Article
Engineering, Chemical
Guoquan Tu, Xin Liu, Zhuo Li, Shengzhe Li, Jie Liu, Weiyi Li
Summary: This study utilized OCT to characterize the gelation process of chitosan dissolved in LiOH/urea aqueous solution, revealing the competition mechanism during gel formation. The research demonstrated that adjusting the concentration of alkali can effectively influence the porous morphology of chitosan membranes.
JOURNAL OF MEMBRANE SCIENCE
(2021)
Article
Chemistry, Multidisciplinary
Yi Zhong, Xi Zhang, Qing Zhang, Jie Cai
Summary: Chitin and chitosan have great potential applications in biomaterials, wearable flexible electronic devices, energy conversion and storage materials, and food packaging. However, further investigation is needed for the development of a universal green aqueous solvent for them and a comprehensive understanding of their dissolution mechanism. This study analyzed the rapid dissolution of chitin and chitosan with a degree of deacetylation less than 80% in the universal solvent KOH/urea aqueous solution, and proposed a desolvation-intercalation dissolution mechanism. It could guide future research on chitin and chitosan at the molecular level and facilitate the development of advanced materials based on them.
Article
Engineering, Environmental
Sudipta Chatterjee, Godfred Ohemeng-Boahen, Divine Damertey Sewu, Barnabas Asamoah Osei, Seung Han Woo
Summary: Alkali treatment increased the adsorption capacity of goethite impregnated chitosan capsules for Congo red and caused changes in their physico-chemical properties, morphology, and mechanical stability.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2022)
Article
Chemistry, Applied
Pengbo Wang, Xingshuang Lv, Bingqian Zhang, Tengbin Wang, Chenbo Wang, Jiaxi Sun, Kun Zhang, Ya'nan Wu, Jian Zhao, Yongqin Zhang
Summary: With the assistance of 13C NMR and 1H-13C HSQC, a novel 1H NMR assay has been developed for determining substitution sites and degrees in hydroxypropyl chitosan (HPCS). By optimizing sample preparation and measurement method, the method allows for accurate discrimination and determination of NH2-substitution, OH-substitution, and degree of acetylation. The analysis is extendable to other amino-containing saccharides, making it a widely applicable method in structural analysis.
CARBOHYDRATE POLYMERS
(2021)
Article
Chemistry, Inorganic & Nuclear
Miguel A. Gonzalvez, Paul Bernhardt, Merce Font-Bardia, Albert Gallen, Jesus Jover, Montserrat Ferrer, Manuel Martinez
Summary: A series of alkali-metal inclusion complexes of a molecular cube have been successfully prepared through a redox-triggered self-assembly process. These complexes are highly stable and soluble in aqueous media, and show inertness to cation exchange while the size of the portal also plays a determining role in the exchange process.
INORGANIC CHEMISTRY
(2021)
Article
Construction & Building Technology
Jian Li, Ru Wang, Yu Xu
Summary: The effects of different cellulose ethers on the setting and hydration process of calcium sulphoaluminate (CSA) cement were studied in this research. The results showed that the type and dosage of cellulose ethers had an impact on the setting time and hydration heat of the cement.
CONSTRUCTION AND BUILDING MATERIALS
(2022)
Article
Materials Science, Paper & Wood
Eugene Huh, Ji-Hyun Yang, Chang-Ha Lee, Ik-Sung Ahn, Byung Jin Mhin
Summary: The 3D-RISM-KH theory combined with KBI was used to study the role of alkali metal hydroxides in cellulose solvation. The results showed that Li+ hydrates had the closest interaction with cellulose due to their high charge density, explaining the difference in cellulose solubilities in different aqueous solutions.
