Article
Environmental Sciences
Jakub Tomasko, Ondrej Parizek, Jana Pulkrabova
Summary: This study selected clothing as the research object because it is produced in large quantities worldwide and is worn for long periods in direct contact with human skin. Short- and medium-chain chlorinated paraffins (SCCPs and MCCPs) were found in all samples, with higher concentrations in garments with a substantial proportion of synthetic fibers. The effect of washing in the washing machine varied among individual samples.
ENVIRONMENTAL POLLUTION
(2023)
Article
Food Science & Technology
Cheng Li, Zhiqian Liu, Leah Marett, Jennie Pryce, Simone Rochfort
Summary: Milk is a rich source of lipids, and LC-MS is the predominant technique for lipid identification and quantification. However, no standard methods are currently available for the quantification of milk phospholipids. This study aims to examine the factors influencing the quantification outcome of bovine milk phospholipids and discuss the pros and cons of current LC-MS methods.
Article
Chemistry, Applied
Laura Herrero, Jesus E. Quintanilla-Lopez, Mario A. Fernandez, Belen Gomara
Summary: A comprehensive study on packaging used in commercially available milk products from Spanish markets showed that Bisphenol A had the lowest concentration among the tested chemicals. Metallic aluminium bags were found to be the packaging with the lowest migration, while parabens showed the highest levels in fresh-milk samples. The results indicated that the levels of contaminants in Spanish samples were generally lower than those reported in other countries.
Article
Biochemistry & Molecular Biology
Zhiqian Liu, Simone Rochfort
Summary: Regioisomers of triacylglycerols in milk have differential effects on human absorption, but quantifying their ratios remains challenging due to the lack of easy chromatographic separation techniques. This study confirmed the feasibility of using fragment ion intensity ratio to determine regioisomer pairs and demonstrated the ability of C30 stationary phase in resolving interfering isomers. The research proposed a novel algorithm to consider double bond isomers and eliminate interference from isobaric ions, presenting a simple LC-MS method suitable for genetic analysis of milk samples.
Article
Chemistry, Analytical
Yunhan Yu, Mengya Kuang, Baohua Zheng, Meiling Wang, Zhenqiang Liu, Huilan Xu, Jianwu Wang
Summary: An improved method for detecting endocrine-disrupting chemicals in milk using high performance liquid chromatography tandem mass spectrometry is presented. The method is easy, fast, and cost-efficient, and provides a reference for the detection of various endocrine disruptors in milk and other dairy products.
JOURNAL OF SEPARATION SCIENCE
(2022)
Article
Biochemical Research Methods
Brett R. Blackwell, Gerald T. Ankley
Summary: This study developed a method for the simultaneous measurement of thirteen endogenous steroids in small sample volumes without derivatization, validating the concentrations of steroids and demonstrating potential application in aquatic toxicology studies for identifying EDCs.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
(2021)
Article
Medical Laboratory Technology
Songlin Yu, Danchen Wang, Xiaoli Ma, Yuanyuan Zhang, Dandan Sun, Yutong Zou, Jialei Yu, Fang Zhang, Guohua Yang, Shaowei Xie, Qian Cheng, Xinqi Cheng, Ling Qiu
Summary: A LC-MS/MS method was established to quantify G17 and G34 simultaneously, showing high analytical performance. The method was compared with CLIA and RIA, and it was found to be highly correlated with both methods. The study suggests that G17 may be the most specific biomarker for gastrinoma diagnosis.
CLINICAL CHEMISTRY
(2021)
Article
Environmental Sciences
Clemence A. Gely, Marlene Z. Lacroix, Mathieu Morin, Christophe Vayssiere, Veronique Gayrard, Nicole Picard-Hagen
Summary: Regulatory measures and public concerns have led to the replacement of bisphenol A (BPA) in consumer products, but the potential endocrine disruption of BPA alternatives is still under surveillance. This study assessed the placental transfer of 15 selected bisphenols using an ex vivo human placental perfusion model, revealing varying levels of transport efficiency among the bisphenols. The data from this study will be valuable for predicting fetal exposure to these emerging contaminants.
Review
Endocrinology & Metabolism
Yinuo Hou, Yan Gao, Shudi Guo, Zhibin Zhang, Ruibing Chen, Xiangyang Zhang
Summary: Endocrine tumors are highly heterogeneous in function, structure, and embryology. Analyzing molecular alternations within the heterogeneous microenvironment for endocrine tumors remains challenging. Recently, proteomic, lipidomic, and metabolomic platforms have been applied to explore the cellular and molecular mechanisms of tumor genesis, progression, and metastasis. This review discusses the use of mass spectrometry imaging and microextraction to extract proteins precisely from specific regions of endocrine tumors and compares the applications of proteomic, lipidomic, and metabolomic platforms in elucidating cellular and molecular processes involved in endocrine tumors.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Food Science & Technology
Emad Karrar, Isam A. Mohamed Ahmed, Thom Huppertz, Fatih Oz, Wei Wei, Xingguo Wang
Summary: This study characterized the triacylglycerols (TAGs) in milk fat from cow, yak, donkey, goat, and camel using UPLC-Q-TOF-MS. A total of 47, 52, 61, 75, and 87 TAG species were identified in camel, goat, donkey, cow, and yak milk fat, respectively. The most abundant TAG species varied among the different milk fats. This work contributes to a better understanding of TAGs in milk from various species.
INTERNATIONAL DAIRY JOURNAL
(2022)
Article
Chemistry, Applied
Lei Tian, Jingyun Zheng, Marco Pineda, Viviane Yargeau, Daniel Furlong, Jonathan Chevrier, Riana Bornman, Muvhulawa Obida, Cindy Gates Goodyer, Stephane Bayen
Summary: A sensitive method combining ultrasound-assisted liquid extraction with liquid chromatography was used to screen for 18 plastic-related contaminants in food samples from Montreal and South Africa. Bisphenol A, bisphenol S, and seven different plasticizers were detected in various food items from both countries, with some differences in the most frequently detected contaminants.
Article
Environmental Sciences
Daniel Armada, Maria Llompart, Maria Celeiro, Pablo Garcia-Castro, Nuno Ratola, Thierry Dagnac, Jacob de Boer
Summary: This study assessed the presence of organic compounds in fill samples from synthetic turf football pitches, finding carcinogenic substances and endocrine disruptors in most rubber samples, indicating the presence of hazardous substances in recycled crumb rubber on a global scale.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Biochemical Research Methods
Johannes B. Mueller-Reif, Fynn M. Hansen, Lisa Schweizer, Peter Treit, Philipp E. Geyer, Matthias Mann
Summary: Reversed-phase HPLC is commonly used in MS-based proteomics for peptide separation, with particle-packed capillary columns being predominantly used in nanoflow HPLC systems. Despite capillary columns being a standard for many years, they are expensive and have short lifetimes, leading many laboratories to produce their own in-house packed columns.
MOLECULAR & CELLULAR PROTEOMICS
(2021)
Article
Endocrinology & Metabolism
Jiahua Zhang, Ziman Fu, Weiwei Jiang, Yingying Zhang, Yiting Wang, Chunjian Shan
Summary: Breast milk jaundice (BMJ) is common in breastfed newborns, with researchers focusing on peptides in breast milk. By using LC-MS/MS analysis, this study identified 245 peptides in breast milk, with 30 differentially expressed peptides. GO analysis revealed that these peptides may play a role in BMJ pathogenesis.
JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS
(2022)
Article
Agriculture, Multidisciplinary
Ilona Kiszkiel-Taudul, Patrycja Stankiewicz
Summary: The presence of tigecycline residues in food products poses a harmful threat to the health of potential human consumers. To address this, analysts have developed microextraction methods using deep eutectic solvents for efficient isolation of this compound. Liquid-liquid microextraction of tigecycline from milk samples using hydrophobic deep eutectic solvents was successfully carried out, and the extracted tigecycline was analyzed using LC-MS/MS. The developed method exhibited high sensitivity and precision for the determination of tigecycline in different bovine milk samples.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Food Science & Technology
Alastair Ross, Carl Brunius, Olivier Chevallier, Gaud Dervilly, Chris Elliott, Yann Guitton, Jessica E. Prenni, Otto Savolainen, Lieselot Hemeryck, Nanna Hjort Vidkjaer, Nigel Scollan, Sara L. Stead, Renyu Zhang, Lynn Vanhaecke
Summary: The new technology of REIMS shows potential in efficiently detecting safety, quality, and authenticity parameters in meat products. It has been successfully used to identify species fraud, hormone usage, and monitor processing, offering a valuable tool for the meat industry.
