Hexavalent chromium, a lung carcinogen, confers resistance to thermal stress and interferes with heat shock protein expression in human bronchial epithelial cells

Development of a toxicogenomics signature for genotoxicity using a dose-optimization and informatics strategy in human cells

(2015) Heng-Hong Li et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Hsf1 Is Required for the Nuclear Translocation of p53 Tumor Suppressor

(2015) Qiang Li et al.   NEOPLASIA

Impact of hexavalent chromium on mammalian cell bioenergetics: phenotypic changes, molecular basis and potential relevance to chromate-induced lung cancer

(2014) P. L. Abreu et al.   BIOMETALS

Short-term exposure of nontumorigenic human bronchial epithelial cells to carcinogenic chromium(VI) compromises their respiratory capacity and alters their bioenergetic signature

(2014) Joana F. Cerveira et al.   FEBS Open Bio

The Complex Function of Hsp70 in Metastatic Cancer

(2013) Kata Juhasz et al.   Cancers

Heat shock proteins and heat shock factor 1 in carcinogenesis and tumor development: an update

(2012) Daniel R. Ciocca et al.   ARCHIVES OF TOXICOLOGY

Transcriptomic analysis of grape (Vitis vinifera L.) leaves during and after recovery from heat stress

(2012) Guo-Tian Liu et al.   BMC PLANT BIOLOGY

HSF1 Drives a Transcriptional Program Distinct from Heat Shock to Support Highly Malignant Human Cancers

(2012) Marc L. Mendillo et al.   CELL

The effects of chromium(VI) on the thioredoxin system: Implications for redox regulation

(2012) Charles R. Myers   FREE RADICAL BIOLOGY AND MEDICINE

Hexavalent chromium targets mitochondrial respiratory chain complex I to induce reactive oxygen species-dependent caspase-3 activation in L-02 hepatocytes

(2012) FANG XIAO et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Hexavalent chromium induces energy metabolism disturbance and p53-dependent cell cycle arrest via reactive oxygen species in L-02 hepatocytes

(2012) Fang Xiao et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

BRCA1 and HSP90 cooperate in homologous and non-homologous DNA double-strand-break repair and G2/M checkpoint activation

(2012) S. R. Stecklein et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of Hsp90 in protein complex assembly

(2011) Taras Makhnevych et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Curcumin prevents Cr(VI)-induced renal oxidant damage by a mitochondrial pathway

(2011) Eduardo Molina-Jijón et al.   FREE RADICAL BIOLOGY AND MEDICINE

Inhibitory effect of SJSZ glycoprotein (38 kDa) on expression of heat shock protein 27 and 70 in chromium (VI)-treated hepatocytes

(2011) Jin Lee et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Selective killing of cancer cells by a small molecule targeting the stress response to ROS

(2011) Lakshmi Raj et al.   NATURE

Hexavalent chromium-induced apoptosis of granulosa cells involves selective sub-cellular translocation of Bcl-2 members, ERK1/2 and p53

(2011) Sakhila K. Banu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Changes in glucose uptake rate and in the energy status of PC-12 cells acutely exposed to hexavalent chromium, an established human carcinogen

(2011) Maria João Gonçalves et al.   TOXICOLOGICAL AND ENVIRONMENTAL CHEMISTRY

The pro-oxidant chromium(VI) inhibits mitochondrial complex I, complex II, and aconitase in the bronchial epithelium: EPR markers for Fe–S proteins

(2010) Charles R. Myers et al.   FREE RADICAL BIOLOGY AND MEDICINE

Induction of morphological changes in BEAS-2B human bronchial epithelial cells following chronic sub-cytotoxic and mildly cytotoxic hexavalent chromium exposures

(2010) André N. Costa et al.   MOLECULAR CARCINOGENESIS

Heavy metals chromium and neodymium reduced phosphorylation level of heat shock protein 27 in human keratinocytes

(2010) Qihao Zhang et al.   TOXICOLOGY IN VITRO

Bioenergetics and DNA alteration of normal human fibroblasts by hexavalent chromium

(2009) W. Liu et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

The effects of hexavalent chromium on thioredoxin reductase and peroxiredoxins in human bronchial epithelial cells

(2009) Judith M. Myers et al.   FREE RADICAL BIOLOGY AND MEDICINE

Human bronchial epithelial cells malignantly transformed by hexavalent chromium exhibit an aneuploid phenotype but no microsatellite instability

(2009) C.F.D. Rodrigues et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

A purine scaffold Hsp90 inhibitor destabilizes BCL-6 and has specific antitumor activity in BCL-6–dependent B cell lymphomas

(2009) Leandro C Cerchietti et al.   NATURE MEDICINE

Heat shock factor-1 modulates p53 activity in the transcriptional response to DNA damage

(2009) Ian R. Logan et al.   NUCLEIC ACIDS RESEARCH

RNA-binding proteins and post-transcriptional gene regulation

(2008) Tina Glisovic et al.   FEBS LETTERS

Turnover of the Human Proteome: Determination of Protein Intracellular Stability by Dynamic SILAC

(2008) Mary K. Doherty et al.   JOURNAL OF PROTEOME RESEARCH

Proteomic analysis of chromium cytotoxicity in cultured rat lung epithelial cells

(2008) Ting Lei et al.   PROTEOMICS

Hexavalent chromium causes the oxidation of thioredoxin in human bronchial epithelial cells

(2008) Judith M. Myers et al.   TOXICOLOGY

Regulation of protein turnover by acetyltransferases and deacetylases

(2007) Karin Sadoul et al.   BIOCHIMIE

Genetic and Epigenetic Mechanisms in Metal Carcinogenesis and Cocarcinogenesis: Nickel, Arsenic, and Chromium

(2007) Konstantin Salnikow et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Genomic and Proteomic Profiling of Responses to Toxic Metals in Human Lung Cells

(2003) Angeline S. Andrew et al.   ENVIRONMENTAL HEALTH PERSPECTIVES