4.5 Article

Lipids in human milk

出版社

ELSEVIER SCI LTD
DOI: 10.1016/j.beem.2017.11.002

关键词

milk fat; long-chain polyunsaturated fatty acid; milk-fat-globule membrane; palmitic acid; stable isotope tracer

资金

  1. Commission of the European Community
  2. 7th Framework Programme Early Nutrition [FP7-289346]
  3. Horizon Research and Innovation Programme DYNAHEALTH [633595]
  4. European Research Council Advanced Grant META-GROWTH (ERC-AdG) [322605]
  5. European Research Council (ERC) [322605] Funding Source: European Research Council (ERC)

向作者/读者索取更多资源

Fat is the main energy providing component in human milk and comprising a complex mixture of different lipid species, with quantitative dominance of triglycerides. After elucidating the fatty acid composition, more recent research has looked at influencing factors and the importance of specific lipids. Here we review quantitative aspects of maternal metabolism which contribute to the milk fatty acid composition, especially considering essential fatty acids and their long chain polyunsaturated derivatives. In this context studies with stable isotopes have indicated the importance of maternal body pools for mediating the effects of diet on milk composition. Furthermore, the importance of positioning of palmitic acid at the glycerol backbone of triglycerides is discussed, and the phospholipids of the milk fat globule membrane are described and examples for their potential importance for infant development are presented. (C) 2017 Elsevier Ltd. All rights reserved.

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