Article
Chemistry, Inorganic & Nuclear
Lu Dong, Linke Yu, Xueli Sun, Xiongkai Tang, Xuexin You, Jiaqi Tang, Zi-Ang Nan, Dongxu Cao, Yanyuan Jia, Simin Li, Fengyu Li, Shuo Guo, Hui Shen
Summary: We report a stable gold-copper alloy nanocluster with high catalytic performance. The nanocluster exhibits high thermal stability and contains rich uncoordinated copper sites, which contribute to its extremely high catalytic activity in C-O coupling reactions. This finding is of great significance for understanding the underlying rationale of ligand-functionalized metal nanocatalysts.
INORGANIC CHEMISTRY FRONTIERS
(2023)
Article
Chemistry, Organic
Lina Cai, Qihong Lai, Lele Zhang, Guotao Xue, Yirui Zhang, Na He, Mingqiang Huang, Shirong Hu, Shunyou Cai
Summary: This study presents an efficient and practical lanthanum-catalyzed reaction method for continuous epoxy-ring opening and oxidative dehydrogenative lactonization under visible-light irradiation. The lanthanum catalyst acts as both a Lewis acid and a photocatalyst in this reaction, eliminating the need for additional photocatalysts. The method allows for convenient preparation of isochromanones with oxygen-containing spirocyclic structural units.
Article
Chemistry, Organic
Ioannis Zachilas, Marios Kidonakis, Maria Ioanna Karapanou, Manolis Stratakis
Summary: This study found that the reaction between hydrosilanes and aryl substituted cyclopropyl aldehydes or ketones catalyzed by Au nanoparticles can have two distinct ring opening reaction motifs depending on the substituents.
JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Chemistry, Organic
Swagata Baruah, Sabera Sultana, Pratiksha Bhorali, Pallabi Saikia, Sanjib Gogoi
Summary: A novel Ru(ii)-catalyzed decarbonylative annulation and direct C-H functionalization reaction of phthalic anhydrides with acrylates is reported, providing an efficient route for the synthesis of 3,7-disubstituted phthalides.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2021)
Article
Chemistry, Inorganic & Nuclear
Qingheng Lai, Oleg Ozerov
Summary: The catalytic dehydrogenative diboration (DHDB) of alkyne with HBpin was successfully achieved using Ir precursors under CO atmosphere, with higher selectivity in less polar solvents and higher CO pressure. the addition of a catalytic amount of tBuNC further improved the selectivity, leading to isolation of some DHDB products on the preparative scale.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2021)
Article
Chemistry, Organic
Amit Dahiya, Franziska Schoenebeck
Summary: A direct C(sp)-H germylation of terminal alkynes with triethyl germanium hydride was achieved. The method is simple and utilizes B(C6F5)3 catalyst combined with 2,6-lutidine as an organic base. Exclusive selectivity for dehydrogenative germylation of the alkyne over the competing hydrogermylation was observed.
Article
Chemistry, Organic
Huaxin Zhang, Yongge Xiong, Jiang Bai, Ruchun Yang, Xian-Rong Song, Qiang Xiao
Summary: We introduce a highly efficient and practical method for synthesizing gem-dibromo 1,3-oxazines through 6-endo-dig cyclization of propargylic amides, using N-bromosuccinimide (NBS) as an electrophilic source. This metal-free reaction can be carried out under mild conditions, showing good compatibility with various functional groups and providing excellent yields of the desired products. Mechanistic studies indicate that the reaction proceeds through a double electrophilic attack of NBS on the propargylic amide substrate.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Moena Kato, Koushik Ghosh, Yuji Nishii, Masahiro Miura
Summary: The study reports a rhodium-catalysed direct formylmethylation using vinylene carbonate as an ethynol equivalent. The developed catalytic system is further applied in the oxidant-free production of esters with hydrogen gas liberation. Control experiments are conducted to elucidate the reaction mechanism.
CHEMICAL COMMUNICATIONS
(2021)
Article
Chemistry, Multidisciplinary
Hiroki Tashiro, Masahiro Terada, Itaru Nakamura
Summary: Gold-catalyzed reactions were used to synthesize 2H-azirines with sulfenyl and acyl groups at the 3-position, yielding good to excellent results. These reactions involved internal transfer of sulfinyl oxygen atom and carbene insertion into the N-S bond for ring construction.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Multidisciplinary
Wen-Qiang Wu, Yunzhi Lin, Yuntong Li, Hang Shi
Summary: Given the wide availability and low cost of alkylbenzenes, direct C-H functionalization of these aromatic hydrocarbons to afford structurally complex building blocks has long been of interest in organic synthesis. Here, we describe a method for rhodium-catalyzed dehydrogenative (3 + 2) cycloaddition reactions of alkylbenzenes with 1,1-bis(phenylsulfonyl)ethylene. The generality of this catalytic method was demonstrated by carrying out reactions of a large array of alkylbenzenes to generate dihydroindene derivatives bearing two synthetically versatile sulfonyl groups.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Multidisciplinary Sciences
Teng Jia, Yi-Xin Li, Xiao-Hong Ma, Miao-Miao Zhang, Xi-Yan Dong, Jie Ai, Shuang-Quan Zang
Summary: Three-component dehydrogenative coupling reactions are important and practical methods for creating new C-N and C-C bonds, but achieving all-in-one dehydrogenative coupling functionalization through a single catalytic system remains a major challenge. In this study, a rigid-flexible-coupled copper cluster with a tridentate N-heterocyclic carbene ligand is developed to achieve dehydrogenative coupling using a single catalyst system.