Article
Chemistry, Applied
Ratnasekhar Ch, Olivier Chevallier, Philip McCarron, Terence F. McGrath, Di Wu, Le Nguyen Doan Duy, Arun P. Kapil, Mary McBride, Christopher T. Elliott
Summary: The study utilized HS-GC-MS technology to establish a model that can accurately identify rice samples from China, India, and Vietnam, with high discrimination and accuracy.
Article
Water Resources
Y. Xie, H. F. Berntsen, K. E. Zimmer, E. Ropstad, S. Verhaegen, L. Connolly
Summary: This study assessed the adipogenic effects of a POPs mixture modelled on real-life human exposure levels, finding that such exposures may alter adipose tissue development and function, potentially playing a role in the globally increasing escalation of metabolic disorders.
EXPOSURE AND HEALTH
(2022)
Article
Biochemical Research Methods
Jazmin Osorio, Margarita Aznar, Cristina Nerin, Christopher Elliott, Olivier Chevallier
Summary: This study investigated the migration of oligomers from PLA and starch-based biopolymers to food simulants, focusing on the detection of oligomers using advanced techniques. The results demonstrated that ADI techniques are a promising alternative tool for evaluating the safety and legal compliance of food packaging materials.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Applied
Nicholas Birse, Philip McCarron, Brian Quinn, Kimberly Fox, Olivier Chevallier, Yunhe Hong, Ratnasekhar Ch, Christopher Elliott
Summary: Health conscious consumers are increasingly choosing organic foods, but detecting fraud in this area is challenging. Combining DART-MS with a single quadrupole mass spectrometer has shown high accuracy in differentiating organic from conventional vegetables.
Article
Pharmacology & Pharmacy
Ebru Altuntas, Ismaiel A. Tekko, Lalitkumar K. Vora, Narender Kumar, Rebecca Brodsky, Olivier Chevallier, Emma McAlister, Qonita Kurnia Anjani, Helen O. McCarthy, Ryan F. Donnelly
Summary: This study developed a new drug delivery system, bilayer dissolving microneedles array (DMNs) loaded with NES-nanosuspension (NES-NS) to deliver NES intradermally. The results of animal experiments showed that the DMNs successfully delivered NES into the skin and rapidly reached high concentrations, indicating the potential application of this system for on demand hormonal female-controlled pericoital contraception.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2022)
Review
Pharmacology & Pharmacy
Jerrold J. Heindel, Sarah Howard, Keren Agay-Shay, Juan P. Arrebola, Karine Audouze, Patrick J. Babin, Robert Barouki, Amita Bansal, Etienne Blanc, Matthew C. Cave, Saurabh Chatterjee, Nicolas Chevalier, Mahua Choudhury, David Collier, Lisa Connolly, Xavier Coumoul, Gabriella Garruti, Michael Gilbertson, Lori A. Hoepner, Alison C. Holloway, George Howell, Christopher D. Kassotis, Mathew K. Kay, Min Ji Kim, Dominique Lagadic-Gossmann, Sophie Langouet, Antoine Legrand, Zhuorui Li, Helene Le Mentec, Lars Lind, P. Monica Lind, Robert H. Lustig, Corinne Martin-Chouly, Vesna Munic Kos, Normand Podechard, Troy A. Roepke, RobertM. Sargis, Anne Starling, Craig R. Tomlinson, Charbel Touma, Jan Vondracek, Frederick vom Saal, Bruce Blumberg
Summary: Obesity is a multifactorial disease caused by genetic and environmental factors. Overeating and lack of exercise are common causes, but environmental substances known as obesogens can also disrupt the balance of energy intake and expenditure, increasing the risk of obesity. Obesogens primarily affect the development and function of adipose tissue, liver, pancreas, gastrointestinal tract, and brain, altering the control of metabolism. The most sensitive period for obesogen exposure is in utero and early childhood, which may lead to changes in gene expression that can be transmitted to future generations.
