Article
Biochemistry & Molecular Biology
Maria Jalbrzikowski, Amy Lin, Ariana Vajdi, Vardui Grigoryan, Leila Kushan, Christopher R. K. Ching, Charles Schleifer, Rebecca A. Hayes, Stephanie A. Chu, Catherine A. Sugar, Jennifer K. Forsyth, Carrie E. Bearden
Summary: By probing naturally-occurring reciprocal genomic copy number variations (CNVs), this study sheds light on altered neurodevelopment in 22q11.2 CNV carriers. The research reveals distinct longitudinal trajectories of cortical thickness (CT) and cortical surface area (SA) in different CNV carriers, as well as their associations with clinical outcomes. The findings offer new insights into the neural mechanisms underlying deviations from typical brain development.
MOLECULAR PSYCHIATRY
(2022)
Article
Neurosciences
Nandita Vijayakumar, George J. Youssef, Nicholas B. Allen, Vicki Anderson, Daryl Efron, Philip Hazell, Lisa Mundy, Jan M. Nicholson, George Patton, Marc L. Seal, Julian G. Simmons, Sarah Whittle, Tim Silk
Summary: Adolescence is a period where the brain undergoes extensive changes, particularly related to puberty, which can impact cortical thickness and trajectories. The study found that males with faster pubertal tempo showed greater thinning in certain cortical areas, indicating the unique influence of puberty on cortical development and the importance of individual differences in this process.
Article
Neurosciences
Travis White-Schwoch, Jennifer Krizman, Trent Nicol, Nina Kraus
Summary: A person with auditory neuropathy did not show frequency-following responses to musical notes within 65-130 Hz octaves, while a control subject did exhibit synchronized responses. This study suggests that subcortical neural synchrony is crucial for generating frequency-following responses, even when cortical onset responses are present.
JOURNAL OF NEUROPHYSIOLOGY
(2021)
Article
Psychology, Clinical
Divyangana Rakesh, Reham Elzeiny, Nandita Vijayakumar, Sarah Whittle
Summary: This study investigated the associations between childhood maltreatment, adolescent brain development and mental health trajectories. The findings showed significant differences in the associations between childhood maltreatment and the volume development of amygdala and hippocampus, as well as the coupling between subcortical regions and prefrontal cortex. Additionally, the study found that brain development played a mediating role in the association between maltreatment and depressive and anxiety symptom trajectories.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Multidisciplinary Sciences
Melanie J. Grubisha, Tao Sun, Leanna Eisenman, Susan L. Erickson, Shinnyi Chou, Cassandra D. Helmer, Melody T. Trudgen, Ying Ding, Gregg E. Homanics, Peter Penzes, Zachary P. Wills, Robert A. Sweet
Summary: The study demonstrates that the development of neuronal dendrites is regulated by the Nogo receptor 1 pathway, which is stimulated by OMGp and requires the Rho guanine nucleotide exchange factor Kalirin-9. The research also shows that a missense mutation in the Kalrn gene identified in a schizophrenia cohort may lead to abnormal neuronal dendritic function, affecting the perception of gap durations in sound.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Virology
Lais Cristine Delgado da Hora, Lilian Ferreira Muniz, Leonardo Gleygson Angelo Venancio, Karina Paes Advincula, Jessica Dayane da Silva, Diana Babini Lapa de Albuquerque Britto, Democrito de Barros Miranda Filho, Elizabeth B. Brickley, Ricardo Arraes de Alencar Ximenes, Silvio da Silva Caldas Neto, Mariana de Carvalho Leal
Summary: Prenatal exposure to ZIKV can have negative effects on auditory pathways, but CAEP testing can reveal preserved neural function. MRI results show structural changes in the brains of microcephalic children, but CAEP results indicate that these children still have some ability to process sound stimuli.
Article
Medicine, General & Internal
Dayane Domeneghini Didone, Lilian Sanches Oliveira, Alessandra Spada Durante, Katia de Almeida, Michele Vargas Garcia, Rudimar dos Santos Riesgo, Pricila Sleifer
Summary: The study found that the latency values of cortical auditory-evoked potentials at birth were significantly higher than those at three months, and the latency values of the preterm group were also higher than those of the term group, regardless of frequency and time of evaluation. In general, the latency of cortical auditory-evoked potentials was higher at high frequencies. Amplitude values in the third month of life were significantly higher than those in the first month for both term and preterm infants.
Review
Neurosciences
Paul G. Anastasiades, Luisa De Vivo, Michele Bellesi, Matt W. Jones
Summary: Modern life poses threats to sleep, especially during adolescence where sleep disruption may have a lasting impact on the development of the prefrontal cortex. Acknowledging the contribution of adolescent sleep to brain development and mental health is important.
PROGRESS IN NEUROBIOLOGY
(2022)
Article
Neurosciences
Erol J. Ozmeral, David A. Eddins, Ann Clock Eddins
Summary: The study investigated the modulatory effects of attention on cortical encoding of spatial change in younger and older listeners with normal hearing thresholds. Results suggested that both age groups showed modulatory effects of attention on spatial-change tuning, indicating that selective attention enhances electrical responses to spatial changes in both young and older listeners.
JOURNAL OF NEUROPHYSIOLOGY
(2021)
Article
Neurosciences
Suranjana Pal, Deepanjali Dwivedi, Tuli Pramanik, Geeta Godbole, Takuji Iwasato, Denis Jabaudon, Upinder S. Bhalla, Shubha Tole
Summary: Loss of the LHX2 gene in cortical progenitors results in premature ingrowth of thalamocortical afferents into the cortex, leading to atrophy of the sensory thalamus and nearly eliminating sensory innervation to the cortex. This indicates a profound mechanism operating in subplate progenitors affecting the growth of thalamocortical axons into the cortex.
JOURNAL OF NEUROSCIENCE
(2021)
Article
Neurosciences
Renske van der Cruijsen, Neeltje E. Blankenstein, Jochem P. Spaans, Sabine Peters, Eveline A. Crone
Summary: This longitudinal behavioral neuroimaging study aimed to investigate self-concept development in adolescence, specifically in terms of domain-specific self-concept and similarity between own and perceived peers' opinions. The results showed a decline in self-concept positivity during mid-adolescence, particularly in the academic domain, indicating domain differentiation. Brain activation related to self-evaluations was observed in the medial prefrontal cortex and temporal-parietal junction, with adolescence-associated peak activation in the medial prefrontal cortex for direct self-evaluations. The activation in the temporal-parietal junction was generally stronger for reflected self-evaluations and increased linearly with age for both types of self-evaluations. Longitudinal prediction analyses revealed the positive self-evaluations predicted increased self-concept clarity and reduced fear of negative evaluation in the future. Overall, this study highlights the importance of developing a coherent and positive self-concept during adolescence.
SOCIAL COGNITIVE AND AFFECTIVE NEUROSCIENCE
(2023)
Article
Neurosciences
Na Chen, Chenxi Zhao, Meng Wang, Jeffery A. Jones, Peng Liu, Xi Chen, Gaolong Gong, Hanjun Liu
Summary: The study found that greater gray-matter volume in the left inferior parietal lobule and greater cortical thickness and surface area in various temporal and parietal regions were associated with larger vocal responses to feedback errors. On the other hand, greater cortical thickness in the right inferior frontal gyrus and superior parietal lobule, as well as surface area in the left precuneus and cuneus, were correlated with smaller magnitudes of vocal responses.
Article
Neurosciences
Graham L. Baum, John C. Flournoy, Matthew F. Glasser, Michael P. Harms, Patrick Mair, Ashley F. P. Sanders, Deanna M. Barch, Randy L. Buckner, Susan Bookheimer, Mirella Dapretto, Stephen Smith, Kathleen M. Thomas, Essa Yacoub, David C. Van Essen, Leah H. Somerville
Summary: This study used high-resolution brain imaging techniques to reveal the timing of cortical myelination during human adolescence and its importance in cognitive and behavioral development.
JOURNAL OF NEUROSCIENCE
(2022)
Article
Biology
Ryszard Auksztulewicz, Vani Gurusamy Rajendran, Fei Peng, Jan Wilbert Hendrik Schnupp, Nicol Spencer Harper
Summary: This study used invasive recordings to investigate omission responses in the auditory cortex of anesthetized rats. The results showed that omission responses were observed in LFP and AMUA signals, but not in spiking activity. The amplitude of omission response was lower and latency was longer compared to burst-evoked sensory responses, and it increased as the number of preceding bursts increased.
