标题
The role of the alternative pathway of complement activation in glomerular diseases
作者
关键词
Alternative pathway of complement activation, Glomerular diseases, C3, Complement factor H
出版物
CLINICAL AND EXPERIMENTAL MEDICINE
Volume 18, Issue 3, Pages 297-318
出版商
Springer Nature
发表日期
2018-02-15
DOI
10.1007/s10238-018-0491-8
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Deletion Variants ofCFHR1andCFHR3Associate with Mesangial Immune Deposits but Not with Progression of IgA Nephropathy
- (2017) Perrine Jullien et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Anti-Factor B and Anti-C3b Autoantibodies in C3 Glomerulopathy and Ig-Associated Membranoproliferative GN
- (2017) Maria Chiara Marinozzi et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Circulating complement factor H–related proteins 1 and 5 correlate with disease activity in IgA nephropathy
- (2017) Nicholas R. Medjeral-Thomas et al. KIDNEY INTERNATIONAL
- Elevated factor H–related protein 1 and factor H pathogenic variants decrease complement regulation in IgA nephropathy
- (2017) Agustín Tortajada et al. KIDNEY INTERNATIONAL
- A novel CFHR1-CFHR5 hybrid leads to a familial dominant C3 glomerulopathy
- (2017) Shambhuprasad K. Togarsimalemath et al. KIDNEY INTERNATIONAL
- C5 nephritic factors drive the biological phenotype of C3 glomerulopathies
- (2017) Maria-Chiara Marinozzi et al. KIDNEY INTERNATIONAL
- Atypical hemolytic uremic syndrome and C3 glomerulopathy: conclusions from a “Kidney Disease: Improving Global Outcomes” (KDIGO) Controversies Conference
- (2017) Timothy H.J. Goodship et al. KIDNEY INTERNATIONAL
- Different types of glomerulonephritis associated with the dysregulation of the complement alternative pathway in 2 brothers
- (2017) Pei Chen et al. MEDICINE
- Complement in ANCA-associated vasculitis: mechanisms and implications for management
- (2017) Min Chen et al. Nature Reviews Nephrology
- The renaissance of complement therapeutics
- (2017) Daniel Ricklin et al. Nature Reviews Nephrology
- Regulator-dependent mechanisms of C3b processing by factor I allow differentiation of immune responses
- (2017) Xiaoguang Xue et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Rare genetic variant in the CFB gene presenting as atypical hemolytic uremic syndrome and immune complex diffuse membranoproliferative glomerulonephritis, with crescents, successfully treated with eculizumab
- (2017) Khalid Alfakeeh et al. PEDIATRIC NEPHROLOGY
- Regulator-dependent mechanisms of C3b processing by factor I allow differentiation of immune responses
- (2017) Xiaoguang Xue et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Decreased Serum C3 Levels in Immunoglobulin A (IgA) Nephropathy with Chronic Kidney Disease: A Propensity Score Matching Study
- (2017) Xi Yang et al. MEDICAL SCIENCE MONITOR
- Factor H-Related (FHR)-1 and FHR-2 Form Homo- and Heterodimers, while FHR-5 Circulates Only As Homodimer in Human Plasma
- (2017) Anna E. van Beek et al. Frontiers in Immunology
- Complement C3 Genotyping of Slow and Fast Variants by Real Time PCR-High Resolution Melting
- (2017) D.M. Valero-Hervás et al. European Journal of Inflammation
- C3 glomerulopathy and current dilemmas
- (2016) Naoko Ito et al. Clinical and Experimental Nephrology
- All Things Complement
- (2016) Joshua M. Thurman et al. Clinical Journal of the American Society of Nephrology
- Update on Lupus Nephritis
- (2016) Salem Almaani et al. Clinical Journal of the American Society of Nephrology
- Treatable renal disease in children with silent lupus nephritis detected by baseline biopsy: association with serum C3 levels
- (2016) Hiroyuki Wakiguchi et al. CLINICAL RHEUMATOLOGY
- Regulators of complement activity mediate inhibitory mechanisms through a common C3b‐binding mode
- (2016) Federico Forneris et al. EMBO JOURNAL
- The complement factor H-related proteins
- (2016) Nicholas Medjeral-Thomas et al. IMMUNOLOGICAL REVIEWS
- Endothelial cells: source, barrier, and target of defensive mediators
- (2016) Lubka T. Roumenina et al. IMMUNOLOGICAL REVIEWS
- Structure of Complement C3(H2O) Revealed By Quantitative Cross-Linking/Mass Spectrometry And Modeling
- (2016) Zhuo A. Chen et al. MOLECULAR & CELLULAR PROTEOMICS
- Familial C3 glomerulonephritis caused by a novel CFHR5-CFHR2 fusion gene
- (2016) Xue Xiao et al. MOLECULAR IMMUNOLOGY
- Complement gene variants determine the risk of immunoglobulin-associated MPGN and C3 glomerulopathy and predict long-term renal outcome
- (2016) Paraskevas Iatropoulos et al. MOLECULAR IMMUNOLOGY
- Complement in disease: a defence system turning offensive
- (2016) Daniel Ricklin et al. Nature Reviews Nephrology
- Alternative Pathway Dysregulation and the Conundrum of Complement Activation by IgG4 Immune Complexes in Membranous Nephropathy
- (2016) Dorin-Bogdan Borza Frontiers in Immunology
- Glomerular Diseases Dependent on Complement Activation, Including Atypical Hemolytic Uremic Syndrome, Membranoproliferative Glomerulonephritis, and C3 Glomerulopathy: Core Curriculum 2015
- (2015) Marina Noris et al. AMERICAN JOURNAL OF KIDNEY DISEASES
- Mapping interactions between complement C3 and regulators using mutations in atypical hemolytic uremic syndrome
- (2015) E. C. Schramm et al. BLOOD
- Relationship of Circulating Anti-C3b and Anti-C1q IgG to Lupus Nephritis and Its Flare
- (2015) D. J. Birmingham et al. Clinical Journal of the American Society of Nephrology
- Molecules Great and Small: The Complement System
- (2015) D. R. Mathern et al. Clinical Journal of the American Society of Nephrology
- Association of Serum C3 Concentration and Histologic Signs of Thrombotic Microangiopathy with Outcomes among Patients with ANCA-Associated Renal Vasculitis
- (2015) L. Manenti et al. Clinical Journal of the American Society of Nephrology
- Functional Characterization of Autoantibodies against Complement Component C3 in Patients with Lupus Nephritis
- (2015) Vasil V. Vasilev et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Anti–Factor H Autoantibodies in C3 Glomerulopathies and in Atypical Hemolytic Uremic Syndrome: One Target, Two Diseases
- (2015) Caroline Blanc et al. JOURNAL OF IMMUNOLOGY
- Factor H–Related Protein 5 Interacts with Pentraxin 3 and the Extracellular Matrix and Modulates Complement Activation
- (2015) Ádám I. Csincsi et al. JOURNAL OF IMMUNOLOGY
- A Familial C3GN Secondary to Defective C3 Regulation by Complement Receptor 1 and Complement Factor H
- (2015) S. Chauvet et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Current Understanding of the Role of Complement in IgA Nephropathy
- (2015) N. Maillard et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Mayo Clinic/Renal Pathology Society Consensus Report on Pathologic Classification, Diagnosis, and Reporting of GN
- (2015) S. Sethi et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- SP137PERSITENT REDUCTION OF SERUM C3 AND LUPUS NEPHRITIS OUTCOME: A RETROSPECTIVE OBSERVATIONAL STUDY
- (2015) Lucio Manenti et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- Plasma complement factor H is associated with disease activity of patients with ANCA-associated vasculitis
- (2015) Su-Fang Chen et al. ARTHRITIS RESEARCH & THERAPY
- Case report: lupus nephritis with autoantibodies to complement alternative pathway proteins and C3 gene mutation
- (2015) Pilar Nozal et al. BMC Nephrology
- A Revised Mechanism for the Activation of Complement C3 to C3b
- (2014) Elizabeth Rodriguez et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Complement Factor B Mutations in Atypical Hemolytic Uremic Syndrome--Disease-Relevant or Benign?
- (2014) M. C. Marinozzi et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Variants in Complement Factor H and Complement Factor H-Related Protein Genes, CFHR3 and CFHR1, Affect Complement Activation in IgA Nephropathy
- (2014) L. Zhu et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Anti-C1q antibodies in systemic lupus erythematosus
- (2014) A-M Orbai et al. LUPUS
- Discovery of new risk loci for IgA nephropathy implicates genes involved in immunity against intestinal pathogens
- (2014) Krzysztof Kiryluk et al. NATURE GENETICS
- Association of Low Serum Complement C3 with Reduced Patient and Renal Survival in Antimyeloperoxidase-Associated Small-Vessel Vasculitis
- (2014) Yair Molad et al. NEPHRON CLINICAL PRACTICE
- C3 nephritic factor can be associated with membranous glomerulonephritis
- (2014) Olivier Niel et al. PEDIATRIC NEPHROLOGY
- C3 Glomerulonephritis Associated With Monoclonal Gammopathy: A Case Series
- (2013) Ladan Zand et al. AMERICAN JOURNAL OF KIDNEY DISEASES
- The Complement Cascade and Renal Disease
- (2013) Katarzyna Kościelska-Kasprzak et al. ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS
- C3 Glomerulopathy: Clinicopathologic Features and Predictors of Outcome
- (2013) N. R. Medjeral-Thomas et al. Clinical Journal of the American Society of Nephrology
- C3 glomerulopathy–associated CFHR1 mutation alters FHR oligomerization and complement regulation
- (2013) Agustín Tortajada et al. JOURNAL OF CLINICAL INVESTIGATION
- Complement factor H–related hybrid protein deregulates complement in dense deposit disease
- (2013) Qian Chen et al. JOURNAL OF CLINICAL INVESTIGATION
- C5a Receptor (CD88) Blockade Protects against MPO-ANCA GN
- (2013) H. Xiao et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- A Candidate Gene Approach to ANCA-Associated Vasculitis Reveals Links to the C3 and CTLA-4 Genes but not to the IL1-Ra And Fcγ-RIIa Genes
- (2013) Ulf Persson et al. KIDNEY & BLOOD PRESSURE RESEARCH
- C3 glomerulopathy: consensus report
- (2013) Matthew C. Pickering et al. KIDNEY INTERNATIONAL
- Complement C3 and its polymorphism: biological and clinical consequences
- (2013) Joris R. Delanghe et al. PATHOLOGY
- Dimerization of complement factor H-related proteins modulates complement activation in vivo
- (2013) E. Goicoechea de Jorge et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Complement in ANCA-Associated Vasculitis
- (2013) J. Charles Jennette et al. SEMINARS IN NEPHROLOGY
- The Role of Complement in Membranous Nephropathy
- (2013) Hong Ma et al. SEMINARS IN NEPHROLOGY
- How anti-neutrophil cytoplasmic autoantibodies activate neutrophils
- (2012) R. Kettritz CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Factor H-related Protein 4 Activates Complement by Serving as a Platform for the Assembly of Alternative Pathway C3 Convertase via Its Interaction with C3b Protein
- (2012) Mario Hebecker et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Combination of Factor H Mutation and Properdin Deficiency Causes Severe C3 Glomerulonephritis
- (2012) A. M. Lesher et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- A Hybrid CFHR3-1 Gene Causes Familial C3 Glomerulopathy
- (2012) T. H. Malik et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Loss of Properdin Exacerbates C3 Glomerulopathy Resulting from Factor H Deficiency
- (2012) M. M. Ruseva et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Acquired and genetic complement abnormalities play a critical role in dense deposit disease and other C3 glomerulopathies
- (2012) Aude Servais et al. KIDNEY INTERNATIONAL
- Sensitive and specific assays for C3 nephritic factors clarify mechanisms underlying complement dysregulation
- (2012) Danielle Paixão-Cavalcante et al. KIDNEY INTERNATIONAL
- Circulating complement activation in patients with anti-neutrophil cytoplasmic antibody–associated vasculitis
- (2012) Shen-Ju Gou et al. KIDNEY INTERNATIONAL
- The investigation of allele and genotype frequencies of human C3 (rs2230199) in south Iranian population
- (2012) Najmeh Bazyar et al. MOLECULAR BIOLOGY REPORTS
- Proliferative Glomerulonephritis Secondary to Dysfunction of the Alternative Pathway of Complement
- (2011) S. Sethi et al. Clinical Journal of the American Society of Nephrology
- Allelic Variants of Complement Genes Associated with Dense Deposit Disease
- (2011) M. A. Abrera-Abeleda et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Genome-wide association study identifies susceptibility loci for IgA nephropathy
- (2011) Ali G Gharavi et al. NATURE GENETICS
- Association of Genetic Variants in Complement Factor H and Factor H-Related Genes with Systemic Lupus Erythematosus Susceptibility
- (2011) Jian Zhao et al. PLoS Genetics
- Dense Deposit Disease Associated With Monoclonal Gammopathy of Undetermined Significance
- (2010) Sanjeev Sethi et al. AMERICAN JOURNAL OF KIDNEY DISEASES
- The complement system
- (2010) J. Vidya Sarma et al. CELL AND TISSUE RESEARCH
- Molecular analysis of C3 allotypes in patients with nephritic factor
- (2010) J. E. FINN et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Human C3 mutation reveals a mechanism of dense deposit disease pathogenesis and provides insights into complement activation and regulation
- (2010) Rubén Martínez-Barricarte et al. JOURNAL OF CLINICAL INVESTIGATION
- Complement Factor H Deficiency Accelerates Development of Lupus Nephritis
- (2010) L. Bao et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Clinical Features of Anti-Factor H Autoantibody-Associated Hemolytic Uremic Syndrome
- (2010) M.-A. Dragon-Durey et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Identification of a mutation in complement factor H-related protein 5 in patients of Cypriot origin with glomerulonephritis
- (2010) Daniel P Gale et al. LANCET
- C3 glomerulopathy: a new classification
- (2010) Fadi Fakhouri et al. Nature Reviews Nephrology
- IgG subclasses and complement pathway in segmental and global membranous nephropathy
- (2010) Yoshie Segawa et al. PEDIATRIC NEPHROLOGY
- Structures of C3b in Complex with Factors B and D Give Insight into Complement Convertase Formation
- (2010) F. Forneris et al. SCIENCE
- Properdin: Emerging Roles of a Pattern-Recognition Molecule
- (2009) Claudia Kemper et al. Annual Review of Immunology
- Complement and its role in innate and adaptive immune responses
- (2009) Jason R Dunkelberger et al. CELL RESEARCH
- The heritability and genetics of complement C3 expression in UK SLE families
- (2009) B Rhodes et al. GENES AND IMMUNITY
- The disease-protective complement factor H allotypic variant Ile62 shows increased binding affinity for C3b and enhanced cofactor activity
- (2009) A. Tortajada et al. HUMAN MOLECULAR GENETICS
- The complement system in systemic autoimmune disease
- (2009) Min Chen et al. JOURNAL OF AUTOIMMUNITY
- Structural and functional implications of the alternative complement pathway C3 convertase stabilized by a staphylococcal inhibitor
- (2009) Suzan H M Rooijakkers et al. NATURE IMMUNOLOGY
- Structure of complement fragment C3b–factor H and implications for host protection by complement regulators
- (2009) Jin Wu et al. NATURE IMMUNOLOGY
- 3D structure of the C3bB complex provides insights into the activation and regulation of the complement alternative pathway convertase
- (2009) Eva Torreira et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- C3 deposition glomerulopathy due to a functional Factor H defect
- (2008) Sandra Habbig et al. KIDNEY INTERNATIONAL
- Complement deposition in renal histopathology of patients with ANCA-associated pauci-immune glomerulonephritis
- (2008) M. Chen et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- Association of polymorphisms in complement component C3 gene with susceptibility to systemic lupus erythematosus
- (2008) H. Miyagawa et al. RHEUMATOLOGY
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started