N-acetyl cysteine protects anti-melanoma cytotoxic T cells from exhaustion induced by rapid expansion via the downmodulation of Foxo1 in an Akt-dependent manner

Efficacy of Adoptive T-cell Therapy Is Improved by Treatment with the Antioxidant N-Acetyl Cysteine, Which Limits Activation-Induced T-cell Death

(2016) M. J. Scheffel et al.   CANCER RESEARCH

Protective Effects of N-Acetylcysteine in Concanavalin A-Induced Hepatitis in Mice

(2015) Chengfen Wang et al.   MEDIATORS OF INFLAMMATION

Overcoming T cell exhaustion in infection and cancer

(2015) Kristen E. Pauken et al.   TRENDS IN IMMUNOLOGY

Cancer treatment and survivorship statistics, 2014

(2014) Carol E. DeSantis et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Promoting Thiol Expression Increases the Durability of Antitumor T-cell Functions

(2014) P. Kesarwani et al.   CANCER RESEARCH

Critical cysteines in Akt1 regulate its activity and proteasomal degradation: implications for neurodegenerative diseases

(2014) Faraz Ahmad et al.   FREE RADICAL BIOLOGY AND MEDICINE

The Transcription Factor FoxO1 Sustains Expression of the Inhibitory Receptor PD-1 and Survival of Antiviral CD8+ T Cells during Chronic Infection

(2014) Matthew M. Staron et al.   IMMUNITY

AntioxidantN-Acetylcysteine Protects Pancreatic β-Cells Against Aldosterone-Induced Oxidative Stress and Apoptosis in Femaledb/dbMice and Insulin-Producing MIN6 Cells

(2013) Hui Min Jin et al.   ENDOCRINOLOGY

N-Acetylcysteine and allopurinol up-regulated the Jak/STAT3 and PI3K/Akt pathways via adiponectin and attenuated myocardial postischemic injury in diabetes

(2013) Tingting Wang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Differential Localization of T-bet and Eomes in CD8 T Cell Memory Populations

(2013) L. M. McLane et al.   JOURNAL OF IMMUNOLOGY

Delay in oocyte aging in mice by the antioxidant N-acetyl-l-cysteine (NAC)

(2012) Jinmiao Liu et al.   HUMAN REPRODUCTION

Transcription Factor Foxo1 Represses T-bet-Mediated Effector Functions and Promotes Memory CD8+ T Cell Differentiation

(2012) Rajesh R. Rao et al.   IMMUNITY

Sorting Through Subsets

(2012) Christopher A. Klebanoff et al.   JOURNAL OF IMMUNOTHERAPY

Raising the Bar: The Curative Potential of Human Cancer Immunotherapy

(2012) S. A. Rosenberg   Science Translational Medicine

N-acetyl-L-cysteine increases acute graft-versus-host disease and promotes T-cell-mediated immunity in vitro

(2011) Helen Karlsson et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Genetic Engineering of Murine CD8+ and CD4+ T Cells for Preclinical Adoptive Immunotherapy Studies

(2011) Sid P. Kerkar et al.   JOURNAL OF IMMUNOTHERAPY

Costimulation Through the CD137/4-1BB Pathway Protects Human Melanoma Tumor-infiltrating Lymphocytes From Activation-induced Cell Death and Enhances Antitumor Effector Function

(2011) Jessica Ann Hernandez-Chacon et al.   JOURNAL OF IMMUNOTHERAPY

CD34-based enrichment of genetically engineered human T cells for clinical use results in dramatically enhanced tumor targeting

(2010) Håkan Norell et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

N-acetyl cysteine mitigates curcumin-mediated telomerase inhibition through rescuing of Sp1 reduction in A549 cells

(2010) I-Lun Hsin et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Tumor antigen-specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired

(2009) M. Ahmadzadeh et al.   BLOOD

The diversity of costimulatory and inhibitory receptor pathways and the regulation of antiviral T cell responses

(2009) Alison Crawford et al.   CURRENT OPINION IN IMMUNOLOGY

MART-1–Specific Melanoma Tumor-Infiltrating Lymphocytes Maintaining CD28 Expression Have Improved Survival and Expansion Capability Following Antigenic Restimulation In Vitro

(2009) Yufeng Li et al.   JOURNAL OF IMMUNOLOGY

Foxo1 links homing and survival of naive T cells by regulating L-selectin, CCR7 and interleukin 7 receptor

(2009) Yann M Kerdiles et al.   NATURE IMMUNOLOGY

Adoptive Cell Therapy for Patients With Metastatic Melanoma: Evaluation of Intensive Myeloablative Chemoradiation Preparative Regimens

(2008) Mark E. Dudley et al.   JOURNAL OF CLINICAL ONCOLOGY

Minimally Cultured Tumor-infiltrating Lymphocytes Display Optimal Characteristics for Adoptive Cell Therapy

(2008) Khoi Q. Tran et al.   JOURNAL OF IMMUNOTHERAPY