Article
Nutrition & Dietetics
Maria Ines Barreto Silva, Ana Paula Medeiros Menna Barreto, Karine Scanci da Silva Pontes, Mariana Silva da Costa, Kelli Trindade de Carvalho Rosina, Edison Souza, Rachel Bregman, Carla M. Prado, Marcia Regina Simas Torres Klein
Summary: This study investigated the accuracy and reproducibility of BIA and anthropometric predictive equations in estimating muscle mass in non-dialysis dependent patients with chronic kidney disease and kidney transplant recipients. The results showed that SMM-BIA by Janssen and ASM-BIA by Kyle had the best performance in assessing muscle mass, with high reproducibility when diagnosing low muscle mass using ASM/BMI in females and ASM/height(2) in males in both patient groups.
CLINICAL NUTRITION
(2021)
Article
Nutrition & Dietetics
Levent Gungor, Ethem Murat Arsava, Ayse Guler, Canan Togay Isikay, Ozlem Aykac, Hale Zeynep Batur Caglayan, Hasan Huseyin Kozak, Ustun Aydingoz, Mehmet Akif Topcuoglu
Summary: This study evaluated the changes in muscle mass and composition in acute ischemic stroke patients during their hospital stay and identified factors contributing to muscle loss.
CLINICAL NUTRITION
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Hugo C. van Heusden, Justin E. Swartz, Najiba Chargi, Pim A. de Jong, Mark C. P. M. van Baal, Inge Wegner, Remco de Bree
Summary: Measurement of skeletal muscle mass on chest CT can serve as a feasible alternative to abdominal CT, showing a strong correlation with measurements taken at the abdominal level. This may aid in diagnosing low skeletal muscle mass and could potentially be useful as a prognostic or triage tool in situations of mechanical ventilator shortage.
EUROPEAN JOURNAL OF RADIOLOGY
(2021)
Review
Cardiac & Cardiovascular Systems
Attila Feher, Lauren A. Baldassarre, Albert J. Sinusas
Summary: Anthracycline-induced cardiotoxicity is a common side effect of using these drugs. Cardiac computed tomography (CCT) is evolving rapidly and can provide detailed information on cardiac structure, coronary arteries, myocardial deformation, extracellular volume, and coronary vasoreactivity. There is also potential for molecular imaging with CCT.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Review
Radiology, Nuclear Medicine & Medical Imaging
Shanigarn Thiravit, Christina Brunnquell, Larry M. Cai, Mena Flemon, Achille Mileto
Summary: DECT has significant advantages in renal mass evaluation, helping to identify incidentally discovered masses and provide additional information. Virtual unenhanced and iodine density DECT images should be interpreted side-by-side to avoid misinterpretation.
EUROPEAN RADIOLOGY
(2021)
Article
Nutrition & Dietetics
Arabella Fischer, Anatol Hertwig, Ricarda Hahn, Martin Anwar, Timo Siebenrock, Maximilian Pesta, Konstantin Liebau, Isabel Timmermann, Jonas Brugger, Martin Posch, Helmut Ringl, Dietmar Tamandl, Michael Hiesmayr
Summary: This study aimed to investigate the feasibility of ultrasound in predicting skeletal muscle area. The results showed that one single ultrasound measuring point at the thigh, along with sex, height, and weight, can effectively predict CT L3 SMA, which is important for assessing muscle mass.
CLINICAL NUTRITION
(2022)
Article
Nutrition & Dietetics
Casper Simonsen, Thomas S. Kristensen, Anna Sundberg, Sabrina Wielsoe, Jan Christensen, Carsten P. Hansen, Stefan K. Burgdorf, Charlotte Suetta, Pieter de Heer, Lars B. Svendsen, Michael P. Achiam, Jesper F. Christensen
Summary: The prevalence of sarcopenia defined using DXA and CT varies substantially, and the agreement between the two modalities is poor.
CLINICAL NUTRITION
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Andreas Kammerlander, Asya Lyass, Taylor F. Mahoney, Jana Taron, Parastou Eslami, Michael T. Lu, Michelle T. Long, Ramachandran S. Vasan, Joseph M. Massaro, Udo Hoffmann
Summary: This study aimed to establish a standard for quantifying total abdominal muscle mass (TAM) on computed tomography (CT) and investigate its association with cardiovascular risk. TAM-Fraction was found to be significantly associated with cardiovascular risk factors and events.
EUROPEAN RADIOLOGY
(2022)
Article
Geriatrics & Gerontology
D. De Marco, S. Mamane, W. Choo, L. Mullie, X. Xue, M. Afilalo, J. Afilalo
Summary: This study provides reference values and age-related decline trends for CT muscle parameters at L4 in a healthy population, using an accessible web-based software, which is valuable for interpreting and applying these imaging biomarkers of sarcopenia in clinical care.
JOURNAL OF NUTRITION HEALTH & AGING
(2022)
Article
Medicine, General & Internal
Kazuki Ohashi, Toru Ishikawa, Asami Hoshii, Tamaki Hokari, Hirohito Noguchi, Mitsuyuki Suzuki, Hiroshi Hirosawa, Michitaka Imai, Yuta Mitobe, Toshiaki Yoshida
Summary: Using CT scans to measure total muscle area at the level of the third lumbar vertebra as the cut-off values for Skeletal Muscle Mass Index (SMI), with DXA as the reference method.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Geriatrics & Gerontology
Takafumi Mizuno, Yasumoto Matsui, Makiko Tomida, Yasuo Suzuki, Yukiko Nishita, Chikako Tange, Hiroshi Shimokata, Shiro Imagama, Rei Otsuka, Hidenori Arai
Summary: The study found that both quadriceps muscle cross-sectional area and computed tomography values decreased with age, while intermuscular adipose tissue area did not show a clear trend. There were sex-related differences and differences in the muscles contributing to knee extension strength between men and women. Quadriceps cross-sectional area and computed tomography values are useful for objectively assessing age-related and sex-related muscle deterioration and knee extension strength.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE
(2021)
Article
Geriatrics & Gerontology
Sung Woo Moon, Sang Hoon Lee, Ala Woo, Ah Young Leem, Su Hwan Lee, Kyung Soo Chung, Eun Young Kim, Ji Ye Jung, Young Ae Kang, Moo Suk Park, Young Sam Kim, Chang Oh Kim, Song Yee Kim
Summary: This study aimed to establish reference values for sarcopenia of thoracic skeletal muscles acquired from chest CT scans and analyze variables related to sarcopenia. The findings provide sex-specific standardized methods for quantifying thoracic muscle mass and assessing sarcopenia.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Lingling Tan, Guiyi Ji, Ting Bao, Hongbo Fu, Ling Yang, Ming Yang
Summary: The measurement of muscle mass and quality using chest CT images can aid in sarcopenia and myosteatosis research. This study found that muscle mass and quality indicators from CT images are valuable for diagnosing these conditions in healthy Chinese adults.
INSIGHTS INTO IMAGING
(2021)
Article
Physiology
Masatoshi Naruse, William A. Fountain, Alex Claiborne, W. Holmes Finch, Scott Trappe, Todd A. Trappe
Summary: This study shows that older individuals experience muscle atrophy and hypertrophy in a muscle-specific manner, with the quadriceps, hamstrings, psoas, and rectus abdominis atrophying while the lateral abdominals and paraspinals hypertrophying. These findings contribute to a better understanding of skeletal muscle aging and highlight the importance of studying muscle-specific changes in older adults.
JOURNAL OF APPLIED PHYSIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Farhad Pishgar, Mahsima Shabani, Thiago Quinaglia A. C. Silva, David A. Bluemke, Matthew Budoff, R. Graham Barr, Matthew A. Allison, Wendy S. Post, Joao A. C. Lima, Shadpour Demehri
Summary: In participants with COPD, higher intermuscular adipose tissue index was associated with greater risk of mortality, while higher subcutaneous adipose tissue index was associated with lower mortality risk, as demonstrated by chest CT soft-tissue markers analysis.
