Hypertension: history and development of established and novel treatments

Achieved diastolic blood pressure and pulse pressure at target systolic blood pressure (120–140 mmHg) and cardiovascular outcomes in high-risk patients: results from ONTARGET and TRANSCEND trials

(2018) Michael Böhm et al.   EUROPEAN HEART JOURNAL

Spironolactone Versus Clonidine as a Fourth-Drug Therapy for Resistant HypertensionNovelty and Significance

(2018) Eduardo M. Krieger et al.   HYPERTENSION

Relationship between Clinic and Ambulatory Blood-Pressure Measurements and Mortality

(2018) José R. Banegas et al.   NEW ENGLAND JOURNAL OF MEDICINE

Proceedings from the 2nd European Clinical Consensus Conference for device-based therapies for hypertension: state of the art and considerations for the future

(2017) Felix Mahfoud et al.   EUROPEAN HEART JOURNAL

Biochemical Screening for Nonadherence Is Associated With Blood Pressure Reduction and Improvement in AdherenceNovelty and Significance

(2017) Pankaj Gupta et al.   HYPERTENSION

Long-Term Follow-Up of Baroreflex Activation Therapy in Resistant Hypertension

(2017) Sebastian Ewen et al.   HYPERTENSION

Systolic Blood Pressure and Biochemical Assessment of AdherenceNovelty and Significance

(2017) Candace D. McNaughton et al.   HYPERTENSION

Sustained Reduction of Blood Pressure With Baroreceptor Activation TherapyNovelty and Significance

(2017) Peter W. de Leeuw et al.   HYPERTENSION

Risk Factors for Nonadherence to Antihypertensive TreatmentNovelty and Significance

(2017) Pankaj Gupta et al.   HYPERTENSION

Central Iliac Arteriovenous Anastomosis for Uncontrolled HypertensionNovelty and Significance

(2017) Melvin D. Lobo et al.   HYPERTENSION

2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines

(2017) Paul K. Whelton et al.   HYPERTENSION

Endovascular baroreflex amplification for resistant hypertension: a safety and proof-of-principle clinical study

(2017) Wilko Spiering et al.   LANCET

Achieved blood pressure and cardiovascular outcomes in high-risk patients: results from ONTARGET and TRANSCEND trials

(2017) Michael Böhm et al.   LANCET

Quarter-dose quadruple combination therapy for initial treatment of hypertension: placebo-controlled, crossover, randomised trial and systematic review

(2017) Clara K Chow et al.   LANCET

Catheter-based renal denervation in patients with uncontrolled hypertension in the absence of antihypertensive medications (SPYRAL HTN-OFF MED): a randomised, sham-controlled, proof-of-concept trial

(2017) Raymond R Townsend et al.   LANCET

The SPYRAL HTN Global Clinical Trial Program: Rationale and design for studies of renal denervation in the absence (SPYRAL HTN OFF-MED) and presence (SPYRAL HTN ON-MED) of antihypertensive medications

(2016) David E. Kandzari et al.   AMERICAN HEART JOURNAL

Adherence to Antihypertensive Treatment and the Blood Pressure–Lowering Effects of Renal Denervation in the Renal Denervation for Hypertension (DENERHTN) TrialClinical Perspective

(2016) Michel Azizi et al.   CIRCULATION

Response to Letter Regarding Article, “Mitomycin-Induced Pulmonary Veno-Occlusive Disease: Evidence From Human Disease and Animal Model”

(2016) Frédéric Perros et al.   CIRCULATION

Global Disparities of Hypertension Prevalence and ControlClinical Perspective

(2016) Katherine T. Mills et al.   CIRCULATION

Renal artery sympathetic denervation: observations from the UK experience

(2016) Andrew S. P. Sharp et al.   Clinical Research in Cardiology

Renal denervation in hypertensive patients not on blood pressure lowering drugs

(2016) Rosa L. De Jager et al.   Clinical Research in Cardiology

Unattended Blood Pressure Measurements in the Systolic Blood Pressure Intervention Trial

(2016) Sverre E. Kjeldsen et al.   HYPERTENSION

Evaluation of Adherence Should Become an Integral Part of Assessment of Patients With Apparently Treatment-Resistant Hypertension

(2016) Elena Berra et al.   HYPERTENSION

Medication adherence and persistence according to different antihypertensive drug classes: A retrospective cohort study of 255,500 patients

(2016) Martin Schulz et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Cardiovascular event rates and mortality according to achieved systolic and diastolic blood pressure in patients with stable coronary artery disease: an international cohort study

(2016) Emmanuelle Vidal-Petiot et al.   LANCET

Blood pressure lowering for prevention of cardiovascular disease and death: a systematic review and meta-analysis

(2016) Dena Ettehad et al.   LANCET

Clinical Value of Ambulatory Blood Pressure: Evidence and Limits

(2015) G. Mancia et al.   CIRCULATION RESEARCH

Effects of catheter-based renal denervation on cardiac sympathetic activity and innervation in patients with resistant hypertension

(2015) Luca Donazzan et al.   Clinical Research in Cardiology

Blood pressure reductions following catheter-based renal denervation are not related to improvements in adherence to antihypertensive drugs measured by urine/plasma toxicological analysis

(2015) Sebastian Ewen et al.   Clinical Research in Cardiology

Proceedings from the European clinical consensus conference for renal denervation: considerations on future clinical trial design: Figure 1

(2015) Felix Mahfoud et al.   EUROPEAN HEART JOURNAL

Agreement Between 24-Hour Salt Ingestion and Sodium Excretion in a Controlled EnvironmentNovelty and Significance

(2015) Kathrin Lerchl et al.   HYPERTENSION

First Report of the Global SYMPLICITY Registry on the Effect of Renal Artery Denervation in Patients With Uncontrolled Hypertension

(2015) M. Bohm et al.   HYPERTENSION

Impact of Lesion Placement on Efficacy and Safety of Catheter-Based Radiofrequency Renal Denervation

(2015) Felix Mahfoud et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Optimum and stepped care standardised antihypertensive treatment with or without renal denervation for resistant hypertension (DENERHTN): a multicentre, open-label, randomised controlled trial

(2015) Michel Azizi et al.   LANCET

Central arteriovenous anastomosis for the treatment of patients with uncontrolled hypertension (the ROX CONTROL HTN study): a randomised controlled trial

(2015) Melvin D Lobo et al.   LANCET

Spironolactone versus placebo, bisoprolol, and doxazosin to determine the optimal treatment for drug-resistant hypertension (PATHWAY-2): a randomised, double-blind, crossover trial

(2015) Bryan Williams et al.   LANCET

A Randomized Trial of Intensive versus Standard Blood-Pressure Control

(2015)   NEW ENGLAND JOURNAL OF MEDICINE

Renal Denervation for the Treatment of Cardiovascular High Risk-Hypertension or Beyond?

(2014) Michael Böhm et al.   CIRCULATION RESEARCH

Sustained Sympathetic and Blood Pressure Reduction 1 Year After Renal Denervation in Patients With Resistant Hypertension

(2014) Dagmara Hering et al.   HYPERTENSION

Predicting out-of-office blood pressure level using repeated measurements in the clinic

(2014) James P. Sheppard et al.   JOURNAL OF HYPERTENSION

European Society of Hypertension practice guidelines for ambulatory blood pressure monitoring

(2014) Gianfranco Parati et al.   JOURNAL OF HYPERTENSION

Effects of blood pressure lowering on outcome incidence in hypertension. 1. Overview, meta-analyses, and meta-regression analyses of randomized trials

(2014) Costas Thomopoulos et al.   JOURNAL OF HYPERTENSION

Blood pressure and incidence of twelve cardiovascular diseases: lifetime risks, healthy life-years lost, and age-specific associations in 1·25 million people

(2014) Eleni Rapsomaniki et al.   LANCET

A Controlled Trial of Renal Denervation for Resistant Hypertension

(2014) Deepak L. Bhatt et al.   NEW ENGLAND JOURNAL OF MEDICINE

From SYMPLICITY HTN-3 to the Renal Denervation Global Registry: where do we stand and where should we go?

(2014) Atul Pathak et al.   EuroIntervention

Salt reduction in England from 2003 to 2011: its relationship to blood pressure, stroke and ischaemic heart disease mortality

(2014) Feng J He et al.   BMJ Open

2013 ESH/ESC Guidelines for the management of arterial hypertension

(2013)   EUROPEAN HEART JOURNAL

Angiotensin-converting enzyme inhibitors reduce mortality in hypertension: a meta-analysis of randomized clinical trials of renin-angiotensin-aldosterone system inhibitors involving 158 998 patients

(2012) L. C. van Vark et al.   EUROPEAN HEART JOURNAL

Uncontrolled and Apparent Treatment Resistant Hypertension in the United States, 1988 to 2008

(2011) Brent M. Egan et al.   CIRCULATION

Addition of Spironolactone in Patients With Resistant Arterial Hypertension (ASPIRANT)

(2011) Jan Václavík et al.   HYPERTENSION

Target Blood Pressure for Treatment of Isolated Systolic Hypertension in the Elderly

(2010) Toshio Ogihara et al.   HYPERTENSION

Novel Baroreflex Activation Therapy in Resistant Hypertension

(2010) Ingrid J.M. Scheffers et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Combination Therapy Versus Monotherapy in Reducing Blood Pressure: Meta-analysis on 11,000 Participants from 42 Trials

(2009) David S. Wald et al.   AMERICAN JOURNAL OF MEDICINE

The 2009 Carl Ludwig Lecture: pathophysiology of the human sympathetic nervous system in cardiovascular diseases: the transition from mechanisms to medical management

(2009) Murray Esler   JOURNAL OF APPLIED PHYSIOLOGY

Calcium channel blockers and cardiovascular outcomes: a meta-analysis of 175 634 patients

(2009) Pierluigi Costanzo et al.   JOURNAL OF HYPERTENSION

Resistant Hypertension: Diagnosis, Evaluation, and Treatment

(2008) David A. Calhoun et al.   CIRCULATION