期刊
ACS APPLIED MATERIALS & INTERFACES
卷 7, 期 32, 页码 17552-17557出版社
AMER CHEMICAL SOC
DOI: 10.1021/ACSAMI.5B04022
关键词
magnetic nanoparticle; quantum dots; photoluminescence; complexation reaction; targeted cellular imaging
资金
- Department of Electronics and Information Technology, Government of India [5(9)/2012-NANO (Vol. II)]
- CSIR [09/731(0115)/2011-EMR-I, 09/731(0105)/2010-EMR-I]
We report the synthesis of a magnetofluorescent biocompatible nanoprobe- following room temperature complexation reaction between Fe(3)o(4)-ZnS nanocomposite and 8-hydroxyquinoline (HQ). The composite nanoprobe exhibited high luminescence quantum yield, low rate of photobleaching, reasonable excited-state lifetime, luminescence stability especially in human blood serum, superparamagnetism and no apparent cytotoxicity. Moreover, the nanoprobe could be used for spatio-controlled cell labeling in the presence of an external magnetic field. The ease of synthesis and cell labeling in vitro make it a suitable candidate for targeted bioimaging applications.
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