Article
Engineering, Environmental
Bahar Baniasadi, Farzaneh Vahabzadeh
Summary: Using Anabaena vaginicola cyanobacterial biomass as the anodic substrate in double chamber MFCs can improve bioelectricity generation through pretreatment of the biomass and addition of riboflavin. Pretreatment and addition of riboflavin can increase maximum power density, and enhance the utilization efficiency of biomass by S. oneidensis MR-1 cells.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2021)
Article
Biotechnology & Applied Microbiology
Miriam Edel, Gunnar Sturm, Katrin Sturm-Richter, Michael Wagner, Julia Novion Ducassou, Yohann Coute, Harald Horn, Johannes Gescher
Summary: This study identified a new quorum-sensing mechanism in S. oneidensis, where riboflavin production and excretion trigger biofilm formation by upregulating proteins involved in the process. The findings could be utilized for developing strains that generate higher current densities in bioelectrochemical systems.
BIOTECHNOLOGY FOR BIOFUELS
(2021)
Article
Multidisciplinary Sciences
Feng Li, Rui Tang, Baocai Zhang, Chunxiao Qiao, Huan Yu, Qijing Liu, Junqi Zhang, Liang Shi, Hao Song
Summary: Researchers systematically engineered Shewanella oneidensis, an exoelectrogenic model organism, to promote biofilm formation and enhance biofilm conductivity in microbial electrochemical systems. The engineered biofilm achieved a maximum output power density of 3.62 +/- 0.06 W m-2, 39.3 times higher than that of the wild-type strain, setting a new record for the output power density of genetically engineered Shewanella biofilms.
Article
Microbiology
Shan Chen, Yuanzhao Ding
Summary: This study uses a bibliography study method to evaluate 472 papers focused on Shewanella oneidensis biofilms. Biofilms play a crucial role in various settings and this paper provides a comprehensive examination and review of the biology and engineering aspects of Shewanella biofilms, offering valuable insights into their functionality.
FEMS MICROBIOLOGY ECOLOGY
(2023)
Article
Biotechnology & Applied Microbiology
Akiho Matsumoto, Ryota Koga, Robert A. Kanaly, Atsushi Kouzuma, Kazuya Watanabe
Summary: In medium flow conditions, Shewanella oneidensis MR-1 utilizes DgcS to synthesize c-di-GMP, thereby activating biofilm formation on electrode surfaces.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
(2021)
Article
Chemistry, Physical
Hue Ngan Dai, Tam-Anh Duong Nguyen, L. E. Loan-Phung My, Man Van Tran, Tzu-Hsuan Lan, Chin-Tsan Wang
Summary: This study demonstrates the successful recovery of energy from the effluent of hydrogen fermentation by generating electrical power in batch dual-chamber microbial fuel cells inoculated with Shewanella oneidensis MR-1. The performance of MFC was found to be influenced by the addition of lactate in the wastewater, with MFC without lactate addition exhibiting better performance in terms of voltage generation and COD removal.
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
(2021)
Article
Chemistry, Multidisciplinary
Yao Li, Sen Qiao, Meiwei Guo, Caiyun Hou, Jingxuan Wang, Cong Yu, Jiti Zhou, Xie Quan
Summary: Ammonia production is achieved in a microbial electrosynthesis system using nitrate and an electrode as electron acceptors and donors. With the help of She-wanella oneidensis MR-1, the system achieves a high ammonia production rate of 24.3 mg h-1$mg protein -1 with 82.5% selectivity and 33.1% cathodic efficiency. The electrochemical analysis indicates the important roles of cytochromes c, flavins, and the flavin/c-cytochrome combination. The work proposes a progressive route for ammonia synthesis under mild conditions.
