Article
Chemistry, Inorganic & Nuclear
Fei-Ze Li, Jun-Shan Geng, Kong-Qiu Hu, Ji-Pan Yu, Ning Liu, Zhi-Fang Chai, Lei Mei, Wei-Qun Shi
Summary: By altering the position of carboxylate groups on bipyridinium dicarboxylate, the coordination behavior of uranyl-pseudorotaxane can be significantly influenced, providing an effective regulation approach. Introducing competing counterions and modulating solution acidity can diversely tune the nuclearity of the uranyl center and coordination patterns of the pseudorotaxane ligand, impacting the dimensionality of resultant uranyl compounds. This work demonstrates a feasible method to adjust and control the metal coordination behavior of pseudorotaxane ligands, expanding their potential applications.
INORGANIC CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Martin Dracinsky, Carina Santos Hurtado, Eric Masson, Jiri Kaleta
Summary: Solvent-free mechanochemical synthesis was used to prepare inclusion complexes with cucurbit[7]uril and four model guest molecules. Confirmation of successful formation of individual inclusions was independently confirmed by solid-state NMR techniques and differential scanning calorimetry. Mechanochemical synthesis is an alternative route towards new types of cucurbit[n]uril-guest inclusion complexes.
CHEMICAL COMMUNICATIONS
(2021)
Article
Chemistry, Medicinal
Zhaoxi Sun, Zhe Huai, Qiaole He, Zhirong Liu
Summary: Describing, understanding, and designing complex interaction networks within macromolecular systems remain challenging in modern chemical research. Host-guest systems, despite their relative simplicity in both the structural feature and interaction patterns, still pose problems in theoretical modeling. The barrel-shaped supramolecular container cucurbit[8]uril (CB8) shows promising functionalities in various areas.
JOURNAL OF CHEMICAL INFORMATION AND MODELING
(2021)
Article
Chemistry, Organic
Khaleel Assaf
Summary: The supramolecular complexation of doxepin with cucurbit[7]uril was investigated in aqueous solution, and a host-guest complex was formed. The partial encapsulation of doxepin led to the development of a supramolecular assembly at low concentration.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2022)
Article
Chemistry, Physical
Hugues Lambert, Alvaro Castillo Bonillo, Qiang Zhu, Yong-Wei Zhang, Tung-Chun Lee
Summary: This study computationally explores the modulation of the release kinetics of a guest molecule from the CB7 cavity by ligands binding to the host portal. A correlation between ligand-binding affinity with CB7 and guest residence time is uncovered, allowing for rapid prediction of release kinetics. The study also designs cap-shaped ligand molecules with large binding affinities to significantly boost guest residence times. Notably, halogenated aromatic compounds emerge as top-ranking ligands, and their binding to CB7 is supported by experimental evidence.
NPJ COMPUTATIONAL MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Suresh Moorthy, Alvaro Castillo Bonillo, Hugues Lambert, Elina Kalenius, Tung-Chun Lee
Summary: A new supramolecular approach has been reported to selectively deactivate the electrophilic alpha-carbon of phenyl diazonium ion through host-guest complexation, thus avoiding undesirable side reactions. This method holds great potential for the reactive chemistry of organic molecules in aqueous media.
CHEMICAL COMMUNICATIONS
(2022)
Article
Chemistry, Physical
Valya Nikolova, Anita Velinova, Stefan Dobrev, Nikoleta Kircheva, Silvia Angelova, Todor Dudev
Summary: The interactions between neutral/protonated mitoxantrone and cucurbit[n]uril (n = 7, 8) host systems were analyzed using density functional theory calculations. It was found that stable inclusion complexes can form between doubly and quadruply charged mitoxantrone molecules and CB[7] or CB[8] in a water solvent. Both CB[7] and CB[8] show properties that are useful for drug delivery.
JOURNAL OF PHYSICAL CHEMISTRY A
(2021)
Article
Chemistry, Multidisciplinary
Xin Huang, Hang Zhou, Rong Jiao, Hanrui Liu, Changfu Qin, Lixin Xu, Yueyue Chen
Summary: Supramolecular chemotherapy is an effective strategy to improve the therapeutic efficacy of traditional chemotherapy. The study showed that a supramolecular platform based on cucurbit[7]uril and heptaplatin had higher antitumor activity against colorectal tumors with lower cytotoxicity to normal cells. These findings are expected to advance supramolecular chemotherapy in clinical development.
Article
Chemistry, Analytical
Liqiao Hu, Ming Lei, Jingjing Zhang, Yongping Dong
Summary: In this study, a competitive host-guest interaction was used to develop an off-on-off mode sensor based on ECL, for the quantitative detection of amantadine. Under optimal conditions, the sensor showed a good detection range and limit for amantadine, with outstanding specificity and accuracy.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Physical
Aurica Farcas, Hadjer Ouldali, Comeliu Cojocaru, Manuela Pastoriza-Gallego, Ana -Maria Resmerital, Abdelghani Oukhaled
Summary: A multi-technique approach was used to prepare and characterize poly(3,4-ethylenedioxythiophene/cucurbit[7]uril) pseudorotaxanes (PEDOT.CB7-PPs). By combining computational modeling and experimental validation, strong interactions between PEDOT-CB7-PPs and the aerolysin nanopore were identified. This study provides valuable insights into the interactions between CB7-based supramolecular complexes and biological entities.
Review
Chemistry, Multidisciplinary
Shengke Li, Yan Gao, Yuanfu Ding, Anni Xu, Huaping Tan
Summary: Cucurbit[n]urils (CB[n]s) have emerged as promising building blocks for supramolecular nano drug delivery systems (SNDDS), showing stimuli responsiveness towards various stimuli for drug release. Recent breakthroughs in direct functionalization of CB[n]s have provided feasible methods for preparing superior derivatives for multifunctional SNDDS.
CHINESE CHEMICAL LETTERS
(2021)
Article
Chemistry, Multidisciplinary
Sebastian Almendras, Ana Maria Zarate, Luis Dinamarca-Villarroel, Daniel Guerra, Denis Fuentealba, Jose M. Eltit, Margarita E. Aliaga, Angelica Fierro, Edwin G. Perez
Summary: This study investigated the supramolecular binding behavior of APP(+) and CB[7] in aqueous solution, as well as their cytotoxic effects on HEK293 cells. The results demonstrate that CB[7] can protect cells from the cytotoxicity of APP(+) by forming a complex that reduces the harmful impact of APP(+) on the cells.
NEW JOURNAL OF CHEMISTRY
(2022)
Article
Biochemical Research Methods
Carlos Redondo-Gomez, Soraya Padilla-Lopategui, Alvaro Mata, Helena S. Azevedo
Summary: The host-guest-mediated PA hydrogelation method relies on the formation of a host-guest homoternary complex with CB[8] and aromatic amino-acid-bearing PA nanofibers, resulting in hierarchical morphologies and increased stiffness compared to ion-based equivalents. This alternative cross-linking method can upgrade the design of PA materials and extend their biomedical applications, while maintaining similar biocompatibilities between the new and conventional hydrogels.
BIOCONJUGATE CHEMISTRY
(2022)
Article
Chemistry, Organic
Tianci He, Xianchen Hu, Simin Liu
Summary: An iminium dication 1 was designed as an easily removable guest for CB[7], showing high affinity (K-a > 10(11) M-1) due to optimized ion-dipole interactions and packing coefficient. Under alkaline conditions, 1 in CB[7]center dot 1 is hydrolyzed into 2,6-adamantanedione and pyrrolidine, which can be fully removed by further extraction, enabling the recycling of CB[7] materials.
Article
Chemistry, Multidisciplinary
Shang-Wei Yuan, Pei-Hui Shan, Mao-Xiao Yang, Pei-Hua Ma, Timothy J. Prior, Carl Redshaw, Gang Wei, Zhu Tao, Xin Xiao
Summary: In this study, the host-guest inclusion complexes formed by the symmetric tetramethyl-substituted cucurbit[6]uril with glycine were investigated under different conditions. The interactions were studied in solution and in the solid state, and two molecular structures were reported.
Article
Chemistry, Multidisciplinary
Qian Wu, Yubo Cui, Guifeng Xia, Jinlong Yang, Shuming Du, Xinhong Xiong, Li Yang, Dong Xu, Xu Deng, Jiaxi Cui
Summary: Passive daytime radiative cooling (PDRC) technology, while promising for global spacing cooling, faces limitations in practical application due to reduced cooling effectiveness caused by wear and dirt contamination. Researchers have developed a renewable armor structure using fluorinated hollow glass microspheres to enhance the anti-fouling and cooling properties of PDRC coatings. The coatings exhibit high solar reflectance and thermal emittance, leading to significant temperature reduction below ambient temperature.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Qiang Bei, Bei Zhang, Kaifeng Wang, Shiming Zhang, Guichuan Xing, Clement Cabanetos
Summary: The power conversion efficiency (PCE) of organic solar cells (OSCs) has reached 20% in recent years, thanks to the advantages of organic photoactive materials. Benzothiadiazole (BT) has attracted significant research attention as a building block of OSCs. OSCs based on BT structure have shown diversity, and the increasing PCE values indicate a promising future for OSCs. This review analyzes the progress made in the last decades, focusing on effective BT small-molecules and BT polymers for OSCs. The structure-property relationships, donor-acceptor matching criteria, and morphology control approaches are discussed. The remaining challenges and a personal perspective on the future advancement of OSCs are summarized.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Rong He, Dandan Tang, Ningge Xu, Heng Liu, Kun Dou, Xuejun Zhou, Fabiao Yu
Summary: Nasopharyngeal carcinoma (NPC) is a common malignant tumor of the head and neck, with a high incidence in China and Southeast Asian countries. In this study, a novel near-infrared fluorescent probe, SNAFL-GSH, was designed and synthesized for the detection of glutathione (GSH). The probe showed selective detection of GSH and the ability to distinguish normal and cancer cells. It has great potential for application in the diagnosis and evaluation of NPC.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Zhukang Guo, Baijiang Jin, Yile Fang, Lian Jin, Song Li, Yan Deng, Zhu Chen, Hui Chen, Yuanying Zhang, Rabia Usman, Nongyue He
Summary: This study isolated primary cells that can be stably passaged from spontaneous tumors of genetically engineered pancreatic ductal adenocarcinoma model mice and used an autonomously developed automated screening instrument for efficient nucleic acid aptamer screening. The obtained aptamers were affinity verified at the cellular level. The study also investigated the impact of cell growth environment difference on the recognition ability of aptamers and confirmed the targeting ability and drug loading ability of the aptamer.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Zhongshan Yang, Qiqi Zhang, Hui Song, Xin Chen, Jiwei Cui, Yanhui Sun, Lequan Liu, Jinhua Ye
Summary: Methane chemistry is a significant area of research in catalysis. Converting methane into value-added chemicals is desirable but challenging due to its high C-H bonding energy and lack of pi bonding or unpaired electrons. Photocatalytic partial oxidation of methane to liquid oxygenates is a promising technology for achieving high efficiency and selectivity under mild conditions. The choice and activation of oxidants are crucial for its performance.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Peng Shan, Jing Liao, Jiayi Li, Chengyan Wang, Jie Zhou, Linqiang Mei, Yunlu Dai, Qiang Wang, Wenyan Yin
Summary: This study reports an oral radioprotectant Gel@GYY that combines a gelatin-based hydrogel and a pH-responsive hydrogen sulfide donor. Gel@GYY has excellent adhesion and sustained release properties, allowing it to release H2S in the gastrointestinal tract and effectively scavenge free radicals induced by radiation. It also reduces inflammation and has biodegradable properties.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Lu Liu, Ziyi Liu, Jingnan Cui, Guiling Ning, Weitao Gong
