Comparison of EpCAMhighCD44+ cancer stem cells with EpCAMhighCD44− tumor cells in colon cancer by single-cell sequencing

Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma

(2016) Itay Tirosh et al.   NATURE

Punctuated copy number evolution and clonal stasis in triple-negative breast cancer

(2016) Ruli Gao et al.   NATURE GENETICS

Identification of neutral tumor evolution across cancer types

(2016) Marc J Williams et al.   NATURE GENETICS

Activation of PKA leads to mesenchymal-to-epithelial transition and loss of tumor-initiating ability

(2016) D. R. Pattabiraman et al.   SCIENCE

Global cancer statistics, 2012

(2015) Lindsey A. Torre et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Distinct EMT programs control normal mammary stem cells and tumour-initiating cells

(2015) Xin Ye et al.   NATURE

A Big Bang model of human colorectal tumor growth

(2015) Andrea Sottoriva et al.   NATURE GENETICS

Interactive analysis and assessment of single-cell copy-number variations

(2015) Tyler Garvin et al.   NATURE METHODS

G&T-seq: parallel sequencing of single-cell genomes and transcriptomes

(2015) Iain C Macaulay et al.   NATURE METHODS

Somatic gene copy number alterations in colorectal cancer: new quest for cancer drivers and biomarkers

(2015) H Wang et al.   ONCOGENE

Quantitative assessment of single-cell whole genome amplification methods for detecting copy number variation using hippocampal neurons

(2015) Luwen Ning et al.   Scientific Reports

Colorectal Cancer Stem Cells: From the Crypt to the Clinic

(2014) Ann Zeuner et al.   Cell Stem Cell

Patterns of somatic alterations between matched primary and metastatic colorectal tumors characterized by whole-genome sequencing

(2014) Tao Xie et al.   GENOMICS

Clonal evolution in breast cancer revealed by single nucleus genome sequencing

(2014) Yong Wang et al.   NATURE

Single-Cell, Genome-wide Sequencing Identifies Clonal Somatic Copy-Number Variation in the Human Brain

(2014) Xuyu Cai et al.   Cell Reports

CCAT2, a novel noncoding RNA mapping to 8q24, underlies metastatic progression and chromosomal instability in colon cancer

(2013) H. Ling et al.   GENOME RESEARCH

Reproducible copy number variation patterns among single circulating tumor cells of lung cancer patients

(2013) X. Ni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-Wide Detection of Single-Nucleotide and Copy-Number Variations of a Single Human Cell

(2012) C. Zong et al.   SCIENCE

Monoclonal Antibodies Against Lgr5 Identify Human Colorectal Cancer Stem Cells

(2012) Kristel Kemper et al.   STEM CELLS

Single-cell dissection of transcriptional heterogeneity in human colon tumors

(2011) Piero Dalerba et al.   NATURE BIOTECHNOLOGY

BEDTools: a flexible suite of utilities for comparing genomic features

(2010) Aaron R. Quinlan et al.   BIOINFORMATICS

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

Aldehyde Dehydrogenase-Expressing Colon Stem Cells Contribute to Tumorigenesis in the Transition from Colitis to Cancer

(2009) J. E. Carpentino et al.   CANCER RESEARCH

CD44 is of Functional Importance for Colorectal Cancer Stem Cells

(2008) L. Du et al.   CLINICAL CANCER RESEARCH