CELL REPORTS PHYSICAL SCIENCE
(2023)
Article
Environmental Sciences
Changdong Ke, Chuling Guo, Siyu Zhang, Yanping Deng, Xiaofei Li, Yuancheng Li, Guining Lu, Fei Ling, Zhi Dang
Summary: This study investigated the reduction of Schwertmannite (Sch) by the co-culture of iron-reducing bacteria (FeRB) and sulfate-reducing bacteria (SRB). The results showed that the co-culture could accelerate the reductive dissolution of Sch, but not synergistically. The reduction of Sch mediated by FeRB and SRB had two distinct phases.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Environmental Sciences
Ola M. Gomaa, Nabila S. Selim, Reham Fathy, Heba Hamed
Summary: The addition of palladium alpha-lipoic acid nanocomplex compound (PLAC) was found to increase bacterial cell membrane permeability and outer cell surface charge, facilitating biofilm formation and interfacial electron transfer.
ENVIRONMENTAL TECHNOLOGY
(2021)
Review
Biochemistry & Molecular Biology
Atsushi Kouzuma
Summary: Electrochemically active bacteria (EAB) interact with electrodes via extracellular electron transfer (EET) pathways, dependent on carbon catabolism and respiration regulation, with biofilm formation being crucial for electric current generation.
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
(2021)
Article
Agricultural Engineering
Ankit Kumar, Soumya Pandit, Kalpana Sharma, Abhilasha Singh Mathuriya, Ram Prasad
Summary: This study investigates the microbial degradation of xylan using Bacillus sp. isolated from wastewater. Co-culture and electrode modification were found to enhance the degradation of xylan and increase power output in a microbial fuel cell (MFC) under optimal conditions.
BIORESOURCE TECHNOLOGY
(2023)
Article
Green & Sustainable Science & Technology
Dan Luo, Hong Ding, Ting Guo, Xiangling Li, Tianshun Song, Jingjing Xie
Summary: Microbial electrosynthesis (MES) is an attractive technology for converting CO2 into chemicals. It was found in this study that using a conductive bio-abiotic composite as the cathode can enhance the rate and yield of hydrogen evolution reaction.
Article
Microbiology
Xiao Zhu, Fei Dou, Mingliang Long, Xinxin Wang, Wei Liu, Fangbai Li, Tongxu Liu, Yundang Wu
Summary: This study found that AQS can promote both biofilm formation and electron shuttling in S. oneidensis MR-1, but excessive AQS may hinder biofilm formation. The results also demonstrated that microbial-catalyzed ES bio-reduction is the key limiting factor of the maximum biocurrent density in BESs.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Biotechnology & Applied Microbiology
Yixin Li, Qingliu Luo, Jiaying Su, Guowen Dong, Mingfeng Cao, Yuanpeng Wang
Summary: In this study, the performance of Shewanella oneidensis MR-1 in microbial electrosynthesis (MES) was enhanced through the regulation and overexpression of key genes involved in extracellular electron uptake (EEU) and intracellular CO2 conversion processes. The results revealed the mechanism of MES in S. oneidensis MR-1 and provided insights for genetic improvements in the further application of MES.
METABOLIC ENGINEERING
(2023)
Review
Biochemistry & Molecular Biology
Sota Ikeda, Yuki Takamatsu, Miyu Tsuchiya, Keigo Suga, Yugo Tanaka, Atsushi Kouzuma, Kazuya Watanabe
Summary: The genus Shewanella includes various heterotrophic bacteria, some pathogenic and others essential in the global carbon cycle. The representative strain Shewanella oneidensis MR-1 has versatile respiratory capacities and electrochemical activity, making it a focus of research for applications in electro-biotechnology.
MICROBIAL CELL FACTORIES-BOOK
(2021)
Article
Engineering, Biomedical
Dounia Dems, Ronit Freeman, Kyle D. Riker, Thibaud Coradin, Samuel Stupp, Carole Aime
Summary: By combining peptide amphiphile nanofibers and silica nanoparticles, it is possible to design biomaterials with tunable bioactive epitopes for improved cell adhesion and spreading on hydrogels. The synergy between different integrin-binding sequences on nanoparticle surfaces can enhance cell adhesion in composite materials with soft and hard nanostructures.
