Catalase down-regulation in cancer cells exposed to arsenic trioxide is involved in their increased sensitivity to a pro-oxidant treatment

High-dose ascorbate and arsenic trioxide selectively kill acute myeloid leukemia and acute promyelocytic leukemia blasts in vitro

(2017) Nélida I. Noguera et al.   Oncotarget

SIRT2 Deacetylates and Inhibits the Peroxidase Activity of Peroxiredoxin-1 to Sensitize Breast Cancer Cells to Oxidant Stress-Inducing Agents

(2016) Warren Fiskus et al.   CANCER RESEARCH

Chromatin remodeling regulates catalase expression during cancer cells adaptation to chronic oxidative stress

(2016) Christophe Glorieux et al.   FREE RADICAL BIOLOGY AND MEDICINE

Overexpression of NAD(P)H:quinone oxidoreductase 1 (NQO1) and genomic gain of the NQO1 locus modulates breast cancer cell sensitivity to quinones

(2016) Christophe Glorieux et al.   LIFE SCIENCES

Melatonin enhances arsenic trioxide-induced cell death via sustained upregulation of Redd1 expression in breast cancer cells

(2016) Sun-Mi Yun et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Regulation of catalase expression in healthy and cancerous cells

(2015) Christophe Glorieux et al.   FREE RADICAL BIOLOGY AND MEDICINE

Catalase expression in MCF-7 breast cancer cells is mainly controlled by PI3K/Akt/mTor signaling pathway

(2014) Christophe Glorieux et al.   BIOCHEMICAL PHARMACOLOGY

Targeting Catalase but Not Peroxiredoxins Enhances Arsenic Trioxide-Induced Apoptosis in K562 Cells

(2014) Li-Li Song et al.   PLoS One

Metabolism of arsenic and its toxicological relevance

(2012) Takayuki Watanabe et al.   ARCHIVES OF TOXICOLOGY

Role of minimal residual disease monitoring in acute promyelocytic leukemia treated with arsenic trioxide in frontline therapy

(2012) E. Chendamarai et al.   BLOOD

ATRA plus arsenic gets another "A" in APL

(2012) J. H. Park   BLOOD

All-trans-retinoic acid, idarubicin, and IV arsenic trioxide as initial therapy in acute promyelocytic leukemia (APML4)

(2012) H. J. Iland et al.   BLOOD

The arsenic-based cure of acute promyelocytic leukemia promotes cytoplasmic sequestration of PML and PML/RARA through inhibition of PML body recycling

(2012) E. Lang et al.   BLOOD

Overexpression of GRP94 in breast cancer cells resistant to oxidative stress promotes high levels of cancer cell proliferation and migration: Implications for tumor recurrence

(2012) Nicolas Dejeans et al.   FREE RADICAL BIOLOGY AND MEDICINE

Catalase overexpression in mammary cancer cells leads to a less aggressive phenotype and an altered response to chemotherapy

(2011) Christophe Glorieux et al.   BIOCHEMICAL PHARMACOLOGY

Arsenic trioxide induces apoptosis of p53 null osteosarcoma MG63 cells through the inhibition of catalase

(2011) Yang Wang et al.   MEDICAL ONCOLOGY

Arsenic trioxide — An old drug rediscovered

(2010) Ashkan Emadi et al.   BLOOD REVIEWS

Ascorbate/menadione-induced oxidative stress kills cancer cells that express normal or mutated forms of the oncogenic protein Bcr-Abl. An in vitro and in vivo mechanistic study

(2010) Raphaël Beck et al.   INVESTIGATIONAL NEW DRUGS

Arsenic Trioxide Controls the Fate of the PML-RAR  Oncoprotein by Directly Binding PML

(2010) X. W. Zhang et al.   SCIENCE

Molecular Distinctions between Stasis and Telomere Attrition Senescence Barriers Shown by Long-term Culture of Normal Human Mammary Epithelial Cells

(2009) J. C. Garbe et al.   CANCER RESEARCH

In Situ Modulation of Oxidative Stress: A Novel and Efficient Strategy to Kill Cancer Cells

(2009) J. Verrax et al.   CURRENT MEDICINAL CHEMISTRY

Catalase activity and arsenic sensitivity in acute leukemia

(2008) Emma Coe et al.   LEUKEMIA & LYMPHOMA