Article
Chemistry, Analytical
Yahui Guo, Mofan Wang, Fumiao Shen, Zhigang Hu, Hongliu Ding, Weirong Yao, He Qian
Summary: The self-fuelled amplification strategy (SFAS) proposed in this study involves concatenating two strand displacement amplification (SDA) processes to proliferate ssDNA, leading to a simple design and easy operation for sensing miRNA-21. The SFAS-based miRNA sensor showed a sensitivity of 1.78 x 10(-11) M, with recoveries ranging from 82.07% to 106.58% and an average RSD of 10.96% in the range of 0.02-1.0 x 10(-9) M.
ANALYTICAL METHODS
(2021)
Article
Chemistry, Multidisciplinary
Lijuan Qi, Meiting Yang, Dingran Chang, Wenjing Zhao, Sicai Zhang, Yan Du, Yingfu Li
Summary: The study presents a simple DNA detection platform that utilizes four techniques for the detection of infectious human diseases. The platform is highly specific and sensitive, capable of identifying genetic variations in clinical samples.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Analytical
Hua Chai, Mingyuan Wang, Longhai Tang, Peng Miao
Summary: An ultrasensitive electrochemical biosensor for miRNA assay was developed in this study, showing remarkable sensitivity and a wide linear range, as well as the capability to specifically discriminate interfering miRNAs with slightly different sequences.
ANALYTICA CHIMICA ACTA
(2021)
Article
Chemistry, Analytical
Yin Liu, Shiying Zhou, Human Sun, Jiangbo Dong, Liyuan Deng, Na Qi, Yongzhong Wang, Danqun Huo, Changjun Hou
Summary: A novel fluorescent biosensor based on CRISPR/Cpf 1-mediated PE-MC/SDA-CRISPR/Cpf1 amplification reaction was proposed for detecting the CaMV 35S promoter in genetically modified organisms. The method exhibited high detection sensitivity, low background interference, and excellent selectivity.
ANALYTICA CHIMICA ACTA
(2022)
Article
Chemistry, Analytical
Jingyi Chen, Jingzi Zhang, Qihui Xie, Zhaohui Chu, Fan Zhang, Qingjiang Wang
Summary: This study developed an efficient quantitative MCE method for detecting human breast cancer cell (MCF-7) exosomes assisted by triple amplification strategies combining cholesterol probe (Chol-probe) with SDA-CHA. The method enables sensitive and accurate quantification of tumor exosomes and has the potential to be applied for exosome detection in clinical samples.
Article
Chemistry, Analytical
Guoliang Zheng, Jiangshan Dai, Haiyan Wang, Ling Li, Deyu Yuan, Shujun Bai, Xu Song, Yongyun Zhao
Summary: HNESA is a novel signal amplification technique for nucleic acid detection which overcomes the limitations of traditional methods, demonstrates high sensitivity, can distinguish mismatched sequences, and has potential applications in complex biological samples.
Article
Chemistry, Analytical
Qiang Liu, Mei Liu, Yan Jin, Baoxin Li
Summary: Fluorescence biosensing based on CRISPR/Cas12a system with ratiometric probe as the reporter exhibits higher sensitivity compared to traditional TaqMan probe, and it can distinguish and avoid false positive signals.
Article
Chemistry, Analytical
Yaojia Liu, Yantian Shi, Kexin Ding, Jing Liu, Haiyan Wang, Hong Zhou
Summary: A hairpin DNA regulated strand displacement strategy is proposed for nucleic acid detection. In this entropy-driven signal amplification strategy, a hairpin structure is introduced into a duplex strand to facilitate the displacement process when the target DNA is present. The displacement of the single strand of the hairpin structure by the target DNA is a continuous process of displacing bases. This enzyme-free and cost-effective strategy has the potential to be a novel approach for clinical analysis.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Chemistry, Analytical
Ensheng Xu, Yahui Feng, Haitang Yang, Peng Li, Lu Kong, Wei Wei, Songqin Liu
Summary: The study developed an ultrasensitive multiple miRNAs detection strategy based on SDA and ACHA reactions, showing a linear relationship in the range of 0.1 fM to 10 fM for miRNA-122 and miRNA21 with low detection limits. The electrochemical sensor can be applied to detect other miRNAs by changing template strands, and the electrode can be regenerated by incubating with specific DNA strands.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Multidisciplinary
Feifei Luo, Xing Geng, Zhi Li, Ge Dai, Zhaohui Chu, Pingang He, Fan Zhang, Qingjiang Wang
Summary: A post-assembly CRISPR-Cas12a method based on target-induced transcription amplification and real-time crRNA generation has been proposed for bacterial 16S rDNA biosensing. This label-free method eliminates the requirement of a protospacer adjacent motif (PAM) on the target sequences, and shows potential as an effective and simple approach for nucleic acid detection and infectious disease diagnosis.
