Cucurbitacin-B attenuates CCl4 -induced hepatic fibrosis in mice through inhibition of STAT-3

Protective Effects of Cucurbitacin B on Acute Lung Injury Induced by Sepsis in Rats

(2017) Shu Hua et al.   MEDICAL SCIENCE MONITOR

Anticancer effect of cucurbitacin B on MKN-45 cells via inhibition of the JAK2/STAT3 signaling pathway

(2016) You-Li Xie et al.   Experimental and Therapeutic Medicine

Characterization of the MMP/TIMP Imbalance and Collagen Production Induced by IL-1β or TNF-α Release from Human Hepatic Stellate Cells

(2016) Sacha Robert et al.   PLoS One

Novel insights into the function and dynamics of extracellular matrix in liver fibrosis

(2015) Morten A. Karsdal et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Cucurbitacin B Alters the Expression of Tumor-Related Genes by Epigenetic Modifications in NSCLC and Inhibits NNK-Induced Lung Tumorigenesis

(2015) S. Shukla et al.   Cancer Prevention Research

Cucurbitacin B inhibits immunomodulatory function and the inflammatory response in macrophages

(2015) Minju Kim et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Hepatoprotective and proapoptotic effect of Ecballium elaterium on CCl4-induced hepatotoxicity in rats

(2015) El Moataz Bellah El Naggar et al.   Asian Pacific Journal of Tropical Medicine

In Vitro and In Vivo Antitumor Activity of a Novel Semisynthetic Derivative of Cucurbitacin B

(2015) Izabella T. Silva et al.   PLoS One

Stat3 signaling activation crosslinking of TGF-β1 in hepatic stellate cell exacerbates liver injury and fibrosis

(2014) Ming-Yi Xu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Cucurbitacin B inhibits proliferation and induces apoptosis via STAT3 pathway inhibition in A549 lung cancer cells

(2014) MENG ZHANG et al.   Molecular Medicine Reports

Origin of myofibroblasts in the fibrotic liver in mice

(2014) K. Iwaisako et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cucurbitacin B potently suppresses non-small-cell lung cancer growth: Identification of intracellular thiols as critical targets

(2013) Hina Kausar et al.   CANCER LETTERS

Cucurbitacin B inhibits the translational expression of hypoxia-inducible factor-1α

(2013) Juan Ma et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

STAT3-mediated attenuation of CCl4-induced mouse liver fibrosis by the protein kinase inhibitor sorafenib

(2013) Yan-Ru Deng et al.   JOURNAL OF AUTOIMMUNITY

Fate tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its aetiology

(2013) Ingmar Mederacke et al.   Nature Communications

Red ginseng extract protects against carbon tetrachloride-induced liver fibrosis

(2013) Sung Hwan Ki et al.   Journal of Ginseng Research

Biological activities and potential molecular targets of cucurbitacins

(2012) Xiuping Chen et al.   ANTI-CANCER DRUGS

Synthesis and cytotoxic activity evaluation of dihydrocucurbitacin B and cucurbitacin B derivatives

(2012) Karen Luise Lang et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Hepatoprotective and antioxidant activity of standardized herbal extracts

(2012) ChinampudurVelusami Chandrasekaran et al.   Pharmacognosy Magazine

Update on hepatic stellate cells: pathogenic role in liver fibrosis and novel isolation techniques

(2011) Frank Tacke et al.   Expert Review of Gastroenterology & Hepatology

Prevalence of liver fibrosis and risk factors in a general population using non-invasive biomarkers (FibroTest)

(2010) Thierry Poynard et al.   BMC GASTROENTEROLOGY

La transplantation hépatique

(2009) C. Duvoux et al.   GASTROENTEROLOGIE CLINIQUE ET BIOLOGIQUE

Mechanisms of Hepatic Fibrogenesis

(2008) Scott L. Friedman   GASTROENTEROLOGY