LncRNA NEAT1/let-7a-5p axis regulates the cisplatin resistance in nasopharyngeal carcinoma by targeting Rsf-1 and modulating the Ras-MAPK pathway

Cisplatin can be safely administered to ovarian cancer patients with hypersensitivity to carboplatin

(2017) A. Bergamini et al.   GYNECOLOGIC ONCOLOGY

The long non-coding RNA NEAT1 enhances epithelial-to-mesenchymal transition and chemoresistance via the miR-34a/c-Met axis in renal cell carcinoma

(2017) Fei Liu et al.   Oncotarget

RSF1 regulates the proliferation and paclitaxel resistance via modulating NF-κB signaling pathway in nasopharyngeal carcinoma

(2017) Yong Liu et al.   Journal of Cancer

NEAT1, a long non-coding RNA, controls cell survival and is up-regulated in breast cancer

(2016) Z.A. Almnaseer et al.   EUROPEAN JOURNAL OF CANCER

Small molecule stabilization of the KSR inactive state antagonizes oncogenic Ras signalling

(2016) Neil S. Dhawan et al.   NATURE

Next generation deep sequencing identified a novel lncRNA n375709 associated with paclitaxel resistance in nasopharyngeal carcinoma

(2016) Shuling Ren et al.   ONCOLOGY REPORTS

Down-regulation of let-7a-5p predicts lymph node metastasis and prognosis in colorectal cancer: Implications for chemotherapy

(2016) Tsang-Pai Liu et al.   SURGICAL ONCOLOGY-OXFORD

Role of long non-coding RNA in tumor drug resistance

(2016) Heng Deng et al.   TUMOR BIOLOGY

The long non-coding RNA NEAT1 regulates epithelial to mesenchymal transition and radioresistance in through miR-204/ZEB1 axis in nasopharyngeal carcinoma

(2016) Yaoyong Lu et al.   TUMOR BIOLOGY

RAS/MAPK Activation Drives Resistance to Smo Inhibition, Metastasis, and Tumor Evolution in Shh Pathway-Dependent Tumors

(2015) X. Zhao et al.   CANCER RESEARCH

Let-7a regulates mammosphere formation capacity through Ras/NF-κB and Ras/MAPK/ERK pathway in breast cancer stem cells

(2015) Chongwen Xu et al.   CELL CYCLE

The Ras/MAPK pathway and hepatocarcinoma: pathogenesis and therapeutic implications

(2015) Bénédicte Delire et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Radiotherapy combined docetaxel and oxaliplatin chemotherapy is effective in patients with locally advanced nasopharyngeal carcinoma

(2015) Feng Pan et al.   MEDICAL ONCOLOGY

NEAT expression is associated with tumor recurrence and unfavorable prognosis in colorectal cancer

(2015) Yunlong Li et al.   Oncotarget

Inhibition of long non-coding RNA NEAT1 impairs myeloid differentiation in acute promyelocytic leukemia cells

(2014) Chengwu Zeng et al.   BMC CANCER

RSF1 Is a Positive Regulator of NF-κB–Induced Gene Expression Required for Ovarian Cancer Chemoresistance

(2014) Yeong-In Yang et al.   CANCER RESEARCH

Expanding the functional role of long noncoding RNAs

(2014) Per Johnsson et al.   CELL RESEARCH

Rsf-1 overexpression in human prostate cancer, implication as a prognostic marker

(2014) Hui Li et al.   TUMOR BIOLOGY

The oestrogen receptor alpha-regulated lncRNA NEAT1 is a critical modulator of prostate cancer

(2014) Dimple Chakravarty et al.   Nature Communications

Nasopharyngeal Carcinoma – A Retrospective Review of Demographics, Treatment and Patient Outcome in a Single Centre

(2013) R.J. Colaco et al.   CLINICAL ONCOLOGY

Long non-coding RNAs: modulators of nuclear structure and function

(2013) Jan H Bergmann et al.   CURRENT OPINION IN CELL BIOLOGY

CXCR4 downregulation of let-7a drives chemoresistance in acute myeloid leukemia

(2013) Ye Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

Rsf-1 overexpression correlates with poor prognosis and cell proliferation in colon cancer

(2012) Shuli Liu et al.   TUMOR BIOLOGY

Associations of Rsf-1 overexpression with poor therapeutic response and worse survival in patients with nasopharyngeal carcinoma

(2011) Hui-Chun Tai et al.   JOURNAL OF CLINICAL PATHOLOGY

MicroRNA let-7a represses chemoresistance and tumourigenicity in head and neck cancer via stem-like properties ablation

(2011) Cheng-Chia Yu et al.   ORAL ONCOLOGY

MicroRNA let-7 suppresses nasopharyngeal carcinoma cells proliferation through downregulating c-Myc expression

(2010) Thian-Sze Wong et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Functional Analysis of 11q13.5 Amplicon Identifies Rsf-1 (HBXAP) as a Gene Involved in Paclitaxel Resistance in Ovarian Cancer

(2009) Jung Hye Choi et al.   CANCER RESEARCH

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL