Epigenetic regulators Rbbp4 and Hdac1 are overexpressed in a zebrafish model of RB1 embryonal brain tumor, and are required for neural progenitor survival and proliferation

Disease Association and Druggability of WD40 Repeat Proteins

(2017) Richard Song et al.   JOURNAL OF PROTEOME RESEARCH

CBTRUS Statistical Report: Primary brain and other central nervous system tumors diagnosed in the United States in 2010–2014

(2017) Quinn T Ostrom et al.   NEURO-ONCOLOGY

The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis

(2017) Issam Aldiri et al.   NEURON

Development of zebrafish medulloblastoma-like PNET model by TALEN-mediated somatic gene inactivation

(2017) Jaegal Shim et al.   Oncotarget

The DREAM complex through its subunit Lin37 cooperates with Rb to initiate quiescence

(2017) Christina FS Mages et al.   eLife

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs

(2016) Dominik Sturm et al.   CELL

A common strategy for initiating the transition from proliferation to quiescence

(2016) Shawna Miles et al.   CURRENT GENETICS

RB1: a prototype tumor suppressor and an enigma

(2016) Nicholas J. Dyson   GENES & DEVELOPMENT

RB regulates the production and the survival of newborn neurons in the embryonic and adult dentate gyrus

(2016) Renaud Vandenbosch et al.   HIPPOCAMPUS

COSMIC: somatic cancer genetics at high-resolution

(2016) Simon A. Forbes et al.   NUCLEIC ACIDS RESEARCH

Retinoblastoma Binding Protein 4 Modulates Temozolomide Sensitivity in Glioblastoma by Regulating DNA Repair Proteins

(2016) Gaspar J. Kitange et al.   Cell Reports

MEK Inhibitors Reverse Growth of Embryonal Brain Tumors Derived from Oligoneural Precursor Cells

(2016) Katarzyna Modzelewska et al.   Cell Reports

Reconstruction of gene regulatory networks reveals chromatin remodelers and key transcription factors in tumorigenesis

(2016) Valeriya Malysheva et al.   Genome Medicine

Role of the Retinoblastoma protein, Rb, during adult neurogenesis in the olfactory bulb

(2016) Rayan Naser et al.   Scientific Reports

The Incidence of Trilateral Retinoblastoma: A Systematic Review and Meta-Analysis

(2015) Marcus C. de Jong et al.   AMERICAN JOURNAL OF OPHTHALMOLOGY

Inhibition of Pluripotency Networks by the Rb Tumor Suppressor Restricts Reprogramming and Tumorigenesis

(2015) Michael S. Kareta et al.   Cell Stem Cell

PRC2 mediated H3K27 methylations in cellular identity and cancer

(2015) Eric Conway et al.   CURRENT OPINION IN CELL BIOLOGY

High-throughput gene targeting and phenotyping in zebrafish using CRISPR/Cas9

(2015) Gaurav K. Varshney et al.   GENOME RESEARCH

Histone deacetylases 1 and 2 are required for brain development

(2015) Joanna Jaworska et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Rapid tumor induction in zebrafish by TALEN-mediated somatic inactivation of the retinoblastoma1 tumor suppressor rb1

(2015) Staci L. Solin et al.   Scientific Reports

Transcriptional control of stem cell fate by E2Fs and pocket proteins

(2015) Lisa M. Julian et al.   Frontiers in Genetics

Cross-species genomic and epigenomic landscape of retinoblastoma

(2015) Claudia A. Benavente et al.   Oncotarget

Making designer mutants in model organisms

(2014) Y. Peng et al.   DEVELOPMENT

Insight into the Architecture of the NuRD Complex

(2014) Saad S. M. Alqarni et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genome-wide, whole mount in situ analysis of transcriptional regulators in zebrafish embryos

(2013) Olivier Armant et al.   DEVELOPMENTAL BIOLOGY

Distinct Functional and Temporal Requirements for Zebrafish Hdac1 during Neural Crest-Derived Craniofacial and Peripheral Neuron Development

(2013) Myron S. Ignatius et al.   PLoS One

Epigenetic Reprogramming in Cancer

(2013) M. L. Suva et al.   SCIENCE

Cancer Genome Landscapes

(2013) B. Vogelstein et al.   SCIENCE

The retinoblastoma tumor suppressor and stem cell biology

(2012) J. Sage   GENES & DEVELOPMENT

Markers of survival and metastatic potential in childhood CNS primitive neuro-ectodermal brain tumours: an integrative genomic analysis

(2012) Daniel Picard et al.   LANCET ONCOLOGY

A novel retinoblastoma therapy from genomic and epigenetic analyses

(2012) Jinghui Zhang et al.   NATURE

In vivo genome editing using a high-efficiency TALEN system

(2012) Victoria M. Bedell et al.   NATURE

Coordinated repression of cell cycle genes by KDM5A and E2F4 during differentiation

(2012) M. L. Beshiri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Tumor Suppressor Gene Retinoblastoma-1 Is Required for Retinotectal Development and Visual Function in Zebrafish

(2012) Michael Gyda et al.   PLoS Genetics

Cooperativity within and among Pten, p53, and Rb Pathways Induces High-Grade Astrocytoma in Adult Brain

(2011) Lionel M.L. Chow et al.   CANCER CELL

Chromatin-modifying Complex Component Nurf55/p55 Associates with Histones H3 and H4 and Polycomb Repressive Complex 2 Subunit Su(z)12 through Partially Overlapping Binding Sites

(2011) Agnieszka J. Nowak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Somatic Mutagenesis with a Sleeping Beauty Transposon System Leads to Solid Tumor Formation in Zebrafish

(2011) Maura McGrail et al.   PLoS One

Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1

(2011) W. Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ubiquitous transgene expression and Cre-based recombination driven by the ubiquitin promoter in zebrafish

(2010) C. Mosimann et al.   DEVELOPMENT

Moesin1 and Ve-cadherin are required in endothelial cells during in vivo tubulogenesis

(2010) Y. Wang et al.   DEVELOPMENT

The histone demethylase UTX enables RB-dependent cell fate control

(2010) J. K. Wang et al.   GENES & DEVELOPMENT

Physiological Roles of Class I HDAC Complex and Histone Demethylase

(2010) Tomohiro Hayakawa et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Rb regulates fate choice and lineage commitment in vivo

(2010) Eliezer Calo et al.   NATURE

Combinations of genetic mutations in the adult neural stem cell compartment determine brain tumour phenotypes

(2009) Thomas S Jacques et al.   EMBO JOURNAL

Transparent Adult Zebrafish as a Tool for In Vivo Transplantation Analysis

(2008) Richard Mark White et al.   Cell Stem Cell

Structural basis of histone H4 recognition by p55

(2008) J.-J. Song et al.   GENES & DEVELOPMENT

Structural Basis for the Recognition of Histone H4 by the Histone-Chaperone RbAp46

(2008) Natalia V. Murzina et al.   STRUCTURE

colgate/hdac1 repression of foxd3 expression is required to permit mitfa-dependent melanogenesis

(2007) Myron S. Ignatius et al.   DEVELOPMENTAL BIOLOGY