ACTA BIOMATERIALIA
(2021)
Article
Biochemistry & Molecular Biology
Nicolas Debons, Kenta Matsumoto, Noriyuki Hirota, Thibaud Coradin, Toshiyuki Ikoma, Carole Aime
Summary: The study involves the preparation of bionanocomposites from tilapia fish scale collagen and multifunctional silica nanoparticles under high magnetic field, showing the potential of these scaffolds to improve cell performance.
Article
Engineering, Biomedical
Sophie Maillard, Ludovic Sicard, Caroline Andrique, Coralie Torrens, Julie Lesieur, Brigitte Baroukh, Thibaud Coradin, Anne Poliard, Lotfi Slimani, Catherine Chaussain
Summary: Combining implantation of dense collagen hydrogels hosting murine dental pulp stem cells (mDPSC) with systemic injections of a sclerostin antibody leads to increased bone regeneration in large bone defects. The study also suggests that implantation of sclerostin-deficient MSC promotes new bone formation similarly to complete sclerostin deficiency.
ACTA BIOMATERIALIA
(2022)
Article
Biochemistry & Molecular Biology
Kun Wang, Marie Camman, Gervaise Mosser, Bernard Haye, Lea Trichet, Thibaud Coradin
Summary: A new protocol for preparing fibrin-collagen composite gels is described, showing potential as biomaterials. The addition of collagen increases the turbidity of the gels and reduces their shrinkage, with minimal influence on the rheological properties. Collagen fibers are observed within the fibrin network. Collagen favors cell proliferation and alignment, but interferes with cell differentiation and myotube formation.
Article
Multidisciplinary Sciences
Nicolas Obtel, Adeline Le Cabec, The Nghia Nguyen, Eloise Giabicani, Stijn J. M. Van Malderen, Jan Garrevoet, Aline Percot, Celine Paris, Christopher Dean, Smail Hadj-Rabia, Pascal Houillier, Tilman Breiderhoff, Claire Bardet, Thibaud Coradin, Fernando Ramirez Rozzi, Catherine Chaussain
Summary: Claudin proteins are crucial for determining the permeability and ion specificity of tight junctions in epithelia. Deficiency in claudin-10 is associated with severe enamel wear in HELIX syndrome patients. Analysis of a HELIX patient's molar revealed accentuated strontium variations in the enamel and dentin, possibly indicating episodes of worsening renal dysfunction.
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES
(2022)
Article
Chemistry, Multidisciplinary
Estelle Palierse, Sylvie Masse, Guillaume Laurent, Patrick Le Griel, Gervaise Mosser, Thibaud Coradin, Claude Jolivalt
Summary: This study compared two methods, adsorption and in situ incorporation, for preparing hybrid polyphenol/hydroxyapatite nanoparticles. The results showed that adsorption of polyphenols on pre-formed nanoparticles did not change their properties, while in situ incorporation inhibited hydroxyapatite formation but resulted in higher loadings. Most hybrid particles exhibited a burst effect followed by slow release over time.
Article
Robotics
Mouna Ben Salem, Laurent Petit, Muneeb Ullah Khan, Jeremy Terrien, Christine Prelle, Frederic Lamarque, Thibaud Coradin, Christophe Egles
Summary: In this paper, a concept of an implantable drug delivery device capable of delivering drugs in the duodenum for a long period of time is presented. The device aims to address therapeutic non-adherence, which is a major barrier to patients receiving the full benefits of their medications. The device is based on a miniature tubular linear actuator that can move at discrete positions inside a tube, and the research work primarily focuses on the actuator design and validation.
JOURNAL OF MICRO-BIO ROBOTICS
(2023)
Article
Engineering, Biomedical
Sophia Houari, Karen Derocher, Tran Thu Thuy, Thibaud Coradin, Vesna Srot, Peter A. van Aken, Helene Lecoq, Thierry Sauvage, Etienne Balan, Julie Aufort, Marco Calemme, Nicolas Roubier, Julia Bosco, Katia Jedeon, Ariane Berdal, Derk Joester, Sylvie Babajko
Summary: Developmental Defects of Enamel (DDE), such as Dental Fluorosis (DF) and Molar Incisor Hypomineralization (MIH), are a significant public health problem. This study used a combination of structural and chemical methods to compare and study MIH, DF, and healthy teeth from 89 patients. The results show that DF is characterized by a homogeneous loss of mineral content and crystallinity on the outer layer of enamel, while MIH is associated with localized defects in the depth of enamel. Minor differences in elemental composition were detected at the nanoscale. The study also proposes the use of colorimetric measurements for clinical diagnosis and improved restoration protocols. The findings contribute to a better understanding of DDE and provide insights for personalized dentistry.
ACTA BIOMATERIALIA
(2023)
Review
Polymer Science
Enguerran Devernois, Thibaud Coradin
Summary: Type I collagen and chitosan are commonly used biological macromolecules for tissue engineering scaffolds. While collagen is biocompatible and provides biochemical cues, it has poor mechanical properties. Chitosan, on the other hand, is more versatile but not a good substrate for mammalian cells. Combining these two biomacromolecules allows for the preparation of interesting biomaterials with improved properties. However, there is a lack of understanding regarding chitosan-type I collagen interactions.
Article
Materials Science, Multidisciplinary
Anastasia Permyakova, Alshaba Kakar, Jonathan Bachir, Effrosyni Gkaniatsou, Bernard Haye, Nicolas Menguy, Farid Nouar, Christian Serre, Nathalie Steunou, Thibaud Coradin, Francisco M. Fernandes, Clemence Sicard
Summary: The mesoporous iron polycarboxylate MIL-100(Fe) was synthesized with the presence of Pseudomonas putida bacteria. The synthesis was done under green conditions, using pure aqueous media at 30 degrees C to ensure the integrity of the cell membrane. The resulting biohybrid showed a unique microstructure, with an exoskeleton encapsulating individual bacteria cell, suggesting strong interactions between the exopolysaccharides network and MOF precursors.
ACS MATERIALS LETTERS
(2023)
Article
Chemistry, Physical
Stephanie De Oliveira, Gregor Miklosic, Joelle Veziers, Sebastien Grastilleur, Thibaud Coradin, Catherine Le Visage, Jerome Guicheux, Matteo DEste, Christophe Helary
Summary: Collagen/hyaluronan composite hydrogels with physical properties suitable for biomedical applications can be synthesized by inhibiting the formation of polyionic complexes.
Article
Nanoscience & Nanotechnology
Kankan Qin, Rui F. P. Pereira, Thibaud Coradin, Veronica de Zea Bermudez, Francisco M. Fernandes
Summary: This study demonstrates the fabrication of three-dimensional porous silk foams as dermal patches for wound protection and controlled delivery of antibiotics. The silk foams exhibit good water wicking capacity, deformability, and antibacterial behavior. The method of reassembling natural materials as macroporous foams can be applicable to other multicomponent natural materials, playing a crucial role in applications involving controlled release of molecules and fluid transport.
ACS APPLIED BIO MATERIALS
(2022)
Article
Nanoscience & Nanotechnology
Kankan Qin, Rui F. P. Pereira, Thibaud Coradin, Veronica de Zea Bermudez, Francisco M. Fernandes
Summary: Silk from Bombyx mori has a unique arrangement of its two major components, which provides mechanical and surface properties for protecting the moth during its vulnerable phase. By reshaping the silk fibers into macroporous foam structures, this study demonstrates the potential of using these silk foams as dermal patches for wound protection and controlled drug delivery. This method can be extended to other natural materials and play a crucial role in applications involving controlled release and fluid transport.
ACS APPLIED BIO MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Sarah Christoph, Pierre Barre, Bernard Haye, Thibaud Coradin, Francisco M. Fernandes
Summary: We present a new class of hybrid material composed of a polysaccharide macroporous core surrounded by a thin silica layer, which can be used as adsorption platforms for organic pollutants in soil. These hybrid materials showed structural stability and sorption capacity for organic pollutants significantly higher than the surrounding soils. They possess all the necessary properties to be effective materials for soil depollution and are easy to recover.