Article
Chemistry, Analytical
Linyan Li, Xiaojun Fang, Jingqing Le, Yanhui Zheng, Xiarong Tan, Zhou Jiang, Hongxia Li, Jianguo Xu, Huo Xu
Summary: In this study, a cascade catalytic hairpin assembly (CCHA) method was developed for sensitive and selective detection of miRNA. The method showed high assay sensitivity, excellent sequence specificity, and the ability for intracellular imaging, demonstrating promising potential for biosensing, clinical diagnosis, or prognosis.
Article
Spectroscopy
Yao Chen, Jin Yan, Xiaozhi Wang, Siwei Zhang, Jun Li, Ying Tang, Tong Wang
Summary: A fluorescence sensing method was developed for the quantification of alkaline phosphatase (ALP) by integrating strand displacement amplification with DNAzyme-catalytic recycling cleavage of molecular beacons. The proposed method achieved sensitive and specific ALP detection in human serum samples, showing potential for application in biomedical research and clinical diagnosis.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Biochemistry & Molecular Biology
Dawei Li, Shen Ling, Dudu Meng, Bing Zhou, Pengda Liang, Bei Lv
Summary: An ultrasensitive biosensor was developed for the detection of tobramycin, which exhibited high selectivity and could be applied in food safety control and environmental monitoring.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Chemistry, Analytical
Yan Zhang, Jinping Hu, Xiao-Yun Yang, Chun-yang Zhang
Summary: This method utilizes single-molecule detection and bidirectional strand displacement amplification to simultaneously detect UDG and hAAG with high sensitivity and good selectivity, enabling quantification of multiple DNA glycosylases at the single-cell level.
Article
Biotechnology & Applied Microbiology
Kang Shen, Weiwei Hua, Shengjie Ge, Yu Mao, Yuexing Gu, Gaoyang Chen, Youwei Wang
Summary: A novel surface-enhanced Raman scattering (SERS) biosensor was developed to detect telomerase for early diagnosis and prognosis assessment of hepatocellular carcinoma (HCC). The biosensor showed excellent reproducibility, specificity, and sensitivity, and was validated using ELISA as the golden standard.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Materials Science, Biomaterials
Cun Deng, Dong Dong, Tongyao Wang, Man Hu, Lijuan Sun, Xiuhua Zhang, Shengfu Wang, Huayu Xiong, Yong Chen, Jichao Liang
Summary: Cu2O/Pt nanocubes have been developed for the treatment of diabetic wounds, exhibiting good biocompatibility and antibacterial activity. They promote angiogenesis and wound healing by activating signaling pathways and enhancing cell proliferation and collagen deposition.
BIOMATERIALS ADVANCES
(2022)
Article
Engineering, Mechanical
Xiuhua Zhang, Huaiju Liu, Shaojie Wu, Gaomeng Li, Peitang Wei
Summary: There has been a growing interest in improving the reliability of machine components by enhancing their properties. Surface barrel finishing is a widely used technique to decrease surface roughness and improve mechanical properties. However, the effect of barrel finishing parameters on surface integrity is still unclear. This study experimentally investigated the effect of different finishing media and finishing time on the surface integrity of carburized rollers.
PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART E-JOURNAL OF PROCESS MECHANICAL ENGINEERING
(2022)
Article
Engineering, Mechanical
Xiuhua Zhang, Peitang Wei, Robert G. Parker, Guoliang Liu, Huaiju Liu, Shaojie Wu
Summary: This study investigates the relation between surface integrity and contact fatigue of gears. The results show that gears with high surface integrity exhibit the highest contact fatigue limit, which is 15.1% higher than gears with carburizing and grinding. Surface hardness, maximum compressive residual stress, and surface roughness are the most significant factors affecting contact fatigue life and fatigue limit. The proposed formulae have reasonable prediction accuracy for fatigue life and fatigue limit.
INTERNATIONAL JOURNAL OF FATIGUE
(2022)
Article
Cell Biology
Min Li, Chenxiang Wang, Zheng Yu, Qin Lan, Shaolin Xu, Zhongjiang Ye, Rongqi Li, Lili Ying, Xiuhua Zhang, Ziye Zhou
Summary: This study found that CRIZO treatment caused hepatic inflammatory injury, but magnesium isoglycyrrhizinate (MgIG) could alleviate this toxicity by activating the Nrf2/HO-1 pathway and inhibiting NF-kappa B activity.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
(2022)
Article
Chemistry, Analytical
Xi Zhang, Junlun Zhu, Zhen Wu, Wei Wen, Xiuhua Zhang, Shengfu Wang
Summary: An electrochemical sensor based on gold nano-particles and COFs was developed for the detection of BPA, showing high sensitivity and satisfactory recovery in real water samples.
ANALYTICA CHIMICA ACTA
(2023)
Review
Chemistry, Multidisciplinary
Yao Xiao, Chengyi Xiong, Miao-Miao Chen, Shengfu Wang, Lei Fu, Xiuhua Zhang
Summary: With the development of two-dimensional materials, transition metal dichalcogenides (TMDs) have become popular model materials for both fundamental sciences and practical applications. This review provides a comprehensive overview of the structure modulation of TMDs, including various modulated structures and their characteristics. It also summarizes the recent progress in modulating methods, mechanisms, properties, and applications of modulated TMD structures, as well as the challenges and prospects in this field.
CHEMICAL SOCIETY REVIEWS
(2023)
Article
Chemistry, Physical
Wenbo Li, Duoling Cao, Xiaorui Zhu, Zhiguang Guo, Li Wan, Xu Zhang, Xiuhua Zhang, Yuebin Li, Xiaoming Ren, Xianbao Wang, Dominik Eder, Shimin Wang
Summary: This study demonstrates a facile approach of optimizing the SnO2-ETL and CsPbI3 film to construct efficient carbon CE-based CsPbI3 solar cells, resulting in a relatively high power conversion efficiency of 12.85%.
ACS APPLIED ENERGY MATERIALS
(2023)
Article
Nanoscience & Nanotechnology
Xiaoxue Xi, Zhen Wu, Xiuhua Zhang, Yuebin Li, Yuandi Zhao, Wei Wen, Shengfu Wang
Summary: The development of a tumorspecific nanosensor with an endogenous protease-activatable manner remains a challenge in the in situ detection of low-content cancer biomarkers. This study proposes an endogenous protease-activatable nanosensor that combines electrochemical detection with optical imaging to achieve AND-gated and dual-model sensing of miRNA-21 in living tumor cells. The nanosensor can only be activated by dual keys simultaneously, improving the tumor-to-healthy cells ratio and providing new opportunities for the diagnosis and treatment of cancer at the single-cell level.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Multidisciplinary
Lebao Mao, Yao Xiao, Hao Liu, Xiuhua Zhang, Shengfu Wang, Wei-Hua Huang, Miao-Miao Chen
Summary: Hydrolysis-resistant CsPbBr3/reduced graphene oxide nanoscrolls (CsPbBr3/rGO NSs) with excellent optical properties and stability were obtained through a solvent-assisted self-rolling process. The CsPbBr3 QDs embedded in rGO nanosheets prevent water infiltration and maintain superb optical properties. The CsPbBr3/rGO NSs exhibit enhanced anode photocurrent response and demonstrate high sensitivity and anti-interference ability in molecular imprinted PEC sensors for mycotoxin detection.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Chemistry, Applied
Qian Wang, Chengyi Xiong, Jingwen Li, Qianchun Deng, Xiuhua Zhang, Shengfu Wang, Miao-Miao Chen
Summary: In this study, methylamine perovskite quantum dots (MP QDs) encapsulated by ZIF-8 metal-organic frameworks (MP QDs@ZIF-8) were prepared for the detection of aflatoxin B1 (AFB1). The constructed electrochemiluminescence (ECL) sensor showed good selectivity and ultra-sensitivity, with a wide linear range for AFB1 quantification. The satisfactory recoveries in corn samples demonstrated the reliable practicability of the proposed sensor for AFB1 assay. This work provided a novel pathway for designing high-performance ECL sensing platforms in food safety.
Article
Engineering, Mechanical
Huan Yan, Peitang Wei, Lihong Su, Huaiju Liu, Dong Wei, Xiuhua Zhang, Guanyu Deng
Summary: In this study, the rolling-sliding contact fatigue (RSCF) failures of AISI 9310 gear steel were thoroughly analyzed. The fatigue life, microstructure and crystallographic orientation evolution, and microhardness and residual stress distributions were characterized. The RSCF life of AISI 9310 steel roller decreased with increasing maximum contact pressure, but could be improved by shot peening due to enhanced microhardness and compressive residual stress. Main fatigue damage near the roller surface included inclined cracks, micro-pitting, spallation, and plastic deformation. The RSCF process also resulted in preferred crystallographic orientations.
INTERNATIONAL JOURNAL OF FATIGUE
(2023)
Article
Engineering, Multidisciplinary
Xiuhua Zhang, He Ke, Mingxin Chi, Ruochen Wang
Summary: In this study, the impact of paper straw board (PSB) on the seismic performance of cold-formed thin-walled steel composite walls (CFSCWs) was investigated, and the experimental results of CFSCW with PSB cladding were compared with those of CFSCW with other wall panel cladding. The findings suggest that PSB can effectively enhance the shear bearing capacity of the composite wall, and its lightweight nature makes CFSCW with PSB cladding easy to construct. Finite element analysis was conducted using ANSYS software to simulate CFSCW with one-sided PSB cladding and analyze the relevant parameters affecting seismic performance. The results indicate that reducing stud spacing, peripheral self-tapping screw spacing, increasing wall panel and steel skeleton edge stud section thickness can effectively improve shear bearing capacity and lateral stiffness within a certain range. Additionally, decreasing the wall height-to-width ratio improves lateral stiffness but decreases unit width shear bearing capacity.
JOURNAL OF THE CHINESE INSTITUTE OF ENGINEERS
(2023)
Article
Nanoscience & Nanotechnology
Weijian Wang, Gang Yu, Lebao Mao, Sanam Attique, Zhiwei Si, Qing Yang, Yongqiang Zhang, Guiqiu Huang, Haiyan Zhang, Ximing Yan, Shengfu Wang, Xiuhua Zhang
Summary: Researchers have designed perovskite solar cells with mesoporous antireflection coatings, which significantly improve the photocurrent density of the cells. The study offers a fresh approach to the development of highly efficient perovskite and perovskite/silicon tandem solar cells.
ADVANCED ELECTRONIC MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Jinrong Liu, Yongzhong Jiang, Wei Wen, Xiuhua Zhang, Zhen Wu, Shengfu Wang
Summary: A novel and universal single-particle collision electrochemistry (SPCE) biosensor based on the collision and oxidation of single silver nanoparticles (Ag NPs) was proposed for sensitive detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The biosensor showed enhanced detection sensitivity and practicability of SPCE in biosensing by increasing the collision frequency of Ag NPs on polysulfide-functionalized gold ultra-microelectrodes (Ps-Au UMEs). Additionally, the biosensor achieved successful detection of SARS-CoV-2 in nasopharyngeal swab samples, demonstrating its potential for clinically relevant diagnosis.
Article
Medicine, General & Internal
Xiuhua Zhang, Min Wang
Summary: This study aimed to investigate the clinical effect of high-quality nursing in patients with cirrhosis. The results showed that the application of whole-course high-quality nursing significantly improved the treatment effect, reduced hospitalization time and incidence of complications, and increased patient satisfaction.
ACTA MEDICA MEDITERRANEA
(2022)
Article
Biophysics
Reza Khodadadi, Manouchehr Eghbal, Hamideh Ofoghi, Alireza Balaei, Ali Tamayol, Karen Abrinia, Amir Sanati-Nezhad, Mohamadmahdi Samandari
Summary: This paper introduces an integrated portable centrifugal microfluidic system that automates cell and fluid manipulation for complete blood counting (CBC) analysis at the point-of-care (POC). The system utilizes a specially designed microfluidic disc for cell separation, solution metering and mixing, and cell counting, and is equipped with a custom script for automated quantification of cells. The proposed method shows a strong correlation with the gold standard hematology analyzer for various blood parameters. The portable system offers simplicity, affordability, and low power consumption, making it a potential solution for improving healthcare delivery in resource-limited settings and remote areas.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Nabil H. Bhuiyan, Joon S. Shim
Summary: Developing herd immunity is crucial for changing the course of the COVID-19 pandemic. An AI-driven point-of-care testing platform has been proposed for analyzing the body's response to SARS-CoV-2, and it has been successfully used for quantifying viral proteins and antibodies in blood samples. A data-receptive web-based dashboard system has also been developed for real-time analysis of herd immunity progress.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Alexiane Godain, Timothy M. Vogel, Pascal Fongarland, Naoufel Haddour
Summary: This study provides comprehensive insights into the intricate relationship between shear stress and electroactive biofilms in microbial fuel cells, highlighting the pivotal role of shear stress in influencing the growth kinetics, electrical performance, and physical structure of the biofilms. The study also emphasizes the complexities of extracellular electron transfer mechanisms and the need for complementary metaproteomic analyses.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Linjie Wang, Yixin Chen, Yang Ji, Shujun Zheng, Fei Wang, Caolong Li
Summary: A paper-based biosensor incorporating surface-enhanced Raman spectroscopy (SERS) and colorimetric detection has been developed for efficient quantification of intracellular glutathione (GSH). The biosensor exhibits excellent selectivity, stability, and precision, with low detection limits in both SERS and colorimetric modes. It has been successfully utilized for intracellular GSH detection and validated against a commercial GSH assay kit.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Quan Zhou, Jing Wang, Zhen Zhang, Alain Wuethrich, Richard J. Lobb, Matt Trau
Summary: This study presents a biosensor for sensitive detection of EMT-associated biomarkers on extracellular vesicles (EVs) surfaces during targeted therapy. Through longitudinal monitoring of patients, the biosensor shows its ability to identify the EMT-like phenotype switching on circulating EVs during the development of resistance.
BIOSENSORS & BIOELECTRONICS
(2024)
Review
Biophysics
Pratika Rai, Sabrina N. Hoba, Celine Buchmann, Robert J. Subirana-Slotos, Christian Kersten, Tanja Schirmeister, Kristina Endres, Bernd Bufe, Alexey Tarasov
Summary: Proteases have been proposed as potential biomarkers for various pathological conditions. The development of protease biosensors offers a more efficient way to investigate dysregulated proteases. This review article presents different optical and electrochemical detection methods for designing biosensors for all major protease families.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Chengxin Liu, Xu Shen, Li Yan, Runlian Qu, Yue Wang, Yaqin He, Zixuan Zhan, Piaopiao Chen, Feng Lin
Summary: In this study, a homogeneous rapid electrochemical aptasensor was developed to quantitatively detect CTCs in lung cancer patients. The aptasensor utilized a DNA nanosphere structure and a complementary aptamer to specifically detect mucin 1 as a marker for CTCs. The assay exhibited high specificity and sensitivity, and the results were consistent with other detection methods.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Danni Xue, Xing Dai, Jialong Zhao, Jiayao Zhang, Huan Liu, Kui Liu, Tao Xu, Chenjie Gu, Xingfei Zhou, Tao Jiang