Article
Neurosciences
Ethan M. McCormick, Sabine Peters, Eveline A. Crone, Eva H. Telzer
Summary: The study utilized a novel longitudinal modeling approach to uncover nonlinear patterns of development in both behavior and brain. Greater experience was found to support increased learning and network modularity, with heightened network modularity predicting improved learning following the transition from adolescence to young adulthood.
Article
Audiology & Speech-Language Pathology
Jessica Slater, Nina Kraus, Kali Woodruff Carr, Adam Tierney, Andrea Azem, Richard Ashley
LANGUAGE COGNITION AND NEUROSCIENCE
(2018)
Article
Audiology & Speech-Language Pathology
Lori L. Holt, Adam T. Tierney, Giada Guerra, Aeron Laffere, Frederic Dick
Article
Neurosciences
Jessica Slater, Richard Ashley, Adam Tierney, Nina Kraus
JOURNAL OF COGNITIVE NEUROSCIENCE
(2018)
Meeting Abstract
Clinical Neurology
A. B. Fitzroy, A. Cremone, R. M. Spencer
Meeting Abstract
Clinical Neurology
K. Kainec, A. B. Fitzroy, R. M. Spencer
Article
Audiology & Speech-Language Pathology
Ahren B. Fitzroy, Mara Breen
LANGUAGE AND SPEECH
(2020)
Article
Neurosciences
Mara Breen, Ahren B. Fitzroy, Michelle Oraa Ali
Article
Neurosciences
Ahren B. Fitzroy, Kyle A. Kainec, Rebecca M. C. Spencer
Summary: Age-related changes in grey matter volume mediate and moderate differences in neuroscillatory activity during a midday nap, with older adults showing reduced delta, theta, and sigma amplitude compared to young adults. Grey matter loss in specific brain regions mediates these frequency-specific changes, while putamen and pallidum grey matter volume moderates the effects. Older adults with more grey matter show either unchanged or decreased neural activity, contrasting with young adults who show increased activity with more grey matter.
EUROPEAN JOURNAL OF NEUROSCIENCE
(2021)
Article
Behavioral Sciences
Ahren B. Fitzroy, Kyle A. Kainec, Jeehye Seo, Rebecca M. C. Spencer
Summary: The study found that older adults demonstrate sleep-dependent consolidation of motor sequence learning after a daytime nap, while young adults showed high SRTT performance prior to the sleep interval and did not show further sleep-dependent performance improvements. The results suggest that aging-related deficiencies in fast learning processes may contribute to the observed sleep-dependent consolidation deficits in older adults.
NEUROBIOLOGY OF LEARNING AND MEMORY
(2021)
Article
Geriatrics & Gerontology
Ahren B. Fitzroy, Bethany J. Jones, Kyle A. Kainec, Jeehye Seo, Rebecca M. C. Spencer
Summary: This study found that oscillatory neural activity during sleep, which is important for motor learning consolidation, decreases with typical aging. Brain regions involved in motor learning contribute to oscillatory neural activity during subsequent sleep more in younger adults compared to older adults.
FRONTIERS IN AGING NEUROSCIENCE
(2022)
Article
Psychology, Experimental
Adrian Rivera-Rodriguez, Maxwell Sherwood, Ahren B. Fitzroy, Lisa D. Sanders, Nilanjana Dasgupta
Summary: This study found that anger can lead to increased attention to faces, decreased attention to race, but had no impact on error recognition. Additionally, anger slowed overall task performance, especially the correct identification of harmless objects.
COGNITIVE RESEARCH-PRINCIPLES AND IMPLICATIONS
(2021)
Meeting Abstract
Clinical Neurology
Katrina Rodheim, Ahren Fitzroy, Bethany Jones, Jen Holmes, Sanna Lokhandwala, Rebecca Spencer
Article
Psychology, Multidisciplinary
Bethany J. Jones, Ahren B. Fitzroy, Rebecca M. C. Spencer
FRONTIERS IN PSYCHOLOGY
(2019)
Article
Music
Adam Tierney, Aniruddh D. Patel, Mara Breen
Article
Psychology, Experimental
Adam Tierney, Aniruddh D. Patel, Mara Breen
JOURNAL OF EXPERIMENTAL PSYCHOLOGY-GENERAL
(2018)