Review
Materials Science, Biomaterials
Davy-Louis Versace, Louise Breloy, Estelle Palierse, Thibaud Coradin
Summary: Surgical site infections are a major health concern that can be addressed by imparting antibacterial properties to surgical tools and medical devices. Bio-sourced polymers are well-suited for preparing such coatings, with photochemistry being highlighted as a green and mild methodology for developing bio-based antibacterial materials. Efforts are ongoing to optimize sustainability, improve safety, and extend strategies to 3D biomaterials.
JOURNAL OF MATERIALS CHEMISTRY B
(2021)
Article
Biochemistry & Molecular Biology
Priyanga Kumar, Noel Nesakumar, Jayashree Gopal, Sakthivel Sivasubramanian, Srinivasan Vedantham, John Bosco Balaguru Rayappan
Summary: This study developed an electrochemical biosensor for measuring MG levels in the plasma of type-2 diabetes mellitus patients. The biosensor showed a wide linear concentration range, high sensitivity, and a 90% correlation with ELISA data. It also exhibited a significant correlation with HbA1c and fasting plasma glucose levels.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Cristina Tortolini, Valeria Gigli, Antonio Angeloni, Federico Tasca, Nguyen T. K. Thanh, Riccarda Antiochia
Summary: The development of a novel voltammetric immunosensor for the detection of salivary MMP-8 at the point-of-care is described. The sensor showed good performance and comparable results to the conventional ELISA method when tested in real saliva samples. This biosensor is single-use, cost-effective, and requires a small quantity of test medium and a short preparation time.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Rimsha B. Jamal, Ulrich Bay Gosewinkel, Elena E. Ferapontova
Summary: Pathogen-triggered infections are a severe global threat to human health. Researchers have developed a fast and inexpensive electrocatalytic aptamer assay for the specific and ultrasensitive detection of E. coli, allowing for timely treatment and prevention. The method is fast, sensitive, and can be used in field and point-of-care applications for analysis of bacteria in the human environment.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Miao Liu, Yuwei Wang, Shanshan Tang, Wei Wang, Axin Liang, Aiqin Luo
Summary: An unlabeled ratiometric molecular imprinted electrochemiluminescence sensor was developed for the determination of trace uric acid using MXene@NaAsc, CdSe@ZnS quantum dots, and molecularly imprinted polymer composites modified glass carbon electrode. This sensor, with easy preparation, great selectivity, and excellent sensitivity, successfully detected uric acid in human serum.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Charlotte Da Silva, Camille Lamarche, Carole Pichereaux, Emmanuelle Mouton-Barbosa, Gauthier Demol, Sebastien Boisne, Etienne Dague, Odile Burlet-Schiltz, Flavien Pillet, Marie-Pierre Rols
Summary: Low-energy electron beams (LEEB) are a safe and practical sterilization solution for industrial applications. To address the limitations of LEEB, we developed a low-energy pulsed electron beam generator (LEPEB) that can effectively and efficiently eradicate bacteria in a wide range of industrial applications.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Daniel Dobrovodsky, Ales Danhel, Daniel Renciuk, Jean-Louis Mergny, Miroslav Fojta
Summary: In this study, N-methyl mesoporphyrin IX (NMM) was utilized as a voltammetric probe for the electrochemical detection of G4s. The detection of NMM was achieved by cyclic voltammetry on a hanging mercury drop electrode (HMDE) with a limit of detection (LOD) of 40 nM. The reduction signal of NMM was found to be significantly higher when G4 oligodeoxynucleotides (G4 ODNs) were present compared to single- or double-stranded ODNs or unfolded ODNs capable of forming G4s. Gradual transition from unstructured single strand to G4, induced by increasing concentrations of the G4 stabilizing K+ ions, was detected for the first time using electrochemical methods. Circular dichroism spectroscopy provided support for the obtained results. This work expands on the utilization of electrochemical probes for DNA secondary structure recognition and offers a proof of principle for the development of novel electroanalytical methods for nucleic acid structure studies.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Mengjiao Zhu, Yu Liu, Meiyue Wang, Tao Liu, Zhenyu Chu, Wanqin Jin
