Review
Fisheries
Hanover Matz, Danish Munir, James Logue, Helen Dooley
Summary: Cartilaginous fishes, including chimeras, sharks, skates, and rays, split from the common ancestor with other jawed vertebrates around 450 million years ago. They are the oldest extant taxonomic group with an Ig-based adaptive immune system, and research has revealed the conservation and taxon-specific characteristics of Igs, as well as significant progress in analyzing genomic and transcriptomic data sets. Functional studies have further enhanced our understanding of Ig and humoral response in sharks and their relatives, but there are still areas where knowledge is lacking.
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
(2021)
Article
Engineering, Marine
Yaxin Wu, Zhao Jia, Huifeng Dang, Hehe Xiao, Wenji Huang, Qin Liu, Kangyong Chen, Lei Zhang, Jun Zou, Junya Wang
Summary: The study identified the tumor necrosis superfamily (TNFSF) and their receptors (TNFRs) in spotted gar, showing their crucial role in inflammatory responses. The genes have conserved structure and expression similar to their homologs in zebrafish and humans, involved in immune response and expanding knowledge on the TNF system in primitive ray-finned fish.
JOURNAL OF MARINE SCIENCE AND ENGINEERING
(2022)
Review
Nutrition & Dietetics
Franklin Chamorro, Paz Otero, Maria Carpena, Maria Fraga-Corral, Javier Echave, Sepidar Seyyedi-Mansour, Lucia Cassani, Miguel A. Prieto
Summary: Oily fish is a rich source of nutrients, including energy, proteins, lipids, vitamins, and minerals. Long-chain omega-3 polyunsaturated fatty acids (DHA and EPA) in oily fish play a beneficial role in promoting health and preventing various diseases. Oily fish consumption is important throughout the human lifespan. However, the presence of chemical pollutants in oily fish can pose health risks, especially for vulnerable groups like pregnant women and young children.
Article
Biology
Maria Antonella Zingaropoli, Patrizia Pasculli, Matteo Tartaglia, Federica Dominelli, Federica Ciccone, Ambra Taglietti, Valentina Perri, Leonardo Malimpensa, Gina Ferrazzano, Marco Iannetta, Cosmo Del Borgo, Miriam Lichtner, Claudio Maria Mastroianni, Antonella Conte, Maria Rosa Ciardi
Summary: In ocrelizumab-treated people with multiple sclerosis (pwMS), an increase in infectious events is associated with higher levels of BAFF. Therefore, BAFF may serve as a marker for immune dysfunction and infectious risk.
Article
Food Science & Technology
Wen Li, Kazuhiro Ura, Yasuaki Takagi
Summary: Cartilage is mainly composed of proteoglycans and collagen. Bioactive compounds derived from animal cartilage have multiple bioactivities and are incorporated in popular health products. The aging population and increase in degenerative and chronic diseases will drive the market demand for cartilage products. Fish-derived cartilage products have gained attention due to their high level of safety and other activities. This review summarizes the research into fish-derived cartilage products and discusses future trends and tasks.
CURRENT RESEARCH IN FOOD SCIENCE
(2022)
Article
Oncology
Le Ying, Phoebe Liu, Zhoujie Ding, Georgie Wray-McCann, Jack Emery, Nina Colon, Lena H. M. Le, Le Son Tran, Ping Xu, Liang Yu, Dana J. Philpott, Yugang Tu, Daryl M. Z. Cheah, Chee L. Cheng, Soon T. Lim, Choon K. Ong, Richard L. Ferrero
Summary: This study established a new mouse model to study gastric MALT lymphoma and found that mice with a myeloid-specific deletion of Nlrc5 develop precursor B-cell lesions to MALT lymphoma after Helicobacter infection in a shorter time. The lesions in these mice have similar histopathological features to the human disease and are accompanied by an immunosuppressive tissue microenvironment. The study also demonstrated that anti-CD40L antibody can prevent gastric B-cell lesions in mice and reduce the number of immune cells in the stomach.
JOURNAL OF PATHOLOGY
(2023)
Review
Immunology
Hope Steele, Jason Cheng, Ashley Willicut, Garrison Dell, Joey Breckenridge, Erica Culberson, Andrew Ghastine, Virginie Tardif, Rana Herro
Summary: Fibrosis, resulting from extracellular matrix protein deposition, is a leading cause of death in the USA. Therapeutic options targeting the tumor necrosis super family (TNFSF) members show promise in degrading or reversing fibrosis in various organs. This review provides insights into the involvement of TNFSF in fibrosis and emphasizes the importance of targeting this superfamily to improve current therapies.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Biology
Milton Tan, Anthony K. Redmond, Helen Dooley, Ryo Nozu, Keiichi Sato, Shigehiro Kuraku, Sergey Koren, Adam M. Phillippy, Alistair D. M. Dove, Timothy Read
Summary: This study reported the long-read sequencing of the whale shark genome, providing the best chondrichthyan genome assembly and studying the genomic evolution of ancestral gene families, immunity, and giant vertebrates. The research found a significant increase in gene families at the origin of jawed vertebrates.
Article
Cell Biology
Ismael Hernandez-Nunez, Diego Robledo, Helene Mayeur, Sylvie Mazan, Laura Sanchez, Fatima Adrio, Anton Barreiro-Iglesias, Eva Candal
Summary: Neurogenesis is the process of generating new neurons by progenitor cells, which is restricted to specific neurogenic niches. The retina of cartilaginous fish such as catsharks shows active proliferation and neurogenesis in juveniles but a reduction in cell proliferation after sexual maturation. RNA-Seq analysis revealed a decrease in gene expression related to cell proliferation and neurogenesis in adult catsharks, providing valuable insight into signaling pathways controlling neurogenesis in vertebrate retinas.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Article
Green & Sustainable Science & Technology
Xela Garcia-Santiago, Amaya Franco-Uria, Luis T. Antelo, Jose A. Vazquez, Ricardo Perez-Martin, M. Teresa Moreira, Gumersindo Feijoo
Summary: Fishing activities produce discards that could potentially be used to extract high-added value bio-compounds, but this valorization strategy may have varying environmental impacts. An eco-efficiency assessment is necessary to determine the most suitable processes for planning valorization strategies.
JOURNAL OF INDUSTRIAL ECOLOGY
(2021)
Article
Automation & Control Systems
Shuaizheng Yan, Zhengxing Wu, Jian Wang, Sijie Li, Min Tan, Junzhi Yu
Summary: This study explores the distinctive rolled swimming motion mode of the hammerhead shark through a biomimetic robotic hammerhead shark. By constructing a scaled-down robotic prototype and establishing kinematics and dynamics models, the impact of the long dorsal fin and rolling state on swimming performance is investigated. Extensive aquatic experiments demonstrate that the proposed rolled motion significantly improves locomotion performance and propulsive efficiency of the robotic hammerhead shark.
IEEE-ASME TRANSACTIONS ON MECHATRONICS
(2023)
Article
Automation & Control Systems
Shuaizheng Yan, Zhengxing Wu, Jian Wang, Yupei Huang, Min Tan, Junzhi Yu
Summary: In this article, a feasible real-world deep reinforcement learning framework for autonomous underwater exploration of robotic fish is proposed, which improves data sampling efficiency and control performance through three training phases. Extensive experiments on a novel biomimetic robotic shark show that this method significantly improves the safety and efficiency of autonomous exploration based on local sensor information.
IEEE TRANSACTIONS ON INDUSTRIAL ELECTRONICS
(2023)
Article
Engineering, Marine
Angela Carluccio, Francesca Capezzuto, Porzia Maiorano, Letizia Sion, Gianfranco D'Onghia
Summary: Baited lander is a low-impact technique for collecting data on cartilaginous fish diversity and abundance, and this study compared the distribution and abundance of cartilaginous fish in two geographic areas. Differences in assemblages were detected in the same area using different sampling tools, while no significant differences were found among different areas explored with the same method.
JOURNAL OF MARINE SCIENCE AND ENGINEERING
(2021)
Article
Multidisciplinary Sciences
Mark Royer, Carl Meyer, John Royer, Kelsey Maloney, Edward Cardona, Chloe Blandino, Guilherme Fernandes da Silva, Kate Whittingham, Kim N. Holland
Summary: The tropical scalloped hammerhead shark prevents convective heat loss at the gills during dives into cold water by suppressing gill function.
Article
Multidisciplinary Sciences
Tamar Poppelier, Jana Bonsberger, Boris Woody Berkhout, Renee Pollmanns, Vera Schluessel
Summary: This study explores the acoustic discrimination abilities of grey bamboo sharks and finds that they can learn tasks through both visual and acoustic stimuli. The results show that grey bamboo sharks can distinguish between two sounds within a frequency range of 90-210 Hz, with a minimum frequency difference of 20-30 Hz leading to behavioral changes. Research on shark acoustic abilities is crucial for the management and conservation efforts of sharks.
SCIENTIFIC REPORTS
(2022)
Review
Immunology
Katherine M. Buckley, Helen Dooley
Summary: The ongoing arms race between hosts and microbes has driven the evolution of novel strategies for diversifying immune response molecules. Different organisms have different mechanisms for generating and maintaining diversity. In addition to pathogen detection, immunological diversity also plays important roles in allorecognition systems.
JOURNAL OF IMMUNOLOGY
(2022)
Article
Immunology
Fiona K. Bakke, Manu Kumar Gundappa, Hanover Matz, David A. Stead, Daniel J. Macqueen, Helen Dooley
Summary: This study used mass spectrometry-based proteomics to identify and quantify candidate immune proteins in the plasma of nurse sharks. By integrating transcriptome data, they identified 626 plasma proteins and discovered some proteins involved in the immune response. This research enhances genetic and protein-level resources for nurse shark research and improves our understanding of elasmobranch plasma proteome.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Chemistry, Analytical
Kritika Srinivasan Rajsri, Michael P. McRae, Glennon W. Simmons, Nicolaos J. Christodoulides, Hanover Matz, Helen Dooley, Akiko Koide, Shohei Koide, John T. McDevitt
Summary: This article introduces a rapid diagnostic method that can quantitatively measure SARS-CoV-2 antibodies. This method could help clinicians make decisions on booster shots and assess convalescent plasma donors, as well as enable researchers to measure antibody levels against new viral variants in immunized or infected individuals.
Article
Immunology
Anthony K. Redmond, Rita Pettinello, Fiona K. Bakke, Helen Dooley
Summary: In this study, the TNFSF repertoires of five cartilaginous fish genomes were analyzed. It was found that sharks have more TNFSF genes, with about 30 genes, compared to any other vertebrate species. This suggests that the ancestral jawed vertebrate had a larger and more diverse TNFSF repertoire than previously thought, challenging the notion that the cartilaginous fish immune system is primitive compared to mammals.
JOURNAL OF IMMUNOLOGY
(2022)
Article
Fisheries
Eakapol Wangkahart, Areerat Thongsrisuk, Regis Vialle, Sirinya Pholchamat, Phitcharat Sunthamala, Janjira Phudkliang, Prapansak Srisapoome, Tiehui Wang, Christopher J. Secombes
Summary: This study aimed to compare the potential of two adjuvanted-bacterial vaccines (SAIV) against Streptococcus agalactiae, determine their effectiveness in improving protection, and analyze the involved immune mechanisms. The results showed that MontanideTM ISA 763A VG and MontanideTM ISA 763B VG have the potential to be used as adjuvants for fish vaccines against streptococcosis, as evidenced by the enhanced immunoprotection seen when given in combination with the SAIV vaccine employed in this study.
FISH & SHELLFISH IMMUNOLOGY
(2023)
Correction
Multidisciplinary Sciences
Anthony K. Redmond, Aoife McLysaght
NATURE COMMUNICATIONS
(2022)
Article
Fisheries
Fuguo Liu, Brian Dixon, Maria del Mar Ortega-Villaizan, Carolina Tafalla, Hongsen Xu, Christopher J. Secombes, Tiehui Wang
Summary: This study compared the gene expression profiles of proinflammatory and regulatory cytokines in eight different rainbow trout cell lines, including three epithelial cell lines, one endothelial cell line, one fibroblast cell line, two stromal cell lines, and one monocyte/macrophage-like cell line. The study found that certain cytokines were mainly expressed in leukocytes, while others were not expressed in these cells. The investigation of these cell lines provides a valuable database for studying cytokine function in fish and confirms the phenotypic relationship of these cell types at the molecular level.
FISH & SHELLFISH IMMUNOLOGY
(2023)
Letter
Multidisciplinary Sciences
Anthony K. Redmond, Aoife McLysaght
NATURE COMMUNICATIONS
(2023)
Article
Multidisciplinary Sciences
Anthony K. Redmond, Dearbhaile Casey, Manu Kumar Gundappa, Daniel J. Macqueen, Aoife McLysaght
Summary: Whole genome duplication (WGD) is an important event in evolution, generating new genes and potentially promoting survival during mass extinctions. Paddlefish and sturgeon, sister lineages, show genomic evidence of ancient WGD. Although the duplications appear to be independent, they actually stem from a shared WGD event over 200 million years ago, prior to the Permian-Triassic extinction. The shared WGD is masked by lineage divergence before the completion of rediploidization.
NATURE COMMUNICATIONS
(2023)
Article
Biotechnology & Applied Microbiology
Kritika Srinivasan Rajsri, Michael P. McRae, Nicolaos J. Christodoulides, Isaac Dapkins, Glennon W. Simmons, Hanover Matz, Helen Dooley, David Fenyo, John T. McDevitt
Summary: As COVID-19 public health measures are being eased globally, the emergence of new SARS-CoV-2 strains continues to pose a high risk for vulnerable populations. The waning of antibody-mediated protection acquired from vaccination and/or infection and the ineffectiveness of monoclonal antibody prophylaxis in immunocompromised populations necessitate the monitoring of new variants and their impact on vaccine performance. Screening methods such as surveillance of new SARS-CoV-2 infections and serology testing are gaining consensus, particularly for at-risk groups.
BIOENGINEERING-BASEL
(2023)
Letter
Multidisciplinary Sciences
Anthony K. Redmond, Aoife McLysaght
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2023)
Article
Cell Biology
Hanover Matz, Richard S. Taylor, Anthony K. Redmond, Thomas M. Hill, Rose Ruiz Daniels, Mariana Beltran, Neil C. Henderson, Daniel J. Macqueen, Helen Dooley
Summary: By studying the spleens of nurse sharks, we found that sharks are capable of producing robust antigen-specific responses and affinity maturation of B cells, despite the absence of germinal centers (GCs) observed in other animals. We also identified immune-related marker gene expression in the spleen cells of sharks and tracked their localization in the splenic follicles. These findings provide insights into the evolutionary foundation of GCs.
Meeting Abstract
Immunology
Hanover C. Matz, Helen Dooley
JOURNAL OF IMMUNOLOGY
(2022)
