Review
Oncology
Rongrong Fan, Lili Wang, Xiaofan Bu, Wenxiu Wang, Jing Zhu
Summary: This scoping review examined the unmet supportive care needs among breast cancer survivors (BCSs). The study found that BCSs have a large number of unmet needs in terms of fear of cancer recurrence, daily activity, sexual/intimacy, psychology, and information.
Review
Oncology
Amy O'Dea, Craig Gedye, Belinda Jago, Catherine Paterson
Summary: People affected by kidney cancer have diverse unmet supportive care needs, with a strong focus on psychological and physical needs. Further research is needed to understand how clinical and demographic variables may influence these needs. This review serves as a starting point for future work to address the complex unmet supportive care needs of individuals affected by kidney cancer.
JOURNAL OF CANCER SURVIVORSHIP
(2022)
Review
Nursing
Sangeetha Thomas, Nicholas P. P. Ryan, Linda K. K. Byrne, Christel Hendrieckx, Victoria White
Summary: This study systematically reviewed the unmet supportive care needs of families with children with chronic health conditions and summarized the assessment tools used. The findings showed that families of children with cancer had the most prominent needs, and the unmet needs were mainly related to information and healthcare support. The study also revealed considerable variation in need assessments across different conditions, which limited comparisons between studies.
JOURNAL OF CLINICAL NURSING
(2023)
Article
Medicine, General & Internal
Frank J. Penedo, Akina Natori, Sara E. Fleszar-Pavlovic, Vandana D. Sookdeo, Jessica MacIntyre, Heidy Medina, Patricia I. Moreno, Tracy E. Crane, Craig Moskowitz, Carmen L. Calfa, Matthew Schlumbrecht
Summary: Unmet supportive care needs among ambulatory oncology patients are associated with worse clinical outcomes. Patients from racial and ethnic minority groups and those with greater emotional or physical burden are more likely to have unmet needs. Addressing unmet supportive care needs is crucial for improving clinical outcomes.
Article
Oncology
Minxing Chen, Ruijia Li, Yujie Chen, Gang Ding, Jie Song, Xiaojing Hu, Chunlin Jin
Summary: This study aims to identify the unmet needs of cancer survivors and explores the relationship between socio-demographic factors and unmet needs for supportive care. The findings show that information needs are the most common unmet need among cancer survivors, and time since diagnosis is associated with unmet supportive care needs. These findings highlight the gap between actual health services and patients' unmet need and provide a basis for a patient-centered supportive care system.
FRONTIERS IN ONCOLOGY
(2022)
Reprint
Oncology
Eline de Heus, Jan Maarten van der Zwan, Olga Husson, Anne-Roos Frissen, Carla M. L. van Herpen, Matthias A. W. Merkx, Saskia F. A. Duijts
Summary: Patients with rare cancers often report unmet supportive care needs in healthcare system and information domain (up to 95%), psychological domain (up to 93%) and physical and daily living domain (up to 80%), mainly in the posttreatment phase. The most frequently identified predictors were higher anxiety, younger age and higher neuroticism.
EUROPEAN JOURNAL OF CANCER CARE
(2021)
Review
Oncology
Nicolas H. Hart, Fiona Crawford-Williams, Megan Crichton, Jasmine Yee, Thomas J. Smith, Bogda Koczwara, Margaret I. Fitch, Gregory B. Crawford, Sandip Mukhopadhyay, Jane Mahony, Chan Cheah, James Townsend, Olivia Cook, Meera R. Agar, Raymond J. Chan
Summary: This review examined the prevalence of unmet supportive care needs in adults with advanced cancers and their caregivers. It found that financial, health system and information, psychological, and physical and daily living domains were the most prominent areas of unmet needs for patients, while psychological, patient care and support domains were the highest for caregivers. Distress, depression, and anxiety were associated with higher unmet needs in all domains.
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
(2022)
Article
Oncology
Yolanda Andreu, Paula Martinez, Ana Soto-Rubio, Silvia Fernandez, Carles Bosch, Andres Cervantes
Summary: This study aimed to determine the prevalence of distress and unmet supportive care needs in post-treatment colorectal cancer (CRC) survivors. Findings showed that one in five CRC survivors had clinical distress and 86% expressed at least one unmet need. The risk factors associated with this included lower socioeconomic status, younger age, and a primary treatment that includes more than surgery.
