Article
Biochemistry & Molecular Biology
Yan Li, Ziqian Liu, Xin Wan, Lingying Xie, Hui Chen, Guo Qu, Han Zhang, Yue-Fei Zhang, Shicheng Zhao
Summary: In this study, xanthan gum-based composites were successfully graft-modified by amantadine (XG-Fe3+/AM) to enhance the adsorption capacity and selectivity for methylene blue (MB) from aqueous solutions. The adsorption equilibrium of MB was achieved within 5 minutes at an initial concentration of 100 mg/L, with a maximum adsorption capacity of 565 mg/g. XG-Fe3+/AM showed a high removal rate of 95% for MB even after 5 desorption-regeneration cycles. The adsorption performance of MB was systematically examined by pH, contact time, temperature, and initial dye concentration.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Engineering, Environmental
Ahmed M. Shahr El-Din, Tarek Monir, Emad H. Borai
Summary: A nanocomposite material was developed for the removal of Th(IV), U(VI) and Fe(III) from rare earth chloride liquor, showing high adsorption capacity. Selective removal of target metal ions was achieved under pH 2.0 condition.
JOURNAL OF POLYMERS AND THE ENVIRONMENT
(2021)
Article
Engineering, Chemical
Tikina Rani Sethy, Trinath Biswal, Prafulla Kumar Sahoo
Summary: Recently, polymer nanocomposite hydrogel (PNC-hydrogel) has attracted attention for its cost effectiveness, high processability, modified surface area, and enhanced absorptivity in water remediation. Chitosan-based bionanocomposite hydrogel (SCB-hydrogel) has been prepared and investigated for adsorbing toxic heavy metallic ions from wastewater. The grafted biopolymer-based SCB-hydrogel showed high adsorption efficiency and reusability for lanthanide ions, making it a promising bio-adsorbent for wastewater treatment.
SEPARATION AND PURIFICATION TECHNOLOGY
(2023)
Article
Polymer Science
Mehdi Rahmani, Ahmad Dadvand Koohi
Summary: In this study, a MMT/XG-Alg hybrid hydrogel nanocomposite was synthesized for the adsorption of MG. The structure and morphology of the hybrid nanocomposites were identified using BET, FTIR and SEM analyses. The optimal adsorption conditions were determined to be pH = 6, temperature 318 K, contact time 240 min, and the maximum adsorption capacity was found to be 769.23 mg/g. The adsorption process followed the Langmuir isotherm model, with MMT(0.5CMC)/XG-Alg showing the highest adsorption capacity. Kinetics were described by the pseudo-second order model, and thermodynamic parameters indicated an endothermic and spontaneous sorption process.
Article
Environmental Sciences
Bin Ji, Wencai Zhang
Summary: This study focused on the recovery of rare earth elements (REEs) from kaolinite through selective leaching and the synthesis of zeolites from the leaching residue. The results showed that the pH static leaching method achieved over 90% leaching of REEs from metakaolinite, while only extracting less than 2% of the major constituents. Zeolites with different compositions were successfully synthesized, and high purity sodalite exhibited superior adsorption capacity for Ce3+ compared to zeolite A. These findings suggest that kaolinite could be a potential source for REE recovery, and the resulting leaching residue could be used for the synthesis of zeolites as promising adsorbents for Ce3+ recovery.
Article
Nanoscience & Nanotechnology
Alexander T. Brown, Kenneth J. Balkus
Summary: There is a need for the development of new solid-phase adsorbents for element extraction from coal ash. High surface area carbon adsorbents are effective in adsorbing rare earth elements, and MFC-O has shown exceptional extraction capabilities for rare earth elements, thorium, and uranium. The binding properties of MFC-O make it an attractive material for selective extraction of rare earth elements from coal ash.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Chemistry, Applied
Jwala Patel, Sabyasachi Maiti, N. S. Hari Narayana Moorthy
Summary: In this study, repaglinide-loaded hydrogel particles were successfully fabricated using carboxyethyl xanthan gum and carboxymethyl xanthan gum. The controlled drug delivery performance of these particles was evaluated, and it was found that acetylated hydrogel particles exhibited high drug entrapment efficiency and extended drug release, which could effectively control diabetes.
