Site-Selective Functionalization of Flagellin by Steric Self-Protection: A Strategy To Facilitate Flagellin as a Self-Adjuvanting Carrier in Conjugate Vaccine

A conserved TLR5 binding and activation hot spot on flagellin

(2017) Wan Seok Song et al.   Scientific Reports

The effect of preexisting anti-carrier immunity on subsequent responses to CRM197or Qb-VLP conjugate vaccines

(2016) Michael J. McCluskie et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Transition Metal-Free Tryptophan-Selective Bioconjugation of Proteins

(2016) Yohei Seki et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cocaine Vaccine Development: Evaluation of Carrier and Adjuvant Combinations That Activate Multiple Toll-Like Receptors

(2016) Atsushi Kimishima et al.   MOLECULAR PHARMACEUTICS

Cross Reactive Material 197 glycoconjugate vaccines contain privileged conjugation sites

(2016) Uwe Möginger et al.   Scientific Reports

Functional properties of flagellin as a stimulator of innate immunity

(2016) Yuan Lu et al.   Scientific Reports

Exploring the Effect of Conjugation Site and Chemistry on the Immunogenicity of an anti-Group B Streptococcus Glycoconjugate Vaccine Based on GBS67 Pilus Protein and Type V Polysaccharide

(2015) Alberto Nilo et al.   BIOCONJUGATE CHEMISTRY

Guiding Principles in the Design of Molecular Bioconjugates for Vaccine Applications

(2015) Haipeng Liu et al.   BIOCONJUGATE CHEMISTRY

Advances in Chemical Protein Modification

(2015) Omar Boutureira et al.   CHEMICAL REVIEWS

Flagellin as Carrier and Adjuvant in Cocaine Vaccine Development

(2015) Jonathan W. Lockner et al.   MOLECULAR PHARMACEUTICS

Salmonella flagellin is a potent carrier–adjuvant for peptide conjugate to induce peptide-specific antibody response in mice

(2015) Feng Qian et al.   VACCINE

Crystal structure of FliC flagellin from Pseudomonas aeruginosa and its implication in TLR5 binding and formation of the flagellar filament

(2014) Wan Seok Song et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Defined Conjugation of Glycans to the Lysines of CRM197Guided by their Reactivity Mapping

(2014) Stefano Crotti et al.   CHEMBIOCHEM

Accurate design of co-assembling multi-component protein nanomaterials

(2014) Neil P. King et al.   NATURE

Escherichia coli-based cell free production of flagellin and ordered flagellin display on virus-like particles

(2013) Yuan Lu et al.   BIOTECHNOLOGY AND BIOENGINEERING

Sustained Protection in Mice Immunized with Fractional Doses of Salmonella Enteritidis Core and O Polysaccharide-Flagellin Glycoconjugates

(2013) Raphael Simon et al.   PLoS One

Protein carriers of conjugate vaccines: Characteristics, development and clinical trials

(2013) Michael E Pichichero   Human Vaccines & Immunotherapeutics

Designing Enzyme-like Catalysts: A Rhodium(II) Metallopeptide Case Study

(2012) Zachary T. Ball   ACCOUNTS OF CHEMICAL RESEARCH

Site-Selective Lysine Modification of Native Proteins and Peptides via Kinetically Controlled Labeling

(2012) Xi Chen et al.   BIOCONJUGATE CHEMISTRY

Modification of N-Terminal α-Amino Groups of Peptides and Proteins Using Ketenes

(2012) Anna On-Yee Chan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Antibody-Antigen-Adjuvant Conjugates Enable Co-Delivery of Antigen and Adjuvant to Dendritic Cells in Cis but Only Have Partial Targeting Specificity

(2012) Martin Kreutz et al.   PLoS One

Structural Basis of TLR5-Flagellin Recognition and Signaling

(2012) S.-i. Yoon et al.   SCIENCE

Efficacy of a Conjugate Vaccine Containing Polymannuronic Acid and Flagellin against Experimental Pseudomonas aeruginosa Lung Infection in Mice

(2011) Victoria L. Campodónico et al.   INFECTION AND IMMUNITY

Proximity-driven metallopeptide catalysis: Remarkable side-chain scope enables modification of the Fos bZip domain

(2011) Brian V. Popp et al.   Chemical Science

Flagellin as an Adjuvant: Cellular Mechanisms and Potential

(2010) S. B. Mizel et al.   JOURNAL OF IMMUNOLOGY

Evaluation of Flagella and Flagellin of Pseudomonas aeruginosa as Vaccines

(2009) V. L. Campodonico et al.   INFECTION AND IMMUNITY

Single-Step Azide Introduction in Proteins via an Aqueous Diazo Transfer

(2008) Stijn F. M. van Dongen et al.   BIOCONJUGATE CHEMISTRY

Characterization of a Three-Component Coupling Reaction on Proteins by Isotopic Labeling and Nuclear Magnetic Resonance Spectroscopy

(2008) Jesse M. McFarland et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY