Microglial Pruning of Synapses in the Prefrontal Cortex During Adolescence

Pro-inflammatory activation of primary microglia and macrophages increases 18 kDa translocator protein expression in rodents but not humans

(2017) David R Owen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Translational evaluation of translocator protein as a marker of neuroinflammation in schizophrenia

(2017) T Notter et al.   MOLECULAR PSYCHIATRY

Local Cues Establish and Maintain Region-Specific Phenotypes of Basal Ganglia Microglia

(2017) Lindsay M. De Biase et al.   NEURON

Microglia Activation in Subjects at Risk for Psychosis: Fact or Fiction?

(2017) Patricio O'Donnell   NEUROPSYCHOPHARMACOLOGY

30 Years on: How the Neurodevelopmental Hypothesis of Schizophrenia Morphed Into the Developmental Risk Factor Model of Psychosis

(2017) Robin M Murray et al.   SCHIZOPHRENIA BULLETIN

PET imaging of putative microglial activation in individuals at ultra-high risk for psychosis, recently diagnosed and chronically ill with schizophrenia

(2017) M A Di Biase et al.   Translational Psychiatry

Microglial Activity in People at Ultra High Risk of Psychosis and in Schizophrenia: An [11C]PBR28 PET Brain Imaging Study

(2016) Peter S. Bloomfield et al.   AMERICAN JOURNAL OF PSYCHIATRY

Differential expression of cytoskeletal regulatory factors in the adolescent prefrontal cortex: Implications for cortical development

(2016) Lauren P. Shapiro et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Schizophrenia risk from complex variation of complement component 4

(2016) Aswin Sekar et al.   NATURE

Synaptic number changes in the medial prefrontal cortex across adolescence in male and female rats: A role for pubertal onset

(2016) Carly M. Drzewiecki et al.   SYNAPSE

In vivo markers of inflammatory response in recent-onset schizophrenia: a combined study using [11C]DPA-713 PET and analysis of CSF and plasma

(2016) J M Coughlin et al.   Translational Psychiatry

Dendritic spine alterations in schizophrenia

(2015) Caitlin E. Moyer et al.   NEUROSCIENCE LETTERS

Brain Structure in Neuropsychologically Defined Subgroups of Schizophrenia and Psychotic Bipolar Disorder

(2015) Neil D. Woodward et al.   SCHIZOPHRENIA BULLETIN

Astrocytes Control Synapse Formation, Function, and Elimination

(2015) Won-Suk Chung et al.   Cold Spring Harbor Perspectives in Biology

Evidence for morphological alterations in prefrontal white matter glia in schizophrenia and bipolar disorder

(2014) Christa Hercher et al.   JOURNAL OF PSYCHIATRY & NEUROSCIENCE

Biological insights from 108 schizophrenia-associated genetic loci

(2014)   NATURE

Loss of mTOR-Dependent Macroautophagy Causes Autistic-like Synaptic Pruning Deficits

(2014) Guomei Tang et al.   NEURON

Morphological and Physiological Characterization of Pyramidal Neuron Subtypes in Rat Medial Prefrontal Cortex

(2013) Karlijn I. van Aerde et al.   CEREBRAL CORTEX

Abnormal expression of glutamate transporters in temporal lobe areas in elderly patients with schizophrenia

(2013) Dan Shan et al.   SCHIZOPHRENIA RESEARCH

Dendritic remodeling in the adolescent medial prefrontal cortex and the basolateral amygdala of male and female rats

(2013) Wendy A. Koss et al.   SYNAPSE

Clearing the Dead: Apoptotic Cell Sensing, Recognition, Engulfment, and Digestion

(2013) A. Hochreiter-Hufford et al.   Cold Spring Harbor Perspectives in Biology

The Complement System: An Unexpected Role in Synaptic Pruning During Development and Disease

(2012) Alexander H. Stephan et al.   Annual Review of Neuroscience

Periadolescent maturation of the prefrontal cortex is sex-specific and is disrupted by prenatal stress

(2012) Julie A. Markham et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Reactive Astrocytes Overexpress TSPO and Are Detected by TSPO Positron Emission Tomography Imaging

(2012) S. Lavisse et al.   JOURNAL OF NEUROSCIENCE

Arg Kinase Regulates Prefrontal Dendritic Spine Refinement and Cocaine-Induced Plasticity

(2012) S. L. Gourley et al.   JOURNAL OF NEUROSCIENCE

Increased inflammatory markers identified in the dorsolateral prefrontal cortex of individuals with schizophrenia

(2012) S G Fillman et al.   MOLECULAR PSYCHIATRY

Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner

(2012) Dorothy P. Schafer et al.   NEURON

Dendritic spine pathology in schizophrenia

(2012) J.R. Glausier et al.   NEUROSCIENCE

Ultrastructure of Synapses in the Mammalian Brain

(2012) K. M. Harris et al.   Cold Spring Harbor Perspectives in Biology

Loss of PSD-95 Enrichment Is Not a Prerequisite for Spine Retraction

(2011) G. F. Woods et al.   JOURNAL OF NEUROSCIENCE

Dendritic spine pathology in neuropsychiatric disorders

(2011) Peter Penzes et al.   NATURE NEUROSCIENCE

Extraordinary neoteny of synaptic spines in the human prefrontal cortex

(2011) Zdravko Petanjek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuroanatomical Maps of Psychosis Onset: Voxel-wise Meta-Analysis of Antipsychotic-Naive VBM Studies

(2011) P. Fusar-Poli et al.   SCHIZOPHRENIA BULLETIN

Synaptic Pruning by Microglia Is Necessary for Normal Brain Development

(2011) R. C. Paolicelli et al.   SCIENCE

Microglia Shape Adult Hippocampal Neurogenesis through Apoptosis-Coupled Phagocytosis

(2010) Amanda Sierra et al.   Cell Stem Cell

Peripheral benzodiazepine receptors in patients with chronic schizophrenia: a PET study with [11C]DAA1106

(2010) Akihiro Takano et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

When cortical development goes wrong: schizophrenia as a neurodevelopmental disease of microcircuits

(2010) Laurence Garey   JOURNAL OF ANATOMY

Microglial Interactions with Synapses Are Modulated by Visual Experience

(2010) Marie-Ève Tremblay et al.   PLOS BIOLOGY

Microglial Physiology: Unique Stimuli, Specialized Responses

(2009) Richard M. Ransohoff et al.   Annual Review of Immunology

Glutamatergic deficits and parvalbumin-containing inhibitory neurons in the prefrontal cortex in schizophrenia

(2009) BKY Bitanihirwe et al.   BMC Psychiatry

Resting Microglia Directly Monitor the Functional State of Synapses In Vivo and Determine the Fate of Ischemic Terminals

(2009) H. Wake et al.   JOURNAL OF NEUROSCIENCE

Neuroinflammation in Schizophrenia-Related Psychosis: A PET Study

(2009) J. Doorduin et al.   JOURNAL OF NUCLEAR MEDICINE

Rapid formation and selective stabilization of synapses for enduring motor memories

(2009) Tonghui Xu et al.   NATURE

Experience-dependent structural synaptic plasticity in the mammalian brain

(2009) Anthony Holtmaat et al.   NATURE REVIEWS NEUROSCIENCE

Normal Development of Brain Circuits

(2009) Gregory Z Tau et al.   NEUROPSYCHOPHARMACOLOGY

Translocator protein (TSPO 18kDa) is expressed by neural stem and neuronal precursor cells

(2009) Balázs Varga et al.   NEUROSCIENCE LETTERS

Gray Matter in First-Episode Schizophrenia Before and After Antipsychotic Drug Treatment. Anatomical Likelihood Estimation Meta-analyses With Sample Size Weighting

(2009) M. Leung et al.   SCHIZOPHRENIA BULLETIN

Altered Vesicular Glutamate Transporter Expression in the Anterior Cingulate Cortex in Schizophrenia

(2008) Akin Oni-Orisan et al.   BIOLOGICAL PSYCHIATRY

Microglia Activation in Recent-Onset Schizophrenia: A Quantitative (R)-[11C]PK11195 Positron Emission Tomography Study

(2008) Bart N. van Berckel et al.   BIOLOGICAL PSYCHIATRY

Expression of the translocator protein of 18 kDa by microglia, macrophages and astrocytes based on immunohistochemical localization in abnormal human brain

(2008) M. Cosenza-Nashat et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Reductions in frontal, temporal and parietal volume associated with the onset of psychosis

(2008) S BORGWARDT et al.   SCHIZOPHRENIA RESEARCH

Immunological aspects in the neurobiology of suicide: Elevated microglial density in schizophrenia and depression is associated with suicide

(2006) Johann Steiner et al.   JOURNAL OF PSYCHIATRIC RESEARCH