4.8 Article

Low pressure supercritical CO2 extraction of astaxanthin from Haematococcus pluvialis demonstrated on a microfluidic chip

期刊

BIORESOURCE TECHNOLOGY
卷 250, 期 -, 页码 481-485

出版社

ELSEVIER SCI LTD
DOI: 10.1016/j.biortech.2017.11.070

关键词

Supercritical CO2 extraction; Astaxanthin; Microalgae; Microfluidics; Co-solvent

资金

  1. E.W.R. Steacie Memorial Fellowship from the Natural Science and Engineering Research Council of Canada
  2. Canada Research Chair in Microfluidics and Energy

向作者/读者索取更多资源

This study demonstrates the efficacy of low pressure supercritical CO2 extraction of astaxanthin from disrupted Haematococcus pluvialis. A microfluidic reactor was employed that enabled excellent control and allowed direct monitoring of the whole process at the single cell level, in real time. Astaxanthin extraction using ScCO2 achieved 92% recovery at 55 degrees C and 8 MPa applied over 15 h. With the addition of co-solvents, ethanol and olive oil, the extraction rates in both experiments were significantly improved reaching full recovery within a few minutes. Notably, for the ethanol case, the timescales of extraction process are reduced 1800-fold from 15 h to 30 s at 55 degrees C and 8 MPa, representing the fastest complete astaxanthin extraction at such low pressures.

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