Article
Pediatrics
Lilin Huang, Shumei Peng, Ronghan Li, Dongping Huang, Danyu Xie
Summary: Resmethrin, a type I pyrethroid insecticide, can cause neurotoxicity in both mammals and insects by activating sodium channels. The possible routes of poisoning include inhalation, dermal contact, and ingestion. This fatal case of resmethrin poisoning in a 26-month-old child highlights the importance of immediate diagnosis and treatment to prevent fatalities caused by this type of insecticide.
FRONTIERS IN PEDIATRICS
(2021)
Article
Medicine, Legal
Lihua Zhang, Yingmin Li, Li Wang, Shengnan Zhang, Guozhong Zhang, Min Zuo, Weibo Shi, Bin Cong
Summary: Formaldehyde is a colorless irritating gas often stored in liquid form. It is used as an antiseptic and disinfectant in biology and medicine. This article reports a case of death caused by accidentally drinking formaldehyde solution, confirming the harmful effects of formaldehyde on human systems. Anatomical examination and toxicity tests revealed the concentration of formaldehyde in the blood and gastric tissue, which were consistent with formaldehyde poisoning.
INTERNATIONAL JOURNAL OF LEGAL MEDICINE
(2022)
Review
Medicine, Research & Experimental
Shih-Chun Chien, Shih-Chao Chien, Yu-Jang Su
Summary: Ingestion of chlorfenapyr can lead to severe poisoning or even death, with uncertain toxic effects and mechanisms. It is noteworthy that patients may not have significant abnormalities in the early stages, but fever and deterioration of consciousness may serve as warning signs for fatal outcomes.
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
(2022)
Article
Medicine, General & Internal
Sung Hoon Mun, Gwan Jin Park, Ji Han Lee, Young Min Kim, Hyun Seok Chai, Sang Chul Kim
Summary: This article reports two cases of severe methemoglobinemia caused by intentional exposure to sodium nitrite. The male patient died while the female patient's symptoms resolved after treatment.
Article
Emergency Medicine
Sam Ontiveros, Lee Cantrell
Summary: The intentional misuse of over-the-counter combination cold products, particularly among adolescents, has been widely recognized as a significant issue. This article reports a case of an adolescent decedent with markedly elevated postmortem chlorpheniramine and dextromethorphan blood concentrations and no other identifiable cause of death.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2022)
Article
Environmental Sciences
Karina Sommerfeld-Klatta, Wiktoria Jiers, Magdalena Lukasik-Glebocka, Artur Tezyk, Klaudia Dolinska-Kaczmarek, Kamil Walter, Pawel Swiderski, Szymon Rzepczyk, Barbara Zielinska-Psuja, Czeslaw Zaba
Summary: In recent years, the administration of fentanyl in transdermal drug delivery systems for chronic pain treatment has increased significantly. This study presents three cases of fentanyl poisonings, including two deaths, due to abuse of transdermal fentanyl delivery systems. The various routes of administration and toxic effects highlight the potential dangers of fentanyl in transdermal drug delivery systems.
Article
Gastroenterology & Hepatology
Shiqin Xu, Jinsong Wu, Ying Jin, Liyin Ji, Xuan Zou, Qinghua Hu, Tiejian Feng, Shuang Wu, Yixiang Jiang, Qiongcheng Chen, Huiqun Lu, Shuxiang Qiu, Huaisheng Chen, Min Jiang, Rui Cai, Yaqun Qiu, Xiaolu Shi
Summary: This article reports a case of a patient who died from V. vulnificus infection after consuming oysters at a restaurant. The study found V. vulnificus contamination in the seafood from both the restaurant and the supplier. Whole genome sequencing revealed that the strain isolated from the patient was distantly related to other strains and had higher virulence.
Article
Emergency Medicine
Hao-Cho Ou, Jou-Fang Deng, Chen-Chang Yang, Chin-Sheng Lin, Yan-Chiao Mao, Shih-Hung Tsai, Cheng-Hsuan Ho
Summary: This article reports a case of an 18-year-old male who attempted suicide with a high dose of pure caffeine powder. The patient was successfully rescued through the administration of labetalol and hemodialysis. The article discusses the clinical symptoms, management, and toxicodynamics of caffeine poisoning.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2022)
Article
Medicine, Legal
Muge Gulen, Salim Satar, Cagdas Ince
Summary: This article reports a case of severe poisoning and death after ingestion of acetamiprid. Despite receiving supportive treatment, the patient ultimately died. This suggests that ingesting large amounts of acetamiprid and presenting symptoms late can have fatal consequences.
JOURNAL OF FORENSIC AND LEGAL MEDICINE
(2022)
Article
Public, Environmental & Occupational Health
Lihua Lin, Yuning Wang, Henghui He, Xiang Liu, Min Jiang, Zehao Li, Lianjie Li, Qian Liu
Summary: This retrospective analysis examined fatal intoxication cases from 2009 to 2021 at the Tongji Center for Medicolegal Expertise in Hubei to provide updated information on intoxication patterns. The study aimed to describe important data on intoxication occurrences, improve public safety policies, and assist forensic examiners and police in handling such cases more efficiently. The analysis of 217 cases revealed that deaths from intoxications were more common in males, primarily among individuals aged 30-39. Oral ingestion was the most frequent exposure method. The causative agents of fatal intoxications showed changes compared to the previous decade, with amphetamine overdoses becoming more prevalent and carbon monoxide and rodenticide intoxication declining significantly. Pesticides remained the leading cause of intoxication in 72 cases. Accidental exposure accounted for 60.4% of the deaths, with men more likely to die from accidents and women more likely to commit suicide. The use of succinylcholine, cyanide, and paraquat in homicides requires particular attention.
FRONTIERS IN PUBLIC HEALTH
(2023)
Review
Endocrinology & Metabolism
Azam Erfanifar, Mahsa Mahjani, Sepehr Gohari, Hossein Hassanian-Moghaddam
Summary: This article presents a fatal case of HGH acute toxicity, highlighting the life-threatening complications of HGH misuse.
BMC ENDOCRINE DISORDERS
(2022)
Article
Oncology
Ju-Shao Yen, I-Kuan Wang, Chih-Chia Liang, Jen-Fen Fu, Yi-Chou Hou, Chih-Chun Chang, Po-Wen Gu, Kai-Fan Tsai, Cheng-Hao Weng, Wen-Hung Huang, Ching-Wei Hsu, Tzung-Hai Yen
Summary: Cytokine-mediated inflammation plays a role in paraquat toxicity, with higher levels of certain cytokines observed in non-survivors compared to both healthy controls and survivors. IL-1 beta and MCP-1 could potentially serve as prognostic markers for paraquat poisoning patients.
AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH
(2021)
Article
Medicine, Legal
Jie Zhang, Xiaowei Zhou, Jinghong Ma, Liang Ren, Liang Liu
Summary: This study reports a case of accidental death from DMS poisoning during transportation in a Chinese man. Pathological examination revealed eye irritation and corrosive damage in the respiratory tract, leading to death. A retrospective study of other similar DMS poisoning cases further contributes to our understanding of this type of poisoning.
FORENSIC SCIENCE MEDICINE AND PATHOLOGY
(2023)
Article
Medicine, Legal
F. J. Van Schalkwyk, M. A. Stander, M. Nsizwane, A. Mathee, B-E Van Wyk
Summary: Senecio coronatus, commonly used in traditional medicine in South Africa, does not contain pyrrolizidine alkaloids. Fatal cases of hepatic sinusoidal obstruction syndrome in infants were caused by wrongly identified Senecio species containing large amounts of retrorsine-N-oxide. A validated UPLC-MS/MS method for detecting and quantifying pyrrolizidine alkaloids is described.
FORENSIC SCIENCE INTERNATIONAL
(2021)
Article
Medicine, Legal
Tadashi Nishio, Yoko Toukairin, Tomoaki Hoshi, Tomomi Arai, Makoto Nogami
Summary: This study reported a case of a young woman who died from intentional ingestion of acetone cyanohydrin and the antidepressant citalopram. Autopsy findings showed dependent lividity and mild pulmonary edema. Concentrations of acetone and cyanide were quantified in various body fluids and organs, with similar distributions observed throughout the body.
Article
Oncology
Jogamaya Pattnaik, Smita Kayal, Biswajit Dubashi, Debdatta Basu, K. V. Vinod, H. Nandeesha, Ponraj Madasamy, Ranjith C. S. Kumar, Unni S. Pillai, Naresh Jadhav
SUPPORTIVE CARE IN CANCER
(2020)
Article
Pharmacology & Pharmacy
Rajathi Rajendran, Vivek Kumar Sharma, Hanumanthappa Nandeesha, Ramesh Ananthakrishnan, Kolar Vishwanath Vinod, Senthil Kumar Subramanian
Summary: The study revealed a negative correlation between vascular function and blood glucose levels. Endothelin-1 and vWF abnormalities were observed in individuals with a family history of diabetes and worsened in prediabetes and diabetes. VEGF abnormalities were only found in diabetic individuals.
CLINICAL AND EXPERIMENTAL HYPERTENSION
(2021)
Article
Medicine, General & Internal
Rachana Kannambath, Rakhi Biswas, Jharna Mandal, Kolar V. Vinod, Biswajit Dubashi, Narayanan Parameswaran
Summary: This study aimed to determine the burden and risk factors of CDI among patients with hospital-acquired diarrhea in India. The prevalence of CDI was found to be 18.67%, with prolonged hospital stay being the major risk factor. Addition of GeneXpert for toxin gene detection increased the yield from 12% to 18.68%.
JOURNAL OF LABORATORY PHYSICIANS
(2021)
Article
Medicine, General & Internal
Bhoobalan Magendiran, Augustine Jose, Vinod Kolar Vishwanath, Chanaveerappa Bammigatti
Summary: A 27-year-old woman presented with a variety of symptoms, and was diagnosed with systemic lupus erythematosus and immune-mediated intravascular hemolysis. Symptoms resolved following treatment and there were no further episodes of hemolysis during follow-up.
Article
Cardiac & Cardiovascular Systems
Kumar Inderjeet, Prashant Shankarrao Adole, K. V. Vinod, Ajith Ananthakrishna Pillai
Summary: The present study aimed to assess the diagnostic value of serum netrin-1 and netrin-4 in recognizing acute coronary syndrome (ACS) in patients with type 2 diabetes mellitus (T2DM). It was found that T2DM patients with ACS had lower levels of serum netrin-1 and netrin-4, which were negatively associated with other biochemical markers. ROC analysis showed that netrin-1 and netrin-4 had good sensitivity and specificity for predicting ACS in T2DM patients. Therefore, serum netrin-1 and netrin-4 levels could be considered as complementary markers for ACS diagnosis in T2DM patients.
INDIAN HEART JOURNAL
(2022)
Article
Biochemical Research Methods
Sushmita Bora, Prashant S. Adole, Kolar V. Vinod, Ajith A. Pillai
Summary: Fatty acids play a role in physiological functions and diseases. The optimized GC-IT/MS method allows for the simultaneous quantification of total fatty acids in plasma, providing important information for disease risk prediction, diagnosis, and prognosis.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
(2022)
Article
Medicine, General & Internal
Bayye Rajkumar, Kolar Vishwanath Vinod, Rakhee Kar, Premkumar Ramasubramani
Summary: This study evaluated venom induced consumption coagulopathy (VICC) in viperid envenomation (VE) patients and found that the majority of patients had VICC, with 68% of them experiencing overt bleeding. The 20-min whole blood clotting test (20WBCT) showed good performance in detecting VICC, but false positive results should be considered before deciding on snake antivenom treatment.
JOURNAL OF THE ROYAL COLLEGE OF PHYSICIANS OF EDINBURGH
(2022)
Article
Hematology
Ritwik Dey, Kolar Vishwanath Vinod, Prashant Shankarrao Adole
Summary: The association between body iron stores and the risk of deep vein thrombosis/pulmonary embolism (DVT/PE) among Indian subjects was studied. Anemia and elevated red cell distribution width (RDW) were significantly associated with increased risk of DVT/PE, while iron deficiency was not. These findings suggest that higher iron stores may be a risk factor for DVT/PE.
INDIAN JOURNAL OF HEMATOLOGY AND BLOOD TRANSFUSION
(2023)
Article
Medicine, General & Internal
George M. Varghese, Divya Dayanand, Karthik Gunasekaran, Debasree Kundu, Mukta Wyawahare, Navneet Sharma, Dhruva Chaudhry, Sanjay K. Mahajan, Kavitha Saravu, Blessed W. Aruldhas, Binu S. Mathew, Roshini G. Nair, Nalini Newbigging, Aswathy Mathew, Kundavaram P. P. Abhilash, Manisha Biswal, Ann H. Prasad, Anand Zachariah, Ramya Iyadurai, Samuel G. Hansdak, Sowmya Sathyendra, Thambu D. Sudarsanam, John A. J. Prakash, Abi Manesh, Alladi Mohan, Joel Tarning, Stuart D. Blacksell, Pimnara Peerawaranun, Naomi Waithira, Mavuto Mukaka, Phaik Yeong Cheah, John V. Peter, Ooriapadickal C. Abraham, Nicholas P. J. Day
Summary: This multicenter, double-blind, randomized, controlled trial compared the efficacy of intravenous doxycycline, azithromycin, or a combination of both for the treatment of severe scrub typhus. The results showed that combination therapy was more effective in reducing the occurrence of the primary outcome compared to monotherapy.
NEW ENGLAND JOURNAL OF MEDICINE
(2023)
Article
Endocrinology & Metabolism
Ravindran Ragavi, Prashant Shankarrao Adole, Kolar Vishwanath Vinod, Ajith Ananthakrishna Pillai
Summary: This study found that the expression of ADAM10 in PBMC and serum sRAGE levels were lower in T2DM patients with ACS compared to those without ACS. Serum sRAGE levels and ADAM10 expression were correlated with markers of cardiac injury and glycaemic status. ADAM10 expression and serum sRAGE levels could be used to predict ACS risk and diagnose ACS in T2DM patients.
Article
Urology & Nephrology
Madapathi Sampath Kumar, Kolar Vishwanath Vinod, Nandini Pandit, Vivek Kumar Sharma, Halanaik Dhanapathi, Sreejith Parameswaran
Summary: Delayed gastric emptying (GE) is common among chronic kidney disease (CKD) patients, which may contribute to poor nutritional intake and malnutrition. This study aimed to evaluate the frequency of delayed GE in non-diabetic CKD patients and its correlation with symptoms of gastroparesis, autonomic neuropathy, and nutritional parameters.
INDIAN JOURNAL OF NEPHROLOGY
(2021)
Article
Primary Health Care
Vadivelan Mehalingam, Jayaprakash Sahoo, Zachariah Bobby, Kolar Vishwanath Vinod
JOURNAL OF FAMILY MEDICINE AND PRIMARY CARE
(2020)
Article
Endocrinology & Metabolism
Sushmita Bora, Prashant S. Adole, Nissy Motupalli, Vinay R. Pandit, Kolar V. Vinod
DIABETES & METABOLIC SYNDROME-CLINICAL RESEARCH & REVIEWS
(2020)
Article
Biochemistry & Molecular Biology
Murugaiyan Vasanthi, Prashant Adole, Vinay Pandit, Kolar Vinod
JOURNAL OF MEDICAL BIOCHEMISTRY
(2020)
Article
Endocrinology & Metabolism
K. Midhuna, Prashant S. Adole, Kolar V. Vinod, N. Balamurugan
DIABETES & METABOLIC SYNDROME-CLINICAL RESEARCH & REVIEWS
(2020)
Letter
Emergency Medicine
Zhao-Yu Hsieh, Chen-Xiong Hsu
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Editorial Material
Emergency Medicine
Laura E. Walker, Jessica A. Stanich, Fernanda Bellolio
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Letter
Emergency Medicine
E. Tekin
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Article
Emergency Medicine
Amanda S. Dupont, Patrick S. Walsh
Summary: Recent research indicates that children who unintentionally ingest cannabis often undergo extensive additional testing, such as head imaging or lumbar puncture. However, the yield of these tests is limited. While head imaging and lumbar puncture are frequently performed, diagnoses such as skull fracture, intracranial hemorrhage, intracranial neoplasm, meningitis, or intracranial abscess are rare. Additionally, discharge diagnoses related to other drugs are infrequent. The most common co-diagnoses are cocaine and opioids. Therefore, prompt consideration of cannabis ingestion and quick identification through testing may result in more effective neuroimaging outcomes.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Letter
Emergency Medicine
Mio Nagata, Shunsuke Kudo, Motoyasu Nakamura
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Article
Emergency Medicine
Andy Hung-Yi Lee, Katherine Dickerson Mayes, Regan Marsh, Christina Toledo-Cornell, Eric Goralnick, Michael Wilson, Leon D. Sanchez, Alice Bukhman, Damarcus Baymon, Dana Im, Paul C. Chen
Summary: This study assessed the disparities in transferring patients from an academic medical center emergency department to a community hospital general medical service, revealing healthcare disparities among different patient populations.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Article
Emergency Medicine
Annabelle Croskey, William Trautman, David Barton, Mary Kathleen Ratay, Joshua Shulman
Summary: This case report describes a successful management of ocular palytoxin exposure in a young male, highlighting the importance of prompt recognition and treatment of ocular PTX toxicity.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Article
Emergency Medicine
Matthew K. Kolbeck, Rachel F. Schult, Nicholas Nacca
Summary: This article presents four cases of adolescents who experienced seizures after acute fluoxetine overdose. Although seizures are an uncommon complication after fluoxetine overdose, they occurred in some patients at doses lower than those reported in the literature.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Editorial Material
Emergency Medicine
Daven Patel, John Bailitz, Simone Ymson, Jonas Neichin, Gary D. Peksa, Michael Gottlieb
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Article
Emergency Medicine
Amichai Gutgold, Shaden Salameh, Jeries Nashashibi, Yonatan Gershinsky
Summary: This study aimed to test the prognosis of patients with a pH lower than 6.9 on emergency department admission. The findings showed that a small but significant portion of these patients survived at least 24 hours and until hospital discharge.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Article
Emergency Medicine
Na-Yeon Emily Song, Ki Hong Kim, Ki Jeong Hong
Summary: This study aimed to evaluate the effect of the duration of no-flow (NF) interval on the vaso-pressor effect of initial epinephrine administration in a porcine model of cardiac arrest. The results showed that a shorter NF interval can enhance the vasopressor effect of epinephrine.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Article
Emergency Medicine
Kenneth A. Scheppke, Paul E. Pepe, Jonathan Jui, Remle P. Crowe, Eric K. Scheppke, Nancy G. Klimas, Aileen M. Marty
Summary: This study reported cases of rapid and complete remission of severe long COVID after receiving monoclonal antibody treatment. The findings suggest that monoclonal antibody infusions may be effective in treating severe debilitation caused by long COVID.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Article
Emergency Medicine
Suhrith Bhattaram, Varsha S. Shinde
Summary: Nerve blocks have emerged as promising options for targeted pain relief in the Emergency Department, providing effective analgesia without compromising motor function. The successful use of ultrasound-guided genicular nerve blocks (GNBs) in this case series demonstrates their potential as an alternative to traditional nerve blocks and opioid-based pain control strategies in the ED.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Article
Emergency Medicine
Rick Kye Gan, Jude Chukwuebuka Ogbodo, Yong Zheng Wee, Ann Zee Gan, Pedro Arcos Gonzalez
Summary: The aim of this study was to evaluate and compare the performance of ChatGPT, Google Bard, and medical students in performing START triage during mass casualty situations. The results showed that Google Bard had significantly higher accuracy compared to ChatGPT, while there was no significant difference between Google Bard and medical students.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Article
Emergency Medicine
Nancy Clemens, Paria M. Wilson, Matthew J. Lipshaw, Holly Depinet, Yin Zhang, Michelle Eckerle
Summary: This study compared clinical features and outcomes between pediatric sepsis patients with blood cultures positive versus negative for bacterial pathogens. The results showed that children with blood culture positive sepsis had higher rates of organ dysfunction, a larger base deficit, and higher procalcitonin levels.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)