Article
Endocrinology & Metabolism
Shuping Yang, Xiangxiang Shi, Wanlu Liu, Zhaokai Wang, Ruoshui Li, Xianzhi Xu, Chaofan Wang, Lei Li, Ruili Wang, Tongda Xu
Summary: This study found a significant association between high TyG-BMI and the risk of heart failure in individuals with diabetes mellitus or prediabetes mellitus.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Rongsheng Wang, Longlong Dai, Yanjia Zhong, Guobo Xie
Summary: The study found a stable positive correlation between TyG-BMI and NAFLD, with a non-linear relationship, threshold effects, and saturation effects. TyG-BMI was shown to better predict the risk of NAFLD compared to traditional indicators, especially in young, middle-aged, and non-obese individuals.
LIPIDS IN HEALTH AND DISEASE
(2021)
Article
Public, Environmental & Occupational Health
Xiaomin Fu, Hongzhou Liu, Jing Liu, Nan Li, Lele Li, Dianshan Ke, Minyan Liu, Yanhui Lu, Lihua Duan, Linlin Ma, Yanfei Huo, Qinghua Lei, Shuangtong Yan
Summary: This study found that the triglyceride-glucose index is independently associated with the risk of incident type 2 diabetes mellitus (T2DM) in Chinese adults aged over 75 years. The index may be useful in monitoring T2DM in older populations.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Endocrinology & Metabolism
Xianxuan Wang, Yanjuan Chen, Zegui Huang, Zefeng Cai, Xinran Yu, Zekai Chen, Linyao Li, Guanzhi Chen, Kuangyi Wu, Huancong Zheng, Shouling Wu, Youren Chen
Summary: This study found that variability in the triglyceride-glucose index is associated with a higher risk of diabetes in the Chinese population.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Endocrinology & Metabolism
Jung A. Kim, Jinsil Kim, Eun Roh, So-hyeon Hong, You-Bin Lee, Sei Hyun Baik, Kyung Mook Choi, Eunjin Noh, Soon Young Hwang, Geum Joon Cho, Hye Jin Yoo
Summary: This study evaluated the association between pre-pregnancy TyG index and GDM in primipara women, finding that an increased TyG index was linked to a higher risk of GDM. The results suggest that elevation of the TyG index may serve as an early marker for GDM, with a more profound impact in individuals aged 35 years and older, with obesity, impaired fasting glucose, who are current smokers, or have a family history of diabetes mellitus.
DIABETES RESEARCH AND CLINICAL PRACTICE
(2021)
Article
Endocrinology & Metabolism
Shenghao Wu, Yanhong Wu, Lizi Fang, Junzhao Zhao, Yaoyao Cai, Weiting Xia
Summary: This analysis revealed a negative association between the TyG-BMI index and testosterone levels in adult males, using data from the National Health and Nutrition Examination Survey (NHANES). The study also found that the predictive ability of the TyG-BMI index for testosterone deficiency was superior to that of HOMA-IR and TyG indices.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Nutrition & Dietetics
Feifei Wang, Ting He, Guoliang Wang, Tuo Han, Zhongqiang Yao
Summary: This study suggests that TyG-BMI is a useful tool for assessing the risk of NSCLC. Individuals with high TyG-BMI should be monitored and lifestyle modifications are needed to prevent the occurrence of NSCLC.
FRONTIERS IN NUTRITION
(2022)
Article
Nutrition & Dietetics
Qunyan Xiang, Hui Xu, Junkun Zhan, Shuzhen Lu, Shuang Li, Yanjiao Wang, Yi Wang, Jieyu He, Yuqing Ni, Linsen Li, Yiyang Liu, Youshuo Liu
Summary: This study aimed to explore the association between insulin resistance (IR) and vitamin D deficiency (VDD). A negative correlation between the triglyceride-glucose (TyG) index and vitamin D level was found in patients with type 2 diabetes mellitus (T2DM). After adjusting for clinical and laboratory parameters, it was revealed that patients with higher TyG index had an increased risk of VDD in the T2DM population.
Article
Clinical Neurology
Zongyi Hou, Yuesong Pan, Yindong Yang, Xiaofan Yang, Xianglong Xiang, Yilong Wang, Zixiao Li, Xingquan Zhao, Hao Li, Xia Meng, Yongjun Wang
Summary: The study found that overweight/obese patients with ischemic stroke have significantly lower all-cause mortality than low/normal weight patients, and this difference is not associated with the TYG index. Additionally, no association between BMI and TYG index was found.
FRONTIERS IN NEUROLOGY
(2021)
Article
Endocrinology & Metabolism
Yan Zeng, Li Yin, Xiaoping Yin, Danqing Zhao
Summary: The TyG index is positively correlated with GDM, even after adjusting for confounding variables. Subgroup analysis showed consistent correlations and no difference in the TyG index among the first trimester subgroup. However, the TyG index has limited diagnostic efficacy for GDM.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Geriatrics & Gerontology
Rui Song, Xuejiao Chen, Kun He, Xueqi Hu, Kaizhi Bai, Wenlong Shi, Songhe Shi
Summary: This study aimed to explore the association between body mass index (BMI) and mortality in elderly Chinese individuals with different glycemic statuses. The results showed that higher BMI was associated with reduced mortality in individuals with normal fasting glucose (NFG) and type 2 diabetes mellitus (T2DM), but not in individuals with impaired fasting glucose (IFG).
Article
Endocrinology & Metabolism
Bei Song, Xiaofang Zhao, Tianci Yao, Weilin Lu, Hao Zhang, Ting Liu, Chengyun Liu, Kun Wang
Summary: This longitudinal cohort study demonstrated a positive correlation between baseline TyG-BMI and the risk of incident T2DM in Japanese individuals with normal glycemic levels. The risk was significantly higher in young people, women, the non-hypertensive population, and non-drinkers.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Endocrinology & Metabolism
Chen Wang, Yumei Wei, Yide Yang, Rina Su, Geng Song, Lingying Kong, Huixia Yang
Summary: The study found that first-trimester fasting plasma glucose levels are positively correlated with the incidence of adverse pregnancy outcomes, with FPG levels being able to predict abnormal outcomes even when the oral glucose tolerance test results are normal. Greater attention and management should be given to women in early pregnancy with FPG levels above 5.10 mmol/L, especially those with a BMI of 24 kg/m² or higher.
DIABETES RESEARCH AND CLINICAL PRACTICE
(2021)
Article
Endocrinology & Metabolism
Fei Guo, Yindi Liu, Zheng Ding, Yong Zhang, Chen Zhang, Jianxia Fan
Summary: The study found that increased maternal fasting plasma glucose levels in early pregnancy are closely related to fetal growth, and maternal characteristics may modify the relationship between glucose levels and fetal adiposity in late pregnancy.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Joo Hyung Lee, Seok-Jae Heo, Yu-Jin Kwon
Summary: This study aimed to examine the association between the TyG index and modified TyG indices with new-onset hypertension and their predictive ability, stratified by sex. The results showed that TyG and TyG-body mass index were significantly associated with new-onset hypertension only in women, while TyG-waist circumference and TyG-waist-to-height ratio were significantly associated with new-onset hypertension in both men and women. Therefore, a sex-specific approach is required when using TyG and modified TyG indices to identify individuals at risk of incident hypertension.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