BIOCHEMICAL PHARMACOLOGY
(2022)
Correction
Pharmacology & Pharmacy
Jerrold J. Heindel, Sarah Howard, Keren Agay-Shay, Juan P. Arrebola, Karine Audouze, Patrick J. Babin, Robert Barouki, Amita Bansal, Etienne Blanc, Matthew C. Cave, Saurabh Chatterjee, Nicolas Chevalier, Mahua Choudhury, David Collier, Lisa Connolly, Xavier Coumoul, Gabriella Garruti, Michael Gilbertson, Lori A. Hoepner, Alison C. Holloway, George Howell, Christopher D. Kassotis, Mathew K. Kay, Min Ji Kim, Dominique Lagadic-Gossmann, Sophie Langouet, Antoine Legrand, Zhuorui Li, Helene Le Mentec, Lars Lind, P. Monica Lind, Robert H. Lustig, Corinne Martin-Chouly, Vesna Munic Kos, Normand Podechard, Troy A. Roepke, Robert M. Sargis, Anne Starling, Craig R. Tomlinson, Charbel Touma, Jan Vondracek, Frederick vom Saal, Bruce Blumberg
BIOCHEMICAL PHARMACOLOGY
(2022)
Article
Environmental Sciences
Anika Beyer, Paula Schorgg, Nena Karavasiloglou, Sneha Sarwar, Sabine Rohrmann, Till Barnighausen, Aedin Cassidy, Lisa Connolly, Tilman Kuhn
Summary: Phthalate exposure is associated with increased mortality, emphasizing the need for monitoring its impact on health outcomes.
ENVIRONMENTAL RESEARCH
(2022)
Article
Food Science & Technology
Y. Xie, H. F. Berntsen, K. E. Zimmer, E. Ropstad, S. Verhaegen, L. Connolly
Summary: This study found that human exposure to persistent organic pollutants (POPs) may contribute to obesogenic effects. The addition of luteolin, a flavone compound, to a human relevant mixture of POPs in the laboratory was able to inhibit adipocyte formation and intracellular lipid accumulation.
FOOD AND CHEMICAL TOXICOLOGY
(2023)
Article
Multidisciplinary Sciences
Amandine Rousset, Christian Ginies, Olivier Chevallier, Mariano Martinez-Vazquez, Ali Amor, Michel Dorget, Farid Chemat, Sandrine Perino
Summary: This article discusses the applications of guayule resin in adhesives, coatings, pharmaceuticals, etc., and introduces liquid and gas chromatographic analysis methods for analyzing the composition of the resin.
SCIENTIFIC REPORTS
(2023)
Review
Water Resources
Jamie English, Lisa Connolly, Linda D. Stewart
Summary: The intestinal epithelium is the first line of defence against pathogens in the gastrointestinal tract and its structure and function are important for maintaining a healthy gut environment. Tight junction complexes between intestinal epithelial cells play a key role in maintaining the integrity of the gut barrier. Genetic and environmental factors can impact the effectiveness of these tight junction complexes and increase the permeability of the intestine, which has been associated with autoimmune diseases.
EXPOSURE AND HEALTH
(2023)
Article
Toxicology
Emma Harper, Eoin Cunningham, Lisa Connolly
Summary: This study assesses the migration of endocrine disrupting leachates from bio-based polymers used in food packaging development. The results show that most of the tested bio-based polymers and additives did not significantly reduce metabolic activity or hormonal activity. However, some combinations did exhibit estrogenic and anti-androgenic activity, although at much lower levels than traditional petroleum-based plastics. Manipulating additives and formulations alongside toxicological testing can further improve the safety of bio-based packaging alternatives.
FRONTIERS IN TOXICOLOGY
(2022)
Review
Toxicology
Elysia Jewett, Gareth Arnott, Lisa Connolly, Nandini Vasudevan, Eva Kevei
Summary: Biologically active environmental pollutants, such as microplastic and nanoplastic particles, have significant impact on ecosystems, wildlife, and human health. These plastic particles can cause oxidative stress, inflammation, and cellular damage, resulting in reproductive and health issues in animals and humans. However, the full extent of their impact is not yet fully understood, though they carry additional risks through the contaminants and toxic chemicals they transport.
FRONTIERS IN TOXICOLOGY
(2022)
Article
Food Science & Technology
Kelsey Robson, Nicholas Birse, Olivier Chevallier, Christopher Elliott
Summary: Organic food fraud is a significant challenge in the food testing sector, but the use of REIMS system shows promise in detecting various forms of meat fraud with higher accuracy in differentiating organic from conventional beef, rapidly determining the type of meat, and reducing analysis time and costs.
NPJ SCIENCE OF FOOD
(2022)
Article
Food Science & Technology
Ewelina Bigoraj, Iwona Kozyra, Agnieszka Kaupke, Zbigniew Osinski, James Lowther, Artur Rzezutka
Summary: The aim of this study was to assess the prevalence of human enteric viruses in mussels sold on the Polish market and study the fecal contamination of shellfish. The study found that human enteric viruses were commonly present in shellfish, with norovirus being the most frequently detected. The study also observed a seasonal distribution pattern of viruses in shellfish samples.
Editorial Material
Food Science & Technology
Bojan Blagojevic, Lis Alban Denmark
Article
Food Science & Technology
Indy Magnus, Fatemeh Abbasi, Hugo Thienpont, Lien Smeesters
Summary: Food safety and quality are increasingly important in our society, driving the development of novel optical food sensing technologies. However, current optical sensing technologies are often limited in their sensitivity and product variability. In this study, we developed a novel pistachio nut screening methodology using fluorescence spectroscopy and advanced chemometrics to simultaneously detect shells, tree parts, and aflatoxins. By optimizing hardware and software parameters, we achieved a high classification accuracy for healthy pistachio kernels.
Article
Food Science & Technology
Xiaodong Wang, Jingqiang Yu, Haixia Wu, Leiying Wu, Wuyunga Borjihan, Cong Wang, Munkhjargal Burenjargal, Alideertu Dong
Summary: This study developed a novel photon-phonon coupling (PPC) cold sterilization technology and compared its effects with low-temperature pasteurization and microwave ultraviolet. The results showed that PPC effectively reduced bacterial count in raw milk with minimal impact on milk quality and nutritional composition.
Review
Food Science & Technology
Riyadh Abdulmalek Hassan, Sharina Abu Hanifah, Lee Yook Heng, Fawaz Al-badaii, Alizar Ulianas
Summary: This study used bibliometric visualisation map analysis to explore the publication outputs, trends, and hotspots for endocrine disruptors (EDMs) biosensor development in relation to mycotoxins. The analysis showed that the current literature primarily focuses on developing biosensors for detecting highly toxic and widely distributed mycotoxins in food, but there needs to be more focus on biosensors for detecting mycotoxins known as endocrine disruptors.
Article
Food Science & Technology
Yajie Zheng, Jianpeng Dou, Changpo Sun, Hujun Liu, Shipei Zhang, Wenfu Wu
Summary: This study investigated the efficiency of modified SA/ll-glucan/Mt microsphere adsorbents in removing DON and ZEN from CSL. The microspheres showed high adsorption capacity, and simple and rapid regeneration was achieved without affecting the removal efficiency of mycotoxins from CSL.
Article
Food Science & Technology
Carlos Adelantado, Jose Angel Salatti-Dorado, Carlos Herrera, Lourdes Arce, Maria Jose Cardador
Summary: High-performance-ion mobility spectrometry (HPIMS) was used for the first time in the analysis of olive oil samples, following a simple liquid-liquid extraction procedure. The developed methodology is user-friendly, fast, and inexpensive, complying with the principles of green chemistry. The proposed approach, combined with multivariate analysis, showed potential in classifying olive oil samples based on their organoleptic quality, with high accuracy rates.
Article
Food Science & Technology
Jia-Wen Wei, Jia-Rong He, Shi-Yi Chen, Yi-Han Guo, Xuan-Zhu Huo, Nuan Zheng, Shuo-Hui Cao, Yao-Qun Li
Summary: Polycyclic aromatic hydrocarbons (PAHs) are a major cause of human cancer. This study developed a quantitative analysis method for PAH4 using the back propagation neural network (BPNN) algorithm and constant wavelength synchronous fluorescence (CWSF) spectra as the data sets. The method can predict the concentrations of PAH4 in edible oil samples without preprocessing or pre-separation. It has been proven to be a powerful tool for the rapid detection of PAH4.
Article
Food Science & Technology
Liyun Chen, Xiumei Li, Jingyi Chen, Ranxun Lin, Yuhan Mai, Yuxin Lin, Guodong Wang, Zheng Chen, Wei Zhang, Jiang Wang, Cai Yuan, Longguang Jiang, Peng Xu, Mingdong Huang
Summary: Food spoilage is primarily caused by microbial contamination. Curcumin has shown moderate antimicrobial activity as a food preservative. This study formulates curcumin with zinc acetate to enhance its efficacy, resulting in Cur-Zn with increased antimicrobial activity against multiple food-contaminating bacteria and fungi. With light illumination, the antimicrobial activity of Cur-Zn is further enhanced due to the photodynamic inactivation (PDI) effect.
Article
Food Science & Technology
Marta Pilar Ortiz-Moriano, Gonzalo Machado-Schiaffino, Eva Garcia-Vazquez, Alba Ardura
Summary: Mislabelling in the global fisheries sector raises concerns about the identity, safety, and sustainability of seafood products. This study examined mislabelling in shrimps and prawns sold in the Spanish market and assessed potential risks of heavy metal ingestion.
Article
Food Science & Technology
Doyeon Kim, Jinwoo Kim, Minsik Kim
Summary: This study demonstrates the enhanced bactericidal activity of engineered lysins fused with amphipathic antimicrobial peptides against Gram-negative bacterium Cronobacter sakazakii. The fusion lysins are capable of disrupting bacterial cells and significantly reducing the risk of infection within a certain range of temperature and pH. Additionally, the study also shows the bactericidal effect of these fusion lysins against other Gram-negative pathogens.
Article
Food Science & Technology
Seul-Ki Park, Kyung-Jin Cho, Du-Min Jo, Young-Mog Kim
Summary: This study presents a new approach for detecting pathogenic Vibrio spp. in contaminated seafood, which combines PCR with a simplified DNA extraction process and pre-culturing step. The method has been validated and shown to be efficient, time-saving, and highly sensitive, offering a potential alternative for improving safety measures in the food industry.
Article
Food Science & Technology
Suwimol Surareungchai, Chaleeda Borompichaichartkul, Chitsiri Rachtanapun, Nutthachai Pongprasert, Pongphen Jitareerat, Varit Srilaong
Summary: This study builds upon previous research and focuses on risk assessment and analysis in the organic salad industry. The results show that previous risk matrix models can be adapted for various raw materials, and preventive control plans can be applied across different aspects of the production process.
Article
Food Science & Technology
Xuan Zhang, Changling Fang, Xiaoyi Lou, Feng Han, Siman Li, Yongfu Shi, Dongmei Huang
Summary: This study aimed to assess the levels of Biogenic amines (BAs) in four common food types in the Chinese market. It was found that cheese and seafood derived product showed higher levels of BAs, and the histamine level in mackerel and yellow rice wine exceeded the limits.
Article
Food Science & Technology
Martina Foschi, Alessandra Biancolillo, Federico Marini, Francesco Cosentino, Francesca Di Donato, Angelo Antonio D'Archivio
Summary: This study aimed to develop a potentially non-destructive and routine-compatible method for the geographical traceability of high-valued Italian chickpeas. By analyzing the spectral information of the outer and inner parts of the kernels, it was found that the spectral analysis of the outer part yielded accurate and reliable results, indicating the possibility of non-destructive authentication.