SUPPORTIVE CARE IN CANCER
(2022)
Review
Oncology
R. Doyle, P. Craft, M. Turner, C. Paterson
Summary: This study aimed to identify the experiences of unmet supportive care needs among individuals affected by testicular cancer. Out of 72 papers, 36 studies were included, which found that psychological needs were the most frequent, followed by physical needs and interpersonal/intimacy needs. The age of the individual was found to influence the frequency and distress of these needs.
JOURNAL OF CANCER SURVIVORSHIP
(2022)
Article
Oncology
Masako Okamura, Maiko Fujimori, Ayako Sato, Yosuke Uchitomi
Summary: The study found that over 70% of young adult cancer patients have unmet supportive care needs, with psychological needs being the most prominent. Factors associated with psychological needs include perceived poorer physical health, experience of changes in work/school after a cancer diagnosis, and poor social support. These results suggest potential opportunities for intervention in addressing psychological needs.
Article
Multidisciplinary Sciences
Nik Ruzyanei Nik Jaafar, Nur Amirah Hamdan, Norhaliza Abd Hamid, Rama Krsna Rajandram, Raynuha Mahadevan, Hazli Zakaria, Mohd Razif Mohamad Yunus, Mohammad Farris Iman Leong Bin Abdullah
Summary: This study investigated the level of posttraumatic growth (PTG) among head and neck cancer patients within the first year of diagnosis, as well as the association between unmet supportive care needs and fear of cancer progression with PTG. The results showed that higher levels of unmet needs and fear of cancer progression predicted lower PTG in these patients.
Review
Nursing
Ioanna Tsatsou, Theocharis Konstantinidis, Ioannis Kalemikerakis, Theodoula Adamakidou, Eugenia Vlachou, Ourania Govina
Summary: This review investigated the unmet supportive care needs of patients with hematological malignancies during and after active treatment. Various needs were identified, such as informational, emotional, physical, daily living/practical, and family life/relational needs, with factors like type of malignancy, age, gender, and quality of life affecting their intensity and frequency. The heterogeneity of studies makes generalization of results difficult.
ASIA-PACIFIC JOURNAL OF ONCOLOGY NURSING
(2021)
Review
Oncology
Olivia Bellas, Emma Kemp, Laura Edney, Candice Oster, Jackie Roseleur
Summary: This study aimed to describe the impacts of unmet supportive care needs on cancer survivors in Australia. The findings identified the negative impacts of unmet informational, physical, practical, emotional, and psychological needs on survivors.
EUROPEAN JOURNAL OF CANCER CARE
(2022)
Article
Health Care Sciences & Services
Junhee Park, Wonyoung Jung, Genehee Lee, Danbee Kang, Young Mog Shim, Hong Kwan Kim, Ansuk Jeong, Juhee Cho, Dong Wook Shin
Summary: The aim of this study was to identify the prevalence and predictors of unmet needs of NSCLC patients undergoing surgical resection in Seoul, South Korea. A total of 949 patients completed survey questionnaires and the results showed that 91.8% of participants reported one or more unmet need. The highest domains of unmet needs were existential survivorship, comprehensive cancer care, and information. High fear of cancer recurrence and poor emotional function were associated with unmet needs.
Review
Oncology
Verena Shuwen Wu, Allan Ben Smith, Afaf Girgis
Summary: This systematic review aims to identify the unmet supportive care needs of immigrant and native Chinese cancer patients and caregivers. The most prevalent area of unmet needs was health system and information, with patients desiring one member of the hospital to talk to about all aspects of their care and caregivers seeking information about the patient's prognosis and likely outcome.
EUROPEAN JOURNAL OF CANCER CARE
(2022)
Article
Oncology
Maria S. Lindgren, Erik Hansen, Nessn Azawi, Anna M. Nielsen, Lars Dyrskjot, Jorgen B. Jensen
Summary: This study aimed to assess the long-term outcomes of chemoresection with mitomycin for recurrent nonmuscle invasive bladder cancer. The results showed that chemoresection significantly reduced the number of patients requiring a procedure compared to standard surgical treatment. Short-term intensive chemoresection is an effective treatment strategy for recurrent NMIBC.
JOURNAL OF CLINICAL ONCOLOGY
(2023)
Review
Nursing
Amanda L. McKie, Murray Turner, Catherine Paterson
Summary: This meta-aggregation study has identified a range of unmet supportive care needs in people with kidney failure receiving haemodialysis. Living with kidney failure and undergoing haemodialysis impacts a person's sense of self and introduces practical and complex needs that are not being addressed in existing services. This review has important implications for clinical practice and future research directions.
JOURNAL OF RENAL CARE
(2023)
Letter
Urology & Nephrology
Maria S. Lindgren, Jorgen B. Jensen
Article
Surgery
Hayder Alhusseinawi, Rikke Haase, Sten Rasmussen, Jorgen B. Jensen, Pernille S. Kingo
Summary: This study validated a modified version of the 5-point subjective surgical rating scale (SRS) for evaluating the surgical workspace during robot-assisted radical nephrectomy (RARN). The results showed moderate inter-rater reliability and good to excellent intra-rater reliability.
INTERNATIONAL JOURNAL OF MEDICAL ROBOTICS AND COMPUTER ASSISTED SURGERY
(2023)
Article
Oncology
Emil Christensen, Iver Nordentoft, Karin Birkenkamp-Demtroder, Sara K. Elbaek, Sia Lindskrog, Ann Taber, Tine G. Andreasen, Trine Strandgaard, Michael Knudsen, Philippe Lamy, Mads Agerbaek, Jorgen B. Jensen, Lars Dyrskjot
Summary: The purpose of this study was to assess the use of plasma and urine DNA response in patients with muscle-invasive bladder cancer. Whole-exome sequencing was performed on tumor and germline DNA samples from 92 patients who received neoadjuvant chemotherapy followed by radical cystectomy. A custom NGS-panel was designed to track mutated tumor DNA in plasma and urine samples. The results showed that tumor DNA was detected in urine supernatants, urine pellets, and plasma samples.
CLINICAL CANCER RESEARCH
(2023)
Article
Medical Laboratory Technology
Maibritt Norgaard, Marianne T. Bjerre, Jacob Fredsoe, Soren Vang, Jorgen B. Jensen, Bram De Laere, Henrik Groenberg, Michael Borre, Johan Lindberg, Karina D. Sorensen
Summary: The clinical utility of low-pass whole-genome sequencing (LPWGS) of circulating tumor DNA (ctDNA) for prognostication in metastatic castration-resistant prostate cancer (mCRPC) was examined. The study found that high ctDNA% and high copy number alteration (CNA) burden at baseline were associated with poor treatment response, progression-free survival (PFS), and overall survival (OS). These findings were confirmed in an independent cohort.
CLINICAL CHEMISTRY
(2023)
Article
Nursing
Gabriella Michl, Catherine Paterson, Kasia Bail
Summary: This study aims to understand how nurses discuss documentation audit in relation to their professional role. The research findings indicate that nurses have concerns and reflections about the process of documentation audit and raise questions about its effectiveness. The study suggests that documentation audit has unintended negative consequences on patients, nurses, and workflows.
JOURNAL OF ADVANCED NURSING
(2023)
Article
Endocrinology & Metabolism
Iain Duncan, Nicholas Ingold, Elisa Martinez-Marroquin, Catherine Paterson
Summary: This study compared the diagnostic accuracy of Tc-PSMA SPECT/CT with mpMRI in the primary diagnosis of prostate cancer (PC) and found that Tc-PSMA SPECT/CT has a diagnostic performance similar to Ga-PSMA PET/CT and mpMRI. It may have advantages in terms of cost, sensitivity for primary lesion detection, and intraoperative localization of lymph nodes.
Article
Oncology
Kathryn Schubach, Theo Niyonsenga, Murray Turner, Catherine Paterson
Summary: This review included 21 publications reporting on 18 studies and found that sexual well-being is a significant concern for men and their partners with genitourinary cancers. However, there is limited knowledge about the experiences of using sexual well-being interventions in this population.
SUPPORTIVE CARE IN CANCER
(2023)
Article
Oncology
S. V. Lauridsen, B. T. Jensen, H. Tonnesen, S. O. Dalton, M. Rasmussen
Summary: Smoking cessation treatment is crucial for cancer survivors, but many continue smoking after diagnosis. This study compared the effectiveness of a 6-week intensive smoking cessation program among cancer survivors and smokers without cancer, as well as comparing successful quitting rates among disadvantaged and nondisadvantaged cancer survivors.
Article
Oncology
Mette Norgaard, Aurelie Mailhac, Karin Fagerlund, Torsten Strunz-McKendry, Mads Agerbaek, Jorgen Bjerggaard Jensen
Summary: This study described treatment patterns, survival, and healthcare utilisation/costs in Danish patients with locally advanced and metastatic urothelial bladder cancer (La/mUBC) in a routine clinical care setting. The study revealed that patients with La/mUBC have a poor prognosis, with only around half of the patients receiving systemic anti-cancer treatment, indicating an unmet need for novel treatments. The overall costs only increased slightly from first to third-line treatment.
Article
Oncology
Paul Vinu Salachan, Martin Rasmussen, Benedicte Parm Ulhoi, Jorgen Bjerggaard Jensen, Michael Borre, Karina Dalsgaard Sorensen
Summary: This study utilized spatial transcriptomics to explore the spatial gene expression heterogeneity within primary prostate tumors from patients with metastatic disease. It revealed impaired T cell activity due to nearby regulatory T cells in castration-resistant prostate cancer (CRPC), potentially mediating the aggressive disease phenotype. Additionally, significant immune-stroma cross-talk was identified in neuroendocrine prostate cancer (NEPC), characterized by ligand-receptor interactions between cancer-associated fibroblasts (CAFs) and M2 macrophages. This study highlights the importance of whole transcriptome profiling at spatial resolution for biomarker discovery and advancing our understanding of tumor biology.
INTERNATIONAL JOURNAL OF CANCER
(2023)
Review
Nursing
Catherine Paterson, A. Mckie, M. Turner, V. Kaak
Summary: Despite documented benefits, compliance rates with the World Health Organisation Patient Safety Checklist continue to pose risks to patient safety. This qualitative systematic review identified multiple key factors that influenced the uptake of the Surgical Safety Checklist in perioperative settings, including surgeon participation, hierarchical culture, complacency, and duplication of existing safety processes.
JOURNAL OF ADVANCED NURSING
(2023)
Review
Nursing
Tricia O'Connor, Jo Gibson, Joanne Lewis, Karen Strickland, Catherine Paterson
Summary: This study conducted a meta-aggregative systematic review to explore the application of the Cognitive Continuum Theory in qualitative nursing research and evaluate its visibility in the research process. The transferability of the theory was demonstrated, but evolution or critique was lacking. A gap in providing a patient-centric approach to decision-making was identified. A new Person-Centred Nursing Model of the Cognitive Continuum Theory was proposed for future research in clinical decision-making.
JOURNAL OF CLINICAL NURSING
(2023)
Review
Nursing
Laura Hants, Kasia Bail, Catherine Paterson
Summary: This study aims to explore how the nursing process has been incorporated into digital health systems and the benefits and challenges it poses to nurses' decision-making processes. The findings suggest that the assessment and planning components are well integrated into digital health systems, while interventions and outcome evaluation are lacking.
JOURNAL OF CLINICAL NURSING
(2023)
Article
Oncology
Diomidis Antoniadis, Alexander Giakoustidis, Vasileios Papadopoulos, Konstantinos N. Fountoulakis, Maggie Watson
Summary: The purpose of this study was to investigate the relationships between distress, psychological adjustment, and quality of life in patients with colon cancer. The results showed that quality of life was positively correlated with fighting spirit, cognitive avoidance, and fatalism, and negatively correlated with helplessness and hopelessness, and anxious preoccupation.
EUROPEAN JOURNAL OF ONCOLOGY NURSING
(2024)
Article
Oncology
Irem Gul, Ismail Toygar, Oznur Usta Yesilbalkan
Summary: This study investigated the support needs of carers of cancer patients and how the patient's age and cancer type affect their needs. The study found that carers of older adults and patients with hematological malignancies require more support in various aspects of caregiving.
EUROPEAN JOURNAL OF ONCOLOGY NURSING
(2024)