CARBOHYDRATE POLYMERS
(2022)
Review
Environmental Sciences
Muhammad Usman, Muhammad Babar Taj, Sonia Alexandra Correia Carabineiro
Summary: The importance of water for all living organisms cannot be underestimated, thus protecting its sources is crucial. Biopolymers, such as guar gum and xanthan gum, are gaining attention due to their eco-friendly, non-toxic, reusable, abundant and cost-effective properties. Gum-based nanocomposites have shown great potential in removing heavy metals and colored dyes from water through adsorption and degradation. This review provides a comprehensive analysis of the significance of gum-based nanomaterials in wastewater treatment, including preparation, characterization, kinetics, and the involved mechanisms.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Chemistry, Physical
Hemant Mittal, Ali Al Alili, Pranay P. Morajkar, Saeed M. Alhassan
Summary: This study focused on preparing xanthan gum based hydrogel nanocomposites via chemical-crosslinking with graphene oxide for the highly efficient adsorption of crystal violet dye from contaminated wastewater. The results showed that the material has the potential to treat cationic dyes contaminated wastewater in large quantities, with good reuse efficiency demonstrated through twenty continuous cycles of adsorption-desorption.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Engineering, Environmental
Hadi Abdollahi, Soudabeh Maleki, Hani Sayahi, Mahdi Gharabaghi, Mohammad Hossein Karimi Darvanjooghi, Sara Magdouli, Satinder Kaur Brar
Summary: A series of nanocomposites adsorbents with different magnetite/carbon black ratios were synthesized for separating LREEs, showing high adsorption efficiency and a maximum adsorption capacity of 370 mg/g. The adsorption behavior fits well with Langmuir isotherm and pseudo-first-order kinetic model. Using a Neural Network to predict the adsorption kinetics of LREEs showed high accuracy and validation with other research studies.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Energy & Fuels
Akinleye O. Sowunmi, Vincent E. Efeovbokhan, Oyinkepreye D. Orodu, Babalola A. Oni
Summary: The study compared the EOR performance of Gum Arabic (GA) and Xanthan Gum (XG) solutions, showing similar oil recovery for 1.0 wt% GA and 0.1 wt% XG polymeric solutions. GA exhibited Newtonian viscosity at high shear rates. The impact of nano-polymeric solutions on oil recovery was found to be higher than that of polymeric solutions.
JOURNAL OF PETROLEUM EXPLORATION AND PRODUCTION TECHNOLOGY
(2022)
Article
Engineering, Chemical
Xuyi Wei, Xiaohui Mao, Wenqing Qin, Hongbo Zeng, Junwei Han
Summary: In this study, a natural kaolinite loaded onto alginate hydrogel was used to prepare ALG@KLN composites, which achieved efficient recovery of rare earth elements (REEs) using an eco-friendly method. ALG@KLN exhibited high adsorption capacity and reusability, and the adsorption mechanism was mainly through chemical chelation and electrostatic interaction. This research is of great significance for the development of economical and eco-friendly REE adsorbents.
SEPARATION AND PURIFICATION TECHNOLOGY
(2023)
Article
Environmental Sciences
Yinzhi Lv, Lin Chen, Anning Zhang, Guodong Sheng, Qing Liao
Summary: The separation and recycling of rare earth elements (REEs) are important due to their high demand, limited resources, specific uses, and environmental issues. In this study, two-dimensional Ti3C2Tx MXene was used to remove Nd(III) and La(III) REEs from water, and its physicochemical properties were investigated. Various parameters and adsorption kinetics and isotherms were examined. The results showed that Ti3C2Tx MXene has a great potential for extracting REEs from an aqueous solution.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Engineering, Chemical
Chunhui Zhong, Huihui Wang, Liangzhu Zhang, Mengchi Guo, Bo Feng
Summary: The study revealed that xanthan gum inhibited the flotation of molybdenite and talc, but molybdenite could recover its floatability in the presence of potassium butyl xanthate. The flotation separation of molybdenite and talc was achieved by the physical adsorption of xanthan gum on molybdenite and the inhibiting effect on talc, demonstrating the potential application of xanthan gum as a depressant in mineral processing.
Article
Chemistry, Physical
Magdy Khalil, Gehan Abdel Rahman Sadek Dakroury, Emad Hassan Borai
Summary: Due to the growing demand for rare-earth elements in high-tech applications, new sustainable approaches to rare earth element recycling and separation have been developed. In this study, a novel nano composite, SA-g-(PAA/CuO), was created for the sorption and separation of rare earth elements. The results showed that the composite efficiently separates different rare earth elements based on their properties.
SURFACES AND INTERFACES
(2022)
Article
Thermodynamics
Mingming Zhang, Anton Timoshin, Essam A. Al-Ammar, Mika Sillanpaa, Guiju Zhang
Summary: The current paper proposes a new hybrid system based on a binary-geothermal system to generate power, cooling capacity, freshwater, and hydrogen. The system integrates organic Rankine cycle, ejector refrigeration cycle, proton exchange membrane electrolyzer, and reverse osmosis desalination unit. Through precise modeling in Matlab, the system's performance is optimized using multi-objective grey wolf optimization. Results show that the system can achieve high power output, cooling capacity, hydrogen production, and freshwater generation with cost-effectiveness.
Article
Materials Science, Ceramics
Andrei Ivanets, Vladimir Prozorovich, Olim Ruzimuradov, Xintai Su, Ahmad Hosseini-Bandegharaei, Zhao Wang, Varsha Srivastava, Mika Sillanpaa
Summary: A novel nanostructured Fenton-like catalyst based on La-doped MgFe2O4 was developed to enhance the degradation of carbamazepine. The physicochemical properties of the catalyst were studied, and the optimal conditions for maximum degradation efficiency were determined. The developed catalyst demonstrated high stability and efficiency, making it suitable for treating wastewaters polluted with organic active compounds.
JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY
(2023)
Review
Green & Sustainable Science & Technology
Mokgehle R. Letsoalo, Thandiwe Sithole, Steven Mufamadi, Zvanaka Mazhandu, Mika Sillanpaa, Ajeet Kaushik, Tebogo Mashifana
Summary: The presence of pharmaceutical contaminants (PCs) in the environment, including water and aquatic life, is a continuous threat to human health and the natural cycle. In particular, the accumulation of non-degradable water-soluble residues in water streams and groundwater has raised serious concerns and is now a focus of the United Nations' Sustainable Development Goals 2030. This article explores the challenges and potential solutions for the selective detection and efficient remediation of PCs in wastewater using nano-enabled functional systems.
JOURNAL OF CLEANER PRODUCTION
(2023)
Article
Environmental Sciences
Heba Saed Kariem Alawamleh, Seyedsahand Mousavi, Danial Ashoori, Hayder Mahmood Salman, Sasan Zahmatkesh, Mika Sillanpaa
Summary: The study aims to improve the performance of membrane treatment for oily wastewater. The effects of pre-treatment, membrane modification, and operational parameters on the microfiltration membrane system were investigated. The results showed that using PFS as a coagulant at pH=6 can achieve a COD reduction of 98%, while using PFC at the same conditions only removes 81% of COD.
Article
Green & Sustainable Science & Technology
Rajesh Babu Katiyar, Suresh Sundaramurthy, Anil Kumar Sharma, Suresh Arisutha, Moonis Ali Khan, Mika Sillanpaa
Summary: Urbanization and population growth lead to a substantial increase in solid waste generation. Vermicomposting, which employs earthworms to recycle solid waste, proves to be a sustainable solution. This study explores the impact of earthworm-processed solid waste manure (vermicompost) on the growth, productivity, and chemical characteristics of chili and brinjal plants in different wooden reactors. The findings reveal that polyculture reactors with vermicompost soil exhibit significantly higher yields of both chili and brinjal compared to monoculture reactors.
Article
Chemistry, Physical
Sadia Aroob, Sonia A. C. Carabineiro, Muhammad Babar Taj, Ismat Bibi, Ahmad Raheel, Tariq Javed, Rana Yahya, Walla Alelwani, Francis Verpoort, Khanita Kamwilaisak, Saleh Al-Farraj, Mika Sillanpaa
Summary: In this study, CuO nanoparticles were synthesized by a simple, one-pot mechanochemical approach using the leaf extract of Seriphidium oliverianum as a reducing and stabilizing agent. The CuO NPs showed high potential for degrading water-soluble industrial dyes, with degradation rates of 65.231% +/- 0.242 for methyl green (MG) and 65.078% +/- 0.392 for methyl orange (MO). This bio-mechanochemically synthesized CuO NPs are promising candidates for efficient dye removal from water.
Article
Chemistry, Analytical
Kanthappa Bhimaraya, Jamballi G. Manjunatha, Karnayana P. Moulya, Ammar M. Tighezza, Munirah D. Albaqami, Mika Sillanpaa
Summary: The electrochemically polymerized glycine layered carbon paste electrode (EPGNLCPE) was used as an easy and rapid analytical tool for the analysis of levofloxacin (LN). The EPGNLCPE sensor, compared to the bare carbon paste electrode (BCPE), showed improved surface features and activities. Under optimized conditions, the differential pulse voltammetry method using EPGNLCPE exhibited good linearity, low limit of detection, and low limit of quantification for the analysis of LN. Real-time application of the sensor showed good recovery of LN in medicinal samples.
