Article
Environmental Sciences
Qing Yang, Ping Deng, Dan Xing, Haoling Liu, Fang Shi, Lian Hu, Xi Zou, Hongyan Nie, Junli Zuo, Zimeng Zhuang, Meiqi Pan, Juan Chen, Guangyu Li
Summary: The fungicide difenoconazole was found to affect the development of the nervous system in zebrafish embryos, leading to inhibitory effects on heart rate and body length, increased malformation rate, and decreased locomotor activity. Difenoconazole treatment also significantly reduced dopamine and acetylcholine levels, while increasing acetylcholinesterase activity. Furthermore, the expression of genes involved in neurodevelopment was significantly altered.
Article
Biochemistry & Molecular Biology
Jong-Su Park, Palas Samanta, Sangwoo Lee, Jieon Lee, Jae-Woo Cho, Hang-Suk Chun, Seokjoo Yoon, Woo-Keun Kim
Summary: Acrylamide induces neurotoxicity and developmental toxicity in zebrafish, leading to various developmental abnormalities and impaired locomotor behavior. The zebrafish model offers a rapid and cost-efficient approach to studying acrylamide neurotoxicity.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Biochemistry & Molecular Biology
Qipeng Shi, Huaran Yang, Yangli Chen, Na Zheng, Xiaoyu Li, Xianfeng Wang, Weikai Ding, Bangjun Zhang
Summary: The pesticide trichlorfon used in aquaculture was found to cause developmental neurotoxicity in zebrafish embryos. Trichlorfon exposure led to reduced survival rate, hatching rate, heartbeat, body length, and increased malformation rate in zebrafish larvae. The neurotoxic effects were attributed to the disruption of cholinergic, dopaminergic, and serotonergic signaling, as well as the development of the central nervous system.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Toxicology
Yang Yang, Jinhe Chang, Donghui Wang, Hao Ma, Yuanbo Li, Yongquan Zheng
Summary: The study investigated the neuroendocrine disruption potential of fungicide thifluzamide on non-targeted aquatic organisms, using zebrafish embryos as a model. Results indicated that exposure to thifluzamide affected the development, behavior, and neurotransmitter levels in zebrafish embryos, suggesting developmental programming impact of this fungicide.
ARCHIVES OF TOXICOLOGY
(2021)
Article
Marine & Freshwater Biology
Dong-Dong Ma, Wen-Jun Shi, Si-Ying Li, Jin-Ge Zhang, Zhi-Jie Lu, Xiao-Bing Long, Xin Liu, Chu-Shu Huang, Guang-Guo Ying
Summary: This study found that EPH and COC had noticeable developmental neurotoxicity in early-stage zebrafish at environmentally relevant concentrations, causing effects such as irregular heart rate, cell apoptosis, abnormal behavior, and altered neurotransmitter levels.
AQUATIC TOXICOLOGY
(2023)
Article
Environmental Sciences
Taeyeon Hong, Hahyun Park, Garam An, Gwonhwa Song, Whasun Lim
Summary: This study investigated the effects of ethalfluralin on the development of zebrafish embryos. The results showed that ethalfluralin decreased the survival rate, hatching ratio, and heartbeat of zebrafish embryos. It also caused edema, apoptosis, and changes in gene expression related to apoptosis, inflammation, and angiogenesis. The study suggests that ethalfluralin can induce oxidative stress and have toxic effects on the development of zebrafish embryos.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Biochemistry & Molecular Biology
Jiaxian Liu, Yongjie Xu, Gengze Liao, Hongwei Tu, Ying Huang, Tao Peng, Xiaohui Chen, Zhibin Huang, Yiyue Zhang, Xiaojing Meng, Fei Zou
Summary: This study reveals a protective role of Ambra1 against lead-induced neural damage in developing zebrafish. Exposure to lead reduces the expression of ambra1a and ambra1b and impairs locomotor activity in zebrafish embryos. However, overexpression of ambra1a or ambra1b can reverse these effects and decrease apoptotic cell numbers in the presence of lead.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
(2022)
Article
Environmental Sciences
Ha-Na Oh, Donggon Yoo, Seungmin Park, Sangwoo Lee, Woo-Keun Kim
Summary: The study found that glutaraldehyde (GA) has potential neurotoxic effects, inhibiting neurite outgrowth and downregulating specific genes in vitro and in vivo experiments. In zebrafish embryos, GA adversely affected neural morphogenesis, leading to decreased survival and irregular hatching, among other effects.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2022)
Article
Environmental Sciences
Ha-Na Oh, Donggon Yoo, Seungmin Park, Sangwoo Lee, Woo-Keun Kim
Summary: The potential developmental neurotoxicity (DNT) of glutaraldehyde (GA) has been demonstrated in vitro and in vivo. GA inhibits neurite outgrowth and alters the expression of neurodevelopmental genes in cell models. GA also affects the early development and neural morphogenesis of zebrafish embryos, resulting in decreased survival, irregular hatching, reduced heart rate, decreased brain and spinal cord width, and decreased myelination of Schwann cells and oligodendrocytes.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2022)
Article
Engineering, Environmental
Qiyu Wang, Xueyan Gu, Yu Liu, Shuai Liu, Wuting Lu, Yongming Wu, Huiqiang Lu, Jing Huang, Wenqing Tu
Summary: This study investigated the neurotoxicity and underlying mechanisms of PFOS alternatives, F-53B and OBS, on adult zebrafish's circadian rhythms. The results showed that PFOS affected heat response rather than circadian rhythms by disrupting calcium signaling pathway transduction, while F-53B and OBS altered circadian rhythms through different mechanisms. F-53B interfered with neurotransmitter metabolism and disrupted blood-brain barrier formation, while OBS inhibited Wnt signaling transduction and induced midbrain ventriculomegaly, leading to imbalance in DA secretion and circadian rhythm changes. This study emphasizes the importance of assessing the environmental exposure risks of PFOS alternatives and understanding their multiple toxicities' mechanisms.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Environmental Sciences
Zhengkang Su, Kaiyu Guan, Yunbin Liu, Hai Zhang, Zhengwei Huang, Miaomiao Zheng, Ya Zhu, He Zhang, Weihong Song, Xi Li
Summary: The use of clinical psychoactive drugs can pose unpredictable threats to fetal development. Opicapone, a newly effective peripheral COMT inhibitor, is used for the treatment of Parkinson's disease and other dopamine-related disorders. However, the impact of opicapone on embryonic development is still unknown.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2023)
Article
Genetics & Heredity
Roman A. Li, Marja Talikka, Sylvain Gubian, Colette vom Berg, Florian Martin, Manuel C. Peitsch, Julia Hoeng, Anze Zupanic
Summary: Adverse outcomes from chemical toxicity are often caused by system-level perturbations in molecular event networks rather than individual protein dysregulation. Understanding toxicity mechanisms requires recognizing interactions of molecules, pathways, and biological processes within these networks. The developing brain, a highly complex network, presents challenges in developmental neurotoxicity, which can be addressed through the use of systems toxicology methods like computable biological networks.
FRONTIERS IN GENETICS
(2021)
Article
Marine & Freshwater Biology
Bangeppagari Manjunatha, B. Deekshitha, Eunseok Seo, Jeongju Kim, Sang Joon Lee
Summary: Research shows that exposure to PM2.5 leads to increased mortality, reduced hatching rates, lower heart rates, and various developmental abnormalities in zebrafish. It also causes damage in skin cell layers, abnormalities in neurons, heart, liver, gills, brain, and eyes, and increased organelle dissolution at cellular/subcellular levels. Further investigation is needed to understand the specific elements in diesel pollution that contribute to this toxicity.
AQUATIC TOXICOLOGY
(2021)
Article
Engineering, Environmental
Cong M. Tran, Hyojin Lee, Byoungcheun Lee, Jin-Sung Ra, Ki-Tae Kim
Summary: This study compared the developmental toxicities of six major OPEs in chorionated and dechorionated zebrafish embryos using a fixed exposure scheme. Removal of the chorion increased sensitivity to OPEs, leading to higher incidence of mortality and malformation. Behaviorally, zebrafish larvae exhibited inhibited locomotive activity by OPEs regardless of chorion presence. At the molecular level, the presence of the chorion influenced the expression of certain genes in zebrafish embryos exposed to specific OPEs.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Environmental Sciences
Eric Gyimah, Hai Xu, Xing Dong, Xuchun Qiu, Zhen Zhang, Yuanqing Bu, Osei Akoto
Summary: Exposure to low concentrations of BPA and BPS during embryonic development can have deleterious effects on the central nervous system development and induce behavioral abnormalities in zebrafish, potentially by interfering with the normal expression of development-related genes.
