期刊
CURRENT OPINION IN BIOTECHNOLOGY
卷 53, 期 -, 页码 201-208出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.copbio.2018.02.002
关键词
-
资金
- ARPA-E [DE-AR0000457]
- Department of Energy [DE-SC0015814]
- Department of Energy, Office of Science (BER)
- U.S. Department of Energy (DOE) [DE-SC0015814] Funding Source: U.S. Department of Energy (DOE)
One-carbon substrates have generated increasing attention as long-term sustainable feedstocks for biobased production of fuels and chemicals. However, their physicochemical properties present significant biological and operational challenges for commercial bioprocesses including kinetically slower substrate activation, high energetic cost of assimilation, low mass transfer, substrate toxicity, and low productivity titers. Several different routes including optimization of native pathways, synthetic pathways, and hybrid methods are being explored to overcome these challenges. Integration of emerging biological solutions with process improvements is enabling faster bioprocess development for cost-effective conversion of one-carbon substrates into fuels and chemicals.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据