Rapamycin improves insulin resistance and hepatic steatosis in type 2 diabetes rats through activation of autophagy

Robust Anticancer Efficacy of a Biologically Synthesized Tumor Acidity-Responsive and Autophagy-Inducing Functional Beclin 1

(2018) Guo-Bin Ding et al.   ACS Applied Materials & Interfaces

Sestrin 2 induces autophagy and attenuates insulin resistance by regulating AMPK signaling in C2C12 myotubes

(2017) Huige Li et al.   EXPERIMENTAL CELL RESEARCH

Adiponectin deficiency rescues high-fat diet-induced hepatic injury, apoptosis and autophagy loss despite persistent steatosis

(2017) R Guo et al.   INTERNATIONAL JOURNAL OF OBESITY

Pectic Bee Pollen Polysaccharide from Rosa rugosa Alleviates Diet-Induced Hepatic Steatosis and Insulin Resistance via Induction of AMPK/mTOR-Mediated Autophagy

(2017) Xinzhi Li et al.   MOLECULES

Global aetiology and epidemiology of type 2 diabetes mellitus and its complications

(2017) Yan Zheng et al.   Nature Reviews Endocrinology

Metformin attenuates hepatic insulin resistance in type-2 diabetic rats through PI3K/Akt/GLUT-4 signalling independent to bicuculline-sensitive GABAA receptor stimulation

(2017) Debapriya Garabadu et al.   PHARMACEUTICAL BIOLOGY

Caffeic Acid Attenuates Diabetic Kidney Disease via Modulation of Autophagy in a High-Fat Diet/Streptozotocin- Induced Diabetic Rat

(2017) Marwa Matboli et al.   Scientific Reports

Azuki bean (Vigna angularis) extract reduces oxidative stress and stimulates autophagy in the kidneys of streptozotocin-induced early diabetic rats

(2016) Shin Sato et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Novel synergic antidiabetic effects of Astragalus polysaccharides combined with Crataegus flavonoids via improvement of islet function and liver metabolism

(2016) KAI CUI et al.   Molecular Medicine Reports

Insulin Resistance in Relation to Lipids and Inflammation in Type-2 Diabetic Patients and Non-Diabetic People

(2016) Ying-Mei Feng et al.   PLoS One

Prognostic value of the autophagy markers LC3 and p62/SQSTM1 in early-stage non-small cell lung cancer

(2016) Anna M. Schläfli et al.   Oncotarget

Autophagy in Diabetes: β-Cell Dysfunction, Insulin Resistance, and Complications

(2015) Adam D. Barlow et al.   DNA AND CELL BIOLOGY

Fasting and OGTT-derived Measures of Insulin Resistance as Compared With the Euglycemic-Hyperinsulinemic Clamp in Nondiabetic Finnish Offspring of Type 2 Diabetic Individuals

(2015) Carlos Lorenzo et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Autophagy regulates insulin resistance following endoplasmic reticulum stress in diabetes

(2015) Ning Zhang et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Dihydromyricetin improves skeletal muscle insulin resistance by inducing autophagy via the AMPK signaling pathway

(2015) Linying Shi et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

PGRN Induces Impaired Insulin Sensitivity and Defective Autophagy in Hepatic Insulin Resistance

(2015) Jiali Liu et al.   MOLECULAR ENDOCRINOLOGY

Sodium Salicylate Reduced Insulin Resistance in the Retina of a Type 2 Diabetic Rat Model

(2015) Youde Jiang et al.   PLoS One

Paradoxical effect of rapamycin on inflammatory stress-induced insulin resistance in vitro and in vivo

(2015) Ping Yang et al.   Scientific Reports

Pollen Typhaetotal flavone improves insulin resistance in high-fat diet and low-dose streptozotocin-induced type 2 diabetic rats

(2014) Xiao-Tao Feng et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Gallic acid attenuates high-fat diet fed-streptozotocin-induced insulin resistance via partial agonism of PPARγ in experimental type 2 diabetic rats and enhances glucose uptake through translocation and activation of GLUT4 in PI3K/p-Akt signaling pathway

(2014) Gopalsamy Rajiv Gandhi et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Green Tea, Black Tea, and Oolong Tea Polyphenols Reduce Visceral Fat and Inflammation in Mice Fed High-Fat, High-Sucrose Obesogenic Diets

(2014) David Heber et al.   JOURNAL OF NUTRITION

Fresh pomegranate juice ameliorates insulin resistance, enhances β-cell function, and decreases fasting serum glucose in type 2 diabetic patients

(2014) S.A. Banihani et al.   NUTRITION RESEARCH

Beneficial Metabolic Effects of Rapamycin Are Associated with Enhanced Regulatory Cells in Diet-Induced Obese Mice

(2014) Kassem Makki et al.   PLoS One

Impaired Autophagy Contributes to Adverse Cardiac Remodeling in Acute Myocardial Infarction

(2014) Xiaoqian Wu et al.   PLoS One

The prognostic value of autophagy-related markers beclin-1 and microtubule-associated protein light chain 3B in cancers: a systematic review and meta-analysis

(2014) Yuyu He et al.   TUMOR BIOLOGY

Evaluation of Hypoglycemic Efficacy of Tangningtongluo Formula, a Traditional Chinese Miao Medicine, in Two Rodent Animal Models

(2014) Long Cheng et al.   Journal of Diabetes Research

Adiponectin knockout accentuates high fat diet-induced obesity and cardiac dysfunction: Role of autophagy

(2013) Rui Guo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Autophagy activation by rapamycin improves left ventricular function in diabetic rats

(2013) Xiang Zhou et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Clinical Utility of LC3 and p62 Immunohistochemistry in Diagnosis of Drug-Induced Autophagic Vacuolar Myopathies: A Case-Control Study

(2012) Han S. Lee et al.   PLoS One

Autophagy: A Potential Link between Obesity and Insulin Resistance

(2010) Patrice Codogno et al.   Cell Metabolism

Chronic Rapamycin Treatment Causes Glucose Intolerance and Hyperlipidemia by Upregulating Hepatic Gluconeogenesis and Impairing Lipid Deposition in Adipose Tissue

(2010) V. P. Houde et al.   DIABETES

Hepatic Autophagy Is Suppressed in the Presence of Insulin Resistance and Hyperinsulinemia

(2009) Hui-Yu Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy Is Important in Islet Homeostasis and Compensatory Increase of Beta Cell Mass in Response to High-Fat Diet

(2008) Chie Ebato et al.   Cell Metabolism

Rapamycin inhibits osteoblast proliferation and differentiation in MC3T3-E1 cells and primary mouse bone marrow stromal cells

(2007) Ujjal K. Singha et al.   JOURNAL OF CELLULAR BIOCHEMISTRY