A protein structure-guided covalent scaffold selectively targets the B1 and B2 subclass metallo-β-lactamases

Discovery of a novel covalent non-β-lactam inhibitor of the metallo-β-lactamase NDM-1

(2016) Tony Christopeit et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Structural basis of metallo-β-lactamase, serine-β-lactamase and penicillin-binding protein inhibition by cyclic boronates

(2016) Jürgen Brem et al.   Nature Communications

Combating multidrug-resistant Gram-negative bacteria with structurally nanoengineered antimicrobial peptide polymers

(2016) Shu J. Lam et al.   Nature Microbiology

Development of a Flow Cytometry-Based Method for Rapid Detection of Escherichia coli and Shigella Spp. Using an Oligonucleotide Probe

(2016) Yong Xue et al.   PLoS One

Ebselen as a potent covalent inhibitor of New Delhi metallo-β-lactamase (NDM-1)

(2015) Jiachi Chiou et al.   CHEMICAL COMMUNICATIONS

Activation free energy of Zn(II), Co(II) binding to metallo-β-lactamase ImiS

(2014) Xia Yang et al.   CHINESE CHEMICAL LETTERS

Proliferation and significance of clinically relevant β-lactamases

(2013) Karen Bush   Annals of the New York Academy of Sciences

Thermokinetic evaluation of pyrrolidinedicarboxylic acid inhibiting cefalexin hydrolysis with metallo-β-lactamase L1 from Stenotrophomonas maltophilia

(2013) Ying Shi et al.   THERMOCHIMICA ACTA

Crystal structure of NDM-1 reveals a common β-lactam hydrolysis mechanism

(2011) HongMin Zhang et al.   FASEB JOURNAL

Crystal Structure of Serratia fonticola Sfh-I: Activation of the Nucleophile in Mono-Zinc Metallo-β-Lactamases

(2011) Fátima Fonseca et al.   JOURNAL OF MOLECULAR BIOLOGY

Metallo-β-lactamases: a last frontier for β-lactams?

(2011) Giuseppe Cornaglia et al.   LANCET INFECTIOUS DISEASES

Three Decades of  -Lactamase Inhibitors

(2010) S. M. Drawz et al.   CLINICAL MICROBIOLOGY REVIEWS

Emerging carbapenemases: a global perspective

(2010) Timothy R. Walsh   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Updated Functional Classification of  -Lactamases

(2009) K. Bush et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

E. coli Transports Aggregated Proteins to the Poles by a Specific and Energy-Dependent Process

(2009) Assaf Rokney et al.   JOURNAL OF MOLECULAR BIOLOGY

Covalent Protein Labeling Based on Noncatalytic β-Lactamase and a Designed FRET Substrate

(2009) Shin Mizukami et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY