Article
Economics
Ian Grady, Sean Grady, Nailya Chanisheva
Summary: This study found that the 10-year treatment cost of female Medicare beneficiaries with breast cancer increases with increasing stage at diagnosis. Any effective screening technology that reduces stage at diagnosis will result in significant treatment cost savings to the Medicare program.
EUROPEAN JOURNAL OF HEALTH ECONOMICS
(2021)
Article
Oncology
Ronda Copher, Arianna Kee, Aaron Gerds
Summary: Myelofibrosis results in increased resource utilization and costs for patients and the US healthcare system. This study provides insights into treatment patterns, healthcare resource utilization, and costs associated with myelofibrosis, particularly in patients treated with ruxolitinib.
Article
Gastroenterology & Hepatology
Calvin X. Geng, Anuragh R. Gudur, Mark Radlinski, Ross C. D. Buerlein, Daniel S. Strand, Bryan G. Sauer, Vanessa M. Shami, Andrew Y. Wang, Alexander Podboy
Summary: Lower socioeconomic status is associated with higher cancer-specific mortality and lower rates of endoscopic resection in early esophageal adenocarcinoma.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Article
Agriculture, Dairy & Animal Science
Michael R. Donnelly, Amy R. Hazel, Leslie B. Hansen, Bradley J. Heins
Summary: Health treatments of Holstein cows were recorded and classified into five categories. The highest cost of health treatments occurred during the first 30 days in milk and varied depending on parity. The total health treatment cost differed among herds and usually increased with parity.
Article
Oncology
Scarlett Hao, Anastasios Mitsakos, Patrycja Popowicz, William Irish, Rebecca A. Snyder, Alexander A. Parikh
Summary: This study found that the Affordable Care Act (ACA) led to an increase in the early detection of pancreatic ductal adenocarcinoma (PDAC). However, racial, insurance, and socioeconomic treatment disparities still persist.
JOURNAL OF SURGICAL ONCOLOGY
(2022)
Article
Oncology
Alessandra Buja, Claudia Cozzolino, Anna Zanovello, Ruggero Geppini, Andrea Miatton, Manuel Zorzi, Mariagiovanna Manfredi, Emanuela Bovo, Paolo Del Fiore, Saveria Tropea, Luigi dall'Olmo, Carlo Riccardo Rossi, Simone Mocellin, Marco Rastrelli, Massimo Rugge
Summary: The aim of this study was to analyze the cost items of CMM based on stage at diagnosis and other diagnostic and prognostic characteristics. Direct melanoma-related costs per patient were calculated and stratified by cost items. The study found that the highest costs for CMM patients are in the first year after diagnosis, with hospitalization costs being significantly higher compared to subsequent years. Outpatient services and inpatient drug costs decrease gradually over time. The higher expenditure associated with advanced stages of CMM is mainly due to inpatient drug use.
FRONTIERS IN ONCOLOGY
(2023)
Article
Infectious Diseases
Ornella Masimbi, Janna M. Schurer, Ellen Rafferty, Jean D' Amour Ndahimana, J. Hellen Amuguni
Summary: The direct medical costs incurred by the Ministry of Health in diagnosing and treating malaria in three districts of Rwanda in 2018 totaled USD 645,647.68. Severe malaria results in much higher expenses compared to other malaria types, emphasizing the importance of prompt diagnosis and appropriate treatment to prevent progression to severe malaria.
Article
Medicine, General & Internal
Anirudh Saraswathula, Samantha J. Merck, Ge Bai, Christine M. Weston, Elizabeth Ann Skinner, April Taylor, Allen Kachalia, Renee Demski, Albert W. Wu, Stephen A. Berry
Summary: US hospitals report data on many health care quality metrics, but the cost of data collection and reporting, independent of quality-improvement efforts, is not well known. This study evaluated inpatient quality metrics for adult patients and estimated the cost of data collection and reporting. The results showed that significant resources are expended exclusively for quality reporting, and some methods of quality assessment are far more expensive than others.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2023)
Article
Cardiac & Cardiovascular Systems
Smita Sihag, Sergio De La Torre, Meier Hsu, Tamar Nobel, Kay See Tan, Hans Gerdes, Pari Shah, Manjit Bains, David R. Jones, Daniela Molena
Summary: In patients with pathologic T1 esophageal adenocarcinoma, nodal involvement and tumor length are independent risk factors for recurrence, whereas tumors <2 cm in length without lymphovascular invasion are associated with a low risk of recurrence.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2021)
Article
Oncology
Jingxuan Zhao, Xuesong Han, Leticia Nogueira, Stacey A. Fedewa, Ahmedin Jemal, Michael T. Halpern, K. Robin Yabroff
Summary: Previous studies have shown that uninsured patients in the United States are more likely to be diagnosed with late-stage cancer and have worse survival rates. This report provides comprehensive data on the association between health insurance coverage type and stage at diagnosis and long-term survival in individuals diagnosed with common cancers between 2010 and 2013.
CA-A CANCER JOURNAL FOR CLINICIANS
(2022)
Article
Surgery
Djhenne Dalmacy, Alessandro Paro, J. Madison Hyer, Samilia Obeng-Gyasi, Timothy M. Pawlik
Summary: This study aims to determine the impact of county-level upward economic mobility on stage at diagnosis and receipt of treatment among pancreatic adenocarcinoma patients. The study found that patients from areas with higher economic mobility were more likely to be diagnosed at an earlier stage as well as receive surgery or chemotherapy. However, the impact of economic mobility on Black patients was smaller.
Article
Economics
Lorna Wills, Diana Nagarwalla, Clare Pearson, Sean Mcphail, Rose Hinchliffe, Ben Sharpless, Fahmina Fardus-Reid, Lyndsy Ambler, Samantha Harrison, Jon Shelton
Summary: Based on the data from England's National Cancer Registration Dataset and matched hospital, radiotherapy and SACT data, the costs of initial cancer treatment were calculated. It was found that the treatment costs for breast, colon, and rectal cancers increased with later stage at diagnosis, while the costs for lung and prostate cancers were lower at stages 1 and 4. Surgery and SACT were the most expensive treatments.
EUROPEAN JOURNAL OF HEALTH ECONOMICS
(2023)
Article
Oncology
Oluwadamilola T. Oladeru, Christa M. Lam, Muhammad M. Qureshi, Ariel E. Hirsch, Kimberley S. Mak, Michael A. Dyer, Minh Tam Truong
Summary: This study retrospectively reviewed the demographic and clinicopathologic characteristics of incarcerated individuals who received radiation therapy at a large safety-net hospital. The results showed that most incarcerated cancer patients were male, older, and were at advanced stages at the time of diagnosis, with low follow-up rates. This study highlights the inequalities in cancer stage at diagnosis among incarcerated patients.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
(2023)
Article
Public, Environmental & Occupational Health
Fahra Rajabali, Kate Turcotte, Alex Zheng, Nick Pauls, Tony Nguyen, Evelyn Kalman, Vedrana Covic, Ian Pike
Summary: This study quantified the total cost of violent firearm-related offenses in British Columbia from 2012 to 2016, estimating direct costs to the health care system, indirect costs to society, and criminal justice system costs. The study found a total of 108 deaths and 245 hospitalizations resulting from violent firearm injuries, with an average annual cost of $294,378,985. The costs were significantly higher in the criminal justice system than in health care.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Green & Sustainable Science & Technology
Ghina Elhaffar, Fabien Durif, Dilip Soman, Laurette Dube
Summary: This study conceptualizes and organizes the perceived green costs and develops a measurement scale for them. The authors find that people perceive nine types of green costs, which are further divided into nine first-order constructs. The Perceived Green Costs Scale demonstrates reliability, internal consistency, and convergent and divergent validity. The findings show that the Switching Costs construct mediates between green attitude and green behavior, contributing to the theory of planned behavior. The study provides insights into the green behavioral gap and behavioral frictions in sustainable consumption and offers implications for brand managers, customer experience architects, educators, and consumers in promoting a more sustainable future.
JOURNAL OF CLEANER PRODUCTION
(2023)
Article
Substance Abuse
Dolly Baliunas, Peter Selby, Claire de Oliveira, Paul Kurdyak, Laura Rosella, Laurie Zawertailo, Longdi Fu, Rinku Sutradhar
Summary: This study aimed to assess the impact of smoking cessation treatment on subsequent healthcare service use in a general primary care patient population. The results showed that patients who accessed smoking cessation treatment had slightly higher rates of outpatient visits, emergency department visits, and hospitalizations over a 5-year follow-up period.
