Review
Biochemistry & Molecular Biology
Austin Lu, Emma Ivantsova, Christopher J. Martyniuk
Summary: This study reviews the concentrations of acetochlor in aquatic ecosystems globally and its biological impacts on fish. Acetochlor exposure may cause morphological defects, developmental toxicity, endocrine and immune system disruption, cardiotoxicity, oxidative stress, and altered behavior in fish. Computational toxicology and molecular docking approaches were used to identify putative toxicity pathways, and potential targets for acetochlor disruption were revealed. However, the immunotoxicity and behavioral toxicity of acetochlor have not been fully investigated, and further research should focus on these mechanisms.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2023)
Article
Environmental Sciences
Hana Caloudova, Jana Blahova, Jan Mares, Lukas Richtera, Ales Franc, Michaela Garajova, Frantisek Tichy, Jiri Lenz, Jana Caloudova, Vladimira Enevova, Pavel Kopel, Barbora Havelkova, Pavla Lakdawala, Zdenka Svobodova
Summary: In this study, the subchronic effects of Magneli phase titanium suboxides (Magneli TiOx) were evaluated and compared with TiO2 particles. It was found that Magneli TiOx had fewer adverse effects on fish compared to TiO2, and exhibited good antioxidant stress resistance.
Article
Environmental Sciences
Monike Felipe Gomes, Vinicius de Carvalho Soares de Paula, Lucia Regina Rocha Martins, Juan Ramon Esquivel Garcia, Flavia Yoshie Yamamoto, Adriane Martins de Freitas
Summary: The study assessed the toxicity of triclosan, triclocarban, and their binary mixture on catfish embryos at environmentally relevant concentrations. The results showed potential toxicity of these chemicals even at low concentrations and short exposure periods.
Article
Environmental Sciences
Sathisaran Umamaheswari, Sheela Priyadarshinee, Monojit Bhattacharjee, Krishna Kadirvelu, Mathan Ramesh
Summary: The study shows that polystyrene microplastics induce various toxic effects in zebrafish, including disrupting the antioxidant defense system, causing histopathological lesions, and altering gene expression patterns.
Article
Environmental Sciences
Raquel S. F. Vieira, Carlos A. S. Venancio, Luis M. Felix
Summary: The study found concentration-dependent teratogenic effects of Azoxystrobin on zebrafish embryos, but low concentrations may induce oxidative stress response. The results suggest that Azoxystrobin may pose ecotoxicological risks to non-target species.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
Article
Environmental Sciences
Rosemarie de la Rosa, Sergio Vazquez, Phum Tachachartvanich, Sarah Daniels, Fenna Sille, Martyn T. Smith
Summary: A cell-based bioassay was developed to measure total glucocorticogenic activity of environmental chemicals and human serum. The assay is specific and sensitive, providing a useful tool for rapidly screening substances that may affect glucocorticoid signaling.
ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
(2021)
Review
Environmental Sciences
Ana Paula Da Silva, Elizete Rodrigues Morais, Elton Celton Oliveira, Nedia de Castilhos Ghisi
Summary: This meta-analysis study evaluates the toxic effects of 2,4-dichlorophenoxyacetic acid (2,4-D) on various animal species. The results indicate a significant increase in mortality rate for animals exposed to environmental concentrations of 2,4-D, with fish and birds being more susceptible. Larval and adult animals are more sensitive to 2,4-D, and immersion exposure has the greatest impact. Furthermore, commercial formulations have a higher mortality rate compared to analytical standards.
ENVIRONMENTAL POLLUTION
(2022)
Article
Environmental Sciences
Gabriele Magara, Antonia Concetta Elia, Ambrosius Josef Martin Dorr, Maria Cesarina Abete, Paola Brizio, Barbara Caldaroni, Marzia Righetti, Paolo Pastorino, Melissa Scoparo, Marino Prearo
Summary: The study observed stress responses in rainbow trout liver after receiving injections of tributyltin compounds, indicating different stress mechanisms caused by TBTC and TBTE. The findings suggest an ecotoxicological risk for freshwater ecosystems due to the weak induction of metal-trapping metallothioneins and changes in oxidative stress biomarkers in TBT-treated trout.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Fisheries
Sonnich Meier, Terje van der Meeren, Jon Egil Skjaeraasen, Raymond J. Bannister, Josef Daniel Rasinger, Orjan Karlsen
Summary: This study examines whether mature Atlantic cod caught at spawning grounds in Smola, Norway, have eaten salmon waste feed. The results show that 13% and 20% of sampled cod in 2018 and 2019 respectively had high concentrations of terrestrial fatty acids, indicating waste feed feeding. Cod feeding on waste feed had large, fatty livers and the terrestrial fatty acids were also transferred to the muscle and gonad lipids.
ICES JOURNAL OF MARINE SCIENCE
(2023)
Article
Medicine, Research & Experimental
Renner Philipe Rodrigues Carvalho, Fernanda Carolina Dias Ribeiro, Thaina Iasbik Lima, Luiz Otavio Guimaraes Ervilha, Elizabeth Lopes de Oliveira, Alessandra de Oliveira Faustino, Graziela Domingues de Almeida Lima, Mariana Machado-Neves
Summary: This study evaluated the effects of eugenol intake on liver morphology and physiology in rats. The results showed that low doses of eugenol had no significant effects, but high doses caused liver tissue damage and impaired liver functionality.
Article
Environmental Sciences
Tuhina Gayen, Anchal Tripathi, Usha Kumari, Swati Mittal, Ajay Kumar Mittal
Summary: This study aimed to investigate the impact of environmentally relevant concentrations of aspirin on the liver of Labeo rohita. The results showed that aspirin caused significant alterations in biochemical parameters, such as antioxidant enzyme activity and lipid peroxidation, as well as histopathological changes in the liver. These findings suggest that aspirin has toxic effects on fish and could be used as potential indicators of pharmaceutical toxicity in environmental biomonitoring.
Article
Biochemistry & Molecular Biology
Hamed Ghafarifarsani, Seyed Hossein Hoseinifar, Mahdieh Raeeszadeh, Seerengaraj Vijayaram, Md Fazle Rohani, Hien Van Doan, Yun-Zhang Sun
Summary: Recently, there has been significant attention towards the use of nano feed supplements to improve aquatic production and the environment. In this study, both chemically synthesized and green synthesized nanoparticles were characterized using various analytical techniques. The results showed that the green synthesized zinc oxide nanoparticles had a conical shape and a size range of 60 to 70 nm. Hematological and biochemical parameters in aquatic animals were evaluated after exposure to different doses of these nanoparticles. The findings suggest that higher doses of green synthesized zinc nanoparticles have less toxic effects and can act as suitable nutrient supplements in aquatic animals.
BIOLOGICAL TRACE ELEMENT RESEARCH
(2023)
Review
Agriculture, Dairy & Animal Science
Mohammed A. E. Naiel, Samar S. Negm, Shakira Ghazanfar, Mustafa Shukry, Sameh A. Abdelnour
Summary: The application of high-fat diet (HFD) in fish farming can promote growth and productivity, but excessive intake leads to undesirable effects on fish performance, such as impaired growth, reduced feed efficiency, liver dysfunction, weakened immune function and decreased economic revenue. Various approaches, such as dietary manipulation and feed additives, have been used to mitigate the adverse impacts of HFD and improve fish growth and productivity.
JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION
(2023)
Article
Environmental Sciences
Yan Wang, Yanjian Wan, Meiling Cao, Aizhen Wang, Gaga Mahai, Zhenyu He, Shunqing Xu, Wei Xia
Summary: This study investigated the exposure of pregnant women to herbicide 2,4-dichlorophenoxyacetic acid (2,4-D) in China and found significant positive associations between 2,4-D and oxidative stress biomarkers. These findings are important for verifying such associations and studying other potential adverse effects of 2,4-D exposure.
Article
Education, Scientific Disciplines
Opeyemi Ayanda, Ajayi Tolulope, Sonnie J. Oniye
Summary: The study found that glyphosate and paraquat, two herbicides commonly used in agricultural activities, can induce DNA damage and cell abnormalities in juvenile African Catfish. Paraquat was found to be more toxic and caused more severe DNA damage, as well as increased occurrence of abnormal cells in fish blood. This reflects the mutagenic potential of these herbicides in fish and the threat they pose to aquatic life in natural water bodies.
Article
Pharmacology & Pharmacy
Adilson Paulo Sinhorin, Jacqueline Kerkhoff, Evadro Luiz Dall'Oglio, Domingos de Jesus Rodrigues, Leonardo Gomes de Vasconcelos, Valeria Dornelles Gindri Sinhorin
Article
Chemistry, Medicinal
Naiele Sartori Patias, Valeria Dornelles Gindri Sinhorin, Fernando Rafael de Moura, Ana Paula Simoes da Cunha, Ritane Rose da Silva Lima, Thaniara Barbosa da Costa, Romeu Jose da Costa, Larissa Cavalheiro, Rogerio de Campos Bicudo, Adilson Paulo Sinhorin
Summary: This study identified the antioxidant properties of crude ethanolic extract and ethyl acetate fraction from Protium heptaphyllum. The presence of flavonoids in the extract and fraction may contribute to their antioxidant effects. Results showed that the ethyl acetate fraction was effective in reversing the effects of acetaminophen intoxication on liver and kidney tissues, and may also have hypoglycemic effects.
NATURAL PRODUCTS JOURNAL
(2021)
Article
Environmental Sciences
Wagner Bragante, Valeria Dornelles Gindri Sinhorin, Marina Mariko Sugui, Ana Paula Simoes da Cunha, Weslley Bressan dos Santos, Adilson Paulo Sinhorin
Summary: This study evaluated the biological effects of ingesting the pesticides cypermethrin and emamectin benzoate, as well as their mixtures, in female Swiss mice for 28 days. The results showed that the pesticide mixtures caused genotoxic damage and oxidative brain damage in the mice, potentially impacting their health and future offspring.
JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART B-PESTICIDES FOOD CONTAMINANTS AND AGRICULTURAL WASTES
(2022)
Article
Chemistry, Multidisciplinary
Sheila R. N. Pelissari, Valeria D. G. Sinhorin, Lindsey Castoldi, Leonardo G. de Vasconcelos, Domingos J. Rodrigues, Eloana B. S. Ribeiro, Jacqueline Kerkhoff, Adilson P. Sinhorin
Summary: This study investigated the chemical composition, immunomodulatory and antioxidant activities, as well as histopathological effects of methanolic extract from R. marina poison on mice tissues. The results showed that different doses and treatment periods had varying effects on cytokine production, tissue damage, and overall immune system modulation. The study highlights the biotechnological potential of the molecules found in the extract in improving antioxidant and immune system functions.
JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY
(2021)
Article
Medicine, General & Internal
Tatiane Cordeiro Luiz, Ana Paula Simoes da Cunha, Danilo Henrique Aguiar, Marina Mariko Sugui, Rogerio de Campos Bicudo, Adilson Paulo Sinhorin, Valeria Dornelles Gindri Sinhorin
Article
Medicine, General & Internal
Paloma Filomena Gouveia Rodrigues, Lucineia Reuse Albiero, Eduardo Figueredo Nery, Taiany Oliveira Kelly, Jeniffer Charlene Silva Dalazen, Debora Linsbinski Pereira, Adilson Paulo Sinhorin, Valeria Dornelles Gindri Sinhorin, Lindsey Castoldi
Article
Nursing
Diego Florencio Lima, Debora Linsbinski Pereira, Fabio Francoly Franciscon, Claudia dos Reis, Valfran da Silva Lima, Pacifica Pinheiro Cavalcanti