Summary: Early rapid diagnosis of COVID-19 is crucial for reducing the risk of severe symptoms and loss of lung function. Researchers have proposed an ultrafast and ultrasensitive DNA sensor that can accurately detect the virus in a short period of time, with outstanding selectivity.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Fatima-Zahra Ait-Itto, James A. Behan, Mathieu Martinez, Frederic Barriere
Summary: This study investigated the feasibility of using ancient marine sediments as inoculum for bioanode development in microbial fuel cells (MFC). The results showed the presence of two exoelectrogenic bacterial genera in these iron-rich sediments and confirmed that the development of the bioanode derived from the native microbiota. This study has important implications for understanding the role of these bacteria in broader paleoenvironmental phenomena.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Issa Fall, Bastien Doumeche, Sofiene Abdellaoui, Caroline Remond, Harivony Rakotoarivonina, Marjorie Ochs
Summary: This article presents a novel electrochemical tool based on lignin-coated paper electrodes for the detection and characterization of ligninolytic activity. The suitability of this method has been demonstrated using a catalaseperoxidase isolated from Thermobacillus xylanilyticus.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Chenyi Zhuo, Dehong Yu, Jiuying Cui, Zichun Song, Qianli Tang, Xianjiu Liao, Zhao Liu, Ning Xin, Lu Lou, Fenglei Gao
Summary: A label-free detection strategy for quantification of Apolipoprotein A4 (Apo-A4) has been developed based on rolling circle amplification (RCA) and proximity hybridization-induced DNAzyme-driven bipedal DNA walker. This method shows high sensitivity and selectivity for a wide range of protein targets.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Niloufar Fattahi, Jeffrey Reed, Evan Heronemus, Priyasha Fernando, Ryan Hansen, Prathap Parameswaran
Summary: In this study, polyethylene glycol hydrogels were developed as protective coatings for electroactive biofilms, improving their viability under low resource conditions and ammonia-N shocks.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Xiaopeng Hou, Qiongyi Cheng, Hui Wang
Summary: A self-cleaning paper-based microfluidic biosensor was developed using hydrophobic paper decorated with polymeric octadecyl trichlorosilane. The biosensor showed improved performance and could effectively measure the concentration of copper ions in livestock feed and manure.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Yanling Zhang, Jie Wang, Min Liu, Yun Ni, Yao Yue, Dawei He, Ruijiang Liu
Summary: An innovative electrochemical biosensor has been developed for sensitive detection of HER2 protein, an important tumor marker for breast cancer diagnosis and treatment evaluation. The biosensor utilizes specific recognition probes and nanomaterials, along with a unique sensing strategy, to achieve ultra-low detection limit and demonstrate excellent selectivity, reproducibility, and stability.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Humayun Amir, Vasanth Subramanian, Sundaram Sornambikai, Nagamony Ponpandian, Chinnusamy Viswanathan
Summary: In this study, the electrochemical detection of breast cancer biomarker HER2 was successfully achieved using the N-CQDs/GS as the detector. The BSA-modified HER2 Antibody/N-CQDs/GS immunoelectrode preserved excellent activity for the biosensor, while the GS electrode provided high stability and conductivity. The method exhibited a low detection limit and optimal specificity, stability, and reproducibility for detecting HER-2 protein in untreated blood samples from breast cancer patients.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Ilona Uzieliene, Anton Popov, Raminta Vaiciuleviciute, Gailute Kirdaite, Eiva Bernotiene, Almira Ramanaviciene
Summary: This review discusses the application of polypyrrole (Ppy), an electroconductive polymer, in cell culture experiments with electrical stimulation (ES) and its potential for tissue regeneration. Ppy can direct ES to cells and stimulate differentiation towards different cell lineages. Different types of Ppy materials and their combination with active molecules are explored.
BIOELECTROCHEMISTRY
(2024)