Summary: The development of new metal-free heterogeneous catalysts has been the subject of extensive research. In this study, a new Troger's base (TB)-derived porous organic polymer (POPs) was designed and prepared by integrating multifunctional monomers. The resulting polymer, which combines the advantages of pillar[5]arene macrocycle and TB moiety, exhibited enhanced catalytic performance in Knoevenagel condensation and CO2 conversion, serving as an effective metal-free catalyst. This work provides a new strategy for fabricating metal-free heterogeneous catalysts based on macrocyclic POPs.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Leyong Zhou, Changyin Yang, Weitao Dou, Tongxia Jin, Haibo Yang, Lin Xu
Summary: This review summarizes the application of micro/nanofluidic techniques in constructing supramolecular assemblies of different scales, and highlights the advantages of these techniques over conventional synthesis methods. Furthermore, it emphasizes the potential of micro/nanofluidic systems in improving our understanding of supramolecular self-assembly processes.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Yanchao Jin, Suixiaochen Chen, Peiwen Huang, Xiongjian Chen, Chun-Yan Lin, Li-Ping Li, Xiao Chen, Rui Ding, Jianxi Liu, Riyao Chen
Summary: In this study, magnesium and coconut shell carbon were used to disinfect water by adsorbing copper(II) and converting dissolved oxygen to hydrogen peroxide through Mg corrosion. The copper was enriched on the carbon surface and efficiently catalyzed the hydrogen peroxide to inactivate E.coli. The process showed promising disinfection performance both in laboratory experiments and real wastewater treatment.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Haihong Lai, Zehong Chen, Hao Zhuo, Yijie Hu, Xuan Zhao, Jiwang Yi, Hongzhi Zheng, Ge Shi, Yifan Tong, Ling Meng, Xinwen Peng, Linxin Zhong
Summary: By altering the pyrolysis route of cellulose nanofiber, the structural defects of carbon aerogels can be reduced, leading to improved compressibility and stress retention, as well as higher stress sensor sensitivity and temperature coefficient.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Lina Guo, Jinsong Ding, Wenhu Zhou
Summary: Bacteria-based tumor therapy has resurfaced due to the revolution of tumor immunotherapy, offering unique solutions for traditional tumor treatments. Bacteria with active tropism can selectively colonize tumor sites and suppress tumor growth through various mechanisms, making them attractive tools for tumor treatment. This critical review introduces recent advances in bacteria-based tumor therapy, including bacterial properties, their benefits for tumor therapy, anti-tumor mechanisms, challenges, and future perspectives.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Lan Liang, Chuanbin Wang, Xukai Lu, Yunan Sun, Beibei Yan, Ning Li, Guanyi Chen, Li'an Hou
Summary: This study investigates the interactions between phenol and benzaldehyde in the ECH process through experiments and theoretical calculations. The results show that phenol can accelerate the conversion of benzaldehyde, while benzaldehyde inhibits the conversion of phenol. The research provides a theoretical basis for the application of ECH in practical bio-oil upgrading.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Pengcheng Fan, Yuhao He, Junan Pan, Ning Sun, Qiyu Zhang, Chen Gu, Kang Chen, Weinan Yin, Longlu Wang
Summary: This study focuses on the recent progress in hydrogen evolution reaction (HER) based on photothermal effect. It introduces the main pathways of photothermal conversions applied in H2 evolution, summarizes the functions of the photothermal effect, and presents a method to improve the catalytic system through thermal means. The study also discusses the challenges and outlook in this promising area.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Leiduo Lai, Hongyu Zhou, Yichen Hong, Mengfan Luo, Yang Shi, Heng Zhang, Zhaokun Xiong, Gang Yao, Bo Lai
Summary: In this study, a facile ammonia reduction strategy was proposed and a novel FeVO3-x catalyst was synthesized for the activation of peroxymonosulfate (PMS) to degrade the pharmaceutical carbamazepine (CBZ). The results showed that the system could rapidly degrade CBZ and generate various active species involved in the degradation process.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Tangxin Xiao, Xiuxiu Li, Liangliang Zhang, Kai Diao, Zheng-Yi Li, Xiao-Qiang Sun, Leyong Wang
Summary: This study presents the construction of a supramolecular light harvesting system based on sequential energy transfer. The system demonstrates tunable fluorescence emission through self-assembly of polymers into nanoparticles, achieving efficient two-step light harvesting.
CHINESE CHEMICAL LETTERS
(2024)