Article
Urology & Nephrology
Jessica Machado, Roberta Fontanive Miyahira, Monica Marques, Nathalia Moura-Nunes, Renata Rangel Guimaraes, Lilia Zago, Isabelle Santana, Maurilo Leite Junior, Carla Maria Avesani
Summary: This study developed two non-industrial food products for HD patients, one of which is a protein-enriched muffin with fine herbs. The protein-enriched muffins had higher protein content and lower carbohydrate content compared to the standard formulation and were well-accepted by patients.
JOURNAL OF NEPHROLOGY
(2021)
Review
Urology & Nephrology
Alice Sabatino, Lilian Cuppari, Peter Stenvinkel, Bengt Lindholm, Carla Maria Avesani
Summary: Sarcopenia, initially defined as muscle loss in elderly by Irwin Rosenberg in 1988, has now evolved to encompass not only muscle mass loss but also strength and physical performance decline in consensus papers. In CKD, sarcopenia is prevalent not just due to aging, but also accelerated protein breakdown from the disease and dialysis, associated with worse clinical outcomes.
JOURNAL OF NEPHROLOGY
(2021)
Article
Nutrition & Dietetics
Carla Maria Avesani, Alice Sabatino, Alessandro Guerra, Juliana Rodrigues, Juan Jesus Carrero, Giovanni Maria Rossi, Giacomo Garibotto, Peter Stenvinkel, Enrico Fiaccadori, Bengt Lindholm
Summary: This study evaluated the performance of GLIM in identifying malnutrition in MHD patients, and found that it had low agreement, sensitivity, and accuracy compared to 7p-SGA and MIS. The well-established 7p-SGA and MIS methods may be more useful in this clinical setting, considering the specific wasting characteristics in MHD.
JOURNAL OF RENAL NUTRITION
(2022)
Article
Nutrition & Dietetics
Lorena Cristina Curado Lopes, Maria Cristina Gonzalez, Carla Maria Avesani, Carla M. Prado, Maria do Rosario Gondim Peixoto, Joao Felipe Mota
Summary: The study evaluated the association of hand grip strength with body composition, functional capacity, muscle quality, and inflammatory markers in people receiving maintenance hemodialysis. Participants with low hand grip strength showed lower functional capacity and higher inflammation markers compared to those with adequate hand grip strength.
Article
Urology & Nephrology
Alice Sabatino, Giuseppe Regolisti, Giuseppe Benigno, Francesca Di Mario, Carla Maria Avesani, Enrico Fiaccadori
Summary: In this study, low skeletal muscle area was detected in hemodialysis patients using abdominal CT imaging with cut-offs derived from healthy subjects. Low skeletal muscle area assessed by CT was independently associated with all-cause mortality in end-stage kidney disease patients on hemodialysis.
JOURNAL OF NEPHROLOGY
(2022)
Article
Nutrition & Dietetics
Marvery P. Duarte, Heitor S. Ribeiro, Lucas S. Almeida, Victor M. Baiao, Antonio Inda-Filho, Carla Maria Avesani, Aparecido P. Ferreira, Ricardo M. Lima
Summary: SARC-F and SARC-CalF are associated with sarcopenia traits in patients undergoing hemodialysis. SARC-CalF seems to be more strongly associated with sarcopenia traits and present a higher sensitivity for probable sarcopenia than SARC-F, as it adds a direct measurement.
NUTRITION IN CLINICAL PRACTICE
(2022)
Editorial Material
Urology & Nephrology
Carla Maria Avesani, Alice Sabatino
JORNAL BRASILEIRO DE NEFROLOGIA
(2022)
Review
Nutrition & Dietetics
Giorgina Barbara Piccoli, Tommy Cederholm, Carla Maria Avesani, Stephan J. L. Bakker, Vincenzo Bellizzi, Cristina Cuerda, Adamasco Cupisti, Alice Sabatino, Stephane Schneider, Massimo Torreggiani, Denis Fouque, Juan Jesus Carrero, Rocco Barazzoni
Summary: Increased life expectancy presents significant challenges to healthcare systems globally, including the rise in chronic kidney disease (CKD) and malnutrition-protein-energy wasting (PEW) in older adults, leading to poor clinical outcomes. A critical review paper by ESPEN and ERN-ERA aims to summarize key concepts in preventing and treating CKD progression and impaired nutritional status, and provide guidance on defining optimal protein and energy intake in varying CKD severity. Careful assessment and individualized approach are necessary, considering malnutrition-PEW status, kidney function, and patient preferences. Greater awareness and research are needed to improve nutritional care for this growing patient subgroup.
CLINICAL NUTRITION
(2023)
Article
Nutrition & Dietetics
Andresa da Silva Couto, Maria Cristina Gonzalez, Renata Brum Martucci, Patricia Moreira Feijo, Viviane Dias Rodrigues, Nivaldo Barroso de Pinho, Nilian Carla Souza
Summary: This study aimed to evaluate the agreement, accuracy, sensitivity, specificity, and prognostic effect of the Global Leadership Initiative on Malnutrition (GLIM) in patients with colorectal cancer, compared with the Patient-Generated Subjective Global Assessment (PG-SGA). The GLIM showed fair sensitivity, good agreement, specificity, and diagnostic accuracy for detecting malnutrition, and was associated with short-term survival in patients with colorectal cancer.
JOURNAL OF PARENTERAL AND ENTERAL NUTRITION
(2023)
Letter
Nutrition & Dietetics
Alice Sabatino, Carla Avesani
CLINICAL NUTRITION
(2023)
Editorial Material
Nursing
Sintra Eyre, Jenny Stenberg, Ola Wallengren, David M. Keane, Carla Avesani, Ingvar Bosaeus, Naomi Clyne, Olof Heimburger, Ainhoa Indurain, Ann-Cathrine Johansson, Bengt Lindholm, Fernando Seoane, Mia Trondsen, SWEBIS network
JOURNAL OF RENAL CARE
(2023)
Correction
Urology & Nephrology
Carla Maria Avesani, Peter Stenvinkel, Alice Sabatino, Claudia D'Alessandro, Giorgina Barbara Piccoli
JOURNAL OF NEPHROLOGY
(2023)
Review
Urology & Nephrology
Fabiola Martin-del-Campo, Carla Maria Avesani, Peter Stenvinkel, Bengt Lindholm, Alfonso M. Cueto-Manzano, Laura Cortes-Sanabria
Summary: Protein-energy wasting (PEW) is common in patients with chronic kidney disease (CKD) and is associated with increased morbidity and mortality, and lower quality of life. Gut dysbiosis plays an important role in inflammation and uremic toxin retention, contributing to the development of PEW. Understanding the interactions between gut microbiota and the host may lead to the development of new strategies to improve nutrition and clinical outcomes in CKD patients.
JOURNAL OF NEPHROLOGY
(2023)
Review
Urology & Nephrology
Carla Maria Avesani, Aline Miroski de Abreu, Heitor S. Ribeiro, Torkel B. Brismar, Peter Stenvinkel, Alice Sabatino, Bengt Lindholm
Summary: Muscle fat infiltration (MFI), also known as myosteatosis, refers to the accumulation of lipids in the skeletal muscle. MFI is usually assessed using imaging methods like CT, MRI, and ultrasound, primarily in the legs, arms, and trunk muscle groups. MFI is considered a marker of muscle quality, where higher fat deposition in the muscle leads to decreased contraction power and force production per unit of muscle mass.
JOURNAL OF NEPHROLOGY
(2023)
Article
Urology & Nephrology
Marina Padial, Angeline Taylor, Alice Sabatino, Giorgina Barbara Piccoli, Carla Maria Avesani
Summary: Ultraprocessed food poses risks to kidney health due to its high content of salt, sugar, unhealthy fats, and additives. Understanding and addressing the importance of this issue requires integrating nutritional counseling and providing educational material to patients, caregivers, and healthcare providers.
JOURNAL OF NEPHROLOGY
(2023)