Review
Engineering, Environmental
Thuhin Kumar Dey, Jingwei Hou, Mika Sillanpaa, Biplob Kumar Pramanik
Summary: Micro/nanoplastics (MPs/NPs) are widespread and pose a significant threat to the environment. Metal-organic frameworks (MOFs)-based membranes have gained attention for their potential in removing MPs/NPs from water and wastewater. However, challenges such as re-aggregation, cross-contamination, and poor structural stability need to be addressed for the successful application of MOF membranes.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Engineering, Chemical
Glaydson S. dos Reis, Julie Thivet, Ewen Laisne, Varsha Srivastava, Alejandro Grimm, Eder C. Lima, Davide Bergna, Tao Hu, Mu. Naushad, Ulla Lassi
Summary: In this study, a selenium-doped mesoporous biochar was successfully prepared and used for the adsorption of sodium diclofenac and reactive orange 16 dye. The selenium doping significantly affected the morphology and physicochemical properties of the biochar. The developed biochar exhibited high adsorption capacity for both molecules, driven by multiple mechanisms including pore filling, pi-pi interaction, and hydrogen bonding. This work provides a feasible approach for the development of selenium-doped biochar adsorbents for wastewater treatment.
CHEMICAL ENGINEERING SCIENCE
(2023)
Article
Chemistry, Physical
Abir Melliti, Murat Yilmaz, Mika Sillanpaa, Bechir Hamrouni, Radek Vurm
Summary: In this study, low-cost activated carbon (AC-DPF) made from date palm fiber waste was used to remove lead and copper from water systems. AC-DPF had a large surface area and high adsorption capacity, with removal efficiencies of 92% for Pb(II) and 80% for Cu(II). The adsorption kinetics and thermodynamics of AC-DPF were investigated, and competitive and antagonistic effects were observed in the multicomponent system. Overall, AC-DPF showed great potential as a highly promising, effective, and feasible adsorbent for heavy metal removal.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2023)
Article
Biochemistry & Molecular Biology
Imran Ali, Anastasya Gaydukova, Tatiana Kon'kova, Zeid Abdullah ALOthman, Mika Sillanpaa
Summary: This study investigated the acid leaching process of grinding waste from a heat-resistant nickel alloy. Optimal conditions for acid dissolution were established to maximize the extraction of nickel, the main component of the alloy. These results are significant for industry professionals in metal recovery and environmentalists in waste treatment.
Review
Chemistry, Multidisciplinary
Varsha Srivastava, Katja Lappalainen, Annu Rusanen, Gabriel Morales, Ulla Lassi
Summary: This review focuses on the catalytic transformation of lignocellulosic biomass into value-added chemicals using MOF-based catalyst/composite materials. The tunability of MOF-based catalysts allows for tailoring their catalytic activity and selectivity through functionalization. The production of HMF and Furfural from lignocellulosic biomass is emphasized due to their versatility as intermediates for various biobased chemicals and fuels. The effects of different experimental parameters on biomass conversion by MOF-based catalysts are also discussed.
Article
Chemistry, Physical
Atef El Jery, Moutaz Aldrdery, Ujwal Ramesh Shirode, Juan Carlos Orosco Gavilan, Abubakr Elkhaleefa, Mika Sillanpaa, Saad Sh. Sammen, Hussam H. Tizkam
Summary: The shortage of water resources has led to extensive research in the development of effective and affordable wastewater treatment methods. In this study, a modified catalyst was synthesized using wet impregnation and the hydrothermal technique. The catalyst showed excellent performance in a heterogeneous quasi-electro-Fenton reaction and remained stable under different operational conditions. The findings of this study clarify the potential of the heterogeneous zeolite catalyst in wastewater treatment.
Article
Engineering, Environmental
Edris Rezaei, Behrouz Jafari, Mohsen Abbasi, Seyed Abdollatif Hashemifard, Shahriar Osfouri, Mahmoud Ramazani, Nadir Dizge, Mika Sillanpaa
Summary: The purpose of this study is to reuse greywater and prevent its release into the environment. The combined method of membrane and advanced oxidation was used to reduce the COD to the standard value. Ten types of membrane samples with different concentrations of kaolin, alumina, and calcium carbonate were prepared. The results showed that the addition of calcium carbonate increased the porosity and average pore size of the membrane.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2023)
Article
Chemistry, Physical
Mohammad K. Okla, M. Kalil Rahiman, Mostafa A. Abdel-Maksoud, Ibrahim A. Alaraidh, Abdulrahman A. Alatar, Saud S. Al-amri, Hamada AbdElgawad, Mika Sillanpaa, S. Sudheer Khan
Summary: In this study, an n-p-n nanohybrid material was designed and synthesized, which consisted of ultrathin-Bi2WO6, CoFe2O4 nanosheets, spherical MnWO4, and carbon quantum dots. The experimental results demonstrated that the nanohybrid material exhibited excellent visible light absorption and efficient Cefixime photodegradation.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2023)
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)