期刊
CLINICAL CARDIOLOGY
卷 41, 期 2, 页码 185-193出版社
WILEY
DOI: 10.1002/clc.22894
关键词
Coronary Microvascular Dysfunction; Myocardial Infarction; Myocardial Ischemia With No Obstructive Coronary Artery Disease
资金
- National Heart, Lung and Blood Institutes [N01-HV-68161, N01-HV-68162, N01-HV-68163, N01-HV-68164, RO1-HL-073412-01]
- Gustavus and Louis Pfeiffer Research Foundation, Danville, New Jersey [U01-64829, U01-HL649141, U01-HL649241, UL1-TR001427]
- Women's Guild of Cedars-Sinai Medical Center, Los Angeles, California
- Ladies Hospital Aid Society of Western Pennsylvania, Pittsburgh, Pennsylvania
- QMED, Inc., Laurence Harbor, New Jersey
- Edythe L. Broad Endowment, Cedars-Sinai Medical Center, Los Angeles
- Barbra Streisand Women's Cardiovascular Research and Education Program, Cedars-Sinai Medical Center, Los Angeles
- Linda Joy Pollin Women's Heart Health Program, Cedars-Sinai Medical Center, Los Angeles
- Constance Austin Fellowship Endowment, Cedars-Sinai Medical Center, Los Angeles
- Erika Glazer Women's Heart Health Project, Cedars-Sinai Medical Center, Los Angeles, California
The syndromes of myocardial infarction/myocardial ischemia with No Obstructive Coronary Artery Disease (MINOCA/INOCA) are increasingly evident. A majority of these patients have coronary microvascular dysfunction. These patients have elevated risk for a cardiovascular event (including acute coronary syndrome, myocardial infarction, stroke, and repeated cardiovascular procedures) and appear to be at higher risk for development of heart failure with preserved ejection fraction. Terminology such as coronary artery disease or coronary heart disease is often synonymous with obstructive atherosclerosis in the clinician's mind, leaving one at a loss to recognize or explain the phenomenon of MINOCA and INOCA with elevated risk. We review the available literature regarding stable and unstable ischemic heart disease that suggests that use of the ischemic heart disease (IHD) terminology matters for women, and should facilitate recognition of risk to provide potential treatment targets and optimized health.
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