Summary: In this study, a dual-enhancement SERS substrate based on Ti3C2TX and Ag nanocubes was fabricated for precise quantification of ritonavir and ibrutinib in serum. The formation of numerous electromagnetic hotspots between Ag nanocubes facilitated effective photo-induced charge transfer. The composite substrate showed excellent sensitivity, achieving low detection limits and high recoveries, making it promising for monitoring and identification of clinical blood drug concentration.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Tenghua Zhang, Zihui Xie, Xiaohe Zheng, Yuxin Liang, Yao Lu, Hankang Zhong, Feiyang Qian, Yuqing Zhu, Ruiting Sun, Yan Sheng, Jiaming Hu
Summary: This study reports a technology based on cationic lipid-polymer hybrid nanoparticles for efficient extracellular vesicle (EV) enrichment and in-situ detection of internal microRNAs. The technology demonstrates high EV enrichment efficiency and sensitive internal RNA detection, making it potentially useful for early pancreatic cancer diagnosis.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Wenjie Dai, Gaoxu Chen, Xiaoyan Wang, Shujun Zhen, Chengzhi Huang, Lei Zhan, Yuanfang Li
Summary: In this study, a novel metal organic gel (MOG) with dual electrochemiluminescence (ECL) properties was prepared by simple mixing. The MOG exhibited strong and stable anodic and cathodic ECL signals. By utilizing this MOG, an ECL resonance energy transfer (ECL-RET) biosensor was constructed for ultrasensitive detection of a specific gene. The study developed a straightforward technique for obtaining a single luminescent material with dual signals and expanded the analytical application of MOGs in the realm of ECL.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Lais Canniatti Brazaca, Amanda Hikari Imamura, Rodrigo Vieira Blasques, Jessica Rocha Camargo, Bruno Campos Janegitz, Emanuel Carrilho
Summary: The use of microfluidic paper-based analytical devices (muPADs) for medical diagnosis is a growing trend due to their low cost, easy use, simple manufacturing, and potential for application in low-resource settings. This review focuses on the advances in muPADs for medical diagnostics, discussing their use in detecting various biomarkers in common human biofluids. The challenges of biomarker detection in each sample are examined, along with innovative techniques to overcome these limitations. The commercialization difficulties of muPADs are also considered, along with future trends such as wearable devices and integrated platforms.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Minghong Jian, Xudong Sun, Hua Zhang, Xiaotong Li, Shasha Li, Zhenxin Wang
Summary: Matrix metalloproteinases (MMPs) are attractive biomarkers for cancer diagnosis and treatment, but their low abundance in biological samples, especially in the early stages of tumors, makes it challenging to precisely analyze MMP activities. In this study, a peptide microarray-based metal-enhanced fluorescence assay (PMMEFA) is proposed as a sensitive and specific method to simultaneously detect MMP-1, -2, -3, -7, -9, and -13 activities. The PMMEFA showed excellent sensitivity and was capable of detecting MMP activities in various matrices.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Kyung Ho Kim, Eunsu Ryu, Zinah Hilal Khaleel, Sung Eun Seo, Lina Kim, Yong Ho Kim, Hyun Gyu Park, Oh Seok Kwon
Summary: We have developed a novel strategy for discriminative detection of SARS-CoV-2 variants using the plasmonic photothermal effect of gold nanofilms and digital polymerase chain reaction (dPCR) technology. With this method, we were able to detect the delta and omicron variants with high sensitivity within 25 minutes from COVID-19 patients' clinical samples, making it a rapid and accurate point-of-care testing tool.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Zepeng Kang, Yuanming Wang, Haiyan Song, Xueli Wang, Job Zhang, Zhiguang Zhu
Summary: By designing a wearable and flexible lactic-acid/O2 EBFC with an air-breathing biocathode, the limitations of biocathode are effectively solved. The optimal performance conditions are determined through experiments, and the EBFC is successfully applied to power a low-power device.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Huayun Chen, Zhiheng You, Yuhui Hong, Xiao Wang, Mingming Zhao, Yushi Luan, Yibin Ying, Yixian Wang
Summary: This study developed a colorimetric sensor array using gas-responsive two-dimensional metal-organic framework (MOF) composites for highly sensitive detection of volatile organic compounds (VOCs). The dye/Zn-2(bim)(4) composites-based sensor arrays showed enhanced sensitivity and anti-interference properties. The findings demonstrate the potential use of dye/Zn-2(bim)(4) sensor arrays for early perception of plant diseases.
BIOSENSORS & BIOELECTRONICS
(2024)