Article
Environmental Sciences
Chidchanok Ruengorn, Ratanaporn Awiphan, Chabaphai Phosuya, Yongyuth Ruanta, Kednapa Thavorn, Nahathai Wongpakaran, Tinakon Wongpakaran, Surapon Nochaiwong
Summary: This study aimed to determine the disparities and factors associated with COVID-19-related public stigma in the Thai population. The results showed that middle-aged or older adults, males, divorced/widowed/separated individuals, those under current quarantine, those with moderate/severe fear of COVID-19, and those with medium/high perceived risk of COVID-19 were the main risk factors associated with a moderate and high degree of COVID-19-related public stigma. Additional risk factors related to a high degree of COVID-19-related public stigma were religion (Buddhist), region of residence (non-capital city), and exposure to COVID-19-related information.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Review
Genetics & Heredity
Mati Chuamanochan, Sutthinee Phuprasertsak, Puncharas Weesasubpong, Chidchanok Ruengorn, Chabaphai Phosuya, Ratanaporn Awiphan, Brian Hutton, Kednapa Thavorn, Jonathan A. Bernstein, Surapon Nochaiwong
Summary: This study aims to conduct a systematic review and network meta-analysis to identify the best evidence-based treatments for the management of acute attacks and prophylaxis of hereditary angioedema (HAE). The study will include both parallel and crossover randomized controlled trials and search multiple electronic databases for relevant trials. The results will be synthesized using pairwise and network meta-analysis methods, considering the effect sizes, evidence certainty, and ranking of treatment effects.
Article
Medicine, General & Internal
Wei Fang Dai, Jaclyn M. Beca, Chenthila Nagamuthu, Ning Liu, Claire de Oliveira, Craig C. Earle, Maureen Trudeau, Rebecca E. Mercer, Kelvin K. W. Chan
Summary: This study aimed to evaluate the real-world effectiveness and safety of pertuzumab in patients with metastatic breast cancer. The results showed that pertuzumab treatment was associated with a significant improvement in overall survival and a lower incidence of hospitalization compared to the control group.
Article
Medicine, General & Internal
Faizan Khan, Kednapa Thavorn, Doug Coyle, Sasha van Katwyk, Tobias Tritschler, Brian Hutton, Gregoire Le Gal, Marc Rodger, Dean Fergusson
Summary: This study aims to assess the differences in clinical benefits, harms, and costs of stopping versus continuing anticoagulant therapy indefinitely for a first unprovoked venous thromboembolism (VTE). A probabilistic Markov model will be developed to estimate life-years, quality-adjusted life-years, costs, and incremental cost-effectiveness ratios. The results will be disseminated through conferences and a peer-reviewed journal.
Article
Economics
Maya Murmann, Danielle Sinden, Amy T. T. Hsu, Kednapa Thavorn, Anan Bader Eddeen, Annie H. H. Sun, Benoit Robert
Summary: A nursing home-based transitional care unit can reduce hospital length of stay and the risk of subsequent institutionalization among frail, older adults. It is a more cost-effective model of care and allows older adults to stay at home for a longer period without institutional care. This research supports the investment in nursing home-based transitional care programs.
JOURNAL OF MEDICAL ECONOMICS
(2023)
Article
Substance Abuse
Alyssa Grant, Chia Jie Tan, Somkiat Wattanasirichaigoon, Suthat Rungruanghiranya, Araya Thongphiew, Kednapa Thavorn, Nathorn Chaiyakunapruk
Summary: The cost-effectiveness of the SMART Quit Clinic Program (FAHSAI Clinic) in Thailand was assessed in comparison with usual care for Thai smokers with cardiovascular disease. The study found that the FAHSAI Clinic was both clinically superior and cost-saving when compared to usual care in all scenarios.
TOBACCO INDUCED DISEASES
(2023)
Review
Allergy
Wasuchon Chaichan, Chidchanok Ruengorn, Kednapa Thavorn, Brian Hutton, Jacek C. Szepietowski, Jonathan A. Bernstein, Mati Chuamanochan, Surapon Nochaiwong
Summary: A systematic review and network meta-analysis were conducted to compare the safety profiles of different second-generation H1-antihistamines in patients with chronic urticaria. The study found variations in safety profiles, with mizolastine, emedastine, and cetirizine associated with unfavorable safety profiles.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE
(2023)
Article
Health Care Sciences & Services
Hassan Assem Mahmoud, Kednapa Thavorn, Sunita Mulpuru, Daniel McIsaac, Mohamed A. Abdelrazek, Amr Assem Mahmoud, Alan J. Forster
Summary: This study summarizes the barriers and facilitators perceived by hospital staff and physicians to influence the reporting, analysis, learning and feedback within patient safety learning systems (PSLS) in hospitals. Important barriers include inadequate organizational support, lack of training, weak safety culture, lack of accountability, defective policies, blame and punitive environment, complex system, lack of experience and lack of feedback. Enabling factors include continuous training, a balance between accountability and responsibility, leaders as role models, anonymous reporting, user-friendly systems, well-structured analysis teams, and tangible improvement. These findings provide insights for decision makers seeking to enhance the impact of PSLS.
Review
Medicine, General & Internal
Daniel Jones, Srishti Kumar, Caitlin Anstee, Molly Gingrich, Alexander Simone, Zubair Ahmadzai, Kednapa Thavorn, Andrew Seely
Summary: This study conducted a systematic review to evaluate the economic impact of adverse events following thoracic surgery. The results showed that the costs associated with these events are substantial and varied.
Article
Economics
Ratthanon Prasitwarachot, Kednapa Thavorn, Chanthawat Patikorn, Somkiat Wattanasirichaigoon, Suthat Rungruanghiranya, Araya Thongphiew, Nathorn Chaiyakunapruk
Summary: The study conducted a cost-effectiveness analysis (CEA) from a societal perspective to compare the cost-effectiveness of multidisciplinary services for COPD patients in Thailand with usual care. The results showed that FAH-SAI clinics were associated with higher costs but improved quality-adjusted life years (QALYs), with an incremental cost-effectiveness ratio of 37,675 THB/QALY (US$1,187/QALY).
JOURNAL OF MEDICAL ECONOMICS
(2023)
Article
Health Care Sciences & Services
Preshit Nemdas Ambade, Kednapa Thavorn, Smita Pakhale
Summary: This study aimed to assess the impact of COVID-19 lockdown on cases and healthcare costs in Maharashtra, India. The research found that the lockdown measures helped to slow down the spread of the virus and saved significant healthcare costs. However, it is recommended to carefully consider the local socio-economic realities when implementing such restrictions.
Article
Health Care Sciences & Services
Katina Zheng, Srishti Kumar, Aimee J. Sarti, Christophe L. Herry, Andrew J. E. Seely, Kednapa Thavorn
Summary: This study aimed to estimate the minimum percent change in failed extubation to make a tool designed to reduce extubation failure economically viable. The findings suggest that reducing the rate of extubation failure by 1% can lead to significant cost savings for hospitals. Clinical decision-support tools like the Extubation Advisor may play an important role in reducing healthcare costs.
INTERNATIONAL JOURNAL OF TECHNOLOGY ASSESSMENT IN HEALTH CARE
(2022)
Article
Geriatrics & Gerontology
Rafael N. Miranda, Aunima R. Bhuiya, Zak Thraya, Rebecca Hancock-Howard, Brian C. F. Chan, Carolyn Steele Gray, Walter P. Wodchis, Kednapa Thavorn
Summary: This study estimated the cost and cost utility of the electronic patient-reported outcome (ePRO) intervention compared to usual care for patients with multiple chronic conditions in Ontario, Canada. The findings showed that the ePRO intervention had higher costs and fewer quality-adjusted life years (QALYs) compared to standard care. However, if the ePRO intervention could improve at least 0.03 QALYs, it could be considered a cost-effective option. The study highlights the need for further research on the long-term outcomes and real-world impacts of ePRO interventions.
Review
Geriatrics & Gerontology
Kristina Marie Kokorelias, Michelle L. A. Nelson, Terence Tang, Carolyn Steele Gray, Moriah Ellen, Donna Plett, Carlotta Micaela Jarach, Jason Xin Nie, Kednapa Thavorn, Hardeep Singh
Summary: The study found that many older adult groups were excluded from digital health interventions and understudied. Characteristics of certain older adult groups, such as the oldest old and those with cognitive impairments, were neglected in the research. Additionally, there is limited information on characteristics related to gender diversity, education, race, ethnicity, and culture in the studies.