CoIII -Catalyzed Isonitrile Insertion/Acyl Group Migration Between C−H and N−H bonds of Arylamides

Amides as Weak Coordinating Groups in Proximal C-H Bond Activation

(2017) Riki Das et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Cobalt(II)-Catalyzed Isocyanide Insertion Reaction with Sulfonyl Azides in Alcohols: Synthesis of Sulfonyl Isoureas

(2017) Tian Jiang et al.   JOURNAL OF ORGANIC CHEMISTRY

Cobalt-Catalyzed Annulation of Amides with Isocyanides via C(sp2)–H Activation

(2017) Zheng-Yang Gu et al.   JOURNAL OF ORGANIC CHEMISTRY

Mechanistic Basis for Efficient, Site-Selective, Aerobic Catalytic Turnover in Pd-Catalyzed C–H Imidoylation of Heterocycle-Containing Molecules

(2017) Stephen J. Tereniak et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

C–H and N–H Bond Annulation of Benzamides with Isonitriles Catalyzed by Cobalt(III)

(2017) Basker Sundararaju et al.   SYNTHESIS-STUTTGART

An efficient synthesis of iminoisoindolione derivatives by cobalt-catalyzed oxidative isocyanide insertion

(2017) Feihua Zou et al.   TETRAHEDRON

Cobalt-Catalyzed sp2 -C−H Activation: Intermolecular Heterocyclization with Allenes at Room Temperature

(2016) Neetipalli Thrimurtulu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Simple and Versatile Amide Directing Group for C−H Functionalizations

(2016) Ru-Yi Zhu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Overcoming the Limitations of C−H Activation with Strongly Coordinating N-Heterocycles by Cobalt Catalysis

(2016) Hui Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The medicinal chemist's toolbox for late stage functionalization of drug-like molecules

(2016) Tim Cernak et al.   CHEMICAL SOCIETY REVIEWS

Nickel-Catalyzed Oxidative C−H/N−H Isocyanide Insertion: An Efficient Synthesis of Iminoisoindolinone Derivatives

(2016) Wenyan Hao et al.   Chemistry-An Asian Journal

Pd-Catalyzed α-Selective C–H Functionalization of Olefins: En Route to 4-Imino-β-Lactams

(2016) Wei-Jun Kong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Unveiling Secrets of Overcoming the “Heteroatom Problem” in Palladium-Catalyzed Aerobic C–H Functionalization of Heterocycles: A DFT Mechanistic Study

(2016) Yanfeng Dang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Modern advances in heterocyclic chemistry in drug discovery

(2016) Alexandria P. Taylor et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Switch to Allylic Selectivity in Cobalt-Catalyzed Dehydrogenative Heck Reactions with Unbiased Aliphatic Olefins

(2016) Soham Maity et al.   ACS Catalysis

Cobalt(II)-Catalyzed C sp 2H Alkynylation/Annulation with Terminal Alkynes: Selective Access to 3-Methyleneisoindolin-1-one

(2015) Lin-Bao Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cobalt(III)-Catalyzed Aryl and Alkenyl CH Aminocarbonylation with Isocyanates and Acyl Azides

(2015) Jie Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Metal-Mediated and Metal-Catalyzed Reactions of Isocyanides

(2015) Vadim P. Boyarskiy et al.   CHEMICAL REVIEWS

Cobalt-Catalyzed C–H Activation

(2015) Marc Moselage et al.   ACS Catalysis

One-Pot Synthesis of 3-Iminoisoindolinones by a Rhodium(III)-Catalyzed and Methanol-Assisted C−H Cyanation-Cyclization Cascade withN-Alkoxyl Transfer

(2015) Jinlong Jia et al.   Asian Journal of Organic Chemistry

Low-Valent Cobalt Catalysis: New Opportunities for C–H Functionalization

(2014) Ke Gao et al.   ACCOUNTS OF CHEMICAL RESEARCH

Cobalt-Catalyzed, Aminoquinoline-Directed C(sp2)H Bond Alkenylation by Alkynes

(2014) Liene Grigorjeva et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Analysis of the Structural Diversity, Substitution Patterns, and Frequency of Nitrogen Heterocycles among U.S. FDA Approved Pharmaceuticals

(2014) Edon Vitaku et al.   JOURNAL OF MEDICINAL CHEMISTRY

Cobalt-Catalyzed C–H Arylations, Benzylations, and Alkylations with Organic Electrophiles and Beyond

(2014) Lutz Ackermann   JOURNAL OF ORGANIC CHEMISTRY

Pyrroloindolone Synthesis via a Cp*CoIII-Catalyzed Redox-Neutral Directed C–H Alkenylation/Annulation Sequence

(2014) Hideya Ikemoto et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cobalt(III)-Catalyzed Synthesis of Indazoles and Furans by C–H Bond Functionalization/Addition/Cyclization Cascades

(2014) Joshua R. Hummel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Co(III)-Catalyzed C–H Activation/Formal SN-Type Reactions: Selective and Efficient Cyanation, Halogenation, and Allylation

(2014) Da-Gang Yu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Overcoming the limitations of directed C–H functionalizations of heterocycles

(2014) Yue-Jin Liu et al.   NATURE

Cobalt-Catalyzed Direct Carbonylation of Aminoquinoline Benzamides

(2014) Liene Grigorjeva et al.   ORGANIC LETTERS

Co(acac)2/O2-Mediated Oxidative Isocyanide Insertion with 2-Aryl Anilines: Efficient Synthesis of 6-Amino Phenanthridine Derivatives

(2014) Tong-Hao Zhu et al.   ORGANIC LETTERS

Non-directed allylic C–H acetoxylation in the presence of Lewis basic heterocycles

(2014) Hasnain A. Malik et al.   Chemical Science

A Cationic High-Valent Cp*CoIIIComplex for the Catalytic Generation of Nucleophilic Organometallic Species: Directed CH Bond Activation

(2013) Tatsuhiko Yoshino et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Functionalization of C(sp2)H and C(sp3)H Bonds by Using Bidentate Directing Groups

(2013) Guy Rouquet et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cp*CoIII-Catalyzed C2-Selective Addition of Indoles to Imines

(2013) Tatsuhiko Yoshino et al.   CHEMISTRY-A EUROPEAN JOURNAL

Sustainable Practices in Medicinal Chemistry: Current State and Future Directions

(2013) Marian C. Bryan et al.   JOURNAL OF MEDICINAL CHEMISTRY

C–H bond activation enables the rapid construction and late-stage diversification of functional molecules

(2013) Joanna Wencel-Delord et al.   Nature Chemistry

Lead-Oriented Synthesis: A New Opportunity for Synthetic Chemistry

(2012) Alan Nadin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ruthenium(II)-Catalyzed C–H Bond Activation and Functionalization

(2012) Percia Beatrice Arockiam et al.   CHEMICAL REVIEWS

Palladium-Catalyzed Synthesis of Isocoumarins and Phthalides via tert-Butyl Isocyanide Insertion

(2012) Xiang-Dong Fei et al.   JOURNAL OF ORGANIC CHEMISTRY

Weak Coordination as a Powerful Means for Developing Broadly Useful C–H Functionalization Reactions

(2011) Keary M. Engle et al.   ACCOUNTS OF CHEMICAL RESEARCH

Carboxylate-Assisted Transition-Metal-Catalyzed C−H Bond Functionalizations: Mechanism and Scope

(2011) Lutz Ackermann   CHEMICAL REVIEWS

Rhodium-Catalyzed Annulation of N-Benzoylsulfonamide with Isocyanide through CH Activation

(2011) Chen Zhu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Palladium-Catalyzed Intramolecular C(sp2)–H Amidination by Isonitrile Insertion Provides Direct Access to 4-Aminoquinazolines fromN-Arylamidines

(2011) Yong Wang et al.   ORGANIC LETTERS

Palladium-Catalyzed Ligand-Directed C−H Functionalization Reactions

(2010) Thomas W. Lyons et al.   CHEMICAL REVIEWS

Auxiliary-Assisted Palladium-Catalyzed Arylation and Alkylation of sp2and sp3Carbon−Hydrogen Bonds

(2010) Dmitry Shabashov et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium- and Copper-Catalyzed Arylation of Carbon−Hydrogen Bonds

(2009) Olafs Daugulis et al.   ACCOUNTS OF CHEMICAL RESEARCH

Rhodium-Catalyzed C−C Bond Formation via Heteroatom-Directed C−H Bond Activation

(2009) Denise A. Colby et al.   CHEMICAL REVIEWS