Review
Environmental Sciences
Attila Csaba Kondor, Anna Viktoria Vancsik, Laszlo Bauer, Lili Szabo, Zoltan Szalai, Gergely Jakab, Gabor Maasz, Marta Pedrosa, Maria Jose Sampaio, Ana Rita Lado Ribeiro
Summary: This review provides a critical overview of research on the removal efficiency of priority substances and compounds of emerging concern through bank filtration, discussing influencing factors and future challenges. The findings show that the efficiency of bank filtration is influenced by multiple factors and varies for different substances.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Xinyan Wang, Shuai Zhang, Huihui Yan, Zhao Ma, Yunshan Zhang, Haining Luo, Xueli Yang
Summary: This study investigated the association between ambient PM2.5, O3 pollution, and ovarian reserve in reproductive-aged Chinese women. The results showed that increased exposure to PM2.5 and O3 was associated with decreased AMH levels, indicating reduced ovarian reserve. Notably, the effects of O3 exposure on ovarian reserve were different from those of PM2.5 exposure.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Tingting Ma, Yanjuan Ding, Fengjiao Xu, Chen Zhang, Min Zhou, Ya Tang, Yanrong Chen, Yating Wen, Rufei Chen, Bin Tang, Shigui Wang
Summary: The dragonfly species Orthetrum albistylum can accumulate heavy metals, and its heat shock protein genes have the potential to serve as biomarkers for monitoring environmental pollutants.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Naoto Ishiwaka, Koya Hashimoto, Masayoshi K. Hiraiwa, Francisco Sanchez-Bayo, Taku Kadoya, Daisuke Hayasaka
Summary: Systemic insecticides and rising temperatures have combined effects on the abundance of Odonata nymphs in paddy fields. The standalone effect of insecticide exposure decreased the Odonata community, while nymphs decreased synergistically with temperature rise in paddy water. However, the impacts of each stressor alone varied among species.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Marco Vecchiato, Carlo Barbante, Elena Barbaro, Francois Burgay, Warren R. L. Cairns, Alice Callegaro, David Cappelletti, Federico Dallo, Marianna D'Amico, Matteo Feltracco, Jean-Charles Gallet, Andrea Gambaro, Catherine Larose, Niccolo Maffezzoli, Mauro Mazzola, Ivan Sartorato, Federico Scoto, Clara Turetta, Massimiliano Varde, Zhiyong Xie, Andrea Spolaor
Summary: The Arctic region is facing contamination from long-range pollution and local human activities. Polycyclic Aromatic Hydrocarbons (PAHs) are used as environmental indicators for emission, transport, and deposition processes. Research conducted in the Arctic surface snow in Ny-Ålesund, Svalbard from October 2018 to May 2019 shows that long-range inputs of PAHs mainly occur in winter, while the most abundant analyte retene exhibits opposite seasonal trends.
ENVIRONMENTAL POLLUTION
(2024)
Review
Environmental Sciences
Maoshui Zhuo, Zhijie Chen, Xiaoqing Liu, Wei Wei, Yansong Shen, Bing-Jie Ni
Summary: This paper discusses the application of three catalytic processes (photocatalysis, electrocatalysis, and biocatalysis) in the management of microplastic pollution, and introduces the efficiency and catalytic mechanisms of different catalysts. It also proposes the development prospects for sustainable management of microplastic pollution.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Shiyu Chen, Zhenzhen Shi, Qiang Zhang
Summary: In this study, a human physiologically based pharmacokinetic (PBPK) model of diethyl phthalate (DEP) was developed to assess its toxicity. The model considers the distribution and metabolism of DEP and its active metabolite monoethyl phthalate (MEP) in different tissue compartments. Sensitivity analysis and Bayesian Markov chain Monte Carlo (MCMC) simulations were performed to evaluate the uncertainty and variability of the model parameters. The results suggest that dermal absorption is an important route of exposure to DEP in the environment.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Bangguo Wang, Lijing Wang, Wenxi Cen, Tao Lyu, Peter Jarvis, Yang Zhang, Yuanxun Zhang, Yinghui Han, Lei Wang, Gang Pan, Kaili Zhang, Wei Fan
Summary: This study investigates the feasibility and mechanisms of a chemical-free nanobubble-based AOP for treating organic micropollutants in water. The results show that the oxygen nanobubble AOP has a significantly higher removal efficiency compared to air and nitrogen nanobubbles. The treatment performance is not affected by pH and the presence of ions. Higher initial concentrations of the micropollutant lead to slower treatment processes, but similar removal performance is achieved in the end. The presence of organic matter reduces the removal rate of the micropollutant. The results have practical feasibility for water and wastewater treatment.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Yingmei Huang, Jicai Yi, Yao Huang, Songxiong Zhong, Bin Zhao, Jing Zhou, Yuxuan Wang, Yiwen Zhu, Yanhong Du, Fangbai Li
Summary: This study investigates the impact of biochar on methylmercury (MeHg) accumulation in rice. The results show that biochar reduces MeHg levels in paddy soils by decreasing bioavailable Hg and microbial Hg methylation. Additionally, biochar decreases the uptake and translocation of MeHg in rice plants, resulting in a reduction of MeHg accumulation in rice grains.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Nengde Zeng, Fei Huang, Jiani Du, Chenghao Huang, Qian Yang, Xinhua Zhan, Baoshan Xing
Summary: This study investigates the protein targets and protein-ligand interactions related to PAH contamination in crop xylem sap using computational tools. The results show that phenanthrene has a more pronounced effect on the xylem sap proteins of maize and wheat, with maize DEPs associated with lipid biosynthesis and wheat DEPs exhibiting an increase in ABC transporters. This study provides insights into the regulation and movement of PAHs within plant xylem.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Xinwei Chen, Hao Ma, Run Wang, Man Wang, Binbin Zhu, Yanqing Cong, Xiayue Zhu, Guoqin Wang, Yi Zhang
Summary: Co3O4/TiO2-NRs electrodes with excellent photoresponse were prepared via plasma-assisted modification of Co3O4 on TiO2. The combination of Co3O4 and TiO2 improved the light utilization efficiency and showed potential for degradation of pollutants.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Wenjing Ji, Liying Song, Jing Wang, Hongqing Song
Summary: This study conducted a life-cycle assessment to examine the correlation between natural gas consumption and carbon emissions in different end uses in China. The results showed that both natural gas consumption and life-cycle carbon emissions have been increasing since 2017. Significant variations in NG life-cycle carbon emissions were found across different provinces and sectors, highlighting the need for targeted efforts to reduce carbon emissions.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Youyi Chen, Boxuan Zhang, Pojun Zhang, Guogui Shi, Hao Liang, Wu Cai, Jingyu Gao, Sumin Zhuang, Kaiyin Luo, Jiaqi Zhu, Chaoxiang Chen, Kunyu Ma, Jinrong Chen, Chun Hu, Xueci Xing
Summary: The synergistic effects of trace sulfadiazine and cast-iron corrosion scales on the formation of disinfection by-products in drinking water distribution systems were investigated. The presence of magnetite resulted in increased concentrations of DBPs due to the higher microbial activity and enhanced microbial extracellular electron transport pathway. The study highlights the importance of considering trace antibiotics pollution and corrosion scales in water sources for DBP control.
ENVIRONMENTAL POLLUTION
(2024)
Review
Environmental Sciences
Bishwa Raj Pokharel, Vijay Sheri, Manoj Kumar, Zhiyong Zhang, Baohong Zhang
Summary: This review summarizes the interactions, uptake, and transport of aluminum nanoparticles (Al-NPs) in plants, highlighting their negative effects on plant growth and development, as well as their potential to alter plant defense systems and gene expression.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Yonglu Wang, Fengsong Zhang, Xiaoyong Liao, Xiao Yang, Guixiang Zhang, Liyun Zhang, Chaojun Wei, Pengge Shi, Jiongxin Wen, Xiaorong Ju, Can Xu, Yang Liu, Ying Lan
Summary: This study aims to explore the effects of thiencarbazone-methyl center dot isoxaflutole on soil microflora and the potential mitigation mechanisms to bacterial communities. It was found that increasing the application of thiencarbazone-methyl center dot isoxaflutole resulted in increased stress on soil bacterial community structure and diversity. Increasing soil pH was recognized as a key factor in improving the diversity and structure of soil microflora. Supplemental use of nitrapyrin or modified attapulgite can increase soil pH and improve bacterial diversity.
ENVIRONMENTAL POLLUTION
(2024)