Article
Biochemistry & Molecular Biology
Reza Davarnejad, Kasra Sarvmeili, Zahra Safari, John F. Kennedy
Summary: Chitosan nanoparticles, characterized by SEM, XRD, and FT-IR analyses, were used as an efficient and reusable adsorbent for removing ethinylestradiol from wastewater. The experimental conditions were optimized using Design Expert software, and the results showed that contact time, adsorbent dosage, and pH positively influenced estrogen removal while the initial concentration of estrogen had a negative effect. The optimum conditions for estrogen removal (92.50%) were found to be a contact time of 220 min, adsorbent dosage of 1.45 g/l, pH of 7.3, and initial concentration of 5.7 mg/l. Moreover, the Langmuir isotherm and pseudo-second order models were suitable for describing the estrogen adsorption process on chitosan nanoparticles.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biochemistry & Molecular Biology
Erika Saiki, Hiroki Iwase, Yoshiki Horikawa, Toshiyuki Shikata
Summary: This study investigated the structure of hydroxypropylmethyl cellulose (HpMC) samples with different molecular weights and degrees of substitution using various measurement techniques. The results showed that the HpMC samples exhibited characteristics of semiflexible rod-like molecules, which became more pronounced with increasing molecular weight.
Article
Chemistry, Applied
Zhengbo Lu, Lei Zou, Xiaoman Zhou, Di Huang, Yongjun Zhang
Summary: This study systematically investigated the effects of treatment parameters in a two-step basic route for chitosan hydrogel preparation. The thermal gelation was found to be the crucial step determining the structure and properties of the final gel.
CARBOHYDRATE POLYMERS
(2022)
Article
Chemistry, Multidisciplinary
Nikita Orekhov, Nikolay Kondratyuk, Mikhail Logunov, Alexandra Timralieva, Vladimir Shilovskikh, Ekaterina Skorb
Summary: This study provides molecular insights into the self-assembly of melamine cyanurate in aqueous solution and identifies mechanisms of aggregation. The research suggests that the formation of small M-CA complexes is mainly stabilized through aromatic p-p stacking rather than hydrogen bond formation. It also demonstrates that changing the concentration ratio of M to CA leads to a variation in the structure of critical nuclei, indicating a potential for the programmable design of functional supramolecular materials.
CRYSTAL GROWTH & DESIGN
(2021)
Article
Biochemistry & Molecular Biology
Hao Liu, Xulin Jiang
Summary: In this study, a series of sulfopropyl chitins with high degree of acetylation were synthesized using a mild method and characterized in terms of their structure and properties. The sulfopropyl chitins showed good solubility and self-assembly behavior in water, and they could form smart hydrogels at body temperature. Furthermore, they exhibited good biocompatibility, making them suitable for biomedical applications.
CARBOHYDRATE RESEARCH
(2023)
Article
Polymer Science
Yihao Zhang, Ruijia Liu, He Li, You Li, Xinqi Liu
Summary: This study investigated the interaction between 0.1 wt% soybean trypsin inhibitor (STI) and different concentrations of chitosan (CS) in aqueous solutions under different pH conditions. The formation of soluble/insoluble complexes between STI and CS was observed through hydrophobic or electrostatic interactions. The study also discussed the protective effect of the complexes on STI stability in simulated gastric juice. The results provide theoretical references for the development of supramolecular-structured carrier substances based on CS and STI.
Article
Chemistry, Multidisciplinary
Chuhong Yu, Jing Peng, Jiuqiang Li, Maolin Zhai
Summary: A facile and green method for preparing pH-responsive hollow polymeric microspheres was introduced in this study. The hollow microspheres exhibit obvious pH stimuli-responsiveness and reversible morphology transition, making them potentially suitable for a wide range of applications. The microspheres can release encapsulated hydrophobic molecules when the pH is higher than 5.0.
APPLIED SCIENCES-BASEL
(2021)
Article
Polymer Science
Shirin Naserifar, Petrus F. Kuijpers, Sylwia Wojno, Roland Kadar, Diana Bernin, Merima Hasani
Summary: This study investigates the effect of different bases on the solubility, reaction process, and product properties of cellulose etherification. The results show that using quaternary ammonium hydroxides as solvents can improve the solubility and reaction stability of cellulose, as well as reduce the degree of substitution. Sodium hydroxide, on the other hand, exhibits lower temperature stability and product solubility.
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)