Assessment of a panel of cellular biomarkers and the kinetics of their induction in comparing genotoxic modes of action in HepG2 cells
出版年份 2018 全文链接
标题
Assessment of a panel of cellular biomarkers and the kinetics of their induction in comparing genotoxic modes of action in HepG2 cells
作者
关键词
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出版物
ENVIRONMENTAL AND MOLECULAR MUTAGENESIS
Volume -, Issue -, Pages -
出版商
Wiley
发表日期
2018-04-18
DOI
10.1002/em.22197
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Interlaboratory evaluation of a multiplexed high information content in vitro genotoxicity assay
- (2017) Steven M. Bryce et al. ENVIRONMENTAL AND MOLECULAR MUTAGENESIS
- ATM, ATR, and DNA-PK: The Trinity at the Heart of the DNA Damage Response
- (2017) Andrew N. Blackford et al. MOLECULAR CELL
- Ubiquitin-like modifications in the DNA damage response
- (2017) Zhifeng Wang et al. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- Genotoxic mode of action predictions from a multiplexed flow cytometric assay and a machine learning approach
- (2016) Steven M. Bryce et al. ENVIRONMENTAL AND MOLECULAR MUTAGENESIS
- Complementarity of phosphorylated histones H2AX and H3 quantification in different cell lines for genotoxicity screening
- (2015) Laure Khoury et al. ARCHIVES OF TOXICOLOGY
- An Integrated Approach for Analysis of the DNA Damage Response in Mammalian Cells
- (2015) Jun-Hyuk Choi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Regulation of deoxynucleotide metabolism in cancer: novel mechanisms and therapeutic implications
- (2015) Rebecca Kohnken et al. Molecular Cancer
- Dynamic alteration in H3 serine 10 phosphorylation is G1-phase specific during ionization radiation induced DNA damage response in human cells
- (2015) Ajit K. Sharma et al. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- Interpreting in vitro micronucleus positive results: Simple biomarker matrix discriminates clastogens, aneugens, and misleading positive agents
- (2014) Steven M. Bryce et al. ENVIRONMENTAL AND MOLECULAR MUTAGENESIS
- DNA breaks and chromosomal aberrations arise when replication meets base excision repair
- (2014) Michael Ensminger et al. JOURNAL OF CELL BIOLOGY
- Development of pharmacodynamic biomarkers for ATR inhibitors
- (2014) Tao Chen et al. Molecular Oncology
- The DNA Damage Response Induced by Infection with Human Cytomegalovirus and Other Viruses
- (2014) Xiaofei E et al. Viruses-Basel
- Validation of high-throughput genotoxicity assay screening using γH2AX in-cell western assay on HepG2 cells
- (2013) Laure Khoury et al. ENVIRONMENTAL AND MOLECULAR MUTAGENESIS
- The ATM protein kinase: regulating the cellular response to genotoxic stress and more
- (2013) Yosef Shiloh et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- A Mode-of-Action Approach for the Identification of Genotoxic Carcinogens
- (2013) Lya G. Hernández et al. PLoS One
- DNA damage-induced cell death: From specific DNA lesions to the DNA damage response and apoptosis
- (2012) Wynand P. Roos et al. CANCER LETTERS
- Genotoxicity of pesticide mixtures present in the diet of the French population
- (2012) Vanessa Graillot et al. ENVIRONMENTAL AND MOLECULAR MUTAGENESIS
- Performance of in vitro γH2AX assay in HepG2 cells to predict in vivo genotoxicity
- (2012) Maria Tsamou et al. MUTAGENESIS
- Evidence of the in vitro genotoxicity of methyl-pyrazole pesticides in human cells
- (2012) Vanessa Graillot et al. MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
- DNA breaks and chromosome pulverization from errors in mitosis
- (2012) Karen Crasta et al. NATURE
- Eukaryotic DNA damage checkpoint activation in response to double-strand breaks
- (2011) Karen Finn et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- The DNA Damage Response Induces IFN
- (2011) Sabrina Brzostek-Racine et al. JOURNAL OF IMMUNOLOGY
- Prolonged mitotic arrest triggers partial activation of apoptosis, resulting in DNA damage and p53 induction
- (2011) James D. Orth et al. MOLECULAR BIOLOGY OF THE CELL
- Development and validation of a high-content screening in vitro micronucleus assay in CHO-k1 and HepG2 cells
- (2011) Walter M.A. Westerink et al. MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
- The MRE11 complex: starting from the ends
- (2011) Travis H. Stracker et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Chromosome Segregation Errors as a Cause of DNA Damage and Structural Chromosome Aberrations
- (2011) A. Janssen et al. SCIENCE
- DNA Adducts of Decarbamoyl Mitomycin C Efficiently Kill Cells without Wild-Type p53 Resulting from Proteasome-Mediated Degradation of Checkpoint Protein 1
- (2010) Ernest K. Boamah et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Homologous recombination protects mammalian cells from replication-associated DNA double-strand breaks arising in response to methyl methanesulfonate
- (2010) Teodora Nikolova et al. DNA REPAIR
- Similarities and Differences in the Expression of Drug-Metabolizing Enzymes between Human Hepatic Cell Lines and Primary Human Hepatocytes
- (2010) L. Guo et al. DRUG METABOLISM AND DISPOSITION
- Role of oxidatively induced DNA lesions in human pathogenesis
- (2010) Olga A. Sedelnikova et al. MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH
- Pathways of mammalian replication fork restart
- (2010) Eva Petermann et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Use of the γH2AX assay for assessing the genotoxicity of polycyclic aromatic hydrocarbons in human cell lines
- (2010) M. Audebert et al. TOXICOLOGY LETTERS
- Activation of P53 in HepG2 cells as surrogate to detect mutagens and promutagens in vitro
- (2010) Kathleen Boehme et al. TOXICOLOGY LETTERS
- The development of RAD51C, Cystatin A, p53 and Nrf2 luciferase-reporter assays in metabolically competent HepG2 cells for the assessment of mechanism-based genotoxicity and of oxidative stress in the early research phase of drug development
- (2009) Walter M.A. Westerink et al. MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
- The DNA-damage response in human biology and disease
- (2009) Stephen P. Jackson et al. NATURE
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