Zebrafish vitamin K epoxide reductases: expression in vivo, along extracellular matrix mineralization and under phylloquinone and warfarin in vitro exposure

Confirmation of warfarin resistance of naturally occurring VKORC1 variants by coexpression with coagulation factor IX and in silico protein modelling

(2014) Elisabeth Müller et al.   BMC GENETICS

Warfarin, a potential pollutant in aquatic environment acting through Pxr signaling pathway and γ-glutamyl carboxylation of vitamin K-dependent proteins

(2014) Ignacio Fernández et al.   ENVIRONMENTAL POLLUTION

Conserved Loop Cysteines of Vitamin K Epoxide Reductase Complex Subunit 1-like 1 (VKORC1L1) Are Involved in Its Active Site Regeneration

(2014) Jian-Ke Tie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dietary Supplementation with Vitamin K Affects Transcriptome and Proteome of Senegalese Sole, Improving Larval Performance and Quality

(2014) Nadège Richard et al.   MARINE BIOTECHNOLOGY

Functional characterization of a full length pregnane X receptor, expression in vivo, and identification of PXR alleles, in Zebrafish (Danio rerio)

(2013) Afonso C.D. Bainy et al.   AQUATIC TOXICOLOGY

Calumenin has a role in the alleviation of ER stress in neonatal rat cardiomyocytes

(2013) Joo Hee Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Human VKORC1 mutations cause variable degrees of 4-hydroxycoumarin resistance and affect putative warfarin binding interfaces

(2013) K. J. Czogalla et al.   BLOOD

The Vitamin K Oxidoreductase Is a Multimer That Efficiently Reduces Vitamin K Epoxide to Hydroquinone to Allow Vitamin K-dependent Protein Carboxylation

(2013) Mark A. Rishavy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

VKORC1L1, an Enzyme Rescuing the Vitamin K 2,3-Epoxide Reductase Activity in Some Extrahepatic Tissues during Anticoagulation Therapy

(2013) Abdessalem Hammed et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Retinoic acid differentially affects in vitro proliferation, differentiation and mineralization of two fish bone-derived cell lines: Different gene expression of nuclear receptors and ECM proteins

(2013) Ignacio Fernández et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Development of an In Vitro Cell System from Zebrafish Suitable to Study Bone Cell Differentiation and Extracellular Matrix Mineralization

(2013) Parameswaran Vijayakumar et al.   Zebrafish

Skeletal anomalies in reared European fish larvae and juveniles. Part 1: normal and anomalous skeletogenic processes

(2013) Clara Boglione et al.   Reviews in Aquaculture

Skeletal anomalies in reared European fish larvae and juveniles. Part 2: main typologies, occurrences and causative factors

(2013) Clara Boglione et al.   Reviews in Aquaculture

Nuclear receptors in the multidrug resistance through the regulation of drug-metabolizing enzymes and drug transporters

(2012) Yakun Chen et al.   BIOCHEMICAL PHARMACOLOGY

Human Vitamin K Epoxide Reductase and Its Bacterial Homologue Have Different Membrane Topologies and Reaction Mechanisms

(2012) Jian-Ke Tie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Vitamin K and the Nervous System: An Overview of its Actions

(2012) Guylaine Ferland   Advances in Nutrition

Vitamin K in fish nutrition

(2011) C. KROSSØY et al.   AQUACULTURE NUTRITION

Inhibition of osteoblastic differentiation by warfarin and 18-α-glycyrrhetinic acid

(2011) Hyung Min Jeong et al.   ARCHIVES OF PHARMACAL RESEARCH

Characterization of calumenin in mouse heart

(2011) Sanjaya Kumar Sahoo et al.   BMB Reports

Human Vitamin K 2,3-Epoxide Reductase Complex Subunit 1-like 1 (VKORC1L1) Mediates Vitamin K-dependent Intracellular Antioxidant Function

(2011) Philipp Westhofen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

T-Coffee: a web server for the multiple sequence alignment of protein and RNA sequences using structural information and homology extension

(2011) P. Di Tommaso et al.   NUCLEIC ACIDS RESEARCH

Developmental effects of coumarin and the anticoagulant coumarin derivative warfarin on zebrafish (Danio rerio) embryos

(2011) Stefan Weigt et al.   REPRODUCTIVE TOXICOLOGY

Fish bone-derived cell lines: an alternativein vitrocell system to study bone biology

(2010) M. S. Rafael et al.   JOURNAL OF APPLIED ICHTHYOLOGY

Novel Insight into the Mechanism of the Vitamin K Oxidoreductase (VKOR)

(2010) Mark A. Rishavy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pregnane X receptor knockout mice display osteopenia with reduced bone formation and enhanced bone resorption

(2010) Kotaro Azuma et al.   JOURNAL OF ENDOCRINOLOGY

Thirteen novel VKORC1 mutations associated with oral anticoagulant resistance: insights into improved patient diagnosis and treatment

(2010) M. WATZKA et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Vitamin K epoxide reductase prefers ER membrane-anchored thioredoxin-like redox partners

(2010) S. Schulman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vitamin K promotes mineralization, osteoblast-to-osteocyte transition, and an anticatabolic phenotype by γ-carboxylation-dependent and -independent mechanisms

(2009) Gerald J. Atkins et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Novel mutations in the VKORC1 gene of wild rats and mice - a response to 50 years of selection pressure by warfarin?

(2009) Simone Rost et al.   BMC GENETICS

Vitamin K-dependent γ-glutamylcarboxylase in Atlantic salmon (Salmo salar L.)

(2009) Christel Krossøy et al.   FISH PHYSIOLOGY AND BIOCHEMISTRY

Vitamin K in Parenteral Nutrition

(2009) Martin J. Shearer   GASTROENTEROLOGY

Characterization of Calumenin-SERCA2 Interaction in Mouse Cardiac Sarcoplasmic Reticulum

(2009) Sanjaya Kumar Sahoo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dietary menadione nicotinamide bisulphite (vitamin K3) does not affect growth or bone health in first-feeding fry of Atlantic salmon (Salmo salarL.)

(2008) C. KROSSØY et al.   AQUACULTURE NUTRITION

Evolution of pharmacologic specificity in the pregnane X receptor

(2008) Sean Ekins et al.   BMC EVOLUTIONARY BIOLOGY