期刊
BIOINFORMATICS
卷 35, 期 3, 页码 521-522出版社
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/bty630
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资金
- Swedish Research Council [2015-03443_VR]
- Swedish Research Council [2015-03443] Funding Source: Swedish Research Council
Motivation: The accurate in silico simulation of metagenomic datasets is of great importance for benchmarking bioinformatics tools as well as for experimental design. Users are dependant on large-scale simulation to not only design experiments and new projects but also for accurate estimation of computational needs within a project. Unfortunately, most current read simulators are either not suited for metagenomics, out of date or relatively poorly documented. In this article, we describe InSilicoSeq, a software package to simulate metagenomic Illumina sequencing data. InsilicoSeq has a simple command-line interface and extensive documentation. Results: InSilicoSeq is implemented in Python and capable of simulating realistic Illumina (meta) genomic data in a parallel fashion with sensible default parameters.
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