NATURE COMMUNICATIONS
(2023)
Article
Chemistry, Organic
Rakesh K. Saunthwal, Kapil Mohan Saini, Nicolas Grimblat, Abhinandan K. Danodia, Sushil Kumar, Vincent Gandon, Akhilesh K. Verma
Summary: We describe an unconventional approach for the synthesis of highly decorated polyaromatic biaryls with excellent regioselectivity through site-selective Ag-catalyzed twofold electrophilic cycloisomerization followed by Au-catalyzed double C-H activation. DFT computations reveal that this reaction represents a rare example of C1-C5 endo-exo and C1-C6 endo-endo cycloaromatization, with the formation of the 6-membered ring predicted to be the result of an uncommon SEAr on a vinyl carbocation.
Article
Chemistry, Physical
Lin-Jun Qi, Chong-Yang Shi, Peng-Fei Chen, Long Li, Gang Fang, Peng-Cheng Qian, Chao Deng, Jin-Mei Zhou, Long-Wu Ye
Summary: The study presents a novel gold-catalyzed 1,1-carboalkoxylation method for the synthesis of valuable cyclic compounds, enabling asymmetric synthesis through a chirality-transfer strategy. Further mechanistic insight into the distinct migration into gold carbenes is supported by theoretical calculations.
Article
Chemistry, Organic
Bo-Han Zhu, Cang-Hai Shen, Min-Ling Nie, Fumin Zheng, Chengzhe Huang, Fan Chen, Long Li, Chao Deng, Long-Wu Ye, Peng-Cheng Qian
Summary: In this study, a novel non-noble-metal-catalyzed oxidation/cyclization reaction has been developed to synthesize diversely functionalized lactams in moderate to good yields with excellent diastereoselectivities, without the production of typical cyclopropanation products. Furthermore, the combination with another chemical reaction allows for the high diastereo- and enantioselective synthesis of chiral gamma-lactams containing three contiguous stereocenters. Density functional theory calculations suggest that this reaction possibly involves a carbon cation or proton transfer process.
Article
Chemistry, Multidisciplinary
Fabio Bellina, Matteo Biagetti, Sara Guariento, Marco Lessi, Mattia Fausti, Paolo Ronchi, Elisabetta Rosadoni
Summary: A variety of 2-alkynyl(benzo)imidazoles have been synthesized by dehydrogenative alkynylation of (benzo)imidazoles with terminal alkyne in NMP under air in the presence of Ag2CO3 as the oxidant and Pd(OAc)(2) as the catalyst precursor. The data obtained in this study support a reaction mechanism involving a non-concerted metalation deprotonation (n-CMD) pathway.
Article
Chemistry, Multidisciplinary
Marios Kidonakis, Vasiliki Kotzabasaki, Eleni Vasilikogiannaki, Manolis Stratakis
CHEMISTRY-A EUROPEAN JOURNAL
(2019)
Article
Chemistry, Multidisciplinary
Spiros A. Pergantis, Iakovos Saridakis, Alexandros Lyratzakis, Leonidas Mavroudakis, Tamsyn Montagnon
JOURNAL OF CHEMICAL EDUCATION
(2019)
Article
Chemistry, Organic
Leandros Zorba, Marios Kidonakis, Iakovos Saridakis, Manolis Stratakis
Article
Chemistry, Organic
Vasiliki Kotzabasaki, Marios Kidonak, Eleni Vassilikogiannaki, Manolis Stratakis
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
(2019)
Article
Chemistry, Applied
Michael Fragkiadakis, Marios Kidonakis, Leandros Zorba, Manolis Stratakis
ADVANCED SYNTHESIS & CATALYSIS
(2020)
Article
Chemistry, Multidisciplinary
Christian Knittl-Frank, Iakovos Saridakis, Thomas Stephens, Rafael Gomes, James Neuhaus, Antonio Misale, Rik Oost, Alberto Oppedisano, Nuno Maulide
CHEMISTRY-A EUROPEAN JOURNAL
(2020)
Article
Chemistry, Organic
Anastasia Louka, Marios Kidonakis, Iakovos Saridakis, Elisavet-Maria Zantioti-Chatzouda, Manolis Stratakis
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
(2020)
Article
Chemistry, Organic
Argyro T. Papastavrou, Marios Kidonakis, Manolis Stratakis, Michael Orfanopoulos
JOURNAL OF ORGANIC CHEMISTRY
(2020)
Article
Chemistry, Multidisciplinary
Iakovos Saridakis, Daniel Kaiser, Nuno Maulide
ACS CENTRAL SCIENCE
(2020)
Article
Chemistry, Multidisciplinary
Marios Kidonakis, Manolis Stratakis
Summary: Supported Au nanoparticles on TiO2 are capable of catalyzing the reduction of alpha-diazocarbonyl compounds into a methylene group in methanol using NH3BH3 or NaBH4. The reaction occurs rapidly at room temperature and differs from the reaction catalyzed by Pt/CeO2, which leads to hydrazones instead. Under stoichiometric Au-catalyzed conditions, ketone-type carbonyls remain intact, in contrast to the uncatalyzed conditions where they are selectively reduced by the boron hydride reagent.
Article
Chemistry, Organic
Marios Kidonakis, Michael Fragkiadakis, Manolis Stratakis
ORGANIC & BIOMOLECULAR CHEMISTRY
(2020)
Article
Chemistry, Physical
Jason D. Williams, Yuma Otake, Guilhem Coussanes, Iakovos Saridakis, Nuno Maulide, C. Oliver Kappe
