, Cosimo De Nunzio, Marco De Sio, Alessandro Antonelli, Riccardo Autorino
Summary: This study evaluated the impact of peritoneal reconfiguration on lymphocele formation in patients undergoing RARP with PLND. The results showed that performing peritoneal flap surgery can reduce the likelihood of lymphocele formation, as well as the associated complications and severe postoperative adverse events.
PROSTATE CANCER AND PROSTATIC DISEASES
(2023)
Editorial Material
Oncology
Antonio Franco, Riccardo Autorino
PROSTATE CANCER AND PROSTATIC DISEASES
(2023)
Review
Oncology
Antonio Franco, Francesco Ditonno, Carol Feng, Celeste Manfredi, Morgan R. Sturgis, Mustafa Farooqi, Francesco Del Giudice, Christopher Coogan, Matteo Ferro, Chao Zhang, Zhenjie Wu, Bo Yang, Linhui Wang, Riccardo Autorino
Summary: Minimally invasive radical nephroureterectomy is an important treatment option for upper tract urothelial cancer, offering oncological radicality and less surgical morbidity. Long-term outcomes suggest that it is safe and effective.
Article
Health Care Sciences & Services
Francesco Prata, Gianluigi Raso, Alberto Ragusa, Andrea Iannuzzi, Francesco Tedesco, Loris Cacciatore, Angelo Civitella, Piergiorgio Tuzzolo, Giuseppe D'Addurno, Pasquale Calle, Salvatore Basile, Marco Fantozzi, Matteo Pira, Salvatore Mario Prata, Umberto Anceschi, Giuseppe Simone, Roberto Mario Scarpa, Rocco Papalia
Summary: In this study, we performed off-clamp robot-assisted partial nephrectomy (RAPN) using the HugoTM RAS System. A simplified three-arm configuration was used for trocar placement and docking, resulting in feasible and safe practice with non-inferior perioperative outcomes.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Biology
Alberto Ragusa, Aldo Brassetti, Francesco Prata, Andrea Iannuzzi, Pasquale Calle, Francesco Tedesco, Loris Cacciatore, Francesco Esperto, Giuseppe Simone, Roberto Mario Scarpa, Rocco Papalia
Summary: Efforts have been made to predict urinary continence recovery after radical prostatectomy. This study investigated the impact of surgical urethral length preservation on urinary continence after laparoscopic-assisted radical prostatectomy. The results showed that surgical urethral length preservation and intraoperative blood loss of less than 250 mL were associated with urinary continence recovery.
Meeting Abstract
Urology & Nephrology
Sohail Dhanji, Franklin Liu, Kevin Hakimi, Hooman Djaladat, Firas Abdollah, Mark L. Gonzalgo, Linhui Wang, Matteo Ferro, Courtney Yong, Jacob Taylor, Savio D. Pandolfo, Francesco Porpiglia, Enrico Checcucci, Benjamin M. Eilender, Daniel D. Eun, Spencer H. Bell, Erika Wood, Alireza Ghoreifi, Matthew Davis, Alex Stephens, Gabriele Tuderti, Dinno F. Mendiola, Marco Tozzi, Riccardo Autorino, Chandru P. Sundaram, Reza Mehrazin, Vitaly Margulis, Giuseppe Simone, Zhenjie Wu, Ithaar Derweesh
JOURNAL OF UROLOGY
(2023)
Review
Urology & Nephrology
Morgan Salkowski, Enrico Checcucci, Alexander K. Chow, Craig C. Rogers, Firas Adbollah, Evangelos Liatsikos, Prokar Dasgupta, Gustavo C. Guimaraes, Jens Rassweiler, Alexander Mottrie, Alberto Breda, Simone Crivellaro, Jihad Kaouk, Francesco Porpiglia, Riccardo Autorino
Summary: The da Vinci robotic platform has dominated the field of robotic surgery for the past 20 years. However, in the past decade, numerous novel multiport robotic surgical systems have been developed and introduced into clinical practice. This review describes the designs, uses, and clinical outcomes of these new surgical robotic systems in urologic surgery. It focuses on the Senhance robotic system, the CMR-Versius robotic system, and the Hugo RAS, while also discussing lesser-known systems such as Avatera, Hintori, and Dexter. The notable features of each system are compared, with a particular emphasis on how they differ from the da Vinci robotic system.
THERAPEUTIC ADVANCES IN UROLOGY
(2023)
Article
Rehabilitation
April N. Herrity, Camilo Castillo, Roman V. Isakov, Uzoma A. Anele, Dengzhi Wang, Maxwell Boakye, Beatrice Ugiliweneza
Summary: Urinary tract infections (UTIs) following spinal cord injury (SCI) are common and result in increased health care utilization costs. This study characterized the risk factors and costs associated with UTIs in individuals with SCI. The results showed that younger age, female sex, thoracic level of injury, noncommercial insurance, and comorbidities were associated with increased odds of UTIs. UTIs were also associated with higher rates and costs of hospital admission, outpatient services, and prescription refills.
TOPICS IN SPINAL CORD INJURY REHABILITATION
(2023)