Inventing new therapies without reinventing the wheel: the power of drug repurposing

Revisiting Repurposing

(2016) Elizabeth R. Sharlow   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Development of a stretch-induced neurotrauma model for medium-throughput screening in vitro : identification of rifampicin as a neuroprotectant

(2016) Isabel López-García et al.   BRITISH JOURNAL OF PHARMACOLOGY

Repurposing of approved cardiovascular drugs

(2016) Junichi Ishida et al.   Journal of Translational Medicine

Can you teach old drugs new tricks?

(2016) Nicola Nosengo   NATURE

Identification of drug candidates and repurposing opportunities through compound–target interaction networks

(2015) Anna Cichonska et al.   Expert Opinion on Drug Discovery

Drug repurposing in oncology—patient and health systems opportunities

(2015) Francesco Bertolini et al.   Nature Reviews Clinical Oncology

An analysis of the attrition of drug candidates from four major pharmaceutical companies

(2015) Michael J. Waring et al.   NATURE REVIEWS DRUG DISCOVERY

Drug repurposing and the prior art patents of competitors

(2014) Christian Sternitzke   DRUG DISCOVERY TODAY

Drug Repurposing: Translational Pharmacology, Chemistry, Computers and the Clinic

(2013) Naiem Issa et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Toward better drug repositioning: prioritizing and integrating existing methods into efficient pipelines

(2013) Guangxu Jin et al.   DRUG DISCOVERY TODAY

How can attrition rates be reduced in cancer drug discovery?

(2013) Lucas Moreno et al.   Expert Opinion on Drug Discovery

Diagnosing the decline in pharmaceutical R&D efficiency

(2012) Jack W. Scannell et al.   NATURE REVIEWS DRUG DISCOVERY

Prediction of Drug-Target Interactions and Drug Repositioning via Network-Based Inference

(2012) Feixiong Cheng et al.   PLoS Computational Biology

Drug repurposing and adverse event prediction using high-throughput literature analysis

(2011) Spyros N. Deftereos et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine